A mathematical model was developed to describe batch and continuous fermentation of glucose to organic acids with Clostridium tyrobutyricum. A modified Monod equation was used to describe cell growth, and a Luedeking-Piret equation was used to descri...
Cupriavidus necator can produce single-cell proteins (SCPs) using electrons produced by hydrogen as energy, oxygen as electron acceptors, and CO2 as carbon sources. Gas fermentation is a process of microbial fermentation that uses gas substrates (suc...
For the fermentation of vinegar using onion, acetic acid bacteria and yeast strains with high fermentation ability were screened. Among them, Saccharomyces cerevisiae 1026 was selected as a starter for ethanol production and Acetobacter orientalis MA...
Membrane bioreactor systems can enhance anaerobic lactic acid fermentation by reducing product inhibition, thus increasing productivity. In batch fermentations, the bioconversion of glucose is strongly inhibited in the presence of more than 100 g·L−1...
The main problems with the butanol fermentation process include high cost of grain raw materials, low product concentration and low butanol productivity caused by butanol cytotoxicity. In this study, cassava, a cheap crop, was used as the raw materia...
The utilisation of waste materials and industrial residues became a priority within the bioeconomy concept and the production of biobased chemicals. The aim of this study was to evaluate the feasibility to continuously produce L-lactic acid from diff...
Acetone–butanol–ethanol (ABE) fermentation is influenced by external conditions. This work aimed to study the influence of pH regulation on monosaccharide composition in batch and continuous fermentation processes to determine butanol pro...
The application of continuous fermentation with immobilized cells in brewing is a challenge because of problems with carrier selection and reactor design, which have economic impacts on the beer produced. Moreover, immobilization alters yeast physiol...
The overall objective of this study was to determine the dose response to four levels of cashew nut shell extract in a granulated form (CNSE, containing 59% anacardic acid and 18% cardol) on culture pH, rumen fermentation metabolites, and apparent nu...
In making alternative fuels from biomass feedstocks, the production of butyric acid is a key intermediate in the two-step production of butanol. The fermentation of glucose via Clostridium tyrobutyricum to butyric acid produces undesirable byproducts...
Despite the current appreciation of pulque as a probiotic fermented beverage, pulque has been also regarded as a poor-quality product, particularly due to the lack of sanitary control during its elaboration. To address this problem, a semi-continuous...
The use of metal nanoparticles (NPs) to enhance hydrogen production in dark fermentation (DF) has become a pioneering field of interest. In particular, iron-based nanoparticles (FeNPs) play a pivotal role in enhancing the activity of metalloenzymes a...
Caffeine is a plant secondary metabolite, commonly known for its bioactivity properties. This molecule increases microbial activity during anaerobic digestion. The aim of this study was to determine the effects of caffeine doses on the rumen fermenta...
Continuous ethanol fermentation is crucial for renewable bio-manufacturing, but delay-induced ethanol inhibition triggers self-oscillations via Hopf bifurcations, undermining productivity and stability. This study investigates instability mechanisms...
The diversity and the stability of the microbial community are associated with microecological interactions between its members. Antagonism is one type of interaction, which particularly determines the benefits that probiotics bring to host health by...
For pollution control and waste utilization, a promising future direction is to obtain high-value carbon sources from organic waste. In this experiment, swine manure was efficiently converted into high concentration volatile fatty acids through conti...
The production of butanol, acetone and ethanol by Clostridium acetobutylicum is a biphasic fermentation process. In the first phase the carbohydrate substrate is metabolized to acetic and butyric acid, in the following second phase the product spectr...
Two methanogenesis inhibition strategies for enhancing volatile fatty acid (VFA) production through the anaerobic fermentation of alperujo, a byproduct of olive oil production, were evaluated. Methanogenesis inhibition was implemented via two differe...
Biofilms can enhance industrial fermentation efficiency by increasing cell density, stability, and metabolic activity and have been successfully applied to the continuous production of many small-molecule chemicals. However, the continuous production...
We have established a two-stage continuous fermentation process for production of ethanol from synthesis gas (syngas) with Clostridium ljungdahlii. The system consists of a 1-L continuously stirred tank reactor as a growth stage and a 4-L bubble co...
Computational modeling and the theory of nonlinear dynamical systems allow us not only to simply describe the events of biochemical oscillators in the ethanol fermentation process but also to understand why these events occur. This article reviews re...
Traditional batch ethanol fermentation poses the problems of poor production and economic viability because the lag and stationary phase always demand considerable fermentation time; plus, downtime between batches is requested to harvest, clean, and...
Dough fermentation is an important step during the preparation of fermented baking goods. For the supervision of dough fermentation, a continuous-discrete extended Kalman filter was applied, which uses an image analysis system as the measurement. By...
A novel approach to improve ethanol production from sugarcane bagasse is proposed. Biomass was pretreated with sodium hydroxide, sulfuric, oxalic, and maleic acids (1% w/v) at different temperatures (130–170 °C) and times (10–30 min)....
Syngas fermentation is a promising carbon capture and utilization (CCU) technology for producing carboxylic acids while transforming low-cost waste gas into high-value products. This study evaluates the two bioreactor feeding strategies for synthesis...
When cassava is used for the production of distilled spirits through fermentation and distillation, toxic hydrogen cyanide (HCN) is released from linamarin and carcinogenic ethyl carbamate is produced. Herein, cyanide and ethyl carbamate contents wer...
This study investigates the efficient biogenic production of hydrogen via the thermophilic bacterium Thermotoga neapolitana, focusing on optimising process configurations to maximise yield and productivity. To determine optimal conditions, a 1 L anae...
Food waste (FW) valorization via lactic acid (LA) fermentation is a promising approach, yet most studies rely on surrogate substrates, limiting industrial applicability. This study investigated continuous LA fermentation of actual FW slurry from a Sh...
The aim of this study was to distinguish effects due to diet composition from those triggered by ruminal pH on fermentation patterns and microbial profiles in a continuous culture system (RUSITEC). The study followed a 2 × 2 factorial design, w...
Lignocellulose biorefinery via continuous cell-recycle fermentation has long been recognized as a promising alternative technique for producing chemicals. ᴅ-lactic acid (D-LA) production by fermentation of corn stover by Lactobacillus bulgaricu...
Human epidermal growth factor (hEGF) holds significant importance in the fields of medicine and cosmetics. Therefore, it becomes imperative to develop a highly efficient fermentation system for hEGF production. In this study, a stable hEGF-secreting...
Nowadays, continuous monitoring is a difficult issue in microscopy. A chip-sized microscope was developed, composed only of microelectronic components, with high optical resolution and a wide field of view. Due to its miniaturized size, it can be pla...
Protocatechuate acid (PCA) is a phenolic acid naturally synthesized by various organisms. Protocatechuic acid is synthesized by plants for physiological, metabolic functions, and self-defense, but extraction from plants is less efficient compared to...
The aim of the study was to evaluate the possibility of using the process of dark fermentation to convert kitchen waste into valuable volatile fatty acids in a semi-continuous process at different values of the organic loading rate (2.5 and 5.0 gVS/(...
Syngas fermentation can play an important role in implementing the concept of biorefinery as it can serve as a platform to convert high-lignin biomass to biofuels. For the utilization of this process in commercial scale, the generation of an experime...
This study aimed to evaluate the effect of enzymatic hydrolysate of cottonseed protein (ECP) on the kinetic of gas production, rumen fermentation characteristics, and microbial diversity in continuous in vitro culture with a single factorial design o...
Optimization of the continuous fermentation process is important for increasing efficiency and decreasing cost, especially for complicated biochemical processes described by substrate and product inhibition. The optimum design (minimum volume) of CST...
Here, a comprehensive investigation was conducted under various operational strategies aimed at enhancing biohydrogen production via dark fermentation, with a specific focus on the lactate metabolic pathway, using powdered cheese whey as a substrate....
Aflatoxin B1 (AFB1) is a mycotoxin known to impair human and animal health. It is also believed to have a deleterious effect on ruminal nutrient digestibility under in vitro batch culture systems. The objective of this study was to evaluate the effec...
To fulfill the consumption demand of low-cost fuel ethanol, an advanced process for feedstock fermentation and bioethanol extraction was required. This study proposed a process of combined continuous solid-state distillation and vapor permeation to e...
Syngas (mixture of CO, H2 and CO2) fermentation suffers from mass transfer limitation due to low solubility of CO and H2 in the liquid medium. Therefore, it is critical to characterize the mass transfer in syngas fermentation reactors to guide in del...
Fecal microbiota transplantation (FMT) is an alternative method for the treatment of gastrointestinal diseases with a high recovery rate. Disadvantages are ethical concerns, high donor requirements and the low storability of stool samples. The cultiv...
Recently, the extensive spread of some algae along coastlines has surged into unmanageable thick decomposition layers. This study aimed to demonstrate the use of Sargassum horneri as a biomass resource for ethanol production through the continuous hy...
A trickle-bed reactor (TBR) when operated in a trickle flow regime reduces liquid resistance to mass transfer because a very thin liquid film is in contact with the gas phase and results in improved gas–liquid mass transfer compared to continuous sti...
Syngas biomethanation is a potent bio-conversion route, utilizing microorganisms to assimilate intermediate gases to produce methane. However, since methanogens have a long doubling time, the reactor works best at a low dilution rate; otherwise, the...
This study aims to integrate a novel bio-purification process employing an engineered E. coli strain in the downstream processing of lactic acid (LA) fermentation broths from low-cost renewable biological feedstocks. Fermentation broth of candy waste...
Biogas plants can contribute to future energy systems’ stability through flexible power generation. To provide power flexibly, a demand-oriented biogas supply is necessary, which may be ensured by applying flexible feeding strategies. In this s...
The utilization of rice straw for biofuel production is limited by its composition. The pretreatment process is required to improve the enzymatic accessibility of polysaccharides in the biomass prior to enzymatic saccharification. In this study, simu...
Syngas fermentation with clostridial co-cultures is promising for the conversion of CO to alcohols. A CO sensitivity study with Clostridium kluyveri monocultures in batch operated stirred-tank bioreactors revealed total growth inhibition of C. kluyve...
Clostridia are interesting candidates for biotechnological applications due to their diverse and unique metabolic abilities. Particularly in continuous fermentation processes, productivity-decreasing metabolic oscillations have been reported in many...
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