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3,117 Results Found

  • Review
  • Open Access
13 Citations
5,066 Views
14 Pages

Immunonutrition in Orthopedic and Traumatic Patients

  • Pietro Gregori,
  • Edoardo Franceschetti,
  • Susanna Basciani,
  • Lorenzo Impieri,
  • Biagio Zampogna,
  • Alfredo Matano,
  • Carlo Manzi,
  • Ludovico Carbone,
  • Luigi Marano and
  • Rocco Papalia

19 January 2023

The role of nutrition intervention in surgical settings is constantly developing and evolving. Immunonutrition represents a viable option to reduce perioperative and postoperative complications in surgical oncology. However, as far as we know, little...

  • Systematic Review
  • Open Access
2 Citations
4,043 Views
11 Pages

Caesarean Section for Orthopedic Indications

  • Maciej Ziętek,
  • Paweł Ziętek,
  • Daniel Kotrych and
  • Małgorzata Szczuko

27 November 2023

Background: The increasing number of late complications described after cesarean sections is prompting a reexamination of the indications for them in pregnant women. The high percentage of pregnancies terminated by preventive cesarean section for non...

  • Review
  • Open Access
1 Citations
6,886 Views
20 Pages

Orthopedic Manifestations of Syringomyelia: A Comprehensive Review

  • Mohamad Fadila,
  • Geva Sarrabia,
  • Shay Shapira,
  • Eyal Yaacobi,
  • Yuval Baruch,
  • Itzhak Engel and
  • Nissim Ohana

Background: Syringomyelia is a complex neurological disorder characterized by a fluid-filled cavity (syrinx) within the spinal cord, frequently resulting from altered cerebrospinal fluid (CSF) dynamics. While its clinical manifestations are diverse,...

  • Review
  • Open Access
35 Citations
14,934 Views
13 Pages

Multimodal Pain Management in Orthopedic Surgery

  • Aparna Chunduri and
  • Amit Kumar Aggarwal

28 October 2022

Background: Orthopedic surgery typically results in moderate to severe pain in a majority of patients. Opioids were traditionally the primary medication to target mechanisms of pain transmission. Multimodal analgesia has become a preferred method of...

  • Article
  • Open Access
1,002 Views
21 Pages

Background/Objectives: Due to the aging population, orthopedics has become the surgical field with the fastest and greatest growth, and health systems must therefore ensure the sustainable development of this field. The objective of this study is to...

  • Review
  • Open Access
1 Citations
4,064 Views
16 Pages

Combination Antibiotic Therapy for Orthopedic Infections

  • Eric Bonnet and
  • Julie Lourtet-Hascoët

Background/Objectives: Limited robust data support the use of antibiotic combinations in the treatment of orthopedic infections. However, in certain situations, the combination of antibiotics seems to be beneficial. This review aims to outline the ci...

  • Systematic Review
  • Open Access
1,134 Views
12 Pages

A Scoping Review of CERAMENT™ Applications in Orthopedic Surgery

  • Antonio Bove,
  • Adriano Braile,
  • Sabrina Sirico,
  • Nicola Orabona and
  • Mariantonia Braile

22 October 2025

Background: Bone defects resulting from trauma, infection, or benign tumors pose major challenges in orthopedic surgery. Traditional approaches, such as autologous bone grafting, are limited by donor site morbidity and graft availability. CERAMENT&tr...

  • Article
  • Open Access
4 Citations
2,735 Views
13 Pages

19 June 2024

It is estimated that globally medical surgical specialties, including orthopedics, produce large amounts of hospital waste. However, the possibilities of recycling materials are not well highlighted. Orthopedic hospitals can collect larger volumes of...

  • Review
  • Open Access
4 Citations
4,681 Views
23 Pages

Viscoelastic Hemostatic Assays for Orthopedic Trauma and Elective Procedures

  • Christiaan N. Mamczak,
  • Jacob Speybroeck,
  • John E. Stillson,
  • Joseph Dynako,
  • Andres Piscoya,
  • Ethan E. Peck,
  • Michael Aboukhaled,
  • Emily Cancel,
  • Michael McDonald and
  • Matthew E. Kutcher
  • + 3 authors

12 July 2022

The application of viscoelastic hemostatic assays (VHAs) (e.g., thromboelastography (TEG) and rotational thromboelastometry (ROTEM)) in orthopedics is in its relative infancy when compared with other surgical fields. Fortunately, several recent studi...

  • Article
  • Open Access
6 Citations
1,818 Views
17 Pages

13 November 2024

Inside hospitals, there is a trend of increasing levels of air pollutants. However, only the indoor air quality in operating theaters is carefully monitored. Therefore, we set the goal of this study to evaluate the indoor air quality in areas of an o...

  • Review
  • Open Access
1,224 Views
11 Pages

Perioperative Methadone in Orthopedic Surgery: A Scoping Review

  • Albert F. Yang,
  • Emily Lee,
  • Mahsa Babaei and
  • Paul Lee

25 September 2025

Background/Objective: The present study is a scoping review of the literature from Medline, PubMed, and Scopus databases from 2000 to 2025. Studies were selected based on predefined criteria, including the intraoperative administration of methadone d...

  • Review
  • Open Access
10 Citations
5,370 Views
27 Pages

Nanomaterials for Anti-Infection in Orthopedic Implants: A Review

  • Junhao Sui,
  • Yijin Hou,
  • Mengchen Chen,
  • Zhong Zheng,
  • Xiangyu Meng,
  • Lu Liu,
  • Shicheng Huo,
  • Shu Liu and
  • Hao Zhang

21 February 2024

Postoperative implant infection is a severe complication in orthopedic surgery, often leading to implant failure. Current treatment strategies mainly rely on systemic antibiotic therapies, despite contributing to increasing bacterial resistance. In r...

  • Review
  • Open Access
3 Citations
8,482 Views
11 Pages

7 November 2024

The utilization of recombinant human growth hormone therapy in pediatric populations, originally approved to treat diseases of growth hormone deficiency, has expanded to encompass a broader range of indications, leading to a threefold increase in its...

  • Communication
  • Open Access
14 Citations
6,547 Views
10 Pages

Mapping Bacterial Biofilm on Features of Orthopedic Implants In Vitro

  • Kelly Moore,
  • Niraj Gupta,
  • Tripti Thapa Gupta,
  • Khushi Patel,
  • Jacob R. Brooks,
  • Anne Sullivan,
  • Alan S. Litsky and
  • Paul Stoodley

Implant-associated infection is a major complication of orthopedic surgery. One of the most common organisms identified in periprosthetic joint infections is Staphylococcus aureus, a biofilm-forming pathogen. Orthopedic implants are composed of a var...

  • Article
  • Open Access
1,142 Views
17 Pages

Determinants of Scientific Article Publication Among Peruvian Physicians and Orthopedic Residents

  • Rodrigo Alejandro-Salinas,
  • Diego A. Maticorena-Quevedo,
  • Alfonso Barnechea-Rey,
  • Percy Herrera-Añazco and
  • Vicente A. Benites-Zapata

Background: Orthopedic scientific publications play an important role worldwide. Because of the limited evidence in the Latin American literature, we aimed to evaluate the determinants of scientific publication among Peruvian orthopedics as an approa...

  • Review
  • Open Access
2 Citations
2,129 Views
32 Pages

The Categorization of Perinatal Derivatives for Orthopedic Applications

  • Amol H. Trivedi,
  • Vicki Z. Wang,
  • Edward J. McClain,
  • Praveer S. Vyas,
  • Isaac R. Swink,
  • Edward D. Snell,
  • Boyle C. Cheng and
  • Patrick J. DeMeo

Musculoskeletal (MSK) pathology encompasses an array of conditions that can cause anything from mild discomfort to permanent injury. Their prevalence and impact on disability have sparked interest in more effective treatments, particularly within ort...

  • Article
  • Open Access
3 Citations
2,421 Views
19 Pages

22 November 2021

The main purpose of the article is to describe the methodology used for multi-criteria optimization of the geometric features of the orthopedic implant used for the reconstruction of the anterior cruciate ligament located in the knee joint. The metho...

  • Review
  • Open Access
60 Citations
12,671 Views
12 Pages

Biomaterials in Orthopedic Devices: Current Issues and Future Perspectives

  • Nina Filip,
  • Iulian Radu,
  • Bogdan Veliceasa,
  • Cristiana Filip,
  • Mihaela Pertea,
  • Andreea Clim,
  • Alin Constantin Pinzariu,
  • Ilie Cristian Drochioi,
  • Remus Lucian Hilitanu and
  • Ionela Lacramioara Serban

14 October 2022

In orthopedics, bone fixation imposes the use of implants in almost all cases. Over time, the materials used for the implant have evolved from inert materials to those that mimic the morphology of the bone. Therefore, bioabsorbable, biocompatible, an...

  • Review
  • Open Access
15 Citations
3,971 Views
21 Pages

Metallic Antibacterial Surface Treatments of Dental and Orthopedic Materials

  • Rushui Bai,
  • Liying Peng,
  • Qiannan Sun,
  • Yunfan Zhang,
  • Lingyun Zhang,
  • Yan Wei and
  • Bing Han

15 October 2020

The oral cavity harbors complex microbial communities, which leads to biomaterial-associated infections (BAI) during dental and orthopedic treatments. Conventional antibiotic treatments have met great challenges recently due to the increasing emergen...

  • Article
  • Open Access
29 Citations
4,926 Views
20 Pages

Accurate knowledge of the prevalence and trends of orthopedic surgeries can facilitate the design of medical plans for effective treatments. The National Endoprosthetic Registry (NER) in Romania provides statistics on endoprosthetic activity (hip, kn...

  • Review
  • Open Access
33 Citations
8,915 Views
31 Pages

Antibacterial and Anti-Inflammatory Coating Materials for Orthopedic Implants: A Review

  • Gang Tan,
  • Jing Xu,
  • Walter Munesu Chirume,
  • Jieyu Zhang,
  • Hui Zhang and
  • Xuefeng Hu

18 November 2021

Orthopedic implant failure is the most common complication of orthopedic surgery, causing serious trauma and resulting in a tremendous economic burden for patients. There are many reasons for implant failure, among which peri-implant infection (or im...

  • Article
  • Open Access
11 Citations
4,344 Views
7 Pages

The Usefulness of the QR Code in Orthotic Applications after Orthopedic Surgery

  • Jaeho Cho,
  • Gi-Won Seo,
  • Jeong Seok Lee,
  • Hyung Ki Cho,
  • Eun Myeong Kang,
  • Jahyung Kim,
  • Dong-Il Chun,
  • Young Yi and
  • Sung Hun Won

The purpose of this study is to evaluate the utility of QR (quick response) codes in explaining the proper method for orthotic use after orthopedic surgery. A questionnaire survey was adopted to evaluate patient satisfaction with education and traini...

  • Review
  • Open Access
55 Citations
9,291 Views
22 Pages

Recent Developments in Coatings for Orthopedic Metallic Implants

  • Muzamil Hussain,
  • Syed Hasan Askari Rizvi,
  • Naseem Abbas,
  • Uzair Sajjad,
  • Muhammad Rizwan Shad,
  • Mohsin Ali Badshah and
  • Asif Iqbal Malik

30 June 2021

Titanium, stainless steel, and CoCrMo alloys are the most widely used biomaterials for orthopedic applications. The most common causes of orthopedic implant failure after implantation are infections, inflammatory response, least corrosion resistance,...

  • Review
  • Open Access
1 Citations
4,180 Views
19 Pages

Antimicrobials in Orthopedic Infections: Overview of Clinical Perspective and Microbial Resistance

  • Bogdan Huzum,
  • Ana Clara Aprotosoaie,
  • Ovidiu Alexa,
  • Paul Dan Sîrbu,
  • Bogdan Puha,
  • Bogdan Veliceasa and
  • Riana Maria Huzum

2 December 2024

Orthopedic infections are challenging pathologies that impose a heavy burden on patients and the healthcare system. Antimicrobial therapy is a critical component of the successful management of orthopedic infections, but its effectiveness depends on...

  • Review
  • Open Access
36 Citations
5,491 Views
14 Pages

Molecular Mechanism of Ferroptosis in Orthopedic Diseases

  • Lu Gao,
  • Weizhong Hua,
  • Lixiang Tian,
  • Xuchang Zhou,
  • Dongxue Wang,
  • Yajing Yang and
  • Guoxin Ni

24 September 2022

Ferroptosis is a new iron-dependent programmed cell death process that is directly mediated by the accumulation of lipid peroxides and reactive oxygen species. Numerous studies have shown that ferroptosis is important in regulating the occurrence and...

  • Article
  • Open Access
7 Citations
4,169 Views
15 Pages

Profit-Influencing Factors in Orthopedic Surgery: An Analysis of Costs and Reimbursements

  • Felix Rohrer,
  • Aresh Farokhnia,
  • Hubert Nötzli,
  • Frederik Haubitz,
  • Tanja Hermann,
  • Brigitta Gahl,
  • Andreas Limacher and
  • Jan Brügger

The aging population and the associated demand for orthopedic surgeries are increasing health costs. Although the Diagnostic Related Groups (DRG) system was introduced to offer incentives for hospitals, concerns remain that reimbursements for older a...

  • Proceeding Paper
  • Open Access
312 Views
18 Pages

Mechanical Behavior of Bioinspired Nanocomposites for Orthopedic Applications

  • Kalyani Pathak,
  • Simi Deka,
  • Elora Baruah,
  • Partha Protim Borthakur,
  • Rupam Deka and
  • Nayan Medhi

The application of bioinspired nanocomposites in orthopedic implants marks a significant innovation in biomedical engineering, aimed at overcoming long-standing limitations of conventional implant materials. Traditional implants frequently suffer fro...

  • Review
  • Open Access
16 Citations
8,911 Views
16 Pages

21 October 2013

Surgeries’ sterile conditions and perioperative antibiotic therapies decrease implant associated infections rates significantly. However, up to 10% of orthopedic devices still fail due to infections. An implant infection generates a high socio-econom...

  • Article
  • Open Access
3 Citations
2,463 Views
10 Pages

Postoperative Urinary Retention after Pediatric Orthopedic Surgery

  • Mohan V. Belthur,
  • Ian M. Singleton,
  • Jessica D. Burns,
  • M’hamed H. Temkit and
  • Thomas J. Sitzman

28 September 2022

Purpose: This study aims to describe the incidence of postoperative urinary retention among pediatric patients undergoing orthopedic surgery and identify risk factors. Methods: The Pediatric Health Information System was used to identify children age...

  • Review
  • Open Access
43 Citations
9,847 Views
17 Pages

Role of the Complement System in the Response to Orthopedic Biomaterials

  • Yvonne Mödinger,
  • Graciosa Q. Teixeira,
  • Cornelia Neidlinger-Wilke and
  • Anita Ignatius

27 October 2018

Various synthetic biomaterials are used to replace lost or damaged bone tissue that, more or less successfully, osseointegrate into the bone environment. Almost all biomaterials used in orthopedic medicine activate the host-immune system to a certain...

  • Systematic Review
  • Open Access
10 Citations
4,648 Views
9 Pages

The Orthopedic Effects of Electronic Cigarettes: A Systematic Review and Pediatric Case Series

  • Maxwell Luke Armstrong,
  • Nicholas Smith,
  • Rhiannon Tracey and
  • Heather Jackman

4 January 2022

Electronic cigarette (EC) use is highly prevalent, especially in the adolescent population, where 29% of Canadian adolescents have used an EC in the past thirty days per national surveys. Our pediatric orthopedic referral centre observed a cluster of...

  • Article
  • Open Access
21 Citations
7,397 Views
11 Pages

Phlebitis leads to increased discomfort for patients, longer hospital stays, and higher healthcare costs. This study aimed to identify predictive factors of peripheral phlebitis related to intravenous injection among orthopedic inpatients, develop a...

  • Article
  • Open Access
11 Citations
2,961 Views
15 Pages

15 June 2022

Background: Trajectory planning is the premise of the control of orthopedic robots, which is directly related to the safety of the human body. However, to date, the trajectory of orthopedic robots has been restricted to lines and spline curves. This...

  • Review
  • Open Access
4 Citations
3,848 Views
21 Pages

Artificial Intelligence in Orthopedic Medical Education: A Comprehensive Review of Emerging Technologies and Their Applications

  • Kyle Sporn,
  • Rahul Kumar,
  • Phani Paladugu,
  • Joshua Ong,
  • Tejas Sekhar,
  • Swapna Vaja,
  • Tamer Hage,
  • Ethan Waisberg,
  • Chirag Gowda and
  • Alireza Tavakkoli
  • + 1 author

Integrating artificial intelligence (AI) and mixed reality (MR) into orthopedic education has transformed learning. This review examines AI-powered platforms like Microsoft HoloLens, Apple Vision Pro, and HTC Vive Pro, which enhance anatomical visual...

  • Review
  • Open Access
168 Citations
15,961 Views
26 Pages

Additive Manufacturing of Customized Metallic Orthopedic Implants: Materials, Structures, and Surface Modifications

  • Long Bai,
  • Cheng Gong,
  • Xiaohong Chen,
  • Yuanxi Sun,
  • Junfang Zhang,
  • Lecai Cai,
  • Shengyan Zhu and
  • Sheng Quan Xie

12 September 2019

Metals have been used for orthopedic implants for a long time due to their excellent mechanical properties. With the rapid development of additive manufacturing (AM) technology, studying customized implants with complex microstructures for patients h...

  • Article
  • Open Access
1 Citations
2,232 Views
17 Pages

29 November 2023

The rapid and accurate detection of orthopedic medical devices is pivotal in enhancing health care delivery, particularly by improving workflow efficiency. Despite advancements in medical imaging technology, current detection models often fail to mee...

  • Article
  • Open Access
3 Citations
2,481 Views
11 Pages

22 November 2022

In recent decades, patient safety in orthopedics has gained increasing importance and has been regarded as a core concept of medical care quality. However, according to currently published studies, measurement instruments used to evaluate post-surger...

  • Review
  • Open Access
35 Citations
6,816 Views
14 Pages

11 January 2022

Since its development, deep learning has been quickly incorporated into the field of medicine and has had a profound impact. Since 2017, many studies applying deep learning-based diagnostics in the field of orthopedics have demonstrated outstanding p...

  • Review
  • Open Access
20 Citations
5,403 Views
19 Pages

Family Caregiver Strain and Challenges When Caring for Orthopedic Patients: A Systematic Review

  • Umile Giuseppe Longo,
  • Maria Matarese,
  • Valeria Arcangeli,
  • Viviana Alciati,
  • Vincenzo Candela,
  • Gabriella Facchinetti,
  • Anna Marchetti,
  • Maria Grazia De Marinis and
  • Vincenzo Denaro

Background: Caregivers represent the core of patients’ care in hospital structures, in the process of care and self-care after discharge. We aim to identify the factors that affect the strain of caring for orthopedic patients and how these fact...

  • Review
  • Open Access
3 Citations
3,708 Views
20 Pages

Compilation and Analysis of Web-Based Orthopedic Personalized Predictive Tools: A Scoping Review

  • Patrick Curtin,
  • Alexandra Conway,
  • Liu Martin,
  • Eugenia Lin,
  • Prakash Jayakumar and
  • Eric Swart

12 November 2020

Web-based personalized predictive tools in orthopedic surgery are becoming more widely available. Despite rising numbers of these tools, many orthopedic surgeons may not know what tools are available, how these tools were developed, and how they can...

  • Article
  • Open Access
2 Citations
2,009 Views
9 Pages

7 December 2023

Background: Orthopedic surgery is a specialty at risk for medical malpractice claims. We aimed to assess the frequency of alleged malpractice cases related to orthopedic surgery in the Netherlands from the last 15 years. Methods: We systematically se...

  • Review
  • Open Access
8 Citations
5,876 Views
21 Pages

Integrating Artificial Intelligence in Orthopedic Care: Advancements in Bone Care and Future Directions

  • Rahul Kumar,
  • Kyle Sporn,
  • Joshua Ong,
  • Ethan Waisberg,
  • Phani Paladugu,
  • Swapna Vaja,
  • Tamer Hage,
  • Tejas C. Sekhar,
  • Amar S. Vadhera and
  • Mouayad Masalkhi
  • + 2 authors

Artificial intelligence (AI) is revolutionizing the field of orthopedic bioengineering by increasing diagnostic accuracy and surgical precision and improving patient outcomes. This review highlights using AI for orthopedics in preoperative planning,...

  • Review
  • Open Access
141 Citations
16,428 Views
19 Pages

14 April 2010

Due to its excellent biocompatibility and mechanical properties, various different applications of polyvinyl alcohol-hydrogels (PVA-H) has been attempted in many fields. In the field of orthopedic surgery, we have been engaged for long time in resear...

  • Article
  • Open Access
15 Citations
3,757 Views
9 Pages

Effect of COVID-19 Pandemic on Orthopedic Surgery in Three Centers from Romania

  • Dinu Vermeşan,
  • Adrian Todor,
  • Diana Andrei,
  • Marius Niculescu,
  • Emanuela Tudorache and
  • Horia Haragus

The COVID-19 pandemic has put an enormous burden on healthcare systems. As a direct consequence, many elective procedures were cancelled and available resources were relocated to emergencies and COVID-19 patients. We aimed to analyze the impact on or...

  • Article
  • Open Access
9 Citations
3,436 Views
16 Pages

Microstructural Analysis of Fractured Orthopedic Implants

  • Mateusz Kopec,
  • Adam Brodecki,
  • Grzegorz Szczęsny and
  • Zbigniew L. Kowalewski

25 April 2021

In this paper, fracture behavior of four types of implants with different geometries (pure titanium locking plate, pure titanium femoral implant, Ti-6Al-4V titanium alloy pelvic implant, X2CrNiMo18 14-3 steel femoral implant) was studied in detail. E...

  • Article
  • Open Access
2,305 Views
12 Pages

The Benefit of an Umbrella Protocol: Reducing Challenges in Orthopedic Oncology Research

  • Samuel K. Simister,
  • Shannon Tse,
  • Aziz Saade,
  • Chancey A. Sweeney,
  • Barton L. Wise,
  • Steven W. Thorpe and
  • R. Lor Randall

8 March 2024

Background: Orthopedic oncology research is hindered by the scarcity of musculoskeletal tumors and research administrative inefficiencies. This paper introduces observational research through an innovative institution-specific methodology—terme...

  • Review
  • Open Access
5 Citations
4,431 Views
25 Pages

Vitamin D Metabolic Pathway Components in Orthopedic Patientes—Systematic Review

  • Janusz Płomiński,
  • Roman Grzybowski,
  • Ewa Fiedorowicz,
  • Edyta Sienkiewicz-Szłapka,
  • Dominika Rozmus,
  • Angelika Król-Grzymała,
  • Beata Jarmołowska,
  • Natalia Kordulewska and
  • Anna Cieślińska

8 December 2022

Vitamin D takes part in the functioning of many processes that ensure the homeostasis of the body. In orthopedics, it is indicated as an inseparable element ensuring proper bone growth and functioning, and its deficiencies are indicated in various di...

  • Feature Paper
  • Article
  • Open Access
1 Citations
1,605 Views
10 Pages

The Effects of the COVID-19 Pandemic on Pediatric Orthopedic Injuries: A Single-Center Retrospective Study

  • Betina Hinckel,
  • Sazid Hasan,
  • Clark Yin,
  • Jimmy Lau,
  • Saeed Saleh and
  • Ehab Saleh

19 October 2024

Objectives: The COVID-19 pandemic has had a profound effect on the pediatric population worldwide. The consequences of the lockdown and the reallocation of hospital resources have caused notable changes in the presentation of pediatric orthopedic inj...

  • Review
  • Open Access
27 Citations
8,802 Views
23 Pages

11 August 2023

Venous thromboembolism (VTE), comprising pulmonary embolism (PE) and deep vein thrombosis (DVT), poses a significant risk during and after hospitalization, particularly for surgical patients. Among various patient groups, those undergoing major ortho...

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