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  • Article
  • Open Access
5 Citations
3,308 Views
21 Pages

Implementation of Biocontrol Macro-Organisms in France

  • Marion Baratange,
  • Johana Cardoso,
  • Diane C. Robin and
  • Patrice A. Marchand

12 July 2023

The use of macro-organisms for crop protection is one of the four pillars of biocontrol. These predators or parasitoids of crop pests are used, by introduction or conservation, in fields, greenhouses and orchards in order to reduce the impact of suck...

  • Article
  • Open Access
28 Citations
7,324 Views
11 Pages

Traces of Locomotion of Ediacaran Macroorganisms

  • Andrey Ivantsov,
  • Aleksey Nagovitsyn and
  • Maria Zakrevskaya

11 September 2019

We describe traces of macroorganisms in association with the body imprints of trace-producers from Ediacaran (Vendian) deposits of the southeastern White Sea region. They are interpreted as traces of locomotion and are not directly related to a food...

  • Article
  • Open Access
12 Citations
3,144 Views
16 Pages

The ecosystem of the abyss is one of the fields that humans hardly know. The ultra-high hydrostatic pressure makes it very difficult to obtain abyssal organisms. Samples are often severely broken during recovery due to changes in environmental pressu...

  • Article
  • Open Access
3 Citations
1,740 Views
15 Pages

Metabolites from Marine Macroorganisms of the Red Sea Acting as Promoters or Inhibitors of Amylin Aggregation

  • Mawadda Alghrably,
  • Mohamed A. Tammam,
  • Aikaterini Koutsaviti,
  • Vassilios Roussis,
  • Xabier Lopez,
  • Giulia Bennici,
  • Abeer Sharfalddin,
  • Hanan Almahasheer,
  • Carlos M. Duarte and
  • Mariusz Jaremko
  • + 2 authors

6 August 2024

Amylin is part of the endocrine pancreatic system that contributes to glycemic control, regulating blood glucose levels. However, human amylin has a high tendency to aggregate, forming isolated amylin deposits that are observed in patients with type...

  • Article
  • Open Access
5 Citations
2,608 Views
25 Pages

Long-Term Integrated Systems of Green Manure and Pasture Significantly Recover the Macrofauna of Degraded Soil in the Brazilian Savannah

  • Carolina dos Santos Batista Bonini,
  • Thais Monique de Souza Maciel,
  • Bruno Rafael de Almeida Moreira,
  • José Guilherme Marques Chitero,
  • Rodney Lúcio Pinheiro Henrique and
  • Marlene Cristina Alves

Healthy soil biota is the key to meeting the world population’s growing demand for food, energy, fiber and raw materials. Our aim is to investigate the effect of green manure as a strategy to recover the macrofauna and the chemical properties o...

  • Article
  • Open Access
2 Citations
2,716 Views
16 Pages

15 December 2022

Hadal seafloor organisms live under ultra-high pressure, in low temperatures, and other environments for a long time, which puts higher requirements on the structural design of deep-sea biological samplers. In this paper, we present a full-ocean-dept...

  • Article
  • Open Access
58 Citations
13,354 Views
13 Pages

Evaluation of the Activity of the Sponge Metabolites Avarol and Avarone and their Synthetic Derivatives Against Fouling Micro- and Macroorganisms

  • Maria Tsoukatou,
  • Jean Philippe Maréchal,
  • Claire Hellio,
  • Irena Novaković,
  • Srdan Tufegdzic,
  • Dusan Sladić,
  • Miroslav J Gašić,
  • Anthony S Clare,
  • Constantinos Vagias and
  • Vassilios Roussis

15 May 2007

The sesquiterpene hydroquinone avarol (1) was isolated from the marine sponge Dysidea avara, whereas the corresponding quinone, avarone (2), was obtained by oxidation of avarol, and the significantly more lipophilic compounds [3’-(p-chloro-phenyl)ava...

  • Review
  • Open Access
7 Citations
2,965 Views
19 Pages

3 October 2022

A number of bacteria that colonize the human body produce toxins and effectors that cause changes in the eukaryotic cell cycle—cyclomodulins and low-molecular-weight compounds such as butyrate, lactic acid, and secondary bile acids. Cyclomoduli...

  • Opinion
  • Open Access
2 Citations
1,810 Views
9 Pages

28 September 2025

More than five decades before the introduction of “environmental filtering” in plant and vegetation sciences, Baas Becking proposed that the “environment selects” for studies in microbial ecology. He coupled this with the ubiq...

  • Review
  • Open Access
38 Citations
11,548 Views
14 Pages

Flower Strips and Their Ecological Multifunctionality in Agricultural Fields

  • Jolanta Kowalska,
  • Małgorzata Antkowiak and
  • Paweł Sienkiewicz

14 September 2022

Flower strips can be an important component of integrated pest management and contribute to reducing pressure on agroecosystems, which is why they are increasingly implemented as part of agri-environmental programs. They can be used as a multifunctio...

  • Article
  • Open Access
1 Citations
1,519 Views
12 Pages

Assessing the Modulatory Effects of Biochar on Soil Health Status in Response to Pesticide Application

  • Giovanna B. Melas,
  • Oriol Ortiz,
  • Amira M. Roshdy,
  • Mohamed Y. Hendawi,
  • Dimitrios Triantakonstantis and
  • Sameh Shaddad

11 April 2025

Considering the global competition to increase food productivity due to the increasing population growth, the use of chemical pesticides has become the quick solution, but by increasing awareness about the serious dangers of wasteful chemicals in var...

  • Perspective
  • Open Access
18 Citations
6,231 Views
20 Pages

26 April 2022

As the quest for marine-derived compounds with pharmacological and biotechnological potential upsurges, the importance of following regulations and applying Responsible Research and Innovation (RRI) also increases. This article aims at: (1) presentin...

  • Review
  • Open Access
36 Citations
10,040 Views
28 Pages

Natural Products Repertoire of the Red Sea

  • Ebaa M. El-Hossary,
  • Mohammad Abdel-Halim,
  • Eslam S. Ibrahim,
  • Sheila Marie Pimentel-Elardo,
  • Justin R. Nodwell,
  • Heba Handoussa,
  • Miada F. Abdelwahab,
  • Ulrike Holzgrabe and
  • Usama Ramadan Abdelmohsen

4 September 2020

Marine natural products have achieved great success as an important source of new lead compounds for drug discovery. The Red Sea provides enormous diversity on the biological scale in all domains of life including micro- and macro-organisms. In this...

  • Review
  • Open Access
166 Citations
14,651 Views
26 Pages

Spotlight on Antimicrobial Metabolites from the Marine Bacteria Pseudoalteromonas: Chemodiversity and Ecological Significance

  • Clément Offret,
  • Florie Desriac,
  • Patrick Le Chevalier,
  • Jérôme Mounier,
  • Camille Jégou and
  • Yannick Fleury

8 July 2016

This review is dedicated to the antimicrobial metabolite-producing Pseudoalteromonas strains. The genus Pseudoalteromonas hosts 41 species, among which 16 are antimicrobial metabolite producers. To date, a total of 69 antimicrobial compounds belongin...

  • Article
  • Open Access
13 Citations
3,294 Views
18 Pages

The Interaction of Biofoulants and Calcareous Deposits on Corrosion Performance of Q235 in Seawater

  • Jie Zhang,
  • Zhenhua Yu,
  • Xia Zhao,
  • Xiao Lan,
  • Jiangwei Wang,
  • Xianzi Lv,
  • Chao Zhang,
  • Jizhou Duan and
  • Baorong Hou

13 February 2020

An understanding of the interaction of calcareous deposits and biofoulants on the corrosion performance of steel during the fouling stage is both interesting and necessary. So, the effects of these factors on Q235 carbon steel were investigated and d...

  • Article
  • Open Access
38 Citations
5,801 Views
23 Pages

Influence of the Intrinsic Characteristics of Cementitious Materials on Biofouling in the Marine Environment

  • Mahmoud Hayek,
  • Marie Salgues,
  • Jean-Claude Souche,
  • Etienne Cunge,
  • Cyril Giraudel and
  • Osanne Paireau

1 March 2021

Coastal marine ecosystems provide essential benefits and services to humanity, but many are rapidly degrading. Human activities are leading to significant land take along coastlines and to major changes in ecosystems. Ecological engineering tools cap...

  • Editorial
  • Open Access
4 Citations
7,983 Views
4 Pages

Recent Advances in Applied Microbiology: Editorial

  • Letícia M. Estevinho,
  • Patrícia Combarros-Fuertes and
  • Vanessa Branco Paula

The importance of microbiology has grown exponentially since the development of genomics, transcriptomics, and proteomics, making it possible to clarify microbial biogeochemical processes and their interactions with macroorganisms in both health and...

  • Review
  • Open Access
58 Citations
15,023 Views
21 Pages

Tetranychus urticae is one of the most important pests of many species of economically important crops, cultivated both under cover and in open ground. Feeding T. urticae reduces the size and quality of the yield. Nowadays, in connection with the pop...

  • Review
  • Open Access
15 Citations
3,968 Views
25 Pages

Proof of Concept of Natural and Synthetic Antifouling Agents in Coatings

  • Daniela Pereira,
  • Joana R. Almeida,
  • Honorina Cidade and
  • Marta Correia-da-Silva

24 June 2024

Marine biofouling, caused by the deposition and accumulation of marine organisms on submerged surfaces, represents a huge concern for the maritime industries and also contributes to environmental pollution and health concerns. The most effective way...

  • Review
  • Open Access
35 Citations
18,290 Views
60 Pages

Marine Natural Products from New Caledonia—A Review

  • Sofia-Eléna Motuhi,
  • Mohamed Mehiri,
  • Claude Elisabeth Payri,
  • Stéphane La Barre and
  • Stéphane Bach

16 March 2016

Marine micro- and macroorganisms are well known to produce metabolites with high biotechnological potential. Nearly 40 years of systematic prospecting all around the New Caledonia archipelago and several successive research programs have uncovered ne...

  • Review
  • Open Access
99 Citations
17,473 Views
31 Pages

21 September 2017

Microbial symbiotic communities of marine macro-organisms carry functional metabolic profiles different to the ones found terrestrially and within surrounding marine environments. These symbiotic bacteria have increasingly been a focus of microbiolog...

  • Review
  • Open Access
5 Citations
6,828 Views
22 Pages

Anti-Biofilm Extracts and Molecules from the Marine Environment

  • Flore Caudal,
  • Catherine Roullier,
  • Sophie Rodrigues,
  • Alain Dufour,
  • Sébastien Artigaud,
  • Gwenaelle Le Blay,
  • Alexis Bazire and
  • Sylvain Petek

10 July 2024

Pathogenic bacteria and their biofilms are involved in many diseases and represent a major public health problem, including the development of antibiotic resistance. These biofilms are known to cause chronic infections for which conventional antibiot...

  • Article
  • Open Access
3 Citations
4,051 Views
14 Pages

7 April 2023

The symbiotic relationship between macroorganisms, such as plants and animals, and the microorganisms in their environment plays a crucial role in shaping their physiology and ecology. Thus, many studies have examined microbial symbiosis in relation...

  • Review
  • Open Access
12 Citations
4,105 Views
23 Pages

Marine Compounds for Melanoma Treatment and Prevention

  • Eleonora Montuori,
  • Anita Capalbo and
  • Chiara Lauritano

7 September 2022

Melanoma is considered a multifactorial disease etiologically divided into melanomas related to sun exposure and those that are not, but also based on their mutational signatures, anatomic site, and epidemiology. The incidence of melanoma skin cancer...

  • Article
  • Open Access
6 Citations
4,226 Views
14 Pages

Effects of Dysbiosis and Dietary Manipulation on the Digestive Microbiota of a Detritivorous Arthropod

  • Marius Bredon,
  • Elisabeth Depuydt,
  • Lucas Brisson,
  • Laurent Moulin,
  • Ciriac Charles,
  • Sophie Haenn,
  • Bouziane Moumen and
  • Didier Bouchon

The crucial role of microbes in the evolution, development, health, and ecological interactions of multicellular organisms is now widely recognized in the holobiont concept. However, the structure and stability of microbiota are highly dependent on a...

  • Article
  • Open Access
56 Citations
7,399 Views
19 Pages

Antifouling Napyradiomycins from Marine-Derived Actinomycetes Streptomyces aculeolatus

  • Florbela Pereira,
  • Joana R. Almeida,
  • Marisa Paulino,
  • Inês R. Grilo,
  • Helena Macedo,
  • Isabel Cunha,
  • Rita G. Sobral,
  • Vitor Vasconcelos and
  • Susana P. Gaudêncio

18 January 2020

The undesired attachment of micro and macroorganisms on water-immersed surfaces, known as marine biofouling, results in severe prevention and maintenance costs (billions €/year) for aquaculture, shipping and other industries that rely on coastal and...

  • Review
  • Open Access
46 Citations
11,525 Views
11 Pages

13 November 2007

Polymeric 3-alkylpyridinium salts (poly-APS) present in the marine spongeReniera sarai show a broad spectrum of biological activities. They are lytic to erythrocytesand various other mammalian cells, enabling the transfection of the latter with alien...

  • Review
  • Open Access
81 Citations
17,203 Views
26 Pages

Microbial pigments play multiple roles in the ecosystem construction, survival, and fitness of all kinds of organisms. Considerably, microbial (bacteria, fungi, yeast, and microalgae) pigments offer a wide array of food, drug, colorants, dyes, and im...

  • Review
  • Open Access
23 Citations
5,463 Views
19 Pages

Gut Microbiome Composition and Its Metabolites Are a Key Regulating Factor for Malignant Transformation, Metastasis and Antitumor Immunity

  • Stefan Lozenov,
  • Boris Krastev,
  • Georgi Nikolaev,
  • Monika Peshevska-Sekulovska,
  • Milena Peruhova and
  • Tsvetelina Velikova

The genetic and metabolomic abundance of the microbiome exemplifies that the microbiome comprises a more extensive set of genes than the entire human genome, which justifies the numerous metabolic and immunological interactions between the gut microb...

  • Article
  • Open Access
6 Citations
3,675 Views
14 Pages

31 March 2022

Mycosporine-like amino acids are a prevalent form of photoprotection in micro- and macro-organisms. Using a combination of natural product extraction/purification and femtosecond transient absorption spectroscopy, we studied the relaxation pathway fo...

  • Review
  • Open Access
21 Citations
6,138 Views
30 Pages

12 January 2022

In humid environments, the formation of biofilms and microfouling are known to be the detrimental processes that first occur on stainless steel surfaces. This is known as biofouling. Subsequently, the conditions created by metabolites and the activit...

  • Review
  • Open Access
59 Citations
9,025 Views
39 Pages

Marine-Derived Indole Alkaloids and Their Biological and Pharmacological Activities

  • Joko Tri Wibowo,
  • Peni Ahmadi,
  • Siti Irma Rahmawati,
  • Asep Bayu,
  • Masteria Yunovilsa Putra and
  • Anake Kijjoa

21 December 2021

Novel secondary metabolites from marine macroorganisms and marine-derived microorganisms have been intensively investigated in the last few decades. Several classes of compounds, especially indole alkaloids, have been a target for evaluating biologic...

  • Review
  • Open Access
65 Citations
21,329 Views
18 Pages

17 January 2022

This article describes the importance of rearing insects, whether on a small scale for research or a large scale for mass rearing, for use in biological control (BC) programs with macro-organisms. These inter- or multidisciplinary research programs a...

  • Review
  • Open Access
61 Citations
9,900 Views
20 Pages

Phylogeny and Biogeography of Cyanobacteria and Their Produced Toxins

  • Cristiana Moreira,
  • Vitor Vasconcelos and
  • Agostinho Antunes

1 November 2013

Phylogeny is an evolutionary reconstruction of the past relationships of DNA or protein sequences and it can further be used as a tool to assess population structuring, genetic diversity and biogeographic patterns. In the microbial world, the concept...

  • Review
  • Open Access
12 Citations
4,312 Views
44 Pages

Marine Natural Products from the Beibu Gulf: Sources, Chemistry, and Bioactivities

  • Jiamin Wang,
  • Yuning Qin,
  • Miaoping Lin,
  • Yingying Song,
  • Humu Lu,
  • Xinya Xu,
  • Yonghong Liu,
  • Xuefeng Zhou,
  • Chenghai Gao and
  • Xiaowei Luo

19 January 2023

Marine natural products (MNPs) play an important role in the discovery and development of new drugs. The Beibu Gulf of South China Sea harbors four representative marine ecosystems, including coral reefs, mangroves, seaweed beds, and coastal wetlands...

  • Review
  • Open Access
135 Citations
18,063 Views
28 Pages

Marine Anticancer Agents: An Overview with a Particular Focus on Their Chemical Classes

  • Marilia Barreca,
  • Virginia Spanò,
  • Alessandra Montalbano,
  • Mercedes Cueto,
  • Ana R. Díaz Marrero,
  • Irem Deniz,
  • Ayşegül Erdoğan,
  • Lada Lukić Bilela,
  • Corentin Moulin and
  • Francesco Bertoni
  • + 8 authors

4 December 2020

The marine environment is a rich source of biologically active molecules for the treatment of human diseases, especially cancer. The adaptation to unique environmental conditions led marine organisms to evolve different pathways than their terrestria...

  • Article
  • Open Access
15 Citations
4,721 Views
15 Pages

Profiling of Heterobranchia Sea Slugs from Portuguese Coastal Waters as Producers of Anti-Cancer and Anti-Inflammatory Agents

  • Nelson G. M. Gomes,
  • Fátima Fernandes,
  • Áurea Madureira-Carvalho,
  • Patrícia Valentão,
  • Alexandre Lobo-da-Cunha,
  • Gonçalo Calado and
  • Paula B. Andrade

27 April 2018

Bioprospection of marine invertebrates has been predominantly biased by the biological richness of tropical regions, thus neglecting macro-organisms from temperate ecosystems. Species that were not the object of studies on their biochemical compositi...

  • Article
  • Open Access
9 Citations
2,916 Views
14 Pages

Spatial Succession for Degradation of Solid Multicomponent Food Waste and Purification of Toxic Leachate with the Obtaining of Biohydrogen and Biomethane

  • Oleksandr Tashyrev,
  • Vira Hovorukha,
  • Olesia Havryliuk,
  • Iryna Sioma,
  • Galina Gladka,
  • Olga Kalinichenko,
  • Paweł Włodarczyk,
  • Dariusz Suszanowicz,
  • Hennadiy Zhuk and
  • Yuri Ivanov

27 January 2022

A huge amount of organic waste is generated annually around the globe. The main sources of solid and liquid organic waste are municipalities and canning and food industries. Most of it is disposed of in an environmentally unfriendly way since none of...

  • Feature Paper
  • Review
  • Open Access
89 Citations
14,804 Views
45 Pages

Biomaterials and Bioactive Natural Products from Marine Invertebrates: From Basic Research to Innovative Applications

  • Giovanna Romano,
  • Mariana Almeida,
  • Ana Varela Coelho,
  • Adele Cutignano,
  • Luis G Gonçalves,
  • Espen Hansen,
  • Denis Khnykin,
  • Tali Mass,
  • Andreja Ramšak and
  • Anne-Marie Genevière
  • + 4 authors

22 March 2022

Aquatic invertebrates are a major source of biomaterials and bioactive natural products that can find applications as pharmaceutics, nutraceutics, cosmetics, antibiotics, antifouling products and biomaterials. Symbiotic microorganisms are often the r...

  • Article
  • Open Access
13 Citations
9,617 Views
16 Pages

10 January 2011

In the search for bioactive natural products, our lab screens hydrophobic extracts from marine fungal strains. While hydrophilic active substances were recently identified from marine macro-organisms, there was a lack of reported metabolites in the m...

  • Article
  • Open Access
2 Citations
3,842 Views
13 Pages

Butanolides and Butenolides from a Marine-Derived Streptomyces sp. Exert Neuroprotective Activity through Activation of the TrkB Neurotrophin Receptor

  • Paolo Giaccio,
  • Despoina Charou,
  • Dafni-Ioanna Diakaki,
  • Anna Chita,
  • Achille Gravanis,
  • Ioannis Charalampopoulos,
  • Vassilios Roussis and
  • Efstathia Ioannou

25 August 2023

Neurodegenerative diseases are incurable and debilitating conditions, characterized by progressive loss and degeneration of vulnerable neuronal populations. Currently, there are no effective therapies available for the treatment of most neurodegenera...

  • Article
  • Open Access
8 Citations
3,268 Views
23 Pages

Appendage-Bearing Sordariomycetes from Dipterocarpus alatus Leaf Litter in Thailand

  • Nethmini P. Samaradiwakara,
  • Antonio Roberto Gomes de Farias,
  • Danushka S. Tennakoon,
  • Janith V. S. Aluthmuhandiram,
  • Chitrabhanu S. Bhunjun,
  • K. W. Thilini Chethana,
  • Jaturong Kumla and
  • Saisamorn Lumyong

29 May 2023

Leaf litter is an essential functional aspect of forest ecosystems, acting as a source of organic matter, a protective layer in forest soils, and a nurturing habitat for micro- and macro-organisms. Through their successional occurrence, litter-inhabi...

  • Review
  • Open Access
15 Citations
6,973 Views
65 Pages

Advanced Technologies for Large Scale Supply of Marine Drugs

  • Henar Martínez,
  • Mercedes Santos,
  • Lucía Pedraza and
  • Ana M. Testera

7 February 2025

Marine organisms represent a source of unique chemical entities with valuable biomedical potentialities, broad diversity, and complexity. It is essential to ensure a reliable and sustainable supply of marine natural products (MNPs) for their translat...

  • Article
  • Open Access
10 Citations
8,646 Views
24 Pages

Assessing the Antimicrobial Activity of Polyisoprene Based Surfaces

  • Hope Badawy,
  • Jérôme Brunellière,
  • Marina Veryaskina,
  • Guillaume Brotons,
  • Sophie Sablé,
  • Isabelle Lanneluc,
  • Kelly Lambert,
  • Pascal Marmey,
  • Amy Milsted and
  • Pamela Pasetto
  • + 3 authors

19 February 2015

There has been an intense research effort in the last decades in the field of biofouling prevention as it concerns many aspects of everyday life and causes problems to devices, the environment, and human health. Many different antifouling and antimic...

  • Review
  • Open Access
10 Citations
4,431 Views
25 Pages

Promising Activities of Marine Natural Products against Hematopoietic Malignancies

  • Assunta Saide,
  • Sara Damiano,
  • Roberto Ciarcia and
  • Chiara Lauritano

According to the WHO classification of tumors, more than 150 typologies of hematopoietic and lymphoid tumors exist, and most of them remain incurable diseases that require innovative approaches to improve therapeutic outcome and avoid side effects. M...

  • Review
  • Open Access
32 Citations
5,397 Views
23 Pages

Both latent and active TB infections are caused by a heterogeneous population of mycobacteria, which includes actively replicating and dormant bacilli in different proportions. Dormancy substantially affects M. tuberculosis drug tolerance and TB clin...

  • Review
  • Open Access
43 Citations
7,326 Views
30 Pages

Flavonoids Are Intra- and Inter-Kingdom Modulator Signals

  • Elisa Ghitti,
  • Eleonora Rolli,
  • Elena Crotti and
  • Sara Borin

Flavonoids are a broad class of secondary metabolites with multifaceted functionalities for plant homeostasis and are involved in facing both biotic and abiotic stresses to sustain plant growth and health. Furthermore, they were discovered as mediato...

  • Feature Paper
  • Article
  • Open Access
5 Citations
4,252 Views
19 Pages

Evaluating Multiple Stressor Effects on Benthic–Pelagic Freshwater Communities in Systems of Different Complexities: Challenges in Upscaling

  • Vinita Vijayaraj,
  • Nora Kipferler,
  • Herwig Stibor,
  • Joey Allen,
  • Franz Hölker,
  • Martin Laviale,
  • Joséphine Leflaive,
  • Gregorio Alejandro López Moreira Mazacotte,
  • Bastian Herbert Polst and
  • Elisabeth Maria Gross
  • + 2 authors

14 February 2022

Upscaling of ecological effects from indoor microcosms to outdoor mesocosms bridging the gap between controlled laboratory conditions and highly complex natural environments poses several challenges: typical standard water types used in laboratory ex...

  • Article
  • Open Access
8 Citations
6,766 Views
17 Pages

Simple Soil Tests for On-Site Evaluation of Soil Health in Orchards

  • Esther O. Thomsen,
  • Jennifer R. Reeve,
  • Catherine M. Culumber,
  • Diane G. Alston,
  • Robert Newhall and
  • Grant Cardon

29 October 2019

Standard commercial soil tests typically quantify nitrogen, phosphorus, potassium, pH, and salinity. These factors alone are not sufficient to predict the long-term effects of management on soil health. The goal of this study was to assess the effect...

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