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Functional Foods Enriched with Natural Bioactive Compounds

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Natural Products Chemistry".

Deadline for manuscript submissions: 30 June 2026 | Viewed by 3309

Special Issue Editor


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Guest Editor
1. Department of Chemistry and Biodynamics of Food, Institute of Animal Reproduction and Food Research of Polish Academy of Sciences, 10-748 Olsztyn, Poland
2. Institute of Food Technology of Plant Origin, Poznań University of Life Sciences, 31 Wojska Polskiego Street, 60-624 Poznań, Poland
Interests: food science and nutrition; food chemistry; bioactive compounds; nutritional interventions; clinical trials; volatile organic compounds; gas chromatography-mass spectrometry
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Special Issue Information

Dear Colleagues,

Functional foods offer health benefits that extend beyond basic nutrition. These foods are often enriched with additional nutrients or contain bioactive compounds that can enhance health and reduce the risk of disease. Natural bioactive compounds, found in plants, animals, and other organisms, exhibit biological activity in the body. Compounds such as flavonoids, polyphenols, and carotenoids provide various health benefits, including antioxidant, anti-inflammatory, and antimicrobial effects. They are crucial in protecting cells from damage, supporting the immune system, and lowering the risk of chronic diseases like heart disease and cancer.

The growing interest in developing new functional foods and products fortified with bioactive compounds from natural sources underscores the importance of this field. Utilizing by-products that still contain bioactive compounds can not only improve the taste and properties of food products but also reduce the environmental burden of waste.

This Special Issue aims to cover a broad range of topics, including the development of new functional products, quality assessment of fortified products, sensory analysis of functional foods, chemical composition of natural ingredients, valorization of by-products, long-term health effects of consuming functional foods, the bioavailability of bioactive compounds, and the economic feasibility of large-scale production.

Dr. Natalia Drabińska
Guest Editor

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Keywords

  • functional food
  • bioactive compounds
  • phytochemicals
  • fortification
  • valorization
  • by-products
  • polyphenols
  • glucosinolates
  • gluten-free
  • probiotics
  • prebiotics
  • health benefits
  • sensory analysis
  • bioavailability

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Published Papers (2 papers)

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Research

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22 pages, 874 KB  
Article
Functional Fruit Snacks Enriched with Natural Sources of Fructooligosaccharides: Composition, Bioactive Compounds, Biological Activity, and Consumer Acceptance
by Paulina Nowicka, Michalina Marcińczak, Martyna Szydłowska and Aneta Wojdyło
Molecules 2025, 30(12), 2507; https://doi.org/10.3390/molecules30122507 - 7 Jun 2025
Cited by 1 | Viewed by 1520
Abstract
This study aimed to develop innovative fruit leather with programmed health-promoting properties, enriched with fructooligosaccharides (FOS) from chicory and Jerusalem artichoke. Their physicochemical properties were assessed, including the profile of polyphenolic compounds, pro-health effects, and sensory characteristics. The products contained various fruits (including [...] Read more.
This study aimed to develop innovative fruit leather with programmed health-promoting properties, enriched with fructooligosaccharides (FOS) from chicory and Jerusalem artichoke. Their physicochemical properties were assessed, including the profile of polyphenolic compounds, pro-health effects, and sensory characteristics. The products contained various fruits (including pear, red currant, peach, and haskap berry) and 10% FOS powders. It was shown that the addition of FOS reduced acidity and total sugar content while increasing fiber content—especially fructans—and selected minerals (K, Mg, Zn). The addition of FOS also modulated the profile of polyphenolic compounds, whereas fruit leather without FOS was characterized by a higher concentration of these compounds. It was shown that the addition of chicory significantly modulates the ability to inhibit α-glucosidase. At the same time, in the case of the Jerusalem artichoke, the inhibition efficiency depends on the type of fruit matrix. Sensory-wise, the highest scores were given to recipes without FOS additives, with Jerusalem artichoke being better accepted than chicory. The results indicate the potential of using FOS as a functional additive, but their effects on taste and texture require further optimization. Full article
(This article belongs to the Special Issue Functional Foods Enriched with Natural Bioactive Compounds)
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Review

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26 pages, 1621 KB  
Review
Green Valorization Strategies of Pleurotus ostreatus and Its By-Products: A Critical Review of Emerging Technologies and Sustainable Applications
by Pablo Ayuso, Jhazmin Quizhpe, Rocío Peñalver, Pascual García-Pérez and Gema Nieto
Molecules 2025, 30(21), 4318; https://doi.org/10.3390/molecules30214318 - 6 Nov 2025
Viewed by 936
Abstract
Pleurotus ostreatus, commonly known as the oyster mushroom, is a widely cultivated edible mushroom characterized by its nutritional value and health benefits. However, its large-scale production generates significant amounts of agro-industrial by-products, such as stipes, residual mycelium, and spent mushroom substrate (SMS). [...] Read more.
Pleurotus ostreatus, commonly known as the oyster mushroom, is a widely cultivated edible mushroom characterized by its nutritional value and health benefits. However, its large-scale production generates significant amounts of agro-industrial by-products, such as stipes, residual mycelium, and spent mushroom substrate (SMS). These by-products are often discarded despite their high content of bioactive compounds such as dietary fiber, β-glucans, polyphenols, ergosterol, and essential minerals. This review provides a critical overview of emerging green extraction technologies (i.e., ultrasound-assisted extraction (UAE), microwave-assisted extraction (MAE), supercritical fluid extraction (SFE), subcritical water extraction (SWE), enzyme-assisted extraction (EAE), and pulsed electric fields (PEF)) as a strategy for the sustainable valorization of bioactive compounds from P. ostreatus by-products. Despite promising results in the extraction of β-glucans and phenolic compounds, industrial scalability remains a challenge due to cost, energy demand, and regulatory issues. In addition, the potential incorporation of these compound by-products into functional food formulations is explored, highlighting their possible applications in meat, bakery, and dairy products. Although notable outcomes have been obtained in the use of the fruiting body as a functional ingredient, further research is needed into the potential use of by-products in order to optimize processing parameters, ensure safety, and validate consumer acceptance. Overall, the sustainable valorization of P. ostreatus by-products represents a dual opportunity to reduce food waste and develop innovative functional ingredients that contribute to health and sustainability. Full article
(This article belongs to the Special Issue Functional Foods Enriched with Natural Bioactive Compounds)
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