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780 Results Found

  • Article
  • Open Access
1 Citations
3,525 Views
16 Pages

Effect of Foot Type on Plantar Pressure Distribution in Healthy Mexicans: Static and Dynamic Pressure Analysis

  • Jorge Armando Ramos-Frutos,
  • Diego Oliva,
  • Israel Miguel-Andres,
  • Didier Samayoa-Ochoa,
  • Jesús Salvador Jaime-Ferrer,
  • Luis Angel Ortiz-Lango and
  • Agustín Vidal Lesso

Background: Plantar pressure distribution is a valuable tool for studying how the ground reaction forces are transmitted from the feet to the body and for detecting abnormalities in foot biomechanics. Objectives: The objective of this study was to de...

  • Article
  • Open Access
2,477 Views
16 Pages

Iliotibial Band Behavior Assessed Through Tensor Fasciae Latae Electromyographic Activity with Different Foot Orthoses in Recreational Runners According to Foot Type: A Cross-Sectional Study

  • Ruben Sanchez-Gomez,
  • Álvaro Gómez Carrión,
  • Ismael Ortuño Soriano,
  • Paola Sanz Wozniak,
  • Ignacio Zaragoza García,
  • Fatma Ben Waer,
  • Cristina Iona Alexe and
  • Dan Iulian Alexe

Background: Iliotibial band syndrome (ITBS) through the tensor fascia latae (TFL) is a well-known pathology among runners whose etiology is not completely clear, nor is the effectiveness of plantar insoles for different types of feet known well enoug...

  • Article
  • Open Access
7 Citations
2,334 Views
15 Pages

Analysis of Circulating miRNA Expression Profiles in Type 2 Diabetes Patients with Diabetic Foot Complications

  • Giovanny Fuentevilla-Alvarez,
  • María Elena Soto,
  • Gustavo Jaziel Robles-Herrera,
  • Gilberto Vargas-Alarcón,
  • Reyna Sámano,
  • Sergio Enrique Meza-Toledo,
  • Claudia Huesca-Gómez and
  • Ricardo Gamboa

Type 2 diabetes mellitus (T2DM) is associated with various complications, including diabetic foot, which can lead to significant morbidity and mortality. Non-healing foot ulcers in diabetic patients are a major risk factor for infections and amputati...

  • Review
  • Open Access
6 Citations
6,683 Views
17 Pages

16 June 2023

Background: Despite the growing interest in golf, the impact of motion control strategy on golf performance may be uncertain. A network meta-analysis was conducted to investigate the relationships between ground reaction force (GRF), foot positions,...

  • Article
  • Open Access
9 Citations
4,805 Views
12 Pages

Development of Monoclonal Antibody Specific to Foot-and-Mouth Disease Virus Type A for Serodiagnosis

  • Quyen Thi Nguyen,
  • Jihyun Yang,
  • Jae-Won Byun,
  • Hyun Mi Pyo,
  • Mi-Young Park,
  • Bok Kyung Ku,
  • Jinju Nah,
  • Soyoon Ryoo,
  • Sung-Hwan Wee and
  • Haryoung Poo
  • + 1 author

17 December 2019

Foot-and-mouth disease (FMD) is a highly contagious and economically devastating disease affecting cloven-hoofed livestock worldwide. FMD virus (FMDV) type A is one of the most common causes of FMD outbreaks among the seven FMDV serotypes, and its se...

  • Article
  • Open Access
6 Citations
3,187 Views
12 Pages

Immunogenicity and Protection against Foot-and-Mouth Disease Virus in Swine Intradermally Vaccinated with a Bivalent Vaccine of Foot-and-Mouth Disease Virus Type O and A

  • Dong-Wan Kim,
  • Giyoun Cho,
  • Hyejin Kim,
  • Gyeongmin Lee,
  • Tae-Gwan Lim,
  • Ho-Young Kwak,
  • Jong-Hyeon Park and
  • Sung-Han Park

7 April 2023

Following the worst outbreak of foot-and-mouth disease (FMD), a highly contagious disease in cloven-hoofed animals caused by the FMD virus, from November 2010–April 2011, the Korean government enforced a mandatory vaccination policy. A bivalent...

  • Article
  • Open Access
731 Views
13 Pages

Long-Term Effect of a Structured Educational Program on Diabetic Foot on Major Adverse Limb and Cardiovascular Events in People with Type 1 Diabetes

  • Núria Alonso-Carril,
  • Maite Valverde,
  • Jordi Anglada,
  • Luis García-Pascual,
  • Maria-José Barahona,
  • Silvia Rodríguez-Rodríguez,
  • Belén Berrocal,
  • Carmen Quirós,
  • Andreu Simó-Servat and
  • Verónica Perea
  • + 4 authors

17 November 2025

Background/Objectives: To evaluate the long-term impact of a structured diabetic foot education program on major adverse limb events (MALEs) and major adverse cardiovascular events (MACEs) in individuals with type 1 diabetes. Methods: Retrospective c...

  • Article
  • Open Access
3 Citations
5,934 Views
14 Pages

Effect of Foot Reflexology on Muscle Electrical Activity, Pressure, Plantar Distribution, and Body Sway in Patients with Type 2 Diabetes Mellitus: A Pilot Randomized Controlled Trial

  • Thais Gebin Toledo,
  • Larissa Alves Moreira Freire,
  • Luciana Maria dos Reis,
  • Andréia Maria Silva Vilela Terra and
  • Adriana Teresa Silva Santos

Objective: To verify the effect of foot reflexology on the electrical muscle activity of the lateral and medial gastrocnemius muscle, and to examine the distribution, plantar pressure, and body sway in patients with type 2 diabetes mellitus. Methods:...

  • Article
  • Open Access
6 Citations
2,750 Views
14 Pages

Corneal Confocal Microscopy Predicts Cardiovascular and Cerebrovascular Events and Demonstrates Greater Peripheral Neuropathy in Patients with Type 1 Diabetes and Foot Ulcers

  • Jonathan Z. M. Lim,
  • Jamie Burgess,
  • Cheong Ooi,
  • Maryam Ferdousi,
  • Shazli Azmi,
  • Alise Kalteniece,
  • Matthew Anson,
  • Daniel J. Cuthbertson,
  • Ioannis N. Petropoulos and
  • Uazman Alam
  • + 2 authors

29 August 2023

Objective: In this study, we evaluate small and large nerve fibre pathology in relation to diabetic foot ulceration (DFU) and incident cardiovascular and cerebrovascular events in type 1 diabetes (T1D). Methods: A prospective observational study was...

  • Article
  • Open Access
3 Citations
5,029 Views
11 Pages

Foot Plantar Pressure Abnormalities in Near Adulthood Patients with Type 1 Diabetes

  • Marta Wysocka-Mincewicz,
  • Ewa Szczerbik,
  • Maria Mazur,
  • Magdalena Grabik,
  • Małgorzata Kalinowska and
  • Małgorzata Syczewska

Increased ulcer risk diminishes the quality of life in diabetes. This study assessed abnormalities in foot plantar pressure distribution in adolescents with T1D to detect early signs of ulcer risk. A total of 102 T1D patients, without diabetic neurop...

  • Article
  • Open Access
951 Views
15 Pages

26 November 2025

Background: Foot-and-mouth disease (FMD) is a highly contagious viral disease of cloven-hoofed animals such as cattle and pigs, characterized by vesicular lesions in the mouth, nose, teats, and feet. Globally, the most commonly used FMD vaccines are...

  • Article
  • Open Access
10 Citations
5,456 Views
12 Pages

Effects of Foot Structure Type on Core Stability in University Athletes

  • Orlando Santiago Moreno-Barriga,
  • Carlos Romero-Morales,
  • Ricardo Becerro-de-Bengoa-Vallejo,
  • Marta Elena Losa-Iglesias,
  • Juan Gómez-Salgado,
  • Julio Caballero-López,
  • Liz Carol Vidal-Valverde and
  • Daniel López-López

30 June 2023

Purpose: This study assessed the impact of different types of medial foot arch on postural stability and core center of gravity muscle activity among collegiate athletes. Methods: The study sample included 103 university-level athletes across various...

  • Article
  • Open Access
27 Citations
9,114 Views
19 Pages

11 August 2020

The human foot is easily deformed owing to the innate form of the foot or an incorrect walking posture. Foot deformations not only pose a threat to foot health but also cause fatigue and pain when walking; therefore, accurate diagnoses of foot deform...

  • Article
  • Open Access
12 Citations
3,717 Views
13 Pages

Overweight and Obesity: Its Impact on Foot Type, Flexibility, Foot Strength, Plantar Pressure and Stability in Children from 5 to 10 Years of Age: Descriptive Observational Study

  • Cristina Molina-García,
  • José Daniel Jiménez-García,
  • Daniel Velázquez-Díaz,
  • Laura Ramos-Petersen,
  • Andrés López-del-Amo-Lorente,
  • Carlos Martínez-Sebastián and
  • Francisco Álvarez-Salvago

7 April 2023

Background: Overweight (OW) and childhood obesity (OB) may cause foot problems and affect one’s ability to perform physical activities. The study aimed to analyze the differences in descriptive characteristics, foot type, laxity, foot strength,...

  • Case Report
  • Open Access
7,374 Views
8 Pages

Is the Small Ossicle of Type 1 Accessory Navicular a Cause of Foot Pain?—A Case Report

  • Takuji Yokoe,
  • Kazushi Uemichi,
  • Takuya Tajima and
  • Etsuo Chosa

28 August 2023

Background and objectives: An accessory navicular (AN) bone is often classified into types 1–3 according to the Veitch classification, and symptomatic type 1 patients usually receive non-surgical treatment. However, there are cases in which AN...

  • Article
  • Open Access
5 Citations
5,420 Views
13 Pages

Importance of Sock Type in the Development of Foot Lesions on Low-Difficulty, Short Hikes

  • Ana Mª Pérez Pico,
  • Ester Mingorance Álvarez,
  • Rodrigo Martínez Quintana and
  • Raquel Mayordomo Acevedo

Background and objectives: Foot lesions can be developed during hiking because of external factors. This makes it important to study the effect of hiking equipment on lesion development. Materials and Methods: Technical and non-technical socks were g...

  • Feature Paper
  • Article
  • Open Access
3 Citations
2,766 Views
15 Pages

The Effect of Neuropathy and Diabetes Type on Multisegment Foot Kinematics: A Cohort Study on 70 Participants with Diabetes

  • Paolo Caravaggi,
  • Claudia Giacomozzi,
  • Giada Lullini,
  • Giulio Marchesini,
  • Luca Baccolini,
  • Maurizio Ortolani,
  • Isabel C. N. Sacco,
  • Lisa Berti and
  • Alberto Leardini

23 September 2021

While lower limb biomechanics of people with diabetes are well described, the effects of diabetes type and of peripheral neuropathy on foot joint kinematics have not been addressed in depth. A total of 70 patients with type 1 (n = 25) and type 2 (n =...

  • Article
  • Open Access
2,412 Views
13 Pages

How Does Foot Arch Type Affect Gait Biomechanics in Patients with Plantar Fasciitis?

  • Seongok Chae,
  • Hyun Soo Kang,
  • Hojik Lee,
  • Yoo-Jin Jun,
  • SeungMyung Choi,
  • Young-Phil Yune and
  • Hyung-Soon Park

Plantar fasciitis (PFS) is a leading cause of heel pain, yet its clinical course varies widely. Although plantar fascia thickness (PFT) is often used as a pain marker, its prognostic value remains unclear. Objective: This study investigates whether f...

  • Article
  • Open Access
9 Citations
3,128 Views
10 Pages

Structural, Dermal and Ungual Characteristics of the Foot in Patients with Type II Diabetes

  • Cristina Gonzalez-Martin,
  • Sonia Pertega-Diaz,
  • Teresa Seoane-Pillado,
  • Vanesa Balboa-Barreiro,
  • Alfonso Soto-Gonzalez and
  • Raquel Veiga-Seijo

25 September 2019

Background and Objectives: Diabetes is a chronic and metabolic disease, considered as an important public health problem. The objective of this study was to determine the prevalence of podiatric pathology in type II diabetic patients. Materials and M...

  • Review
  • Open Access
4 Citations
6,005 Views
18 Pages

Review of Classification Systems for Adult Acquired Flatfoot Deformity/Progressive Collapsing Foot Deformity and the Novel Development of the Triple Classification Delinking Instability/Deformity/Reactivity and Foot Type

  • Chandra Seker Pasapula,
  • Makhib Rashid Choudkhuri,
  • Eva R. Gil Monzó,
  • Vivek Dhukaram,
  • Sajid Shariff,
  • Vitālijs Pasterse,
  • Douglas Richie,
  • Tamas Kobezda,
  • Georgios Solomou and
  • Steven Cutts

6 February 2024

Background: Classifications of AAFD/PCFD have evolved with an increased understanding of the pathology involved. A review of classification systems helps identify deficiencies and respective contributions to the evolution in understanding the classif...

  • Article
  • Open Access
3 Citations
2,614 Views
17 Pages

Descriptive Study of the Influence of Foot Type on Physical Characteristics, Laxity, Strength and Baropodometry in Children Aged 5 to 10 Years

  • Cristina Molina-García,
  • Francisco Álvarez-Salvago,
  • Clara Pujol-Fuentes,
  • Andrés López-del-Amo-Lorente,
  • Laura Ramos-Petersen,
  • Carlos Martínez-Sebastián,
  • Antonio Martínez-Amat,
  • José Daniel Jiménez-García and
  • Manuel De Diego-Moreno

24 September 2024

Background: Foot morphology in children is a crucial factor influencing multiple aspects of their physical development. Between the ages of 5 and 10 years, the critical period of child development is when the movement and stability patterns are conso...

  • Article
  • Open Access
8 Citations
4,097 Views
14 Pages

Foot Health Status Questionnaire (FHSQ) in Spanish People with Type 2 Diabetes Mellitus: Preliminary Values Study

  • Francisco Javier Domínguez-Muñoz,
  • Miguel Angel Garcia-Gordillo,
  • Rodrigo Anibal Diaz-Torres,
  • Miguel Ángel Hernandez-Mocholi,
  • Santos Villafaina,
  • Daniel Collado-Mateo,
  • Carmen Jiménez-Fernández,
  • Dimas Igual-Fraile,
  • Fernando Pérez-Escanilla and
  • Narcis Gusi
  • + 2 authors

Background and objectives: Type 2 Diabetes Mellitus (T2DM) is a chronic disease characterized by hyperglycemia. T2DM affects millions of people, and has a lot of complications such as impaired sensation in the feet. Moreover, it is important to know...

  • Article
  • Open Access
14 Citations
2,824 Views
9 Pages

Nutritional Status Assessed with Objective Data Assessment Correlates with a High-Risk Foot in Patients with Type 2 Diabetes

  • Yusuke Mineoka,
  • Michiyo Ishii,
  • Yoshitaka Hashimoto,
  • Aki Yamashita,
  • Takahiro Takemura,
  • Sachiyo Yamaguchi,
  • Machiko Toyoda and
  • Michiaki Fukui

27 February 2022

Malnutrition and diabetes are likely to co-occur. There are few reports on the association between nutritional status and foot risk in patients with type 2 diabetes (T2D). Therefore, we aimed to investigate this relationship in this cross-sectional s...

  • Article
  • Open Access
5 Citations
3,169 Views
18 Pages

Foot Position Measurement during Assistive Motion for Sit-to-Stand Using a Single Inertial Sensor and Shoe-Type Force Sensors

  • Kodai Kitagawa,
  • Ibai Gorordo Fernandez,
  • Takayuki Nagasaki,
  • Sota Nakano,
  • Mitsumasa Hida,
  • Shogo Okamatsu and
  • Chikamune Wada

Assistive motion for sit-to-stand causes lower back pain (LBP) among caregivers. Considering previous studies that showed that foot position adjustment could reduce lumbar load during assistive motion for sit-to-stand, quantitative monitoring of and...

  • Article
  • Open Access
15 Citations
4,667 Views
17 Pages

Inhibition of MAVS Aggregation-Mediated Type-I Interferon Signaling by Foot-and-Mouth Disease Virus VP3

  • Pathum Ekanayaka,
  • Byeong-Hoon Lee,
  • Asela Weerawardhana,
  • Kiramage Chathuranga,
  • Jong-Hyeon Park and
  • Jong-Soo Lee

6 September 2021

As a structural protein of the Foot-and-mouth disease virus (FMDV), VP3 plays a vital role in virus assembly and inhibiting the interferon (IFN) signal transduction to promote FMDV replication. Previous studies demonstrated that FMDV VP3 blocks the t...

  • Article
  • Open Access
4 Citations
3,059 Views
30 Pages

Host-Specific Interplay between Foot-and-Mouth Disease Virus 3D Polymerase and the Type-I Interferon Pathway

  • Morgan Sarry,
  • Grégory Caignard,
  • Juliette Dupré,
  • Stephan Zientara,
  • Damien Vitour,
  • Labib Bakkali Kassimi and
  • Sandra Blaise-Boisseau

1 March 2023

Foot-and-mouth disease (FMD) is a highly contagious viral disease affecting cloven-hoofed animals. One of the issues related to this disease is the persistence of its causative agent, foot-and-mouth disease virus (FMDV). While the mechanisms of FMDV...

  • Article
  • Open Access
11 Citations
2,885 Views
13 Pages

Cognitive Impairment in People with Diabetes-Related Foot Ulceration

  • Ranita Siru,
  • Melanie S. Burkhardt,
  • Wendy A. Davis,
  • Jonathan Hiew,
  • Laurens Manning,
  • Jens Carsten Ritter,
  • Paul E. Norman,
  • Ashley Makepeace,
  • Peter Gerry Fegan and
  • Emma J. Hamilton
  • + 2 authors

25 June 2021

Aims: To determine whether there is an excess of cognitive impairment in patients with type 2 diabetes and foot ulceration. Methods: 55 patients with type 2 diabetes and foot ulcers attending Multidisciplinary Diabetes Foot Ulcer clinics (MDFU cohort...

  • Article
  • Open Access
2 Citations
2,695 Views
12 Pages

Evaluation of a Vaccine Candidate Designed for Broad-Spectrum Protection against Type A Foot-and-Mouth Disease in Asia

  • Sung Ho Shin,
  • Seong Yun Hwang,
  • Hyun-Mi Kim,
  • Se Hee Shin,
  • Mi-Kyeong Ko,
  • Min Ja Lee,
  • Su-Mi Kim and
  • Jong-Hyeon Park

9 January 2024

Foot-and-mouth disease (FMD) vaccines are currently the most powerful protective and preventive measures used to control FMD. In this study, the chimeric vaccine strain containing antigenic epitopes from the FMD virus serotype A, which belongs to the...

  • Feature Paper
  • Article
  • Open Access
11 Citations
4,966 Views
9 Pages

Exploring the Relationship of Health Beliefs and Self-Care Behaviors Related to Diabetic Foot Ulcers of Type II Diabetes Mellitus Patients: A Cross-Sectional Study

  • Meng-Chien Tsai,
  • Hsiao-Ling Chuang,
  • Cheng-Yi Huang,
  • Shu-Hsin Lee,
  • Wen-Chun Liao,
  • Meng-Chih Lee and
  • Ching-Pyng Kuo

Objective: Diabetic foot ulcers are an invasive complication of diabetes and are increasing. This study investigates the relationship between health beliefs and foot self-care behaviors, among people with type II diabetes. Methods: A cross-sectional...

  • Article
  • Open Access
6 Citations
4,339 Views
14 Pages

Evaluation of Vaccine Strains Developed for Efficient, Broad-Range Protection against Foot-and-Mouth Disease Type O

  • Seong Yun Hwang,
  • Sung Ho Shin,
  • Hyun Mi Kim,
  • SeHee Shin,
  • Min Ja Lee,
  • Su-Mi Kim,
  • Jong-Soo Lee and
  • Jong-Hyeon Park

27 January 2023

Foot-and-mouth disease (FMD) type O includes 11 genetic topotypes. The Southeast Asia (SEA), Middle East–South Asia (ME-SA), and Cathay topotypes belong to FMD type O and occur frequently in Asia. Therefore, it is necessary to develop a potent...

  • Article
  • Open Access
5 Citations
4,242 Views
13 Pages

2 July 2021

The objective of this study was to quantify the increase in efficacy during the first four cycles of treatment with botulinum toxin type/A (BoNT/A) in 24 free-walking BoNT/A naïve adult patients with post-stroke hemispasticity and spastic foot drop....

  • Article
  • Open Access
2 Citations
3,523 Views
10 Pages

The Catalan diabetic foot health program was established in 2009 in order to prevent complications caused by type 2 diabetes. This study aims to describe its application from 2009 to 2018. The objective was to describe diabetic foot care provision in...

  • Article
  • Open Access
5 Citations
4,649 Views
16 Pages

Response Time to a Vibrotactile Stimulus Presented on the Foot at Rest and During Walking on Different Surfaces

  • Landry Delphin Chapwouo Tchakouté,
  • Louis Tremblay and
  • Bob-Antoine J. Menelas

29 June 2018

This study investigates the simple reaction time (SRT) and response time (RT) to a vibrotactile stimulus presented on two body locations at the lower extremity of the foot on different types of surface during walking. We determined RTs while walking...

  • Article
  • Open Access
3 Citations
2,428 Views
10 Pages

13 September 2022

Nurses are required to make quantitative, evidence-based observations when implementing diabetic foot care. This study aimed to clarify the characteristics of lower-limb ischemia in patients with type 2 diabetes using subjective and objective symptom...

  • Article
  • Open Access
1 Citations
2,609 Views
9 Pages

Diagnostic Nerve Block to Guide Botulinum Neurotoxin Type A Injection for Clonus in Spastic Equinovarus Foot: A Retrospective Study

  • Mirko Filippetti,
  • Stefano Tamburin,
  • Ilaria Di Maria,
  • Cecilia Angeli,
  • Rita Di Censo,
  • Elisa Mantovani,
  • Nicola Smania and
  • Alessandro Picelli

21 November 2024

Clonus is characterized by involuntary, rhythmic, oscillatory muscle contractions, typically triggered by rapid muscle stretching and is frequently associated with spastic equinovarus foot (SEVF), where it may increase risk of falls and cause discomf...

  • Article
  • Open Access
17 Citations
5,649 Views
20 Pages

14 August 2021

The lower limb joints might be affected by different shoe types and gait speeds. Monitoring joint angles might require skill and proper technique to obtain accurate data for analysis. We aimed to estimate the knee joint angle using a textile capaciti...

  • Article
  • Open Access
7 Citations
3,640 Views
12 Pages

Phage Display Screening of Bovine Antibodies to Foot-and-Mouth Disease Virus and Their Application in a Competitive ELISA for Serodiagnosis

  • Sukyo Jeong,
  • Hyun Joo Ahn,
  • Kyung Jin Min,
  • Jae Won Byun,
  • Hyun Mi Pyo,
  • Mi Young Park,
  • Bok Kyung Ku,
  • Jinju Nah,
  • Soyoon Ryoo and
  • Sang Jick Kim
  • + 1 author

For serodiagnosis of foot-and-mouth disease virus (FMDV), monoclonal antibody (MAb)-based competitive ELISA (cELISA) is commonly used since it allows simple and reproducible detection of antibody response to FMDV. However, the use of mouse-origin MAb...

  • Article
  • Open Access
2 Citations
2,963 Views
17 Pages

The Influence of Dapagliflozin on Foot Microcirculation in Patients with Type 2 Diabetes with and without Peripheral Arterial Disease—A Pilot Study

  • Božena Bradarić,
  • Tomislav Bulum,
  • Neva Brkljačić,
  • Željko Mihaljević,
  • Miroslav Benić and
  • Božo Bradarić Lisić

26 August 2024

The results of large cardiovascular studies indicate that SGLT-2 inhibitors may increase the risk of leg amputations. This study aims to investigate whether dapagliflozin therapy affects peripheral vascular oxygenation, i.e., microcirculation in the...

  • Article
  • Open Access
9 Citations
3,016 Views
14 Pages

Using Self-Assembling ADDomer Platform to Display B and T Epitopes of Type O Foot-and-Mouth Disease Virus

  • Chaowei Luo,
  • Quanhui Yan,
  • Juncong Huang,
  • Jiameng Liu,
  • Yuwan Li,
  • Keke Wu,
  • Bingke Li,
  • Mingqiu Zhao,
  • Shuangqi Fan and
  • Jinding Chen
  • + 1 author

18 August 2022

Foot-and-mouth disease virus (FMDV) is a highly contagious and devastating virus that infects cloven-hoofed livestock and various wildlife species. Vaccination is the best measure to prevent FMD. ADDomer, as a kind of non-infectious adenovirus-inspir...

  • Article
  • Open Access
13 Citations
2,727 Views
15 Pages

Lipid Profile Paradox: Investigating Improved Lipid Levels in Diabetic Mellitus Patients with Foot Ulcer Infections—A Prospective Descriptive Study

  • Andrei Ardelean,
  • Andreea-Adriana Neamtu,
  • Diana-Federica Balta,
  • Carmen Neamtu,
  • Dan Goldis,
  • Mihai Rosu,
  • Alexandru Nesiu,
  • Silviu Moldovan,
  • Cristi Tarta and
  • Bogdan Dan Totolici

25 November 2023

Type 2 diabetes mellitus (DM) is a chronic metabolic disorder posing multifaceted challenges to global public health. Among its numerous complications, infected diabetic foot ulcers (IDFUs) represent a particularly debilitating consequence. Beyond ca...

  • Article
  • Open Access
1 Citations
3,807 Views
10 Pages

Production of Foot-and-Mouth Disease Type O and A Vaccine Antigens on a Pilot Scale and Determination of Optimal Amount of Antigen for Monovalent Vaccines

  • Jae Young Kim,
  • Ji-Hye Lee,
  • Jong Min Yang,
  • Seo-Yong Lee,
  • Sun Young Park,
  • Jong Sook Jin,
  • Dohyun Kim,
  • Jung-Won Park,
  • Jong-Hyeon Park and
  • Young-Joon Ko
  • + 1 author

26 June 2023

Foot-and-mouth disease (FMD) is a highly infectious disease affecting cloven-hoofed animals and causes significant economic losses to the livestock industry. The Type O PanAsia-2 (O PA-2) vaccine strain is protective against a wide range of serotype...

  • Article
  • Open Access
6 Citations
3,492 Views
13 Pages

Modification of Tumor Necrosis Factor-α and C-C Motif Chemokine Ligand 18 Secretion by Monocytes Derived from Patients with Diabetic Foot Syndrome

  • Karine O. Galstyan,
  • Ludmila V. Nedosugova,
  • Narine S. Martirosian,
  • Nikita G. Nikiforov,
  • Natalia V. Elizova,
  • Kira I. Kolmychkova,
  • Igor A. Sobenin and
  • Alexander N. Orekhov

22 December 2019

Background: This study involves the investigation of spontaneous and induced secretion of the pro-inflammatory cytokine tumor necrosis factor-α (TNF-α) and the anti-inflammatory chemokine C-C motif chemokine ligand 18 (CCL18) by monocytes...

  • Article
  • Open Access
3 Citations
2,787 Views
10 Pages

Determination of Optimal Antigen Yield and Virus Inactivation Conditions for the Production of the Candidate Foot-and-Mouth Disease Recombinant Vaccine Strain Asia1 Shamir-R in a Bioreactor

  • Jae Young Kim,
  • Sun Young Park,
  • Gyeongmin Lee,
  • Sang Hyun Park,
  • Jong-Sook Jin,
  • Dohyun Kim,
  • Jong-Hyeon Park,
  • Seong-Yun Jeong and
  • Young-Joon Ko

16 March 2024

Since the foot-and-mouth disease (FMD) outbreak in South Korea in 2010–2011, vaccination policies utilizing inactivated FMD vaccines composed of types O and A have been implemented nationwide. However, because type Asia1 occurred in North Korea...

  • Article
  • Open Access
7 Citations
3,429 Views
13 Pages

22 November 2022

In South Korea, testing disinfectants against foot-and-mouth disease virus (FMDV) that are contagious in livestock or that require special attention with respect to public hygiene can be manipulated only in high-level containment laboratories, which...

  • Article
  • Open Access
10 Citations
2,846 Views
22 Pages

Single nucleotide polymorphisms (SNP) in the RAC1 (Rac family small GTPase 1) gene have recently been linked to type 2 diabetes (T2D) and hyperglycemia due to their contribution to impaired redox homeostasis. The present study was designed to determi...

  • Article
  • Open Access
844 Views
21 Pages

Inactivated Type ‘O’ Foot and Mouth Disease Virus Encapsulated in Chitosan Nanoparticles Induced Protective Immune Response in Guinea Pigs

  • Kalaivanan Ramya,
  • Subodh Kishore,
  • Palanisamy Sankar,
  • Ganesh Kondabatulla,
  • Bedaso Mamo Edao,
  • Ramasamy Saravanan and
  • Kumaraguruban Karthik

9 December 2025

Foot and mouth disease is a contagious viral disease infecting ungulates, with great economic impact on farmers’ income; it is primarily controlled using inactivated vaccines, which have certain limitations, such as short-lived immunity and a l...

  • Article
  • Open Access
9 Citations
6,892 Views
12 Pages

Split hand/foot malformation (SHFM) is a limb malformation with underdeveloped or absent central digital rays, clefts of hands and feet, and variable syndactyly of the remaining digits. There are six types of SHFM. Here, we report a boy with SHFM typ...

  • Article
  • Open Access
6 Citations
2,223 Views
13 Pages

PRP of T2DM Patient Immobilized on PCL Nanofibers Stimulate Endothelial Cells Proliferation

  • Anastasiya O. Solovieva,
  • Natalia A. Sitnikova,
  • Vadim V. Nimaev,
  • Elena A. Koroleva and
  • Anton M. Manakhov

Diabetic foot ulcers (DFU) are a common complication of Type 2 Diabetes Mellitus (T2DM). Development of bioactive wound healing covers is an important task in medicine. The use of autologous platelet-rich plasma (PRP) consisting of growth factors, cy...

  • Article
  • Open Access
12 Citations
3,751 Views
12 Pages

Caffeic Acid in Spent Coffee Grounds as a Dual Inhibitor for MMP-9 and DPP-4 Enzymes

  • Enade P. Istyastono,
  • Nunung Yuniarti,
  • Vivitri D. Prasasty,
  • Sudi Mungkasi,
  • Stephanus S. W. Waskitha,
  • Michael R. S. Yanuar and
  • Florentinus D. O. Riswanto

19 October 2023

Type 2 diabetes mellitus and diabetic foot ulcers remain serious worldwide health problems. Caffeic acid is one of the natural products that has been experimentally proven to have diverse pharmacological properties. This study aimed to assess the inh...

  • Article
  • Open Access
654 Views
12 Pages

Development of a Chimeric Vaccine Providing Protection Against the Type A ASIA/Sea-97 FMDVs in East Asia

  • Sungho Shin,
  • Seong Yun Hwang,
  • Mi-Kyeong Ko,
  • Min Ja Lee,
  • Su-Mi Kim,
  • Jaejo Kim and
  • Jong-Hyeon Park

29 October 2025

Background/Objectives: Foot-and-mouth disease (FMD) remains a significant threat to livestock, particularly in the pool 1 region (East Asia), where serotype A is prevalent. Vaccination is the most effective control measure, and the selection of the a...

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