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2,150 Results Found

  • Review
  • Open Access
88 Citations
14,325 Views
20 Pages

Promoter Architecture and Promoter Engineering in Saccharomyces cerevisiae

  • Hongting Tang,
  • Yanling Wu,
  • Jiliang Deng,
  • Nanzhu Chen,
  • Zhaohui Zheng,
  • Yongjun Wei,
  • Xiaozhou Luo and
  • Jay D. Keasling

6 August 2020

Promoters play an essential role in the regulation of gene expression for fine-tuning genetic circuits and metabolic pathways in Saccharomyces cerevisiae (S. cerevisiae). However, native promoters in S. cerevisiae have several limitations which hinde...

  • Article
  • Open Access
3 Citations
3,503 Views
17 Pages

Further Insights into the Architecture of the PN Promoter That Controls the Expression of the bzd Genes in Azoarcus

  • Gonzalo Durante-Rodríguez,
  • Paloma Gutiérrez-del-Arroyo,
  • Marisela Vélez,
  • Eduardo Díaz and
  • Manuel Carmona

27 June 2019

The anaerobic degradation of benzoate in bacteria involves the benzoyl-CoA central pathway. Azoarcus/Aromatoleum strains are a major group of anaerobic benzoate degraders, and the transcriptional regulation of the bzd genes was extensively studied in...

  • Article
  • Open Access
52 Citations
6,172 Views
22 Pages

The objectives of this study were to evaluate the plant growth promoting effects on Arabidopsis by Pseudomonas sp. strains associated with rhizosphere of crop plants grown in Mekong Delta, Vietnam. Out of all the screened isolates, Pseudomonas PS01 i...

  • Article
  • Open Access
2,157 Views
19 Pages

22 March 2024

People living alone encounter well-being challenges due to unnoticed personal situations. Thus, it is essential to monitor their activities and encourage them to adopt healthy lifestyle habits without imposing a mental burden, aiming to enhance their...

  • Article
  • Open Access
3 Citations
2,886 Views
15 Pages

11 September 2023

Clonal plantation involves the rooting of cuttings from superior genotypes selected for their hybrid vigor and desired qualities. However, the cuttings of some Eucalyptus species and their hybrid genotypes present difficulties in their rooting capaci...

  • Article
  • Open Access
2 Citations
2,299 Views
18 Pages

Chromatin architecture is critical for the temporal and tissue-specific activation of genes that determine eukaryotic development. The functional interaction between enhancers and promoters is controlled by insulators and tethering elements that supp...

  • Article
  • Open Access
9 Citations
3,057 Views
20 Pages

4 January 2022

Phyllobacterium brassicacearum STM196, a plant growth-promoting rhizobacterium isolated from roots of oilseed rape, stimulates Arabidopsis growth. We have previously shown that the NRT2.5 and NRT2.6 genes are required for this growth promotion respon...

  • Article
  • Open Access
7 Citations
4,782 Views
17 Pages

Variations in flowering time and plant architecture have a crucial impact on crop biomass and yield, as well as the aesthetic value of ornamental plants. Aechmea fasciata, a member of the Bromeliaceae family, is a bromeliad variety that is commonly c...

  • Article
  • Open Access
1 Citations
3,107 Views
22 Pages

The subject of the research is the attractive Kościelna Street connecting two prestigious districts of the city of Poznań (Jeżyce and Sołacz). The oval ring layout of the street with its characteristic green separation strip sets the tone for the ent...

  • Article
  • Open Access
16 Citations
6,181 Views
30 Pages

Choice Architecture Cueing to Healthier Dietary Choices and Physical Activity at the Workplace: Implementation and Feasibility Evaluation

  • Eeva Rantala,
  • Saara Vanhatalo,
  • Tanja Tilles-Tirkkonen,
  • Markus Kanerva,
  • Pelle Guldborg Hansen,
  • Marjukka Kolehmainen,
  • Reija Männikkö,
  • Jaana Lindström,
  • Jussi Pihlajamäki and
  • Pilvikki Absetz
  • + 2 authors

14 October 2021

Redesigning choice environments appears a promising approach to encourage healthier eating and physical activity, but little evidence exists of the feasibility of this approach in real-world settings. The aim of this paper is to portray the implement...

  • Article
  • Open Access
10 Citations
3,514 Views
18 Pages

Definition of the Binding Architecture to a Target Promoter of HP1043, the Essential Master Regulator of Helicobacter pylori

  • Annamaria Zannoni,
  • Simone Pelliciari,
  • Francesco Musiani,
  • Federica Chiappori,
  • Davide Roncarati and
  • Vincenzo Scarlato

HP1043 is an essential orphan response regulator of Helicobacter pylori orchestrating multiple crucial cellular processes. Classified as a member of the OmpR/PhoB family of two-component systems, HP1043 exhibits a highly degenerate receiver domain an...

  • Article
  • Open Access
7 Citations
4,150 Views
26 Pages

Sensory Appeal and Routines Beat Health Messages and Visibility Enhancements: Mixed-Methods Analysis of a Choice-Architecture Intervention in a Workplace Cafeteria

  • Eeva Rantala,
  • Elina Järvelä-Reijonen,
  • Kati Pettersson,
  • Janne Laine,
  • Paula Vartiainen,
  • Johanna Närväinen,
  • Jussi Pihlajamäki,
  • Kaisa Poutanen,
  • Pilvikki Absetz and
  • Leila Karhunen

10 September 2022

Easier recognition and enhanced visibility of healthy options supposedly increase healthy choices, but real-world evidence remains scarce. Addressing this knowledge gap, we promoted nutritionally favourable foods in a workplace cafeteria with three c...

  • Article
  • Open Access
9 Citations
3,819 Views
25 Pages

Integrated Service Architecture to Promote the Circular Economy in Agriculture 4.0

  • Walter Augusto Varella,
  • Geraldo Cardoso de Oliveira Neto,
  • Eduardo Stefani,
  • Ivanir Costa,
  • Rogério Carlos Monteiro,
  • Wilians Conde,
  • Wanderley da Silva Junior,
  • Rolney Carlos Baptestone,
  • Roberto de Souza Goes and
  • Fellipe Silva Martins
  • + 6 authors

20 March 2024

Innovation has been the transforming tool of precision agriculture as a response to population growth and the demand for more food with quality, less waste, food security, and sustainable management of environmental resources. The challenges are to i...

  • Article
  • Open Access
4 Citations
3,697 Views
37 Pages

26 May 2023

The practice of promoting an image of the city using architectural objects, and the need to identify or create architectural icons in urban spaces, outlined in this article, occurs in many cities worldwide. The city of Szczecin in Poland, the subject...

  • Systematic Review
  • Open Access
4 Citations
7,280 Views
35 Pages

The Architectural Design Strategies That Promote Attention to Foster Mindfulness: A Systematic Review, Content Analysis and Meta-Analysis

  • Chaniporn Thampanichwat,
  • Tarid Wongvorachan,
  • Suphat Bunyarittikit,
  • Pornteera Chunhajinda,
  • Prima Phaibulputhipong and
  • Rungroj Wongmahasiri

14 August 2024

Attention is a pivotal component and a central vehicle of mindfulness, a psychological factor improving mental health. Despite architecture’s potential to encourage attention and mindfulness, there is still a research gap. This study aimed to i...

  • Review
  • Open Access
47 Citations
31,092 Views
34 Pages

Influence of Food and Beverage Companies on Retailer Marketing Strategies and Consumer Behavior

  • Amelie A. Hecht,
  • Crystal L. Perez,
  • Michele Polascek,
  • Anne N. Thorndike,
  • Rebecca L. Franckle and
  • Alyssa J. Moran

The retail food environment plays an important role in shaping dietary habits that contribute to obesity and other chronic diseases. Food and beverage manufacturers use trade promotion—incentives paid to retailers—to influence how product...

  • Article
  • Open Access
7 Citations
3,501 Views
26 Pages

Architecture-Promoted Biomechanical Performance-Tuning of Tissue-Engineered Constructs for Biological Intervertebral Disc Replacement

  • Gernot Lang,
  • Katja Obri,
  • Babak Saravi,
  • Aldo R. Boccaccini,
  • Anton Früh,
  • Michael Seidenstücker,
  • Bodo Kurz,
  • Hagen Schmal and
  • Bernd Rolauffs

20 May 2021

Background: Biological approaches to intervertebral disc (IVD) restoration and/or regeneration have become of increasing interest. However, the IVD comprises a viscoelastic system whose biological replacement remains challenging. The present study so...

  • Article
  • Open Access
589 Views
16 Pages

18 November 2025

Generative Artificial Intelligence (GenAI) is transforming higher education, yet concerns remain about its ethical use. The perceptions of students about GenAI may differ depending on the university degree in which they are enrolled. Thus, field-spec...

  • Article
  • Open Access
26 Citations
5,930 Views
20 Pages

Promoting Influenza Vaccination among Staff of Nursing Homes According to Behavioral Insights: Analyzing the Choice Architecture during a Nudge-Based Intervention

  • Chiara Lorini,
  • Francesca Ierardi,
  • Claudia Gatteschi,
  • Giacomo Galletti,
  • Francesca Collini,
  • Laura Peracca,
  • Patrizio Zanobini,
  • Fabrizio Gemmi and
  • Guglielmo Bonaccorsi

12 October 2020

(1) Background: Influenza vaccination uptake in nursing home (NH) workers is uncommon. The aim of this study was to understand the choice architecture of influenza vaccination acceptance or refusal among them and to promote vaccination acceptance usi...

  • Article
  • Open Access
12 Citations
5,159 Views
27 Pages

Plant Growth Promotion and Heat Stress Amelioration in Arabidopsis Inoculated with Paraburkholderia phytofirmans PsJN Rhizobacteria Quantified with the GrowScreen-Agar II Phenotyping Platform

  • Allene Macabuhay,
  • Borjana Arsova,
  • Michelle Watt,
  • Kerstin A. Nagel,
  • Henning Lenz,
  • Alexander Putz,
  • Sascha Adels,
  • Mark Müller-Linow,
  • Jana Kelm and
  • Ute Roessner
  • + 3 authors

30 October 2022

High temperatures inhibit plant growth. A proposed strategy for improving plant productivity under elevated temperatures is the use of plant growth-promoting rhizobacteria (PGPR). While the effects of PGPR on plant shoots have been extensively explor...

  • Article
  • Open Access
7 Citations
5,455 Views
21 Pages

The Restorative Potential of Icelandic Nature

  • Harpa Lind Kristjánsdóttir,
  • Sigrún Sigurðardóttir and
  • Anna María Pálsdóttir

This study aimed to investigate if proposed restorative attributes according to attention restoration theory and supportive environment theory could be experienced and identified in Icelandic landscape and contribute to a restorative experience in na...

  • Article
  • Open Access
9 Citations
2,553 Views
17 Pages

7 April 2024

Soil salinization is one of the leading threats to global ecosystems, food security, and crop production. Plant growth-promoting rhizobacteria (PGPRs) are potential bioinoculants that offer an alternative eco-friendly agricultural approach to enhance...

  • Review
  • Open Access
3 Citations
5,521 Views
38 Pages

Reverse-ChIP Techniques for Identifying Locus-Specific Proteomes: A Key Tool in Unlocking the Cancer Regulome

  • Tim M. G. MacKenzie,
  • Rocío Cisneros,
  • Rajan D. Maynard and
  • Michael P. Snyder

14 July 2023

A phenotypic hallmark of cancer is aberrant transcriptional regulation. Transcriptional regulation is controlled by a complicated array of molecular factors, including the presence of transcription factors, the deposition of histone post-translationa...

  • Article
  • Open Access
3 Citations
2,173 Views
21 Pages

Good architectural space design can bring positive emotional stimulation and relaxation to users, but few studies have investigated the quantitative indicators in architectural space design and their impact on user emotions. This study takes the righ...

  • Review
  • Open Access
23 Citations
5,969 Views
21 Pages

2 February 2023

In higher eukaryotes, the regulation of developmental gene expression is determined by enhancers, which are often located at a large distance from the promoters they regulate. Therefore, the architecture of chromosomes and the mechanisms that determi...

  • Article
  • Open Access
9 Citations
3,217 Views
18 Pages

14 December 2021

This paper investigates the effect of different Internet application scenarios on the forward and reverse knowledge transfer between architecture enterprises and component enterprises in the context of modular production in manufacturing enterprises....

  • Perspective
  • Open Access
18 Citations
13,075 Views
29 Pages

Architectural Multispecies Building Design: Concepts, Challenges, and Design Process

  • Yasha J. Grobman,
  • Wolfgang Weisser,
  • Assaf Shwartz,
  • Ferdinand Ludwig,
  • Roy Kozlovsky,
  • Avigail Ferdman,
  • Katia Perini,
  • Thomas E. Hauck,
  • Surayyn Uthaya Selvan and
  • Laura Windorfer
  • + 3 authors

31 October 2023

This perspective paper explores the concept of multispecies design in architecture, focusing on the building scale. Historically, architects have prioritized human needs, neglecting nature’s integration in urban settings, leading to environment...

  • Review
  • Open Access
34 Citations
6,830 Views
14 Pages

8 January 2023

Due to their sessile nature, plants have developed the ability to adapt their architecture in response to their environment. Branching is an integral component of plant architecture, where hormonal signals tightly regulate bud outgrowth. Strigolacton...

  • Article
  • Open Access
2 Citations
2,341 Views
29 Pages

Rapid advances in technology have led to an increasing demand for this type of information in the field of cultural heritage and architectural conservation. The article aims to use digital technology to obtain, record, store, and display accurate and...

  • Article
  • Open Access
4 Citations
1,979 Views
12 Pages

20 December 2023

The design of efficient oxygen evolution reaction (OER) electrocatalysts is of great significance for improving the energy efficiency of water electrolysis for hydrogen production. In this work, low-temperature fluorination and the introduction of a...

  • Review
  • Open Access
62 Citations
11,239 Views
17 Pages

Green Buildings: Human-Centered and Energy Efficiency Optimization Strategies

  • Hirou Karimi,
  • Mohammad Anvar Adibhesami,
  • Hassan Bazazzadeh and
  • Sahar Movafagh

25 April 2023

The rapid growth of the global population and urbanization has led to environmental degradation, resulting in a worldwide energy crisis. In response, the quality of architecture has evolved to prioritize energy efficiency, impacting indoor human heal...

  • Article
  • Open Access
4 Citations
2,996 Views
21 Pages

A Bidirectional Non-Coding RNA Promoter Mediates Long-Range Gene Expression Regulation

  • Carlos Alberto Peralta-Alvarez,
  • Hober Nelson Núñez-Martínez,
  • Ángel Josué Cerecedo-Castillo,
  • Augusto César Poot-Hernández,
  • Gustavo Tapia-Urzúa,
  • Sylvia Garza-Manero,
  • Georgina Guerrero and
  • Félix Recillas-Targa

25 April 2024

Recent evidence suggests that human gene promoters display gene expression regulatory mechanisms beyond the typical single gene local transcription modulation. In mammalian genomes, genes with an associated bidirectional promoter are abundant; bidire...

  • Systematic Review
  • Open Access
6 Citations
7,810 Views
20 Pages

A Systematic Review of Architecture Stimulating Attention through the Six Senses of Humans

  • Chaniporn Thampanichwat,
  • Pratsanee Meksrisawat,
  • Narongrit Jinjantarawong,
  • Somchok Sinnugool,
  • Prima Phaibulputhipong,
  • Pornteera Chunhajinda and
  • Bhumin Bhutdhakomut

25 July 2024

The climate change crisis is negatively impacting the mental health of people worldwide. Attention is a pivotal pathway to healing ourselves and the world, as it is a sensory process that enhances mental health and promotes sustainable behavior. Desp...

  • Article
  • Open Access
18 Citations
4,186 Views
32 Pages

Integrating Sustainable Manufacturing into Architectural Design Teaching through Architectural Design Competitions

  • Lin Li,
  • Xiaolong Yang,
  • Xingwei Xiang,
  • Luyi Kong,
  • Jiner Dai and
  • Qingyong Zeng

13 April 2023

Sustainable manufacturing is essential for boosting resource allocation efficiency, as well as sustainable economic development, while the construction industry is one of the main sectors affecting it. However, the complexity of multidisciplinary int...

  • Article
  • Open Access
1 Citations
6,921 Views
23 Pages

21 November 2022

With the applications of new construction technologies and design ideas, innovative construction methods and architectural designs promote overall productivity and enrich architectural impressions. However, faced with the contradictions between const...

  • Article
  • Open Access
15 Citations
3,934 Views
10 Pages

PromoterLCNN: A Light CNN-Based Promoter Prediction and Classification Model

  • Daryl Hernández,
  • Nicolás Jara,
  • Mauricio Araya,
  • Roberto E. Durán and
  • Carlos Buil-Aranda

23 June 2022

Promoter identification is a fundamental step in understanding bacterial gene regulation mechanisms. However, accurate and fast classification of bacterial promoters continues to be challenging. New methods based on deep convolutional networks have b...

  • Article
  • Open Access
20 Citations
4,718 Views
28 Pages

25 July 2021

Cittaslow International promotes harmonious development of small towns based on sustainable relationships between economic growth, protection of local traditions, cultural heritage and the environment, and an improvement in the quality of local life....

  • Article
  • Open Access
1 Citations
3,230 Views
10 Pages

Background: Lack of physical activity (PA) is the fourth risk factor for all-cause mortality. Regular PA reduces noncommunicable disease (NCD) and mortality risk. The built environment (BE) is a determinant of spontaneous daily PA. Professionals who...

  • Article
  • Open Access
6 Citations
3,474 Views
13 Pages

9 September 2023

The spontaneous evolution of vernacular architecture mainly relies on the inheritance of architectural traditions and the innovative decisions of occupants, rather than the professional guidance of architects and the promotion of government agencies....

  • Article
  • Open Access
6 Citations
3,454 Views
23 Pages

14 April 2025

Architectural heritage structures stand out as important local elements in rural tourism activities carried out in rural areas to observe and experience natural and cultural values, local activities, and rural life culture. The protection and reuse o...

  • Article
  • Open Access
1 Citations
3,197 Views
20 Pages

In the image era, architectural drawing gradually evolved from being a part of traditional architectural design to an artistic form with independent aesthetic value. However, a systematic evaluation method for this unique art form is still lacking. T...

  • Article
  • Open Access
29 Citations
12,700 Views
14 Pages

17 August 2017

The contributions of sustainability to architectural designs are steadily increasing in parallel with developments in technology. Although sustainability seems to be a new concept in today’s architecture, in reality, it is not. This is because, much...

  • Article
  • Open Access
2 Citations
2,636 Views
20 Pages

16 September 2025

Applying embodied cognition theory is essential for the conservation and revitalization of architectural heritage. This paper examines how embodied cognition, architectural design, and local historical resources impact the conservation and revitaliza...

  • Article
  • Open Access
1,025 Views
17 Pages

17 June 2025

This research explores a studio experience conducted at the Department of Architecture, Gebze Technical University, focusing on the integration of tectonic housing concepts into architectural design education. The study adopts a comprehensive methodo...

  • Article
  • Open Access
1 Citations
8,263 Views
27 Pages

27 October 2022

Korea tried to reconstruct its tradition as a modern nation and promote nationalism only in the 1960s, a relatively late period compared to the West. So-called “tradition-making” began by promoting the full-fledged national shrine project...

  • Article
  • Open Access
1 Citations
2,118 Views
17 Pages

22 December 2024

As sustainable architecture is increasingly emphasizing material reuse, this study proposes a novel, interactive workflow that integrates robotic arms and artificial intelligence to transform waste materials from architectural models into creative de...

  • Article
  • Open Access
19 Citations
3,094 Views
16 Pages

Propagating architectural heritage is of great significance to the inheritance and protection of local culture. Recommendations based on user preferences can greatly benefit the promotion of local architectural heritage so as to better protect and in...

  • Article
  • Open Access
7 Citations
4,889 Views
23 Pages

17 October 2022

The COVID-19 pandemic and the death of George Floyd shed new light on longstanding disparities that exist in low-income communities of color and impact their overall well-being. Architectural educators and practitioners across the United States are e...

  • Article
  • Open Access
3,997 Views
26 Pages

A Systematic Review of Architectural Atmosphere That Fosters Mindfulness Constructs

  • Chaniporn Thampanichwat,
  • Limpasilp Sirisakdi,
  • Sippakorn Petsirasan,
  • Duangkamon Wutisun,
  • Sathirat Singkham,
  • Tarid Wongvorachan,
  • Prima Phaibulputhipong,
  • Suphat Bunyarittikit and
  • Rungroj Wongmahasiri

11 July 2025

This study explores how architectural atmosphere can foster mindfulness constructs in response to the growing mental health crisis. Mindfulness, known for improving mental health, reducing stress, and enhancing overall well-being, is increasingly rec...

  • Article
  • Open Access
26 Citations
7,069 Views
17 Pages

Perspectives for the Development of Sustainable Cultural Tourism

  • Georgiana Daniela Stoica,
  • Violeta-Andreea Andreiana,
  • Mircea Constantin Duica,
  • Maria-Cristina Stefan,
  • Irina Olimpia Susanu,
  • Mihaela Denisa Coman and
  • Dorin Iancu

The study involves a comparative analysis of cultural tourism in Bucharest and Paris to identify the main aspects of sustainable cultural tourism. A set of six characteristics (civil monuments and architectural assemblies, religious monuments and arc...

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