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  • Article
  • Open Access
6 Citations
5,367 Views
22 Pages

Exploring Beneficial Properties of Haskap Berry Leaf Compounds for Gut Health Enhancement

  • Szymon Sip,
  • Anna Sip,
  • Piotr Szulc,
  • Marek Selwet and ,
  • Marcin Żarowski,
  • Bogusław Czerny and
  • Judyta Cielecka-Piontek
  • + 2 authors+ 0 author

This study investigates the potential of formulated systems utilising haskap berry leaf extracts and dextran as carriers, to modulate both antioxidant and enzymatic inhibitory activities and their impact on the growth of specific bacterial strains. T...

  • Article
  • Open Access
8 Citations
3,289 Views
19 Pages

Haskap Berry Phenolic Subclasses Differentially Impact Cellular Stress Sensing in Primary and Immortalized Dermal Fibroblasts

  • Lily R. Zehfus,
  • Zoe E. Gillespie,
  • Carla Almendáriz-Palacios,
  • Nicholas H. Low and
  • Christopher H. Eskiw

3 October 2021

It is generally accepted that dietary phenolics from fruits are of significant importance to human health. Unfortunately, there is minimal published data on how differences in phenolic structure(s) impact biological pathways at cellular and molecular...

  • Article
  • Open Access
413 Views
12 Pages

NIR Spectroscopy for Predicting Physicochemical and Functional Quality Attributes of Berry (Aronia, Haskap, and Goji) Fruits

  • Juan Carlos Solomando,
  • Patricia Calvo,
  • María José Rodríguez,
  • Noelia Nicolás and ,
  • María Ramos,
  • Lucía León and
  • Alberto Ortiz
  • + 2 authors+ 0 author

29 July 2026

This study evaluated the potential of a miniaturized portable near-infrared spectroscopy (NIRS) device for the non-destructive prediction of the physicochemical and functional quality attributes of red berries. A total of 145 samples from three berry...

(This article belongs to the Section Food Quality and Safety)
  • Article
  • Open Access
10 Citations
5,280 Views
18 Pages

Comparative Evaluation of the Phytochemical Composition of Fruits of Ten Haskap Berry (Lonicera caerulea var. kamtschatica Sevast.) Cultivars Grown in Poland

  • Natalia Żurek,
  • Stanisław Pluta,
  • Łukasz Seliga,
  • Sabina Lachowicz-Wiśniewska and
  • Ireneusz Tomasz Kapusta

1 October 2024

The aim of this study was to investigate the qualitative and quantitative fruit profiles of ten cultivars (cvs.) of haskap berry (Lonicera caerulea var. kamtschatica Sevast.) to determine their antioxidant activity (ABTS test, CUPRAC test, ability to...

(This article belongs to the Section Agricultural Product Quality and Safety)
  • Article
  • Open Access
6 Citations
2,296 Views
23 Pages

Bioactive Compounds and In Vitro Health-Promoting Activity of the Fruit Skin and Flesh of Different Haskap Berry (Lonicera caerulea var. kamtschatica Sevast.) Cultivars

  • Natalia Żurek,
  • Stanisław Pluta,
  • Michał Świeca,
  • Leszek Potocki and ,
  • Łukasz Seliga and
  • Ireneusz Kapusta
  • + 1 author+ 0 author

The study focused on the distribution of polyphenolic compounds, iridoids, organic acids, and sugars, as well as in vitro antioxidant, anti-inflammatory, antidiabetic, antiproliferation, and antibacterial potential, and physicochemical properties bet...

(This article belongs to the Special Issue Plant-Derived Food Products in the Prevention of Chronic Non-Communicable Diseases)
  • Article
  • Open Access
16 Citations
3,531 Views
12 Pages

Kamchatka berry (Lonicera caerulea var. kamtschatica) and haskap (Lonicera caerulea var. emphyllocalyx) fruit are important sources of bioactive compounds, mainly polyphenols, but also macro- and microelements. Physico-chemical analysis showed that w...

(This article belongs to the Special Issue Nutrition and Sensory Analysis of Food)
  • Article
  • Open Access
18 Citations
5,588 Views
17 Pages

Haskap Berry Leaves (Lonicera caerulea L.)—The Favorable Potential of Medical Use

  • Szymon Sip,
  • Anna Sip,
  • Piotr Szulc and
  • Judyta Cielecka-Piontek

21 September 2022

The presented research evaluates the medical use potential of Lonicera caerulea leaves, which are waste plants in cultivating berries. The study’s screening activity included the leaves of five varieties of Lonicera caerulea: Atut, Duet, Wojtek...

(This article belongs to the Special Issue Potential Sources of Novel Foods to Procure Nutrients and Bioactive Compounds for Disease Prevention)
  • Article
  • Open Access
3 Citations
1,452 Views
21 Pages

17 February 2025

It is well established that phenolic compounds from plant sources impact readouts of cell health such as reduced radical and reactive oxygen species. However, it is unclear if specific phenolic structures impact other cellular processes or proteins,...

(This article belongs to the Section Cellular Aging)
  • Article
  • Open Access
9 Citations
2,953 Views
16 Pages

26 February 2025

Haskap (Lonicera caerulea) berry is rich in anthocyanins, particularly cyanidin-3-O-glucoside (C3G). In this investigation, a response surface methodology was applied to optimize the anhydrous ethanol-based extraction parameters to obtain the maximum...

(This article belongs to the Special Issue Exploring Bioactive Polyphenolic Compounds in Food and Natural Real-World Samples II)
  • Article
  • Open Access
19 Citations
14,444 Views
13 Pages

Improved Endurance Running Performance Following Haskap Berry (Lonicera caerulea L.) Ingestion

  • Glyn Howatson,
  • Gemma C. Snaith,
  • Rachel Kimble,
  • Gavin Cowper and
  • Karen M. Keane

13 February 2022

Background: Food high in (poly)phenolic compounds, such as anthocyanins, have the potential to improve exercise recovery and exercise performance. Haskap berries are rich in anthocyanins, but no research has examined the potential to improve human pe...

(This article belongs to the Section Sports Nutrition)
  • Article
  • Open Access
6 Citations
3,063 Views
15 Pages

Characterization and Classification of Berry (Aronia, Haskap, and Goji) Fruits with High Bioactive Value Grown in Spain

  • María Concepción Ayuso-Yuste,
  • Francisco Javier Cruz Calero,
  • María Ramos García,
  • Noelia Nicolás Barroso and ,
  • María Belén Ramos Alguijo,
  • María José Rodríguez Gómez and
  • Patricia Calvo Magro
  • + 2 authors+ 0 author

20 December 2024

Aronia, haskap, and goji berries are characterized by their high content of bioactive compounds and their beneficial health properties as well as their resistance to harsh agronomic conditions. In this work, cultivars of these species growing in a mo...

(This article belongs to the Section Plant Foods)
  • Article
  • Open Access
5 Citations
1,826 Views
21 Pages

Physicochemical Properties and Quality of Bread Enriched with Haskap Berry (Lonicera caerulea L.) Pomace

  • Grażyna Cacak-Pietrzak,
  • Agata Marzec,
  • Kacper Onisk,
  • Stanisław Kalisz and ,
  • Wioleta Dołomisiewicz,
  • Renata Nowak,
  • Anna Krajewska and
  • Dariusz Dziki
  • + 3 authors+ 0 author

25 September 2025

Haskap berry (Lonicera caerulea L.) pomace, a by-product of juice processing, is a rich source of bioactive compounds. The aim of this study was to evaluate the effect of incorporating lyophilized and ground haskap berry pomace on the physicochemical...

(This article belongs to the Section Food Chemistry)
  • Article
  • Open Access
32 Citations
5,058 Views
13 Pages

22 August 2020

In our previous study, we demonstrated that cyanidin-3-O-glucoside (C3G)-rich haskap (Lonicera caerulea L.) berry extracts can attenuate the carcinogen-induced DNA damage in normal lung epithelial cells in vitro. Here, the efficacy of lyophilized pow...

(This article belongs to the Special Issue Flavonoids and Their Disease Prevention and Treatment Potential)
  • Article
  • Open Access
5 Citations
3,377 Views
25 Pages

24 June 2024

Haskap berry (Lonicera caerulea L.) is a rich dietary source of anthocyanins with potent anti-inflammatory properties. In this study, isolated haskap berry anthocyanins were encapsulated in maltodextrin and inulin (3:1) by freeze-drying to improve st...

(This article belongs to the Special Issue The Health Benefits of Food-Derived Bioactive Ingredients)
  • Article
  • Open Access
41 Citations
7,942 Views
13 Pages

27 January 2018

Cyanidin-3-O-glucoside (C3G), the predominant anthocyanin in haskap berries (Lonicera caerulea L.), possesses antioxidant and many other biological activities. This study investigated the impact of temperature and pH on the degradation of the C3G-ric...

(This article belongs to the Special Issue Feature Papers in Antioxidants in 2018)
  • Article
  • Open Access
2 Citations
2,382 Views
23 Pages

Suppression of NNK Metabolism by Anthocyanin-Rich Haskap Berry Supplementation Through Modulation of P450 Enzymes

  • Madumani Amararathna,
  • David W. Hoskin,
  • Kerry B. Goralski and
  • H. P. Vasantha Rupasinghe

30 November 2024

Oral supplementation of anthocyanins-rich haskap (Lonicera caerulea) berry (HB) reduces 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)-induced lung tumorigenesis, cytotoxicity, DNA damage, and modulated inflammation in vitro and in vivo. The pr...

(This article belongs to the Special Issue Bioactive Substances, Oxidative Stress, and Inflammation)
  • Article
  • Open Access
5 Citations
4,159 Views
17 Pages

This article focuses on analysing the properties of six varieties of haskap berry (honeyberry) as a valuable raw material for producing health-promoting juices. Significant differences in the content of bioactive compounds were observed between juice...

(This article belongs to the Special Issue The Impact of Environmental Factors on the Quality of Horticultural Commodities)
  • Article
  • Open Access
2 Citations
1,559 Views
26 Pages

Ultrasound Treatment in Berry Puree Production: Effects on Sensory, Rheological, and Chemical Properties

  • Jan Piecko,
  • Monika Mieszczakowska-Frąc,
  • Niall J. Dickinson,
  • Anna Wrzodak and ,
  • Karolina Celejewska,
  • Michael Bom Frøst,
  • Belinda Lange,
  • Charlotte Dandanell,
  • Jacek Lewandowicz and
  • Patrycja Jankowska
  • + 5 authors+ 0 author

12 January 2026

Berries are a valuable source of health-promoting substances, including vitamins, microelements, and polyphenols. Optimising the extraction efficiency of these compounds during processing is crucial to minimise their loss into the waste stream. Ultra...

(This article belongs to the Special Issue Advances in Physicochemical Properties of Innovative Food Products During Processing)
  • Article
  • Open Access
22 Citations
3,385 Views
18 Pages

The Chemical Profile, Antioxidant, and Anti-Lipid Droplet Activity of Fluid Extracts from Romanian Cultivars of Haskap Berries, Bitter Cherries, and Red Grape Pomace for the Management of Liver Steatosis

  • Oana Craciunescu,
  • Ana-Maria Seciu-Grama,
  • Elena Mihai,
  • Elena Utoiu and ,
  • Ticuta Negreanu-Pirjol,
  • Carmen Elena Lupu,
  • Victoria Artem,
  • Aurora Ranca and
  • Bogdan-Stefan Negreanu-Pirjol
  • + 4 authors+ 0 author

28 November 2023

This study aimed to investigate, for the first time, the chemical composition and antioxidant activity of fluid extracts obtained from three Romanian cultivars of haskap berries (Lonicera caerulea L.) var. Loni, bitter cherries (Prunus avium var. syl...

(This article belongs to the Special Issue Natural Bioactives and Inflammation)
  • Article
  • Open Access
1 Citations
1,841 Views
15 Pages

Effects of Growth Stages on Leaf Nutrients, Metabolites, and Polyphenols of Three Varieties of Haskap

  • Chijioke Emenike,
  • Shakirah Azeez,
  • Marcia English,
  • Chibuike Udenigwe and
  • Lord Abbey

24 November 2024

Haskap (Lonicera caerulea L.) has gained much research interest, given the diverse biologically active compounds found in different parts of the plant. It is, therefore, important to study the concentration of some of these biologically active compou...

(This article belongs to the Section Food Nutrition)
  • Article
  • Open Access
13 Citations
2,938 Views
20 Pages

Advantages of Spray Drying over Freeze Drying: A Comparative Analysis of Lonicera caerulea L. Juice Powders—Matrix Diversity and Bioactive Response

  • Anna Michalska-Ciechanowska,
  • Jessica Brzezowska,
  • Paulina Nowicka,
  • Karolina Tkacz and ,
  • Igor Piotr Turkiewicz,
  • Aleksandra Hendrysiak,
  • Jan Oszmiański and
  • Wilfried Andlauer
  • + 3 authors+ 0 author

30 July 2024

The study investigated the impact of Lonicera caerulea L. juice matrix modification and drying techniques on powder characteristics. The evaluation encompassed phenolics (514.7–4388.7 mg/100 g dry matter), iridoids (up to 337.5 mg/100 g dry mat...

(This article belongs to the Section Food Chemistry)
  • Article
  • Open Access
550 Views
29 Pages

14 May 2026

Continuous-flow microwave (MW) pasteurization is a relatively new and still poorly understood preservation method with great potential for industrial applications. The raw material for the research was blue honeysuckle berries (Lonicera caerulea var....

(This article belongs to the Special Issue Application and Extraction of Bioactive Compounds and Antioxidants in Food and Plants)
  • Article
  • Open Access
91 Citations
13,890 Views
20 Pages

Anti-Inflammatory Activity of Haskap Cultivars is Polyphenols-Dependent

  • H. P. Vasantha Rupasinghe,
  • Mannfred M. A. Boehm,
  • Satvir Sekhon-Loodu,
  • Indu Parmar and ,
  • Bob Bors and
  • Andrew R. Jamieson
  • + 1 author+ 0 author

2 June 2015

Haskap (Lonicera caerulea L.) berries have long been used for their health promoting properties against chronic conditions. The current study investigated the effect of Canadian haskap berry extracts on pro-inflammatory cytokines using a human monocy...

(This article belongs to the Special Issue Oxidative Stress and Oxygen Radicals)
  • Review
  • Open Access
10 Citations
4,666 Views
27 Pages

Blueberries and Honeysuckle Berries: Anthocyanin-Rich Polyphenols for Vascular Endothelial Health and Cardiovascular Disease Prevention

  • Sanda Jurja,
  • Ticuta Negreanu-Pirjol,
  • Mihaela-Cezarina Mehedinți,
  • Maria-Andrada Hincu and ,
  • Bogdan-Stefan Negreanu-Pirjol,
  • Florentina-Nicoleta Roncea and
  • Alin Laurențiu Tatu
  • + 2 authors+ 0 author

12 December 2025

Cardiovascular disease remains the world’s leading cause of death globally, and there is continuing interest in adjunct, diet-based strategies that may support vascular health alongside guideline-directed pharmacotherapy. Anthocyanin-rich berri...

(This article belongs to the Special Issue The Role of Bioactive Compounds in Human Health and Diseases (3rd Edition))
  • Article
  • Open Access
55 Citations
7,109 Views
18 Pages

Promising Antioxidant and Antimicrobial Food Colourants from Lonicera caerulea L. var. Kamtschatica

  • Adriana K. Molina,
  • Erika N. Vega,
  • Carla Pereira,
  • Maria Inês Dias and ,
  • Sandrina A. Heleno,
  • Paula Rodrigues,
  • Isabel P. Fernandes,
  • Maria Filomena Barreiro,
  • Marina Kostić and
  • Isabel C.F.R. Ferreira
  • + 8 authors+ 3 authors

12 September 2019

Lonicera caerulea L. (haskap) berries are widely known for their richness in anthocyanins. In this study, such fruits were assessed for their nutritional and chemical composition, but also as sources of anthocyanins with great colouring properties to...

(This article belongs to the Special Issue Antioxidant Properties of Natural Products: A Themed Issue in Honor of Professor Isabel C.F.R. Ferreira)
  • Article
  • Open Access
20 Citations
3,679 Views
17 Pages

13 September 2024

The goal of the research was to determine the impact of fortification with polyphenolic compounds on (i) sensory attractiveness (global satisfaction, appearance, colour, odour, flavour, sweetness, bitterness), (ii) content of polyphenols and colour (...

(This article belongs to the Section Natural and Synthetic Antioxidants)
  • Review
  • Open Access
107 Citations
14,269 Views
14 Pages

9 February 2020

Lonicera caerulea L., also known as haskap or honeysuckle berry, is a fruit commonly planted in eastern Europe, Canada and Asia. The fruit was registered as a traditional food from a third country under European Union regulations only on December 201...

  • Review
  • Open Access
8 Citations
5,314 Views
26 Pages

A Systematic Review of Cardio-Metabolic Properties of Lonicera caerulea L.

  • Larisa Bora,
  • Adelina Lombrea,
  • Stefan Laurentiu Batrina,
  • Valentina Oana Buda and ,
  • Oana-Maria Esanu,
  • Oana Pasca,
  • Cristina Adriana Dehelean,
  • Stefania Dinu,
  • Zorita Diaconeasa and
  • Corina Danciu
  • + 5 authors+ 0 author

In the light of growing concerns faced by Western societies due to aging, natality decline, and epidemic of cardio-metabolic diseases, both preventable and treatable, new and effective strategical interventions are urgently needed in order to decreas...

(This article belongs to the Special Issue Potential Health Benefits of Dietary Antioxidants)
  • Article
  • Open Access
24 Citations
5,060 Views
13 Pages

Phytochemical Characterization of Blue Honeysuckle in Relation to the Genotypic Diversity of Lonicera sp.

  • Jacek Gawroński,
  • Jadwiga Żebrowska,
  • Marzena Pabich,
  • Izabella Jackowska and ,
  • Krzysztof Kowalczyk and
  • Magdalena Dyduch-Siemińska
  • + 1 author+ 0 author

18 September 2020

The phytochemical characteristic analysis of a group of 30 haskap berry genotypes was carried out bearing in mind the concern for the consumption of food with high nutraceutical value that helps maintain good health. Phytochemical fruit composition a...

(This article belongs to the Special Issue Potential Health Benefits of Fruits and Vegetables)
  • Article
  • Open Access
51 Citations
7,732 Views
14 Pages

Preparative Purification of Polyphenols from Aronia melanocarpa (Chokeberry) with Cellular Antioxidant and Antiproliferative Activity

  • Ningxuan Gao,
  • Yuehua Wang,
  • Xinyao Jiao,
  • Shurui Chou and ,
  • Enhui Li and
  • Bin Li
  • + 1 author+ 0 author

10 January 2018

The aim of this study was the purification process of polyphenols from Aronia melanocarpa (chokeberry), and the purification parameters were optimised by adsorption and desorption tests. By comparing adsorption and desorption ability of polyphenols f...

(This article belongs to the Special Issue Selected Papers from the 6th International Conference on Biotechnology and Bioengineering (6-ICBB 2017))
  • Article
  • Open Access
11 Citations
2,981 Views
22 Pages

This study aimed to develop innovative fruit leather with programmed health-promoting properties, enriched with fructooligosaccharides (FOS) from chicory and Jerusalem artichoke. Their physicochemical properties were assessed, including the profile o...

(This article belongs to the Special Issue Functional Foods Enriched with Natural Bioactive Compounds)
  • Article
  • Open Access
357 Views
41 Pages

14 September 2026

The growing demand for dairy-free functional foods has created a need for fruit-based products that simultaneously provide probiotics, prebiotics, and bioactive compounds. This study evaluated seven high-fruit synbiotic-designed sorbets prepared with...

(This article belongs to the Special Issue Innovative Directions in the Development of Functional Food)