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3,586 Results Found

  • Article
  • Open Access
17 Citations
7,119 Views
13 Pages

Physician Experience with Direct-To-Consumer Genetic Testing in Kaiser Permanente

  • M. Cabell Jonas,
  • Pim Suwannarat,
  • Andrea Burnett-Hartman,
  • Nikki Carroll,
  • Michelle Turner,
  • Kristen Janes,
  • Christine Truong,
  • Erica Blum-Barnett,
  • Nazneen Aziz and
  • Elizabeth A. McGlynn

1 November 2019

Health systems and physicians nationwide aspire to consistently and reliably apply genetic and genomic information to guide disease prevention, management, and treatment. However, clinical information, including genetics/genomics data from within and...

  • Review
  • Open Access
12 Citations
3,975 Views
13 Pages

Strategies to Improve the Clinical Outcomes for Direct-to-Consumer Pharmacogenomic Tests

  • Alireza Tafazoli,
  • Rama Krishna Guggilla,
  • Zahra Kamel-Koleti and
  • Wojciech Miltyk

3 March 2021

Direct-to-consumer genetic tests (DTC-GT) have become a bridge between marketing and traditional healthcare services. After earning FDA endorsement for such facilities, several fast-developing companies started to compete in the related area. Pharmac...

  • Article
  • Open Access
3 Citations
3,544 Views
16 Pages

30 November 2022

Direct-to-consumer genetic services allow companion animal guardians to purchase a DNA test and receive detailed results about their pet’s ancestry, health, and traits results. In collaboration with Wisdom Panel, we present novel findings about...

  • Commentary
  • Open Access
33 Citations
13,979 Views
7 Pages

Direct-to-consumer genetic testing (DTC-GT) companies are engaging health consumers in unprecedented ways and leveraging the genetic information they collect to further engage health companies. This has produced controversy about DTC-GT consumer expe...

  • Article
  • Open Access
10 Citations
9,414 Views
13 Pages

14 October 2013

Little is known about how consumers of direct-to-consumer personal genetic services share personal genetic risk information. In an age of ubiquitous online networking and rapid development of social networking tools, understanding how consumers share...

  • Article
  • Open Access
1 Citations
3,541 Views
15 Pages

3 July 2023

This article examines representations of multiple sclerosis in direct-to-consumer pharmaceutical advertisements televised during 2021 in the United States. Drawing on and developing Cultural Disability Studies theory, it highlights how advertising pr...

  • Review
  • Open Access
18 Citations
3,669 Views
15 Pages

23 March 2023

Direct-to-consumer (DTC) genetic tests have generated considerable scholarly attention and public intrigue. Although the current consumer genetic testing regime relies on the reporting of individual variants of interest to consumers, there has recent...

  • Article
  • Open Access
21 Citations
11,946 Views
29 Pages

9 July 2014

The increasing prominence of new Internet and social media technologies and their growing importance as a source of health information are pushing the pharmaceutical industry towards digital channels. This paper explores the potential impacts of the...

  • Article
  • Open Access
8 Citations
6,289 Views
17 Pages

With more than 25 million tests sold by early 2019, direct-to-consumer genetic ancestry tests expose the public to critical issues of genetics, ancestry, and identity. This study examines how individuals understand the results of a genetic ancestry t...

  • Article
  • Open Access
3 Citations
3,071 Views
15 Pages

25 January 2024

The role of genetic counselors is evolving in response to health-related direct-to-consumer genetic tests (DTC-GT). While there is consensus in the literature that pre- and post-DTC-GT genetic counseling would benefit consumers, genetic counselors ha...

  • Article
  • Open Access
4 Citations
6,156 Views
13 Pages

4 October 2018

Genetic testing has expanded out of the research laboratory into medical practice and the direct-to-consumer market. Rapid analysis of the resulting genotype data now has a significant impact. We present a method for summarizing personal genotypes as...

  • Article
  • Open Access
4 Citations
3,468 Views
18 Pages

Information Provision Regarding Health-Related Direct-to-Consumer Genetic Testing for Dutch Consumers: An in-Depth Content Analysis of Sellers’ Websites

  • Danny Bruins,
  • Suzanne M. Onstwedder,
  • Martina C. Cornel,
  • Margreet G. E. M. Ausems,
  • Marc H. W. van Mil and
  • Tessel Rigter

20 April 2024

Background: Previous studies have suggested that information offered by sellers of health-related direct-to-consumer genetic tests (DTC-GTs) is often incomplete, unbalanced, or too difficult to understand. The extent to which this is the case for sel...

  • Article
  • Open Access
4 Citations
2,652 Views
9 Pages

17 July 2023

Background—Direct-to-consumer (DTC) sequential aligners promote “teeth straightening” at a low cost and with added patient convenience. DTC sequential aligners have risen in popularity among the general public and sparked debate amo...

  • Article
  • Open Access
13 Citations
4,654 Views
23 Pages

Spatial Considerations for Implementing Two Direct-to-Consumer Food Models in Two States

  • Marilyn Sitaker,
  • Jared T. McGuirt,
  • Weiwei Wang,
  • Jane Kolodinsky and
  • Rebecca A. Seguin

8 April 2019

To open new markets, some farmers have adapted direct-to-consumer (DTC) models, such as Community Supported Agriculture (CSA), to reach new settings or audiences. We compared sociodemographic and geospatial contexts to farmers’ experience with...

  • Article
  • Open Access
3 Citations
2,819 Views
11 Pages

22 December 2022

Introduction: Sharing genetic test results with different stakeholders such as family members, healthcare providers and genetic counselors (HCP/GCs), spouses/partners, and friends is a health behavior of clinical importance in genomic medicine. Metho...

  • Article
  • Open Access
1 Citations
2,891 Views
8 Pages

2 September 2021

The overall goal of this study was to employ direct-to-consumer advertisements (DTCAs) as a teaching tool in a Doctor of Pharmacy (PharmD) curriculum. The objectives of this pilot study were to investigate the following questions: 1. Do DTCAs generat...

  • Review
  • Open Access
38 Citations
13,226 Views
13 Pages

Direct-to-Consumer Nutrigenetics Testing: An Overview

  • Matteo Floris,
  • Antonella Cano,
  • Laura Porru,
  • Roberta Addis,
  • Antonio Cambedda,
  • Maria Laura Idda,
  • Maristella Steri,
  • Carlo Ventura and
  • Margherita Maioli

21 February 2020

At present, specialized companies offering genetic testing services without the involvement of clinicians are growing; this development is a direct consequence of the significant decrease in genotyping and sequencing costs. Online companies offer pre...

  • Article
  • Open Access
7 Citations
8,677 Views
9 Pages

30 October 2012

Direct to consumer (DTC) genomic services facilitate the personalized and participatory aspects of “P4” medicine, but raise questions regarding use of genomic data in providing predictive and preventive healthcare. We illustrate the issues involved b...

  • Commentary
  • Open Access
4 Citations
8,799 Views
9 Pages

18 March 2014

The yet-unrealized potential for more “personalized” Direct-to-Consumer (DTC) tests to fundamentally alter the practice and economics of healthcare is undeniable. However, there are also many challenges to be met, including the herculean task of ensu...

  • Communication
  • Open Access
1,173 Views
9 Pages

Musculoskeletal Magazine Advertising Focuses on White Individuals and Overlooks Minority Consumers

  • Wei Shao Tung,
  • Kelsey A. Rankin,
  • Robert John Oris,
  • Adithi Wijesekera and
  • Daniel H. Wiznia

Introduction: Demographic disparities in musculoskeletal (MSK) health exist in the US. Racial representation in advertising has been shown to influence consumer behavior and buying patterns. Direct-to-consumer advertising that does not target a racia...

  • Article
  • Open Access
3,276 Views
25 Pages

10 September 2025

The beverage industry is undergoing a dynamic transition in terms of how and where consumers buy products. In an era of rapid digitalization and shifting consumer behaviors, this study investigates how Germany’s wine producers reach consumers a...

  • Article
  • Open Access
14 Citations
10,980 Views
19 Pages

12 September 2012

Sports-related genetic testing is a sector of the diverse direct-to-consumer (DTC) industry that has not yet been examined thoroughly by academic scholars. A systematic search was used to identify companies in this sector and content analysis of onli...

  • Article
  • Open Access
1 Citations
3,775 Views
19 Pages

12 November 2024

The increasing availability of direct-to-consumer personalized nutrition products has raised questions about their scope of personalization and added value compared to general dietary guidelines. This study evaluated eleven personalized nutrition pro...

  • Article
  • Open Access
1,589 Views
13 Pages

User Experience, Satisfaction, and Complications of Direct-to-Consumer Orthodontics in Spain: A Cross-Sectional Study

  • Milagros Adobes Martin,
  • Adriana Pérez Márquez,
  • Simonetta Meuli,
  • Adrian Curtó Aguilera,
  • Mario Dioguardi,
  • Riccardo Aiuto and
  • Daniele Garcovich

30 March 2025

Background/Objectives: Direct-to-Consumer Orthodontics (DTCO) has gained popularity through social media, offering clear aligner treatments without in-person supervision. However, there is limited research on the related user experiences, satisfactio...

  • Article
  • Open Access
14 Citations
3,383 Views
11 Pages

The Screen Project: Guided Direct-To-Consumer Genetic Testing for Breast Cancer Susceptibility in Canada

  • Steven A. Narod,
  • Nicole Gojska,
  • Ping Sun,
  • Angelina Tryon,
  • Joanne Kotsopoulos,
  • Kelly Metcalfe and
  • Mohammad R. Akbari

15 April 2021

There is limited information of the outcomes of direct-to-consumer testing for BRCA1 and BRCA2 mutations. The Screen Project was initiated in 2017 to offer BRCA1 and BRCA2 genetic screening to all Canadians over the age of 18 who wish to know their m...

  • Review
  • Open Access
36 Citations
14,707 Views
14 Pages

14 March 2019

Various studies showed that a “one size fits all” dietary recommendation for weight management is questionable. For this reason, the focus increasingly falls on personalised nutrition. Although there is no precise and uniform definition o...

  • Article
  • Open Access
9 Citations
5,766 Views
12 Pages

3 December 2020

Employers in the United States (US) increasingly offer personalized wellness products as a workplace benefit. In doing so, those employers must be cognizant of not only US law but also European Union (EU) law to the extent that the EU law applies to...

  • Review
  • Open Access
2 Citations
4,783 Views
14 Pages

21 December 2024

The COVID-19 pandemic disrupted routine healthcare services, including testing and treatment for sexually transmitted infections (STIs). At the same time, it fostered optimism about the potential of direct-to-consumer (DTC) self-testing solutions, fu...

  • Perspective
  • Open Access
17 Citations
5,878 Views
16 Pages

Virtual Care and the Inverse Care Law: Implications for Policy, Practice, Research, Public and Patients

  • Hassane Alami,
  • Pascale Lehoux,
  • Sara E. Shaw,
  • Chrysanthi Papoutsi,
  • Sarah Rybczynska-Bunt and
  • Jean-Paul Fortin

Virtual care spread rapidly at the outbreak of the COVID-19 pandemic. Restricting in-person contact contributed to reducing the spread of infection and saved lives. However, the benefits of virtual care were not evenly distributed within and across s...

  • Review
  • Open Access
331 Views
24 Pages

Predictive Biomarkers for Asymptomatic Adults: Opportunities, Risks, and Guidance for General Practice

  • Christian J. Wiedermann,
  • Giuliano Piccoliori,
  • Adolf Engl and
  • Doris Hager von Strobele-Prainsack

Biomarker-based prevention is rapidly expanding, driven by advances in molecular diagnostics, genetic profiling, and commercial direct-to-consumer (DTC) testing. General practitioners (GPs) increasingly encounter biomarker results of uncertain releva...

  • Article
  • Open Access
2 Citations
3,638 Views
10 Pages

Does Direct-to-Consumer Personal Genetic Testing Improve Gynecological Cancer Screening Uptake among Never-Screened Attendees? A Randomized Controlled Study

  • Miki Watanabe,
  • Satoyo Hosono,
  • Hiroko Nakagawa-Senda,
  • Sachiyo Yamamoto,
  • Masami Aoyama,
  • Satoru Hattori,
  • Tamaki Yamada and
  • Sadao Suzuki

The clinical impact of direct-to-consumer genetic testing (DTC-GT) on health behavior change has remained controversial. The aim of this study is to clarify the short-term effects of DTC-GT on gynecological cancer screening uptake among middle-aged n...

  • Article
  • Open Access
1,960 Views
14 Pages

Factors Influencing Consumers’ Direct Sale Purchase Intention in the Context of Climate Change

  • Ana Čehić Marić,
  • Ana Težak Damijanić,
  • Tajana Čop,
  • Mario Njavro and
  • Milan Oplanić

22 August 2025

Direct purchasing offers consumers the advantage of fresher, higher-quality food, often at lower prices, with greater transparency in terms of origin and production methods, which creates trust and enables more environmentally conscious choices. On t...

  • Article
  • Open Access
1,056 Views
13 Pages

Decisions, Decisions: Observations of Resource Allocation Under Consumer-Directed Care

  • Danelle Kenny,
  • Kim-Huong Nguyen,
  • Zachary Breig,
  • Lana Friesen and
  • Tracy Comans

27 February 2025

Introduction: Resource trade-offs are a universal feature of decision-making in healthcare. Public funding for home care is an example of a complex resource allocation decision, requiring balance between the needs of the individual and the capacity o...

  • Article
  • Open Access
2 Citations
1,391 Views
24 Pages

12 April 2024

With the development of global clean energy and the implementation of carbon emission reduction policies, the direct purchase of electricity by large consumers has been increasingly promoted as a special form of electricity trading. Therefore, on the...

  • Communication
  • Open Access
2 Citations
3,627 Views
6 Pages

False Alarms in Consumer Genomics Add to Public Fear and Potential Health Care Burden

  • Xiaoming Liu,
  • Deborah Cragun,
  • Jinyong Pang,
  • Swamy R. Adapa,
  • Renee Fonseca and
  • Rays H. Y. Jiang

23 October 2020

We have entered an era of direct-to-consumer (DTC) genomics. Patients have relayed many success stories of DTC genomics about finding causal mutations of genetic diseases before showing any symptoms and taking precautions. However, consumers may also...

  • Article
  • Open Access
8 Citations
7,408 Views
19 Pages

Electric vehicles (EVs) are increasingly recognized as a viable strategy for mitigating energy consumption and reducing greenhouse gas emissions within the transportation sector. In order to facilitate the advancement of EVs, this study expands upon...

  • Article
  • Open Access
5 Citations
3,115 Views
16 Pages

An Agent-Based Two-Stage Trading Model for Direct Electricity Procurement of Large Consumers

  • Jian Zhang,
  • Yanan Zheng,
  • Mingtao Yao,
  • Huiji Wang and
  • Zhaoguang Hu

14 September 2019

Many electricity markets around the world are still at developmental and transitional stages. To complete the transition and achieve the key objectives of perfect market design, designers often choose direct electricity procurement of large consumers...

  • Article
  • Open Access
6 Citations
3,088 Views
15 Pages

24 January 2023

This paper investigates the relationship between geothermal energy consumption, economic growth, and foreign direct investments in countries where geothermal energy production is possible. Panel Fourier Granger causality and panel Fourier Toda–...

  • Technical Note
  • Open Access
1 Citations
2,376 Views
8 Pages

How Much Should Consumers with Mild to Moderate Hearing Loss Spend on Hearing Devices?

  • Vinaya Manchaiah,
  • Steve Taddei,
  • Abram Bailey,
  • De Wet Swanepoel,
  • Hansapani Rodrigo and
  • Andrew Sabin

Background: This study examined the relationship between hearing device price and sound quality. Method: A novel consumer-centric metric of sound quality (“SoundScore”) was used to assess hearing devices’ audio performance. Each hea...

  • Article
  • Open Access
15 Citations
4,930 Views
17 Pages

Consumer Seafood Waste and the Potential of a ‘Direct-from-Frozen’ Approach to Prevention

  • Roni A. Neff,
  • David C. Love,
  • Katie Overbey,
  • Erin Biehl,
  • Jonathan Deutsch,
  • Irena Gorski-Steiner,
  • Pete Pearson,
  • Toriana Vigil,
  • Catherine Turvey and
  • Jillian P. Fry

21 October 2021

Few food waste interventions focus on drivers distinct to particular food groups, such as seafood. Given suggestive evidence that seafood may be wasted at exceptionally high rates, and given its environmental, economic and nutritional value, this res...

  • Article
  • Open Access
2 Citations
4,719 Views
9 Pages

18 October 2022

Background Media coverage of the COVID-19 pandemic increased tuning ratings during this time. The aim of this study was to identify misleading advertising of health-related products on Ecuadorian television during the COVID-19 pandemic. Methods Telev...

  • Article
  • Open Access
2 Citations
3,128 Views
15 Pages

Parents increasingly utilise the internet to obtain information on health practices, but the quality of online information about screening for inherited metabolic diseases (IMD) needs to be improved. A content analysis examined how IMD blood and urin...

  • Article
  • Open Access
14 Citations
5,511 Views
11 Pages

Hearing Healthcare Professionals’ Views about Over-The-Counter (OTC) Hearing Aids: Analysis of Retrospective Survey Data

  • Vinaya Manchaiah,
  • Anu Sharma,
  • Hansapani Rodrigo,
  • Abram Bailey,
  • Karina C. De Sousa and
  • De Wet Swanepoel

1 March 2023

Over-the-counter hearing aids have been available to consumers in the US since 17 October 2022 following a ruling by the Food and Drug Administration. However, their reception by hearing healthcare professionals (HHP) has been mixed, and concerns hav...

  • Review
  • Open Access
37 Citations
10,091 Views
13 Pages

Local food has been the subject of federal, state, and local government policies in recent years throughout the United States as consumer demand has grown. Local foods have been linked to several government priorities—including enhancing the rural ec...

  • Article
  • Open Access
8 Citations
4,539 Views
12 Pages

12 November 2018

It remains unknown whether and how sports medicine physicians currently utilize genetic testing in their clinical practice. This study sought to assess knowledge of, experience with, and attitudes towards genetic testing by sports medicine physicians...

  • Article
  • Open Access
35 Citations
8,652 Views
21 Pages

Gaining and Maintaining a Competitive Edge: Evidence from CSA Members and Farmers on Local Food Marketing Strategies

  • Emily H. Morgan,
  • Michelle M. Severs,
  • Karla L. Hanson,
  • Jared McGuirt,
  • Florence Becot,
  • Weiwei Wang,
  • Jane Kolodinsky,
  • Marilyn Sitaker,
  • Stephanie B. Jilcott Pitts and
  • Rebecca A. Seguin
  • + 1 author

26 June 2018

Community-supported agriculture (CSA) is a widely-used approach for farmers to sell directly to consumers. We used the product, place, price, and promotion (4P) marketing mix framework to examine characteristics that help farms offering CSA maintain...

  • Article
  • Open Access
25 Citations
9,143 Views
15 Pages

16 February 2023

The increase in plastic recycling is an essential pre-requisite for the transition to a circular economy. Polystyrene (PS) is a low diffusive polymer and therefore a promising candidate for recycling back into food contact similar to polyethylene ter...

  • Article
  • Open Access
26 Citations
7,074 Views
12 Pages

Direct Effects of the Home, School, and Consumer Food Environments on the Association between Food Purchasing Patterns and Dietary Intake among Rural Adolescents in Kentucky and North Carolina, 2017

  • Alison Gustafson,
  • Stephanie Jilcott Pitts,
  • Jordan McDonald,
  • Hannah Ford,
  • Paige Connelly,
  • Rachel Gillespie,
  • Emily Liu,
  • Heather Bush,
  • Candace Brancato and
  • Janet Mullins
  • + 1 author

Background: Obesity rates are higher among rural versus urban adolescents. To examine possible mechanisms for the rural-urban adolescent obesity disparity, we examined the direct and indirect effects of food purchasing patterns, and the home, school,...

  • Article
  • Open Access
6 Citations
4,751 Views
18 Pages

A complexity of factors, from health and technology innovations to policy redesign to achieve consumer-directed care, are impacting traditional roles for Australian allied health practitioners (AHPs). This pilot study considers roles for AHPs in rela...

  • Article
  • Open Access
54 Citations
6,453 Views
14 Pages

Relations between Circular Economic “Principles” and Organic Food Purchasing Behavior in Hungary

  • Csaba Fogarassy,
  • Kinga Nagy-Pércsi,
  • Sinazo Ajibade,
  • Csaba Gyuricza and
  • Prespa Ymeri

26 April 2020

Because of the climate change and emerging need for an environmentally sustainable production system, circular economic characteristics have come to the front in many studies. There are many challenges in this shift toward a circular value chain. Sti...

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