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  • Review
  • Open Access
40 Citations
13,348 Views
19 Pages

The Burden of Sepsis and Septic Shock in the Intensive Care Unit

  • Luigi La Via,
  • Antonino Maniaci,
  • Mario Lentini,
  • Giuseppe Cuttone and ,
  • Salvatore Ronsivalle,
  • Simona Tutino,
  • Francesca Maria Rubulotta,
  • Giuseppe Nunnari and
  • Andrea Marino
  • + 4 authors+ 0 author

23 September 2025

This narrative review synthesizes our current understanding of sepsis and septic shock burden in intensive care units (ICUs) worldwide. Based on a comprehensive but non-systematic literature search from 2000 to 2025, this review synthesizes our curre...

(This article belongs to the Section Emergency Medicine)
  • Article
  • Open Access
1,849 Views
14 Pages

Evaluation of Respiratory Intensive Care Experiences and Relationships with Nutritional Status Among Patients Admitted to the Intensive Care Unit

  • Murat Yildiz,
  • Deniz Celik,
  • Tarkan Ozdemir,
  • Kerem Ensarioglu and ,
  • Melek Cakir,
  • Tugce Dondu Savur,
  • Oral Mentes and
  • Mustafa Ozgur Cirik
  • + 3 authors+ 0 author

19 February 2025

Background and Objectives: This study aimed to evaluate patients’ experiences in the intensive care unit (ICU) setting and investigate whether there was a correlation between these experiences and their nutritional status. Materials and Methods...

(This article belongs to the Section Intensive Care/ Anesthesiology)
  • Article
  • Open Access
6 Citations
2,945 Views
17 Pages

Challenges of the Implementation of a Delirium Rate Scale in a Pediatric Intensive Care Unit: A Qualitative Approach

  • Paula Balsalobre-Martínez,
  • Raquel Montosa-García,
  • Ana Marín-Yago,
  • Manuel Baeza-Mirete and ,
  • Gloria María Muñoz-Rubio and
  • Andrés Rojo-Rojo
  • + 1 author+ 0 author

26 December 2023

Introduction: Delirium in the pediatric population admitted to intensive care is a worrying reality due to its potential complications and the increase in associated costs. This study aims to explore the experiences of nursing staff of a Pediatric In...

  • Article
  • Open Access
8 Citations
4,687 Views
12 Pages

Parents’ Participation in Care during Neonatal Intensive Care Unit Stay in COVID-19 Era: An Observational Study

  • Emanuele Buccione,
  • Davide Scarponcini Fornaro,
  • Damiana Pieragostino,
  • Luca Natale and ,
  • Adelaide D’Errico,
  • Valentina Chiavaroli,
  • Laura Rasero,
  • Stefano Bambi,
  • Carlo Della Pelle and
  • Susanna Di Valerio
  • + 5 authors+ 0 author

13 May 2024

Background: Parents play a crucial role in the care of infants during their stay in the neonatal intensive care unit (NICU). Recent studies have reported a decrease in parental participation due to the coronavirus disease (COVID-19) pandemic, which h...

  • Review
  • Open Access
26 Citations
8,724 Views
17 Pages

19 February 2019

In the last few years, important changes have occurred in the clinical and epidemiological characteristics of patients that were admitted to cardiac intensive care units (CICU). Care has shifted from acute coronary syndrome patients towards elderly p...

(This article belongs to the Special Issue Recent Advances in Palliative Care)
  • Review
  • Open Access
6 Citations
6,863 Views
8 Pages

Sleeping Soundlessly in the Intensive Care Unit

  • Kendall J. Burdick and
  • Christine J. Callahan

An estimated 70% of patients who have been in the Intensive Care Unit (ICU) experience some form of Post-Intensive Care Syndrome (PICS). As a stressful environment, the ICU can be traumatic for any patient; however, the disruption of sleep experience...

  • Article
  • Open Access
12 Citations
6,081 Views
17 Pages

Impact of Wound Dressing Changes on Nursing Workload in an Intensive Care Unit

  • Juliana Dias dos Reis,
  • Pedro Sa-Couto,
  • José Mateus,
  • Carlos Jorge Simões and ,
  • Alexandre Rodrigues,
  • Pedro Sardo and
  • João Lindo Simões
  • + 2 authors+ 0 author

The objective of this study is to understand how the type of wound dressing changes (routine or frequent) in patients admitted to intensive care units influences nurses’ workload. This study used a database of retrospective and analytical obser...

  • Article
  • Open Access
8 Citations
2,239 Views
9 Pages

20 November 2024

Objectives: The aim of this study is to assess the oxidative stress status in patients requiring intensive care unit (ICU) admission before initiating ICU treatment, by measuring the total oxidant level (TOS) and total antioxidant level (TAS) and oxi...

(This article belongs to the Section Intensive Care)
  • Article
  • Open Access
32 Citations
6,307 Views
13 Pages

Using Explainable Machine Learning to Improve Intensive Care Unit Alarm Systems

  • José A. González-Nóvoa,
  • Laura Busto,
  • Juan J. Rodríguez-Andina,
  • José Fariña and ,
  • Marta Segura,
  • Vanesa Gómez,
  • Dolores Vila and
  • César Veiga
  • + 3 authors+ 0 author

27 October 2021

Due to the continuous monitoring process of critical patients, Intensive Care Units (ICU) generate large amounts of data, which are difficult for healthcare personnel to analyze manually, especially in overloaded situations such as those present duri...

(This article belongs to the Special Issue Explainable AI in Medical Sensors)
  • Article
  • Open Access
5 Citations
4,166 Views
8 Pages

Workforce and Task Sharing of Nurses in the Japanese Intensive Care Unit-Cross-Sectional Postal Survey

  • Takeshi Unoki,
  • Yusuke Kawai,
  • Miya Hamamoto,
  • Mitsuhiro Tamoto and ,
  • Takeharu Miyamoto,
  • Hideaki Sakuramoto,
  • Yumi Ito,
  • Etsuko Moro,
  • Junko Tatsuno and
  • Osamu Nishida
  • + 5 authors+ 0 author

This study aimed to estimate the number of nurses who independently care for patients with severe respiratory failure receiving mechanical ventilation (MV) or veno-venous extracorporeal membrane oxygenation (VV-ECMO). Additionally, the study analyzed...

  • Review
  • Open Access
29 Citations
11,350 Views
14 Pages

Acute Kidney Injury in Neonatal Intensive Care Unit: Epidemiology, Diagnosis and Risk Factors

  • Valeria Chirico,
  • Antonio Lacquaniti,
  • Filippo Tripodi,
  • Giovanni Conti and ,
  • Lucia Marseglia,
  • Paolo Monardo,
  • Eloisa Gitto and
  • Roberto Chimenz
  • + 3 authors+ 0 author

13 June 2024

Acute kidney injury (AKI) is associated with long-term consequences and poor outcomes in the neonatal intensive care unit. Its precocious diagnosis represents one of the hardest challenges in clinical practice due to the lack of sensitive and specifi...

(This article belongs to the Section Clinical Pediatrics)
  • Article
  • Open Access
5 Citations
7,778 Views
14 Pages

Arterial Blood Gas Analysis and Clinical Decision-Making in Emergency and Intensive Care Unit Nurses: A Performance Evaluation

  • Arian Zaboli,
  • Chiara Biasi,
  • Gabriele Magnarelli,
  • Barbara Miori and ,
  • Magdalena Massar,
  • Norbert Pfeifer,
  • Francesco Brigo and
  • Gianni Turcato
  • + 3 authors+ 0 author

28 January 2025

Background: This study aimed to evaluate Emergency Department and Intensive Care Unit nurses’ skills in interpreting blood gas analysis results and to use those interpretations in clinical decision-making. Methods: In this prospective, multicen...

(This article belongs to the Special Issue Healthcare Simulation, Artificial Intelligence and Interprofessional Collaboration)
  • Review
  • Open Access
1,144 Views
14 Pages

Flexible Bronchoscopy in the Intensive Care Unit: Controversies, Clinical Applications, and the Expanding Role of Intensivists

  • Thushira Weerawarna,
  • Rajesh Mishra,
  • Sumara Tantray,
  • Manish Bharti and ,
  • Atul Mehta,
  • Semra Bilaceroglu,
  • Gaurav Mishra,
  • Ahsina Jahan and
  • Antonio Esquinas
  • + 4 authors+ 0 author

12 June 2026

Background: Flexible bronchoscopy (FB) has long been integral to pulmonology, but its bedside role in the intensive care unit (ICU) is expanding. Despite a lack of high-level evidence, FB remains a pivotal tool for airway visualization, sampling, and...

(This article belongs to the Section Intensive Care)
  • Review
  • Open Access
7 Citations
10,578 Views
19 Pages

Stroke Management in the Intensive Care Unit: Ischemic and Hemorrhagic Stroke Care

  • Aleksandar Sič,
  • Vasilis-Spyridon Tseriotis,
  • Božidar Belanović,
  • Marko Nemet and
  • Marko Baralić

26 November 2025

Stroke is the second-largest cause of death and disability worldwide, and many patients require intensive care for airway compromise, hemodynamic instability, cerebral edema, or systemic complications. This review summarizes key aspects of ICU manage...

  • Article
  • Open Access
12 Citations
1,852 Views
8 Pages

Fibrinogen-to-Albumin Ratio Predicts Mortality in COVID-19 Patients Admitted to the Intensive Care Unit

  • Abdulmecit Afşin,
  • Hakan Tibilli,
  • Yusuf Hoşoğlu,
  • Ramazan Asoğlu and ,
  • Ahmet Süsenbük,
  • Sezer Markit and
  • Verda Dinar Tuna
  • + 2 authors+ 0 author

21 October 2021

Introduction: Coronavirus disease 2019 (COVID-19) is an inflammatory disease, and serum albumin and fibrinogen are two important factors in systemic inflammation. We aimed to investigate the relationship between the fibrinogen-to-albumin ratio (FAR)...

  • Article
  • Open Access
372 Views
11 Pages

Etiology and Outcomes of Hypernatremia in a Tertiary Pediatric Intensive Care Unit: The Role of Disease Severity

  • Özlem Yüksel Aksoy,
  • Mustafa Orhan Duyar,
  • Serhat Kaya,
  • Binnaz Çelik and ,
  • Funda Baştuğ,
  • Murat Doğan,
  • Adem Dursun and
  • Serkan Özsoylu
  • + 3 authors+ 0 author

4 September 2026

Purpose: Hypernatremia is a common electrolyte disorder in pediatric intensive care units (PICU) and is associated with considerable morbidity and mortality. We aimed to evaluate underlying etiologies, clinical characteristics, and factors associated...

  • Systematic Review
  • Open Access
38 Citations
22,113 Views
21 Pages

Tissue Penetration of Antimicrobials in Intensive Care Unit Patients: A Systematic Review—Part II

  • Bruno Viaggi,
  • Alice Cangialosi,
  • Martin Langer,
  • Carlo Olivieri and ,
  • Andrea Gori,
  • Alberto Corona,
  • Stefano Finazzi and
  • Antonello Di Paolo
  • + 3 authors+ 0 author

3 September 2022

In patients that are admitted to intensive care units (ICUs), the clinical outcome of severe infections depends on several factors, as well as the early administration of chemotherapies and comorbidities. Antimicrobials may be used in off-label regim...

(This article belongs to the Special Issue Pharmacodinamic and Pharmacokinetics of Antibiotics in the Critically Ill)
  • Article
  • Open Access
3 Citations
2,407 Views
14 Pages

Psychometric Validation of the Parental Stressor Scale: Neonatal Intensive Care Unit (PSS:NICU) in a Greek Cohort of Parents of Hospitalized Neonates

  • Maria Tzeli,
  • Maria Alexiou,
  • Antigoni Sarantaki,
  • Giannoula Kyrkou and ,
  • Dimitrios Charalampopoulos,
  • Sofia Biti,
  • Marina Antoniadi,
  • Aikaterini Fotiou,
  • Anna Daskalaki and
  • Dimitra Metallinou
  • + 7 authors+ 2 authors

30 October 2025

Background/Objectives: The Parental Stressor Scale: Neonatal Intensive Care Unit (PSS:NICU) is one of the most widely used tools for assessing parental stress in neonatal intensive care settings. This study aimed to translate, culturally adapt and va...

  • Article
  • Open Access
1,190 Views
8 Pages

Impact of a Nutrition Protocol on Vitamin D Supplementation in a Pediatric Intensive Care Unit: A Retrospective Cohort Study

  • Maria Pérez Marin,
  • Vivianne Chanez,
  • Guillaume Maitre,
  • Laurence Boillat and ,
  • Frida Rizzati,
  • Pauline Lauwers and
  • Maria-Helena Perez
  • + 2 authors+ 0 author

13 October 2025

Background: Vitamin D deficiency (VDD) is highly prevalent in pediatric critically ill patients and is a potentially modifiable risk factor during critical illness. There are no established national or international recommendations for vitamin D supp...

  • Article
  • Open Access
907 Views
15 Pages

Outcomes of Burn Patients Admitted Initially to a Non-Burn Center Intensive Care Unit in Romania: A Retrospective Exploratory Study

  • Olga Grăjdieru,
  • Constantin Bodolea,
  • Vlad Moisoiu,
  • Cristina Petrișor and ,
  • Bogdan Tigu,
  • Andrea Szekely,
  • Rareș Streza and
  • Cătălin Constantinescu
  • + 3 authors+ 0 author

26 February 2026

Background and Objectives: Many burn patients are initially admitted to non-burn center intensive care units (ICUs) due to resource constraints, geographic barriers, or delayed transfer. Their management requires multidisciplinary, phase-specific cli...

(This article belongs to the Section Intensive Care/ Anesthesiology)
  • Feature Paper
  • Article
  • Open Access
30 Citations
11,649 Views
11 Pages

Spiritual Care: The Nurses’ Experiences in the Pediatric Intensive Care Unit

  • Lucila C. Nascimento,
  • Willyane A. Alvarenga,
  • Sílvia Caldeira,
  • Tâmisa M. Mica and ,
  • Fabiane C. S. Oliveira,
  • Raquel Pan,
  • Tabatha F. M. Santos,
  • Emília C. Carvalho and
  • Margarida Vieira
  • + 4 authors+ 0 author

9 March 2016

Physical aspects of disease management are often more evident than those related to spirituality or spiritual care. Spirituality may appear more crucial in pediatric intensive care units (PICUs) when patients are experiencing serious illness or end-o...

(This article belongs to the Special Issue Selected Papers from Spirituality in Healthcare Conference 2015 “Sowing the Seeds”)
  • Article
  • Open Access
72 Citations
6,055 Views
15 Pages

Rapid Whole-Exome Sequencing as a Diagnostic Tool in a Neonatal/Pediatric Intensive Care Unit

  • Robert Śmigiel,
  • Mateusz Biela,
  • Krzysztof Szmyd,
  • Michal Błoch and ,
  • Elżbieta Szmida,
  • Paweł Skiba,
  • Anna Walczak,
  • Piotr Gasperowicz,
  • Joanna Kosińska and
  • Rafał Płoski
  • + 18 authors+ 13 authors

13 July 2020

Genetic disorders are the leading cause of infant morbidity and mortality. Due to the large number of genetic diseases, molecular and phenotype heterogeneity and often severe course, these diseases remain undiagnosed. In infants with a suspected acut...

(This article belongs to the Special Issue Mitochondrial Disorders: Molecular, Clinical and Therapeutic Advances)
  • Review
  • Open Access
16 Citations
6,900 Views
14 Pages

Probiotics in the Intensive Care Unit

  • Alex R. Schuurman,
  • Robert F. J. Kullberg and
  • Willem Joost Wiersinga

The understanding of the gut microbiome in health and disease has shown tremendous progress in the last decade. Shaped and balanced throughout life, the gut microbiome is intricately related to the local and systemic immune system and a multitude of...

(This article belongs to the Special Issue Antimicrobial Therapy in Intensive Care Unit)
  • Article
  • Open Access
12 Citations
4,066 Views
9 Pages

Intensive-care unit nurses may experience difficulties in end-of-life care because of frustration or lethargy. The purpose of this study was to develop a mobile end-of-life care program for intensive-care unit nurses and evaluate the effects on compe...

  • Article
  • Open Access
11 Citations
4,875 Views
11 Pages

Diagnostic Value of Neutrophil CD64 in Sepsis Patients in the Intensive Care Unit: A Cross-Sectional Study

  • Huy Minh Pham,
  • Duy Ly Minh Nguyen,
  • Minh Cuong Duong,
  • Linh Thanh Tran and
  • Thao Thi Ngoc Pham

Little is known about the role of neutrophil CD64 (nCD64) in detecting sepsis early in Asian populations. We examined the cut-off and predictive values of nCD64 for diagnosing sepsis in Vietnamese intensive care units (ICU) patients. A cross-sectiona...

(This article belongs to the Section Diagnostic Microbiology and Infectious Disease)
  • Article
  • Open Access
6 Citations
2,492 Views
13 Pages

Candida albicans Horizontal Transmission in COVID-19 Patients Hospitalized in Intensive Care Unit

  • Magdalena Skóra,
  • Katharina Rosam,
  • Magdalena Namysł,
  • Anna Sepioło and ,
  • Mateusz Gajda,
  • Justyna Jędras,
  • Paweł Krzyściak,
  • Joanna Zorska,
  • Jerzy Wordliczek and
  • Jadwiga Wójkowska-Mach
  • + 8 authors+ 3 authors

13 December 2024

Background: Invasive candidiasis is a predominant mycosis in hospitalized patients, and Candida albicans is the species most often responsible for this infection. Most candidiasis cases originate from endogenous mycobiota; therefore, Candida strains...

(This article belongs to the Special Issue Fungal Infections in Intensive Care Medicine)
  • Review
  • Open Access
27 Citations
9,411 Views
13 Pages

Hospital Dentistry for Intensive Care Unit Patients: A Comprehensive Review

  • Mi-Kyoung Jun,
  • Jeong-Kui Ku,
  • Il-hyung Kim,
  • Sang-Yoon Park and ,
  • Jinson Hong,
  • Jae-Young Kim and
  • Jeong-Keun Lee
  • + 2 authors+ 0 author

19 August 2021

This study aimed to review the oral hygiene status, oral care guidelines, and outcomes of oral care in intensive care unit (ICU) patients from a dental perspective for effective oral care. A literature search using the keywords “Hospital dentistry” O...

(This article belongs to the Section Emergency Medicine)
  • Article
  • Open Access
36 Citations
6,216 Views
17 Pages

Stressful Experiences of Parents in the Paediatric Intensive Care Unit: Searching for the Most Intensive PICU Stressors

  • Ivana Debelić,
  • Anamaria Mikolčić,
  • Jovana Tihomirović,
  • Iva Barić and ,
  • Đurđica Lendić,
  • Željka Nikšić,
  • Barbara Šencaj and
  • Robert Lovrić
  • + 3 authors+ 0 author

Hospitalization of a child in the paediatric intensive care unit (PICU) is extremely stressful, both for the child and for his or her family. The purpose of this study was to gain deeper insight into the stressful experiences of parents of children h...

(This article belongs to the Special Issue Intensive and Critical Care Nursing Research)
  • Article
  • Open Access
2,200 Views
22 Pages

DataToCare: Predicting Treatments for Intensive Care Unit Patients Based on Similarity of Abnormalities

  • Shan Randhawa,
  • Abbas Shojaee,
  • Elisa Sorrentino,
  • Yifan Li and ,
  • Azza Abouzied and
  • Dennis Shasha
  • + 1 author+ 0 author

26 May 2025

Clinical decision-making lies at the heart of health care. Medical data collection has made it possible for clinical decision-making to be data-driven. However, data-driven systems for decision-making have so far worked only for a limited set of clin...

(This article belongs to the Collection Feature Papers in Algorithms and Mathematical Models for Computer-Assisted Diagnostic Systems)
  • Article
  • Open Access
6 Citations
3,067 Views
10 Pages

Supporting Clinical Decisions with Rapid Molecular Diagnostic Pneumonia Panel in Pediatric Intensive Care Unit: Single Center Experience in Turkiye

  • Gurkan Bozan,
  • Yalcin Kara,
  • Eylem Kiral,
  • Mahmut Can Kizil and ,
  • Ebru Kacmaz,
  • Tercan Us,
  • Gul Durmaz,
  • Omer Kilic and
  • Ener Cagri Dinleyici
  • + 4 authors+ 0 author

Introduction: Lower respiratory tract infections are the leading cause of morbidity and mortality in children worldwide. It is crucial to promptly conduct diagnostic investigations in order to determine the microbiological cause of pneumonia, since t...

(This article belongs to the Special Issue Antibiotic Resistance: Present Knowledge and Future Challenges)
  • Article
  • Open Access
9 Citations
5,124 Views
10 Pages

Use of Musical Intervention in the Pediatric Intensive Care Unit of a Developing Country: A Pilot Pre–Post Study

  • Federica Buzzi,
  • Nizar Bakir Yahya,
  • Simone Gambazza,
  • Filippo Binda and ,
  • Alessandro Galazzi,
  • Antonella Ferrari,
  • Stefano Crespan,
  • Hevan Adel Al-Atroushy,
  • Barbara Maria Cantoni and
  • Collaborative Group
  • + 6 authors+ 1 author

24 March 2022

Music is frequently used in different clinical settings, and it is implemented as a complementary, low-cost and useful intervention to reduce pain, anxiety and to improve relaxation. This pilot pre–post study aimed to examine the feasibility an...

(This article belongs to the Section Pediatric Nursing)
  • Article
  • Open Access
1 Citations
1,384 Views
17 Pages

Development of the Spanish Version of “Nurses’ Perceptions of Responsibility, Knowledge and Documentation Focusing on Enteral Nutrition and Nursing Practice Regarding Enteral Feeding in the Intensive Care Unit”

  • Vicente Doménech-Briz,
  • Vicente Gea-Caballero,
  • Elena Chover-Sierra,
  • Raúl Juárez-Vela and ,
  • Noelia Navas-Echazarreta,
  • Pablo del Pozo-Herce,
  • Marta Pardo-Bosch,
  • Aurora García-Tejedor,
  • Beatriz Sánchez-Hernando and
  • Antonio Martínez-Sabater
  • + 6 authors+ 1 author

Background: Adequate nutritional knowledge among intensive care nurses is essential for early identification of nutritional risk and prevention of complications in critically ill patients. The questionnaire “Nurses’ perceptions of respons...

  • Article
  • Open Access
1 Citations
3,257 Views
12 Pages

Effectiveness of Additional Preventive Measures for Pressure Injury Prevention in an Intensive Care Unit: A Retrospective Cohort Study

  • Carolina Martín-Meana,
  • José Manuel González-Darias,
  • Carmen D. Chinea-Rodríguez,
  • María del Cristo Robayna-Delgado and ,
  • María del Carmen Arroyo-López,
  • Ángeles Arias-Rodríguez,
  • Alejandro Jiménez-Sosa and
  • Patricia Fariña-Martín
  • + 3 authors+ 0 author

Background/Objectives: Pressure injuries (PIs), a recognized indicator of care quality, have a higher incidence in intensive care units (ICUs). Our objective was to assess whether critically ill patients identified as “unprotected” (COMHO...

  • Article
  • Open Access
22 Citations
8,955 Views
8 Pages

Outbreak of Ampicillin/Piperacillin-Resistant Klebsiella Pneumoniae in a Neonatal Intensive Care Unit (NICU): Investigation and Control Measures

  • Giuliana Fabbri,
  • Manuela Panico,
  • Laura Dallolio,
  • Roberta Suzzi and ,
  • Matilde Ciccia,
  • Fabrizio Sandri and
  • Patrizia Farruggia
  • + 2 authors+ 0 author

Klebsiella pneumoniae is a frequent cause of infectious outbreaks in Neonatal Intensive Care Units (NICUs). The aim of this paper is to describe an outbreak occurred in a 13-bed NICU and the control measures adopted in order to interrupt the chain of...

(This article belongs to the Special Issue Antimicrobial Resistance Prevention and Control)
  • Review
  • Open Access
13 Citations
7,332 Views
19 Pages

Pressure Injury Prediction in Intensive Care Units Using Artificial Intelligence: A Scoping Review

  • José Alves,
  • Rita Azevedo,
  • Ana Marques,
  • Rúben Encarnação and
  • Paulo Alves

Background/Objetives: Pressure injuries pose a significant challenge in healthcare, adversely impacting individuals’ quality of life and healthcare systems, particularly in intensive care units. The effective identification of at-risk individua...

(This article belongs to the Section Artificial Intelligence and Digital Innovations in Nursing Care)
  • Review
  • Open Access
1 Citations
3,308 Views
15 Pages

29 September 2025

Background: Psychological and spiritual support is crucial, especially in challenging life situations, trials, and when facing the unimaginable distress experienced by parents of premature babies in the intensive care unit. This scoping review aims t...

(This article belongs to the Section Mental Health and Psychosocial Well-being)
  • Article
  • Open Access
14 Citations
4,162 Views
15 Pages

Impact of Candida auris on Critically Ill Patients: A Three-Year Observational Study in a Greek Intensive Care Unit

  • Maria Katsiari,
  • Charikleia Nikolaou,
  • Eleftheria Palla,
  • Kalliopi Theodoridou and ,
  • Athanasios Tsakris and
  • Georgia Vrioni
  • + 1 author+ 0 author

Candida auris has emerged as a multidrug-resistant yeast implicated in healthcare-associated invasive infections and hospital outbreaks. The aim of the current 38-month period observational study in a multidisciplinary Intensive Care Unit (ICU) was t...

  • Article
  • Open Access
625 Views
9 Pages

Long-Term Functional Outcomes After Pediatric Intensive Care Unit Admission for Bronchiolitis: A 12-Month Cohort Study

  • Paula Sevilla Hermoso,
  • Mireia Mor Conejo,
  • Carme Alejandre,
  • Laia Roig Cortes and ,
  • Omar Rodriguez,
  • Francisco José Cambra Lasaosa,
  • Iolanda Jordan and
  • Mònica Balaguer
  • + 3 authors+ 0 author

Introduction. Bronchiolitis is the leading cause of Pediatric Intensive Care Unit (PICU) admission for lower respiratory tract infection in infants. Although survival has improved, concerns remain regarding potential long-term functional impairments,...

(This article belongs to the Special Issue Application of Extracorporeal Life Support in Pediatric Critical Care)
  • Article
  • Open Access
3 Citations
1,632 Views
17 Pages

High Prevalence of Malnutrition and Sarcopenia with Inadequate Nutritional Support in Intensive Care Unit Patients: A Prospective Observational Study of Clinical Outcomes

  • Rym Ben Othman,
  • Asma Cherni,
  • Ismail Dergaa,
  • Halil İbrahim Ceylan and ,
  • Nagihan Burçak Ceylan,
  • Valentina Stefanica,
  • Ines Sedghiani,
  • Nebiha Borsali and
  • Henda Jamoussi
  • + 4 authors+ 0 author

10 March 2026

Background: Malnutrition and sarcopenia are highly prevalent in intensive care settings and are associated with adverse clinical outcomes. Aim: The study aimed to evaluate the association between nutritional care, nutritional status, and patient outc...

(This article belongs to the Special Issue Nutritional Support for Critically Ill Patients)
  • Review
  • Open Access
19 Citations
7,014 Views
16 Pages

Bedside Ultrasound for Hemodynamic Monitoring in Cardiac Intensive Care Unit

  • Maria Concetta Pastore,
  • Federica Ilardi,
  • Andrea Stefanini,
  • Giulia Elena Mandoli and ,
  • Stefano Palermi,
  • Francesco Bandera,
  • Giovanni Benfari,
  • Roberta Esposito,
  • Matteo Lisi and
  • Matteo Cameli
  • + 9 authors+ 4 authors

19 December 2022

Thanks to the advances in medical therapy and assist devices, the management of patients hospitalized in cardiac intensive care unit (CICU) is becoming increasingly challenging. In fact, Patients in the cardiac intensive care unit are frequently char...

(This article belongs to the Collection The Development and Application of Echocardiography in Heart Disease)
  • Article
  • Open Access
5 Citations
2,561 Views
14 Pages

27 March 2025

Objectives: To describe the strengths and barriers of administering a physiotherapy treatment to patients admitted to an intensive care unit. Methods: Qualitative interpretative description study. Twenty-one health professionals working in an intensi...

(This article belongs to the Special Issue Physical Therapy in Musculoskeletal Disorders: Prevention, Diagnosis, Clinical Management and Treatment)
  • Article
  • Open Access
19 Citations
3,328 Views
12 Pages

Incidence and Risk Factors of COVID-19-Associated Pulmonary Aspergillosis in Intensive Care Unit—A Monocentric Retrospective Observational Study

  • Emilien Gregoire,
  • Benoit François Pirotte,
  • Filip Moerman,
  • Antoine Altdorfer and ,
  • Laura Gaspard,
  • Eric Firre,
  • Martial Moonen,
  • Vincent Fraipont,
  • Marie Ernst and
  • Gilles Darcis
  • + 5 authors+ 0 author

22 October 2021

Coronavirus disease 2019 (COVID-19)-associated pulmonary aspergillosis (CAPA) is an increasingly recognized complication of COVID-19 and is associated with significant over-mortality. We performed a retrospective monocentric study in patients admitte...

(This article belongs to the Special Issue Aspergillosis)
  • Article
  • Open Access
581 Views
16 Pages

Background: Clinical deterioration is common among patients hospitalized in Internal Medicine wards and frequently results in the need for Intensive Care Unit (ICU) admission. Limited ICU bed capacity may lead to delays or interhospital transfers, po...

(This article belongs to the Section Healthcare Organizations, Systems, and Providers)
  • Article
  • Open Access
5 Citations
6,100 Views
12 Pages

The Impact of Delayed Symptomatic Treatment Implementation in the Intensive Care Unit

  • Lesley Meng,
  • Krzysztof Laudanski,
  • Mariana Restrepo,
  • Ann Huffenberger and
  • Christian Terwiesch

25 December 2021

We estimated the harm related to medication delivery delays across 12,474 medication administration instances in an intensive care unit using retrospective data in a large urban academic medical center between 2012 and 2015. We leveraged an instrumen...

(This article belongs to the Special Issue Anesthesiology and Critical Care)
  • Review
  • Open Access
2 Citations
4,979 Views
19 Pages

Point-of-Care Lung Ultrasound in the Intensive Care Unit—The Dark Side of Radiology: Where Do We Stand?

  • Marco Di Serafino,
  • Giuseppina Dell’Aversano Orabona,
  • Martina Caruso,
  • Costanza Camillo and ,
  • Daniela Viscardi,
  • Francesca Iacobellis,
  • Roberto Ronza,
  • Vittorio Sabatino,
  • Luigi Barbuto and
  • Luigia Romano
  • + 6 authors+ 1 author

26 October 2023

Patients in intensive care units (ICUs) are critically ill and require constant monitoring of clinical conditions. Due to the severity of the underlying disease and the need to monitor devices, imaging plays a crucial role in critically ill patients&...

(This article belongs to the Special Issue Emergency Medicine: Clinical Advances and Challenges in Diagnosis and Treatment)
  • Article
  • Open Access
38 Citations
6,826 Views
17 Pages

Impact of HVAC-Systems on the Dispersion of Infectious Aerosols in a Cardiac Intensive Care Unit

  • Larisa Anghel,
  • Cătălin-George Popovici,
  • Cristian Stătescu,
  • Radu Sascău and ,
  • Marina Verdeș,
  • Vasilică Ciocan,
  • Ionela-Lăcrămioara Șerban,
  • Minela Aida Mărănducă,
  • Sebastian-Valeriu Hudișteanu and
  • Florin-Emilian Țurcanu
  • + 5 authors+ 0 author

At the end of 2019, a variation of a coronavirus, named SARS-CoV-2, has been identified as being responsible for a respiratory illness disease (COVID-19). Since ventilation is an important factor that influences airborne transmission, we proposed to...

(This article belongs to the Special Issue Air Pollution & COVID-19 Outbreak)
  • Article
  • Open Access
19 Citations
3,398 Views
11 Pages

Impact of the COVID-19 Pandemic on Epidemiology of Antibiotic Resistance in an Intensive Care Unit (ICU): The Experience of a North-West Italian Center

  • Andrea Parisini,
  • Silvia Boni,
  • Elisabetta Blasi Vacca,
  • Nicoletta Bobbio and ,
  • Filippo Del Puente,
  • Marcello Feasi,
  • Roberta Prinapori,
  • Marco Lattuada,
  • Marina Sartini and
  • Emanuele Pontali
  • + 7 authors+ 2 authors

The SARS-CoV-2 pandemic caused an increase in intensive care unit (ICU) hospitalizations with a rise in morbidity and mortality; nevertheless, there is still little evidence on the impact of the pandemic on antibiotic resistance in ICUs. This is a re...

(This article belongs to the Special Issue Antimicrobial Resistance during the COVID-19 Outbreak)
  • Article
  • Open Access
27 Citations
6,688 Views
9 Pages

Risk Factors of Eye Complications in Patients Treated in the Intensive Care Unit

  • Lucyna Płaszewska-Żywko,
  • Aurelia Sega,
  • Agnieszka Bukowa,
  • Katarzyna Wojnar-Gruszka and ,
  • Marcelina Podstawa and
  • Maria Kózka
  • + 1 author+ 0 author

In critically ill patients, normal eye protection mechanisms, such as tear production, blinking, and keeping the eye closed, are impaired. In addition, many other factors related to patients’ severe condition and treatment contribute to ocular surfac...

(This article belongs to the Special Issue Intensive and Critical Care Nursing Research)
  • Article
  • Open Access
22 Citations
4,362 Views
12 Pages

Emergence of Clonally-Related South Asian Clade I Clinical Isolates of Candida auris in a Greek COVID-19 Intensive Care Unit

  • Maria Katsiari,
  • Angeliki Mavroidi,
  • Nikolaos Kesesidis,
  • Eleftheria Palla and ,
  • Konstantina Zourla,
  • Kyriakos Ntorlis,
  • Konstantinos Konstantinidis,
  • Maria Laskou,
  • Konstantinos Strigklis and
  • Athanasios Tsakris
  • + 10 authors+ 5 authors

11 February 2023

Candida auris has recently emerged as a multidrug-resistant yeast implicated in various healthcare-associated invasive infections and hospital outbreaks. In the current study, we report the first five intensive care unit (ICU) cases affected by C. au...

  • Review
  • Open Access
14 Citations
6,005 Views
13 Pages

Neuromuscular Ultrasound in Intensive Care Unit-Acquired Weakness: Current State and Future Directions

  • Felix Klawitter,
  • Uwe Walter,
  • Hubertus Axer,
  • Robert Patejdl and
  • Johannes Ehler

27 April 2023

Intensive care unit-acquired weakness (ICUAW) is one of the most common causes of muscle atrophy and functional disability in critically ill intensive care patients. Clinical examination, manual muscle strength testing and monitoring are frequently h...

(This article belongs to the Special Issue Current and Future Applications of Ultrasound Imaging in Peripheral Nerve and Muscle Disorders)

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