708 Results Found

L-theanine, a non-protein amino acid naturally occurring in tea leaves, is recognized for its antioxidant, anti-inflammatory, and neuroprotective properties. Despite its known benefits, the mechanisms by which L-theanine influences lifespan extension...

Selected technological solutions can impact health status of animals. The aim of this case study was to determine the effect of different housing systems on disease prevalence and the productive lifespan of dairy cows. In total, 480 cows kept indoors...

Agricultural activities have been positively affected by the use of plastic products, but this has resulted in the production of plastic waste and led to an increase in environmental pollution. To continue benefiting from the use of plastics but addr...

Mammary glands in cows are highly dynamic, making genomic stability particularly crucial. Continuous lactation and self-renewal of these glands are primary contributors to genomic instability. Results: We employed transcriptomic and proteomic methods...

Slowing down replacement cycles to reduce resource depletion and prevent waste generation is a promising path toward a circular economy (CE). However, an obligation to longevity only sometimes makes sense. It could sometimes even backfire if one focu...

The third largest angiosperm family, Leguminosae, displays a broad range of reproductive strategies and has an exceptional practical value. Whereas annual legume species are mostly planted as crops, there is a significant interest in breeding and cul...

This study investigated cow longevity, culling reasons, and risk factors influencing culling in South African Holstein and Jersey dairy herds. Lactation records of 1,150,625 Jersey and 1,534,875 Holstein cows from 1864 herds, recorded through the Nat...

The ability of dairy farmers to keep their cows for longer could positively enhance the economic performance of farms, reduce the environmental footprint of the milk industry, and provide overall help in justifying a sustainable use of animals for fo...

The ability of dairy farmers to keep their cows for longer could positively enhance the economic performance of the farms, reduce the environmental footprint of the milk industry, and overall help in justifying a sustainable use of animals for food p...

This study aimed to propose novel longevity indicators by comparing genetic parameters for traditional (TL; i.e., the cow’s lifespan after the first calving) and functional (FL; i.e., how long the cow stayed in the herd while also calving; assu...

Two Peruvian strains of the genus Brachionus were isolated from impacted coastal wetlands. With an integrative taxonomic view, we described their taxonomic status, morphological characters, productive parameters, and phylogenetic position. In the cas...

Global textile production and consumption has increased steadily over the past 15 years, which has caused significant impacts on the climate and the environment. In 2022, the EU launched a strategy for sustainable and circular textiles, stating that...

A pattern of natural killer cell (NK cell) heterogeneity determines proliferative and functional responses to activating stimuli in individuals. Obtaining the progeny of a single cell by cloning the original population is one of the ways to study NK...

To provide a theoretical basis for biogenic fly-killing pesticides, in this study, we sought to examine the lethal effects of Lepista nuda mycelium-supplemented diets in Drosophila melanogaster. In doing so, we also studied the effects of Lepista nud...

Increasing the use of each product, most often called longer lifespans, is an effective environmental strategy. This article discusses how garment lifespans can be described in order to be measured and compared. It answers two sub-questions: (1) what...

Improving product sustainability is becoming an increasingly significant challenge for modern enterprises. A growing number of manufacturers are interested in enhancing product sustainability throughout the product life cycle. This study is concerned...

Mating in female Drosophila melanogaster causes midgut hypertrophy and reduced lifespan, and these effects are blocked by the drug mifepristone. Eip75B is a transcription factor previously reported to have pleiotropic effects on Drosophila lifespan....

Our desire to live longer has led to an ever-increasing number of novel antiaging products. However, few molecules have any real effect and new ones need to be studied before they can be used commercially. In this contribution, activation of the calo...

To refine the fatigue lifespan of products such as automobiles, refrigerators, etc., parametric accelerated life testing (ALT), as a new method for ensuring structured reliability, put forward to assess designs by subjecting them to repeated loads. T...

Background: Sodium benzoate (SB) is widely used in food products, cosmetics, and medical solutions due to its antimicrobial properties. While it is generally considered safe and has potential neuroprotective benefits, SB has also been linked to adver...

Telomere length (TL) has gained attention as a biomarker for longevity and productivity in dairy cattle. This study explored the association between neonatal TL in Holstein calves and lifetime parameters (lifespan, milk production, and reproduction)....

Epigallocatechin-3-gallate (EGCG) is the most abundant polyphenol in green tea. Our previous report showed that induced hormesis was a critical determinant for the promotion of a healthy lifespan in Caenorhabditis elegans. In the present study, we in...

Human microbiota is heavily involved in host health, including the aging process. Based on the hypothesis that the human microbiota manipulates host aging via the production of chemical messengers, lifespan-extending activities of the metabolites pro...

While the doubling of life expectancy in developed countries during the 20th century can be attributed mostly to decreases in child mortality, the trillions of dollars spent on biomedical research by governments, foundations and corporations over the...

This study investigates the effects of salinity, temperature, and diet on the biological characteristics of the rotifer Brachionus plicatilis, an essential live feed in aquaculture. The results indicate that environmental factors have a significant i...

Reactive oxygen species (ROS) and free radicals work to maintain homeostasis in the body, but their excessive production causes damage to the organism. The human body is composed of a variety of cells totaling over 60 trillion cells. Each cell perfor...

Background: With the development of an aging sociality, aging-related diseases, such as Alzheimer’s disease, cardiovascular disease, and diabetes, are dramatically increasing. To find small molecules from natural products that can prevent the a...

Enhanced oxidative stress is closely related to aging and impaired metabolic health and is influenced by diet-derived nutrients and energy. Recent studies have shown that methionine restriction (MetR) is related to longevity and metabolic health in o...

Design for longevity is known as an eco-design opportunity and could help to reduce the environmental footprint of energy-free items. However, extending the lifespan of products is not always desirable and the focus should be on achieving an optimal...

This study investigates the impact of ozone exposure on the hardness of synthetic rubber specimens (a blend of NR (natural rubber) and CR (chloroprene rubber)) through accelerated aging tests. Using a linear regression model, the research predicts th...

Background: CDK 4/6 inhibitors (CDK4/6is) are the first-line treatment for metastatic luminal-like breast cancer (BC). These drugs induce macrocytosis without anemia in most patients. The mechanism for the red blood cell (RBC) changes is unknown. In...

Aging is a natural phenomenon that occurs in all living organisms. In humans, aging is associated with lowered overall functioning and increased mortality out of the risk for various age-related diseases. Hence, researchers are pushed to find effecti...

Improvement of longevity is an eternal dream of human beings. The accumulation of protein damages is considered as a major cause of aging. Here, we report that the injection of exogenous recombinant mouse serum albumin (rMSA) reduced the total damage...

Queen bee larva (QBL) is one kind of important edible insect that is harvested during royal jelly production process. QBL has many physiological functions; however, limited information is available regarding its antiaging effects. In this study, the...

Many reports have shown that grains play an important role in our daily lives and can provide energy and nutrients to protect us from various diseases, and they are considered to be indispensable parts of our lives. It has been reported that some con...

Thermal barrier coating (TBC) systems have presented an ongoing design issue in bids to improve the lifespan of coatings. A TBC can support an extended lifespan by repairing cracks between interfacial layers during high thermal exposure while at the...

Olive mill wastewater is an important agro-industrial waste with no established treatment method. The authors have developed a phenol separation method that could potentially cover the treatment cost of the waste. The purpose of this study was to ide...

Food is a crucial component affecting the health of individuals, which may have the potential to expand lifespan. It has been shown that a long lifespan may be related to fine-tuned autophagy. In general, suitable autophagy could play a significant r...

The maintenance of cellular homeostasis over time is essential to avoid the degeneration of biological systems leading to aging and disease. Several interconnected pathways are active in this kind of quality control. One of them is autophagy, the vac...

Proline is a pivotal and multifunctional amino acid that is used not only as a nitrogen source but also as a stress protectant and energy source. Therefore, proline metabolism is known to be important in maintaining cellular homeostasis. Here, we dis...

Background/Objective: Aging is a significant risk factor for chronic diseases and disability, yet effective anti-aging interventions remain elusive. We explored the potential of 3-hydroxybutyrate (3HB), an endogenous metabolite with established safet...

Background: Intestinal aging is characterized by declining protein homeostasis via reduced proteasome activity, which are hallmarks of age-related diseases. Our previous study showed that caffeine intake improved intestinal integrity with age by redu...

Animals often regulate their nutrient intake according to their physiological needs. There is evidence that different traits require specific nutrient blends, and that animals cannot always maximize all traits with a single diet (“nutritional t...

This study specifically examines the post-reproductive lifespan and ovarian activation in honeybee workers (Apis mellifera) with differing life expectancies. Drawing on the “grandmother hypothesis”, which postulates that older females enh...

Rubberized asphalt mixtures, including dry-process, wet-process with asphalt rubber binder, and wet-process with terminal blend binder, are superior options for pavement construction compared to conventional hot mix asphalt (HMA). This study compared...

Multiple ovulations and so multiple pregnancies have increased recently in dairy cattle. The incidence of the double ovulation impact in high producers at insemination may be over 20%. Twin pregnancies are undesirable as they seriously compromise the...

Recent advancements in science and technology have resulted in products with enhanced reliability and extended lifespans across the aerospace and related sectors. Traditional statistical models struggle to assess their reliability accurately, prompti...

This study developed inventive and repurposable children’s furniture to improve functionality and extend product lifespan. Unlike typical cribs which serve a single purpose, the proposed design supports multiple functions: crib, cushioned chair...

The earlier planning methods of supply chains (SC) in the skeleton of the extended material requirements planning (EMRP), where the time horizon of the reverse Laplace is infinite, were not convenient to estimate the impact of the technical obsolesce...

The Enhanced Geothermal System (EGS) constructs an artificial thermal reservoir by hydraulic fracturing to extract heat economically from hot dry rock. As the core element of the EGS heat recovery process, mass and heat transfer of working fluid main...