Background and Objectives: Although the technical simplicity of laparoscopic sleeve gastrectomy is relatively well understood, many parts of the procedure differ according to bariatric surgeons. These technical variations may impact postoperative wei...
The branched-chain amino acids (BCAAs) leucine, isoleucine and valine are synthesized via a common biosynthetic pathway. Ketol-acid reductoisomerase (KARI) is the second enzyme in this pathway. In addition to its role in BCAA biosynthesis, KARI catal...
Polyethylene terephthalate (PET) is the most widely used polyester plastic, with applications in the textile and packaging industry. Currently, re-moulding is the main path for PET recycling, but this eventually leads to an unsustainable loss of qual...
In this study, we propose a virtual reality biphasic separator methodology in an immersive industrial environment. It allows the training of students or engineers in process and automatic control. On the other hand, the operating performance of a bip...
Human butyrylcholinesterase is a performant stoichiometric bioscavenger of organophosphorous nerve agents. It is either isolated from outdated plasma or functionally expressed in eukaryotic systems. Here, we report the production of active human buty...
Tracking the cell temperature is critical for battery safety and cell durability. It is not feasible to equip every cell with a temperature sensor in large battery systems such as those in electric vehicles. Apart from this, temperature sensors are u...
Objectives: The aim of this study was to compare the level of discrimination among patients with obesity living in Poland and Germany. Methods: This was a retrospective cross-sectional international multicenter survey study including 564 adult partic...
7 July 2022
In preparation for the PRO B study which aims to examine the effects of an app-based intensified patient-reported outcome (PRO) monitoring for metastatic breast cancer patients, prior assessment of its feasibility was carried out. Sixteen breast canc...
The central thesis of the modern scientific revolution is that nature is objective. Yet, somehow, out of that objective reality, projective systems emerged—cognitive and purposeful. More remarkably, through nature’s objective laws, chemical systems e...
One of life’s most striking characteristics is its mental dimension, one whose very existence within a material system has long been a deep scientific mystery. Given the current scientific view that life emerged from non-life, how was it possib...
The temperature in each cell of a battery system should be monitored to correctly track aging behavior and ensure safety requirements. To eliminate the need for additional hardware components, a software based prediction model is needed to track the...
Animal-Assisted Services (AASs) are increasingly used in therapeutic, educational, and supportive contexts, raising growing concern for the welfare of the dogs involved. This study assessed dogs’ affective states during AAS sessions by establis...
Animal-assisted services (AASs) are increasingly integrated into healthcare, education, and social support settings. However, empirical evidence on the emotional well-being of participating dogs remains limited. This study investigates how dog, sessi...
Since Sony launched the commercial lithium-ion cell in 1991, the composition of the liquid electrolytes has changed only slightly. The electrolyte consists of highly flammable solvents and thus poses a safety risk. Solid-state ion conductors, classif...
We review the concept of dynamic kinetic stability, a type of stability associated specifically with replicating entities, and show how it differs from the well-known and established (static) kinetic and thermodynamic stabilities associated with regu...
Attention deficit hyperactivity disorder (ADHD) is a common pediatric psychiatric disorder, frequently treated with methylphenidate (MPH). Recently, MPH’s cardiovascular safety has been questioned by observational studies describing an increase...
Equine-Assisted Services (EAS) offer significant benefits for individuals with intellectual and/or physical disabilities. However, ensuring the welfare of the horses involved remains a key ethical concern. The objective of this study was to assess th...
This work addresses the kinetic requirements for compensating the entropic cost of self-organization and natural selection, thereby revealing a fundamental principle in biology. Metabolic and evolutionary features of life cannot therefore be separate...
The energy transition is only feasible by using household or large photovoltaic powerplants. However, efficient use of photovoltaic power independently of other energy sources can only be accomplished employing batteries. The ever-growing demand for...
In this paper, we investigate different current collector materials for in situ deposition of lithium using a slurry-based
This study aimed to investigate and compare the adherence of patients treated for morbid obesity living in Poland and Germany. Methods: A cross-sectional international multicenter survey design was adopted. The study involved 564 adult subjects treat...
Background: Relapse is the leading cause of treatment failure in patients with myeloid hematologic malignancies undergoing allogeneic hematopoietic cell transplantation. Clonal genomic evolution may contribute to post-transplant relapse, yet its dete...
AlphaFold2 (AF2) is a protein structure prediction program which provides accurate models. In addition to predicting structural domains, AF2 assigns intrinsically disordered regions (IDRs) by identifying regions with low prediction reliability (pLDDT...
Osteochondritis dissecans (OCD) of the knee is an uncommon injury in young active patients. There is currently a lack of knowledge regarding clinical outcomes and return-to-sport rates after fragment fixation surgery using hydroxy appetite poly-L-lac...
The isolation of nanobodies from pre-immune libraries by means of biopanning is a straightforward process. Nevertheless, the recovered candidates often require optimization to improve some of their biophysical characteristics. In principle, CDRs are...
Conventional qualitative eye movement examinations may miss subtle abnormalities, complicating early and accurate diagnosis of progressive supranuclear palsy (PSP). Quantitative oculography, represented by video-oculography (VOG), provides an objecti...
The assignment of secondary structure elements in proteins is a key step in the analysis of their structures and functions. We have developed an algorithm, SACF (secondary structure assignment based on Cα fragments), for secondary structure element (...
In the degradation of poly(ethylene terephthalate) (PET), mono(2-hydroxyethyl) terephthalate (MHET) hydrolase (IsMHETase) plays a crucial role in the complete degradation of PET. Although IsMHETase was discovered concurrently with IsPETase, its struc...