You are currently on the new version of our website. Access the old version .

140 Results Found

  • Article
  • Open Access
6 Citations
2,749 Views
12 Pages

25 November 2023

Echinacea purpurea is popularly used as a food supplement or nutritional supplement for its immune regulatory function against various threats. As one of its promising components, Echinacea purpurea (L.) Moench polysaccharide (EPP) has a wide range o...

  • Communication
  • Open Access
36 Citations
7,363 Views
12 Pages

29 September 2021

The human body is home to a complex community of dynamic equilibrium microbiota, including bacteria, fungi, parasites, and viruses. It is known that the gut microbiome plays a crucial role in regulating innate and adaptive immune responses, intestina...

  • Article
  • Open Access
25 Citations
3,404 Views
19 Pages

Schistosomiasis is an immunopathogenic disease in which a T helper (Th) cell type 2-like response plays vital roles. Hepatic fibrosis is its main pathologic manifestations, which is the leading cause of hepatic cirrhosis. Co-infections of Schistosoma...

  • Article
  • Open Access
11 Citations
4,312 Views
13 Pages

27 April 2018

As a kind of antimicrobial peptides (AMP) in crustacean, anti-lipopolysaccharide factors (ALFs) have broad spectrum antimicrobial activities. In the present study, we identified four ALF genes, EcALF2-5, from the ridgetail prawn Exopalaemon carinicau...

  • Article
  • Open Access
54 Citations
6,138 Views
11 Pages

Effects of Tea Saponin Supplementation on Nutrient Digestibility, Methanogenesis, and Ruminal Microbial Flora in Dorper Crossbred Ewe

  • Yunlong Liu,
  • Tao Ma,
  • Dandan Chen,
  • Naifeng Zhang,
  • Bingwen Si,
  • Kaidong Deng,
  • Yan Tu and
  • Qiyu Diao

21 January 2019

Two experiments were conducted using Dorper × thin-tailed Han crossbred ewes. In experiment 1, eighteen ewes were randomly assigned to two dietary treatments (a basal diet, or the same basal diet supplemented with 2.0 g tea saponin (TS)/head/da...

  • Article
  • Open Access
4 Citations
1,687 Views
13 Pages

25 December 2024

Previous studies have shown that supplementation with specific probiotics can be used to alleviate allergy symptoms. The purpose of this study was to evaluate the anti-allergic effects of Lactobacillus kefiranofaciens ZW3 (ZW3) in ovalbumin (OVA)-ind...

  • Review
  • Open Access
12 Citations
6,367 Views
35 Pages

Neuroinflammation and Natural Antidepressants: Balancing Fire with Flora

  • Ana Clara Figueiredo Godoy,
  • Fernanda Fortes Frota,
  • Larissa Parreira Araújo,
  • Vitor E. Valenti,
  • Eliana de Souza Bastos Mazuqueli Pereira,
  • Claudia Rucco P. Detregiachi,
  • Cristiano M. Galhardi,
  • Flávia Cristina Caracio,
  • Rafael S. A. Haber and
  • Lucas Fornari Laurindo
  • + 2 authors

Background/Objectives: Major depressive disorder (MDD) is a major global health concern that is intimately linked to neuroinflammation, oxidative stress, mitochondrial dysfunction, and complicated metabolic abnormalities. Traditional antidepressants...

  • Article
  • Open Access
3 Citations
2,928 Views
12 Pages

Effects of Compound Probiotics on Cecal Microbiota and Metabolome of Swine

  • Jie Li,
  • Hongyue Li,
  • Yi Zhou,
  • Hongwei Xiang,
  • Muze Lv,
  • Bo Ruan,
  • Zongyi Bo,
  • Haixiao Shen,
  • Fazhi Xu and
  • Yafeng Huang
  • + 2 authors

10 March 2023

Complex probiotics are made from various single probiotics mixed in scientific formula. The long-term intake of different probiotics is beneficial to maintain the intestinal microecological balance, inhibiting harmful pathogenic flora and facilitatin...

  • Review
  • Open Access
2,885 Views
19 Pages

Rheumatoid arthritis (RA) is a chronic autoimmune disease that has a serious impact on both human health and animal production. The gut microbiota is a large and complex symbiotic ecosystem in animals, and the imbalance of gut microbiota is closely r...

  • Review
  • Open Access
61 Citations
12,580 Views
19 Pages

Armed to the Teeth—The Oral Mucosa Immunity System and Microbiota

  • Maja Ptasiewicz,
  • Ewelina Grywalska,
  • Paulina Mertowska,
  • Izabela Korona-Głowniak,
  • Agata Poniewierska-Baran,
  • Paulina Niedźwiedzka-Rystwej and
  • Renata Chałas

The oral cavity is inhabited by a wide spectrum of microbial species, and their colonization is mostly based on commensalism. These microbes are part of the normal oral flora, but there are also opportunistic species that can cause oral and systemic...

  • Article
  • Open Access
10 Citations
4,642 Views
22 Pages

13 February 2024

Eggs, with their high nutritional value, are great carriers for enriching nutrients. In this study, selenium- and/or zinc-enriched eggs (SZE) were obtained and their effects on ameliorating oxidative stress injury, alleviating cognitive impairment, a...

  • Article
  • Open Access
3 Citations
3,294 Views
23 Pages

Federated Learning for privacy-Friendly Health Apps: A Case Study on Ovulation Tracking

  • Nikolaos Pavlidis,
  • Andreas Sendros,
  • Theodoros Tsiolakis,
  • Periklis Kostamis,
  • Christos Karasoulas,
  • Eleni Briola,
  • Christos Chrysanthos Nikolaidis,
  • Vasilis Perifanis,
  • George Drosatos and
  • Eleftheria Katsiri
  • + 3 authors

In an era of increasing reliance on digital health solutions, safeguarding user privacy has emerged as a paramount concern. Health applications often need to balance advanced AI functionalities with sufficient privacy measures to ensure user engageme...

  • Review
  • Open Access
49 Citations
15,575 Views
20 Pages

Effects of Fermented Food Consumption on Non-Communicable Diseases

  • Priya Patel,
  • Krishna Butani,
  • Akash Kumar,
  • Sudarshan Singh and
  • Bhupendra G. Prajapati

4 February 2023

The gastrointestinal flora consists of several microbial strains in variable combinations in both healthy and sick humans. To prevent the risk of the onset of disease and perform normal metabolic and physiological functions with improved immunity, a...

  • Review
  • Open Access
47 Citations
17,764 Views
19 Pages

Research Progress for Probiotics Regulating Intestinal Flora to Improve Functional Dyspepsia: A Review

  • Xinyu Shen,
  • Aijun Xie,
  • Zijing Li,
  • Chengxi Jiang,
  • Jiaqi Wu,
  • Mohan Li and
  • Xiqing Yue

2 January 2024

Functional dyspepsia (FD) is a common functional gastrointestinal disorder. The pathophysiology remains poorly understood; however, alterations in the small intestinal microbiome have been observed. Current treatments for FD with drugs are limited, a...

  • Article
  • Open Access
28 Citations
4,393 Views
17 Pages

Dietary Recombinant Phycoerythrin Modulates the Gut Microbiota of H22 Tumor-Bearing Mice

  • Hongtao Qi,
  • Ying Liu,
  • Xin Qi,
  • Hui Liang,
  • Huaxin Chen,
  • Peng Jiang and
  • Dongfeng Wang

26 November 2019

Normal intestinal flora is widely involved in many functions of the host: nutritional metabolism; maintenance of intestinal microecological balance; regulation of intestinal endocrine function and nerve signal transduction; promotion of intestinal im...

  • Article
  • Open Access
973 Views
21 Pages

26 October 2025

The Mystras UNESCO World Heritage Site (MUWHS) is a medieval historical area located on a small hill facing Sparta in the Mediterranean hotspot of the Peloponnese and receives a high number of visitors annually. The main aim of this study is the inve...

  • Article
  • Open Access
12 Citations
4,734 Views
14 Pages

Effects of Spermidine on Mouse Gut Morphology, Metabolites, and Microbial Diversity

  • Dong-Mei Jiang,
  • Ze-Long Wang,
  • Jia-Di Yang,
  • Xin Wang,
  • Chun-Yang Niu,
  • Cheng-Weng Ji,
  • Wei-Kang Ling,
  • Xiao-Guang An,
  • Yong-Ni Guo and
  • Qian Sun
  • + 4 authors

1 February 2023

Spermidine is a class of biologically active organic small molecules that play an important role in maintaining intestinal homeostasis. The specific objective of this study was to explore the effects of spermidine on intestinal morphology, metabolite...

  • Article
  • Open Access
2 Citations
2,239 Views
13 Pages

Effects of Stocking Density on Fatty Acid Metabolism by Skeletal Muscle in Mice

  • Qiuyan Chen,
  • Xiaohui Li,
  • Jiarun Cui,
  • Caiyun Xu,
  • Hongfei Wei,
  • Qian Zhao,
  • Hongli Yao,
  • Hailong You,
  • Dawei Zhang and
  • Huimei Yu

22 September 2022

Specific pathogen-free (SPF) grade laboratory animals are kept in specific cages for life. The limited space could affect the characterization of colonization and dynamic changes related to gut microorganisms, and affect adipokines, even further affe...

  • Article
  • Open Access
7 Citations
3,992 Views
20 Pages

Deep Learning Application for Biodiversity Conservation and Educational Tourism in Natural Reserves

  • Marco Flórez,
  • Oscar Becerra,
  • Eduardo Carrillo,
  • Manny Villa,
  • Yuli Álvarez,
  • Javier Suárez and
  • Francisco Mendes

Natural reserves, such as the Santurbán Moor in Colombia, are ecologically important but face significant threats from activities like mining and agriculture. Preserving biodiversity in these ecosystems is essential for maintaining ecological...

  • Review
  • Open Access
28 Citations
8,124 Views
17 Pages

19 March 2023

Cognitive, mood and sleep disorders are common and intractable disorders of the central nervous system, causing great inconvenience to the lives of those affected. The gut–brain axis plays a vital role in studying neurological disorders such as neuro...

  • Article
  • Open Access
11 Citations
3,379 Views
17 Pages

Serum Untargeted Metabolism Reveals the Mechanism of L. plantarum ZDY2013 in Alleviating Kidney Injury Induced by High-Salt Diet

  • Cuixiang Wan,
  • Shufang Chen,
  • Kui Zhao,
  • Zhongyue Ren,
  • Lingling Peng,
  • Huiling Xia,
  • Hua Wei and
  • Bo Yu

1 November 2021

A high-salt diet (HSD) is one of the key risk factors for hypertension and kidney injury. In this study, a HSD C57BL/6J mice model was established with 4% NaCl, and then different concentrations of Lactobacillus plantarum ZDY2013 were intragastricall...

  • Article
  • Open Access
5 Citations
2,075 Views
20 Pages

Characteristics of Citrate-Esterified Starch and Enzymatically Debranched Starch and Their Effects on Diabetic Mice

  • Nannan Wang,
  • Changhe Ding,
  • Yingying Xie,
  • Jun Meng,
  • Xing Fan,
  • Duoduo Fan,
  • Haowei Wan and
  • Zhengqiang Jiang

10 May 2024

Chickpea has significant benefits as an adjuvant treatment for type 2 diabetes mellitus (T2DM). The properties of chickpea resistant starches (RSs) and their abilities to reduce T2DM symptoms and control intestinal flora were investigated. The RS con...

  • Review
  • Open Access
44 Citations
9,053 Views
14 Pages

13 February 2022

Cattle have a genital microbiome that is established early in life, even before calving. Microbial influx into the reproductive system of cows, during calving or mating, is unavoidable and is likely to alter the commensal microflora composition. It i...

  • Communication
  • Open Access
3 Citations
7,749 Views
10 Pages

Exploration of the Native Plants from the Biodiversity of United Arab Emirates for Conservation and Reintroduction Efforts: Collection, Verification, Design, and Implementation of UAE Flora Database

  • Naamah Ahmed Salem Aldhabb Alyammahi,
  • Fouad Lamghari Ridouane,
  • Aseela Abdulla Almoalla,
  • Aishah Saeed Sulaiman Jemei Al Dhanhani,
  • Ahmed Gorashi and
  • Shaher Bano Mirza

The introduction of exotic plant species in the UAE poses substantial environmental challenges. Both poorly and well-adapted species can be detrimental to the local ecosystem by outcompeting native species and disrupting ecosystems. Native plants pla...

  • Article
  • Open Access
109 Citations
7,972 Views
20 Pages

7 December 2018

Dendrobium is a traditional Chinese herb with anti-diabetic effects and has diverse bibenzyls as well as phenanthrenes. Little is known about Dendrobium polyphenols anti-diabetic activities, so, a rich-polyphenols extract of D. loddigesii (DJP) was u...

  • Article
  • Open Access
6 Citations
3,343 Views
21 Pages

Antimicrobial Photodynamic Inactivation: An Alternative for Group B Streptococcus Vaginal Colonization in a Murine Experimental Model

  • Michał K. Pierański,
  • Jan G. Kosiński,
  • Klaudia Szymczak,
  • Piotr Sadowski and
  • Mariusz Grinholc

Background: Streptococcus agalactiae, referred to as Group B Streptococcus (GBS), is a prominent bacterium causing life-threatening neonatal infections. Although antibiotics are efficient against GBS, growing antibiotic resistance forces the search f...

  • Review
  • Open Access
551 Citations
53,404 Views
19 Pages

Candida albicans—The Virulence Factors and Clinical Manifestations of Infection

  • Jasminka Talapko,
  • Martina Juzbašić,
  • Tatjana Matijević,
  • Emina Pustijanac,
  • Sanja Bekić,
  • Ivan Kotris and
  • Ivana Škrlec

22 January 2021

Candida albicans is a common commensal fungus that colonizes the oropharyngeal cavity, gastrointestinal and vaginal tract, and healthy individuals’ skin. In 50% of the population, C. albicans is part of the normal flora of the microbiota. The v...

  • Review
  • Open Access
15 Citations
6,900 Views
15 Pages

The Contribution of the Skin Microbiome to Psoriasis Pathogenesis and Its Implications for Therapeutic Strategies

  • Diana Sabina Radaschin,
  • Alin Tatu,
  • Alina Viorica Iancu,
  • Cristina Beiu and
  • Liliana Gabriela Popa

3 October 2024

Psoriasis is a common chronic inflammatory skin disease, associated with significant morbidity and a considerable negative impact on the patients’ quality of life. The complex pathogenesis of psoriasis is still incompletely understood. Genetic...

  • Review
  • Open Access
70 Citations
10,019 Views
18 Pages

12 February 2018

Soybean agglutinin (SBA) is a non-fiber carbohydrate-related protein and the main anti-nutritional factor that exists in soybean or soybean products. SBA possesses a specific binding affinity for N-glyphthalide-d-galactosamine or galactose and has a...

  • Review
  • Open Access
1 Citations
1 Views
15 Pages

Probiotics: Defenders of Gastrointestinal Habitats

  • Desh D. Singh,
  • Sarika Amdeka and
  • Vinod Singh

Intestinal microbiota play an important role in maintaining normal gastrointestinal (GI) function and ensuring that changes in the composition of the intestinal microbiota can promote GI function. The digestive tract is full of bacteria and many of t...

  • Article
  • Open Access
28 Citations
3,834 Views
15 Pages

3 August 2023

Bacteriocins production is one of important beneficial characteristics of probiotics, which has antibacterial property against intestinal pathogens and is helpful for regulating intestinal flora. To investigate the impact of bacteriocin-producing pro...

  • Article
  • Open Access
6 Citations
2,188 Views
15 Pages

Probiotics play an important role in animal production, providing health benefits to the host by improving intestinal microbial balance. In this study, we added three different probiotics, Saccharomyces cerevisiae (SC), Bacillus licheniformis (BL), a...

  • Article
  • Open Access
40 Citations
5,488 Views
19 Pages

Effects of Shrimp Peptide Hydrolysate on Intestinal Microbiota Restoration and Immune Modulation in Cyclophosphamide-Treated Mice

  • Asif Iqbal Khan,
  • Ata Ur Rehman,
  • Nabeel Ahmed Farooqui,
  • Nimra Zafar Siddiqui,
  • Qamar Ayub,
  • Muhammad Noman Ramzan,
  • Liang Wang and
  • Yi Xin

The gut microbiota is important in regulating host metabolism, maintaining physiology, and protecting immune homeostasis. Gut microbiota dysbiosis affects the development of the gut microenvironment, as well as the onset of various external systemic...

  • Article
  • Open Access
18 Citations
3,948 Views
22 Pages

Effects of Clostridium butyricum on Intestinal Microflora and Metabolism of Eriocheir sinensis

  • Xiaoning Gao,
  • Xueting Liu,
  • Yali Wang,
  • Tianwei Wang,
  • Di Fang and
  • Kun Hu

7 September 2023

Clostridium butyricum, a new probiotic in recent years, can produce butyric acid and short-chain fatty acids. It has the characteristics of strong acid and alkali resistance, high temperature resistance, and strong resistance to most antibiotics, and...

  • Review
  • Open Access
11 Citations
5,874 Views
20 Pages

8 January 2025

Probiotics are an essential dietary supplement for intestinal flora balance, inhibition of pathogenic bacteria and immune regulation. However, probiotic inactivation during gastrointestinal transportation remains a big challenge for oral administrati...

  • Article
  • Open Access
51 Citations
5,104 Views
13 Pages

15 March 2020

Deoxynivalenol (DON) is one of the most prevalent food- and feed-associated mycotoxins. It frequently contaminates agricultural commodities and poses serious threats to human and animal health and leads to tremendous economic losses globally. Much at...

  • Article
  • Open Access
10 Citations
2,187 Views
13 Pages

Development of an Algorithm for Calculating the Moisture Content and Time of Forest Fire Maturation of Forest Combustible Materials for Determining Forest Fire Hazards

  • Anatoliy A. Aleksandrov,
  • Boris S. Ksenofontov,
  • Alexey S. Kozodaev,
  • Roman A. Taranov,
  • Victoriya D. Vyazova and
  • Mikhail V. Ivanov

Nowadays, forests play an important role in stabilizing the ecological balance, being one of the most important components of the biosphere. Due to the vital activity of forests, the gas composition of the atmosphere is normalized. Mass forest fires...

  • Review
  • Open Access
838 Citations
34,280 Views
15 Pages

Antioxidant Properties of Probiotic Bacteria

  • Yang Wang,
  • Yanping Wu,
  • Yuanyuan Wang,
  • Han Xu,
  • Xiaoqiang Mei,
  • Dongyou Yu,
  • Yibing Wang and
  • Weifen Li

19 May 2017

Oxidative stress defines a condition in which the prooxidant–antioxidant balance in the cell is disturbed, resulting in DNA hydroxylation, protein denaturation, lipid peroxidation, and apoptosis, ultimately compromising cells’ viability. Probiotics h...

  • Article
  • Open Access
3 Citations
6,666 Views
22 Pages

27 September 2024

Currently, the lack of adequate spaces for raising awareness among the population, coupled with disorderly urban growth, has led to an increase in water pollution from solid waste and the disruption of natural habitats in Villa Marshes. Therefore, th...

  • Article
  • Open Access
1,022 Views
17 Pages

Application of Lactobacillus helveticus KLDS 1.1105 Postbiotics for Resisting Pathogenic Bacteria Infection in the Intestine

  • Peng Du,
  • Jiaying Liu,
  • Chengwen Hu,
  • Jianing Zhang,
  • Miao Li,
  • Yu Xin,
  • Libo Liu,
  • Aili Li and
  • Chun Li

29 July 2025

Postbiotics, defined as metabolites produced by probiotics, encompass both bacterial cells and their metabolic byproducts, and offer significant health benefits to the host. However, there are relatively few reports on their effects on intestinal mic...

  • Article
  • Open Access
87 Citations
11,612 Views
9 Pages

18 May 2015

Atopic dermatitis is a form of dermatitis commonly seen in children and adults. Its pathophysiology is complex and is centered on the barrier function of the epidermis. An important aspect of the skin’s barrier is pH, which in turn affects a number...

  • Article
  • Open Access
3 Citations
4,836 Views
22 Pages

Influence of Housing Systems on Physical, Emotional, and Cognitive Functions with Aging in DBA/2CrSlc Mice

  • Chikako Shimizu,
  • Yoshihisa Wakita,
  • Youichi Tsuchiya and
  • Toshitaka Nabeshima

24 April 2020

Environmental conditions, including enrichment and stress, affect animal behaviors, but limited information is available regarding the differences in animal functions between the chamber (ventilated system) vs. IVC (individually ventilated cages) hou...

  • Article
  • Open Access
16 Citations
6,990 Views
17 Pages

Faecalibacterium prausnitzii Supplementation Prevents Intestinal Barrier Injury and Gut Microflora Dysbiosis Induced by Sleep Deprivation

  • Xintong Wang,
  • Yixuan Li,
  • Xifan Wang,
  • Ran Wang,
  • Yanling Hao,
  • Fazheng Ren,
  • Pengjie Wang and
  • Bing Fang

9 April 2024

Sleep deprivation (SD) leads to impaired intestinal barrier function and intestinal flora disorder, especially a reduction in the abundance of the next generation of probiotic Faecalibacterium prausnitzii (F. prausnitzii). However, it remains largely...

  • Article
  • Open Access
585 Views
26 Pages

25 December 2025

This article analyzes prohibitions against the destruction of flora in the calendrical regulations of the late Western Han period and in the millenarian cosmological discourses in the Taiping jing 太平經 (Canon of Great Peace). The...

  • Review
  • Open Access
44 Citations
5,710 Views
17 Pages

Microbiota in Pancreatic Diseases: A Review of the Literature

  • Tommaso Schepis,
  • Sara S. De Lucia,
  • Enrico C. Nista,
  • Vittoria Manilla,
  • Giulia Pignataro,
  • Veronica Ojetti,
  • Andrea Piccioni,
  • Antonio Gasbarrini,
  • Francesco Franceschi and
  • Marcello Candelli

17 December 2021

The gut microbiota is a critical element in the balance between human health and disease. Its impairment, defined as dysbiosis, is associated with gastroenterological and systemic diseases. Pancreatic secretions are involved in the composition and ch...

  • Article
  • Open Access
242 Citations
24,930 Views
14 Pages

Human Milk Oligosaccharides: Health Benefits, Potential Applications in Infant Formulas, and Pharmacology

  • Michał Wiciński,
  • Ewelina Sawicka,
  • Jakub Gębalski,
  • Karol Kubiak and
  • Bartosz Malinowski

20 January 2020

The first months of life are a special time for the health development and protection of infants. Breastfeeding is the natural and best way of feeding an infant, and positively influences their development and health. Breast milk provides the ideal b...

  • Review
  • Open Access
16 Citations
4,704 Views
18 Pages

Biocontrol of Candida albicans by Antagonistic Microorganisms and Bioactive Compounds

  • Honghua Li,
  • Jinpeng Yang,
  • Xinwan Zhang,
  • Xiuli Xu,
  • Fuhang Song and
  • Hehe Li

12 September 2022

Candida albicans is an endogenous opportunistic pathogenic fungus that is harmless when the host system remains stable. However, C. albicans could seriously threaten human life and health when the body’s immune function declines or the normal f...

  • Review
  • Open Access
6 Citations
5,109 Views
13 Pages

Periodontitis is an irreversible inflammatory response that occurs in periodontal tissues. Given the size and diversity of natural flora in the oral mucosa, host immunity must strike a balance between pathogen identification and a complicated system...

  • Article
  • Open Access
10 Citations
3,269 Views
20 Pages

Temperature Modeling, a Key to Assessing Impact on Rivers Due to Urbanization and Climate Change

  • Edward McBean,
  • Munir Bhatti,
  • Amanjot Singh,
  • Logan Mattern,
  • Lorna Murison and
  • Patrick Delaney

22 June 2022

With widespread ongoing urbanization and as climate change continues, the importance of protecting the water quality of streams and lakes is intensifying. However, while many water quality constituents in lakes and rivers are of overall interest, wat...

  • Review
  • Open Access
34 Citations
8,516 Views
10 Pages

The Microbiota-Gut-Brain Axis as a Key to Neuropsychiatric Disorders: A Mini Review

  • Katarzyna Stopińska,
  • Maria Radziwoń-Zaleska and
  • Izabela Domitrz

10 October 2021

The central nervous system (CNS) is closely related to the gastrointestinal tract, mainly through regulating its function and homeostasis. Simultaneously, the gut flora affects the CNS and plays an essential role in the pathogenesis of neurologic and...

of 3