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399 Results Found

  • Communication
  • Open Access
9 Citations
7,105 Views
13 Pages

15 April 2024

The insecticide known as neonicotinoid has negative impacts on the ecosystem, human health, and the environment; specifically, its effects on the relationship between crop yields and the death rate of natural pollinators, such as bees, affect food se...

  • Review
  • Open Access
44 Citations
7,860 Views
12 Pages

14 October 2019

Acetylcholine is the main excitatory neurotransmitter in the honeybee brain and controls a wide range of behaviours that ensure the survival of the individuals and of the entire colony. Neonicotinoid pesticides target this neurotransmission pathway a...

  • Article
  • Open Access
1 Citations
2,651 Views
12 Pages

Characterization of Neonicotinoid Metabolites by Cytochrome P450-Mediated Metabolism in Poultry

  • Adisorn Dam-on,
  • Collins Nimako,
  • Sittinee Kulprasertsri,
  • Yoshinori Ikenaka,
  • Yared B. Yohannes,
  • Shouta M. M. Nakayama,
  • Mayumi Ishizuka,
  • Saranya Poapolathep,
  • Amnart Poapolathep and
  • Kraisiri Khidkhan

21 August 2024

Neonicotinoids, a neuro-effective class of insecticides, are heavily applied in agricultural activities worldwide. Poultry can be exposed to neonicotinoids by several routes, but the knowledge of neonicotinoid’s metabolism in poultry and its as...

  • Review
  • Open Access
140 Citations
13,954 Views
17 Pages

Literature Review: Global Neonicotinoid Insecticide Occurrence in Aquatic Environments

  • Josephus F. Borsuah,
  • Tiffany L. Messer,
  • Daniel D. Snow,
  • Steve D. Comfort and
  • Aaron R. Mittelstet

2 December 2020

Neonicotinoids have been the most commonly used insecticides since the early 1990s. Despite their efficacy in improving crop protection and management, these agrochemicals have gained recent attention for their negative impacts on non-target species...

  • Article
  • Open Access
9 Citations
2,962 Views
16 Pages

Neonicotinoid Microsphere Immunosensing for Profiling Applications in Honeybees and Bee-Related Matrices

  • Mang Xu,
  • Liza Portier,
  • Toine Bovee,
  • Ying Zhao,
  • Yirong Guo and
  • Jeroen Peters

26 September 2022

Neonicotinoids are the most commonly used insecticides due to their effectiveness. However, non-targeted insects, especially bees, are also affected by neonicotinoids. Therefore, neonicotinoid application can contribute to the declining bee populatio...

  • Communication
  • Open Access
3 Citations
2,999 Views
11 Pages

12 January 2024

Toxicological studies have shown that the American cockroach Periplaneta americana (Linnaeus) is a classical model for studying the mode of action of commonly used insecticides. In a previous study, we demonstrated that thiamethoxam and clothianidin...

  • Review
  • Open Access
60 Citations
8,682 Views
16 Pages

Screening of Toxic Effects of Neonicotinoid Insecticides with a Focus on Acetamiprid: A Review

  • Lucia Zuščíková,
  • Denis Bažány,
  • Hana Greifová,
  • Nikola Knížatová,
  • Anton Kováčik,
  • Norbert Lukáč and
  • Tomáš Jambor

8 July 2023

Recently, neonicotinoids have become the fastest-growing class of insecticides in conventional crop protection, with extensive usage against a wide range of sucking and chewing pests. Neonicotinoids are widely used due to their high toxicity to inver...

  • Article
  • Open Access
4 Citations
3,030 Views
14 Pages

Investigation of the Effects of Probiotics on Sub-Chronic Neonicotinoid Toxicity in Rats

  • Cigdem Sevim,
  • Erol Akpinar,
  • Aristides Tsatsakis,
  • Serkan Yildirim,
  • Manolis Tzatzarakis,
  • Alexander I. Vardavas,
  • Constantine I. Vardavas,
  • Mehtap Kara and
  • Zulfiye Gul

3 October 2021

Probiotics have been shown to have positive effects when it comes to combating various health issues when consumed, preventing even the absorption of environmental toxins. One of the main environmental toxins encountered today is pesticide residues....

  • Review
  • Open Access
1,702 Views
16 Pages

9 July 2025

Neonicotinoids are extensively used in agricultural production, yet increasing evidence highlights their cytotoxic effects on various cell types. Research has demonstrated that these pesticides can significantly impair the viability and function of r...

  • Article
  • Open Access
14 Citations
5,013 Views
10 Pages

12 June 2020

Consistent with the large-scale use of pesticide seed treatments in U.S. field crop production, there has been an increased use of neonicotinoid-treated corn and soybean seed over the past decade. Neonicotinoids can move downwind to adjacent off-fiel...

  • Article
  • Open Access
5 Citations
3,296 Views
13 Pages

Temporal Profile of Neonicotinoid Concentrations in Cotton, Corn, and Soybean Resulting from Insecticidal Seed Treatments

  • Adam Whalen,
  • Angus L. Catchot,
  • Jeff Gore,
  • Scott D. Stewart,
  • Gus M. Lorenz,
  • Donald R. Cook,
  • Fred R. Musser,
  • Jeffrey W. Harris and
  • Natraj Krishnan

12 June 2021

Neonicotinoids have been implicated as a contributing factor to the observed decreases in honey bee populations. It has been suggested that honey bees can be exposed to seed-treated neonicotinoids through pollen and nectar from treated plants. To inv...

  • Article
  • Open Access
3 Citations
2,295 Views
12 Pages

Effects of Neonicotinoid Seed Treatments on Cotton Seedling Physiology, Nutrition, and Growth

  • Aqeela Sehrish,
  • Megha Parajulee,
  • Suhas Vyavhare,
  • Cade Coldren,
  • Haydee Laza and
  • Catherine R. Simpson

11 April 2024

Plant growth and physiology can be affected by environmental and chemical factors that have the potential to influence yields. Among the factors that influence plant growth, neonicotinoid seed treatments have shown significant effects on plant growth...

  • Review
  • Open Access
81 Citations
14,939 Views
35 Pages

Physiological Effects of Neonicotinoid Insecticides on Non-Target Aquatic Animals—An Updated Review

  • Nemi Malhotra,
  • Kelvin H.-C. Chen,
  • Jong-Chin Huang,
  • Hong-Thih Lai,
  • Boontida Uapipatanakul,
  • Marri Jmelou M. Roldan,
  • Allan Patrick G. Macabeo,
  • Tzong-Rong Ger and
  • Chung-Der Hsiao

4 September 2021

In this paper, we review the effects of large-scale neonicotinoid contaminations in the aquatic environment on non-target aquatic invertebrate and vertebrate species. These aquatic species are the fauna widely exposed to environmental changes and che...

  • Article
  • Open Access
15 Citations
3,797 Views
19 Pages

Detection of Changes in Monoamine Neurotransmitters by the Neonicotinoid Pesticide Imidacloprid Using Mass Spectrometry

  • Anri Hirai,
  • Ryo Yamazaki,
  • Atsushi Kobayashi,
  • Takashi Kimura,
  • Kei Nomiyama,
  • Shuichi Shimma,
  • Shouta M. M. Nakayama,
  • Mayumi Ishizuka and
  • Yoshinori Ikenaka

17 November 2022

Monoamine neurotransmitters (MAs), including dopamine (DA) and serotonin (5-HT), regulate brain functions such as behavior, memory, and learning. Neonicotinoids are pesticides that are being used more frequently. Neonicotinoid exposure has been obser...

  • Review
  • Open Access
54 Citations
11,376 Views
11 Pages

Neonicotinoid insecticides are used worldwide and have been demonstrated as toxic to beneficial insects such as honeybees. Their effectiveness is predominantly attributed to their high affinity for insect neuronal nicotinic acetylcholine receptors (n...

  • Article
  • Open Access
10 Citations
4,891 Views
12 Pages

Synthesis and Biological Activity Evaluation of Novel β-Substituted Nitromethylene Neonicotinoid Analogues

  • Baozhu Wang,
  • Jiagao Cheng,
  • Zhiping Xu,
  • Xiaoyong Xu,
  • Xusheng Shao and
  • Zhong Li

24 August 2012

The structure-based design and synthesis of a series of novel neonicotinoid analogues are described. The novel neonicotinoid analogues were designed based upon the reaction of enamine derivatives with electron-withdrawing β-substituents with electrop...

  • Article
  • Open Access
34 Citations
11,207 Views
27 Pages

Neonicotinoid Insecticides Alter the Gene Expression Profile of Neuron-Enriched Cultures from Neonatal Rat Cerebellum

  • Junko Kimura-Kuroda,
  • Yasumasa Nishito,
  • Hiroko Yanagisawa,
  • Yoichiro Kuroda,
  • Yukari Komuta,
  • Hitoshi Kawano and
  • Masaharu Hayashi

Neonicotinoids are considered safe because of their low affinities to mammalian nicotinic acetylcholine receptors (nAChRs) relative to insect nAChRs. However, because of importance of nAChRs in mammalian brain development, there remains a need to est...

  • Article
  • Open Access
20 Citations
4,207 Views
16 Pages

Ultrasonically Modified Amended-Cloud Point Extraction for Simultaneous Pre-Concentration of Neonicotinoid Insecticide Residues

  • Rawikan Kachangoon,
  • Jitlada Vichapong,
  • Rodjana Burakham,
  • Yanawath Santaladchaiyakit and
  • Supalax Srijaranai

An effective pre-concentration method, namely amended-cloud point extraction (CPE), has been developed for the extraction and pre-concentration of neonicotinoid insecticide residues. The studied analytes including clothianidin, imidacloprid, acetamip...

  • Article
  • Open Access
9 Citations
2,884 Views
13 Pages

Trace Immunosensing of Multiple Neonicotinoid Insecticides by a Novel Broad-Specific Antibody Obtained from a Rational Screening Strategy

  • Shasha Jiao,
  • Yan Wang,
  • Yunyun Chang,
  • Pengyan Liu,
  • Yang Chen,
  • Yihua Liu,
  • Guonian Zhu and
  • Yirong Guo

3 September 2022

Residues of neonicotinoid pesticides have potential risks to food, environmental and biological safety. In this study, the hapten toward imidacloprid was adopted to gain antibodies. After molecular modeling, the electrostatic potentials of eight comm...

  • Article
  • Open Access
1 Citations
1,508 Views
12 Pages

Residue Analysis and Dietary Risk Assessment of 10 Neonicotinoid Insecticides in Oenanthe javanica from Hainan Province of China

  • Shusheng Tang,
  • Zikang Zeng,
  • Rui Kang,
  • Ying Wei,
  • Gaohao Tan,
  • Minni Chen,
  • Bin Wang and
  • Zhuhua Tang

31 December 2024

In this study, residues of 10 neonicotinoid insecticides were tested with 143 fresh samples of Oenanthe javanica using the QuEChERS method combined with UPLC-MS/MS. Based on the residue results, the point estimation method was used to assess dietary...

  • Article
  • Open Access
2 Citations
1,652 Views
17 Pages

Behavioral Responses of Unio tumidus Freshwater Mussels to Neonicotinoid Pesticide Contamination

  • Marta Szostak,
  • Krzysztof Szoszkiewicz,
  • Krzysztof Achtenberg and
  • Dariusz Drożdżyński

21 January 2025

This investigation examined the behavioral responses of freshwater mussels to neonicotinoid pesticide exposure, a widely implemented agricultural crop protection agent. The study systematically evaluated the behavioral modifications of U. tumidus und...

  • Article
  • Open Access
23 Citations
6,043 Views
16 Pages

Neonicotinoid Residues in Sugar Beet Plants and Soil under Different Agro-Climatic Conditions

  • Helena Viric Gasparic,
  • Mirela Grubelic,
  • Verica Dragovic Uzelac,
  • Renata Bazok,
  • Maja Cacija,
  • Zrinka Drmic and
  • Darija Lemic

19 October 2020

European sugar beet was mostly grown from seeds treated by neonicotinoids which provided efficient control of some important sugar beet pests (aphids and flea beetles). The EU commission regulation from 2018 to ultimately restrict the outdoor applica...

  • Communication
  • Open Access
2 Citations
2,855 Views
8 Pages

2 September 2022

Neonicotinoids are pesticides widely used for pest control in agriculture with undesirable effects on pollinators. However, other beneficial insects are exposed to insecticides that are not lethal to them but may accumulate and affect their vital cha...

  • Communication
  • Open Access
5 Citations
2,856 Views
9 Pages

23 November 2023

Neonicotinoids, including imidacloprid, are pesticides that resemble nicotine and undergo slight chemical alterations through metabolic changes in the environment. However, the effects of these metabolites on organisms remain unknown. In this study,...

  • Article
  • Open Access
19 Citations
4,808 Views
12 Pages

13 September 2021

The functional expression of the cockroach Pameα7 nicotinic acetylcholine receptor subunit has been previously studied, and was found to be able to form a homomeric receptor when expressed in Xenopus laevis oocytes. In this study, we found that the n...

  • Article
  • Open Access
22 Citations
4,170 Views
12 Pages

Determination of Neonicotinoid Pesticides in Propolis with Liquid Chromatography Coupled to Tandem Mass Spectrometry

  • Rok Tomšič,
  • David Heath,
  • Ester Heath,
  • Jernej Markelj,
  • Andreja Kandolf Borovšak and
  • Helena Prosen

11 December 2020

In this study, a method was developed for the determination of five neonicotinoid pesticides (acetamiprid, clothianidin, imidacloprid, thiacloprid, and thiamethoxam) in propolis. Two sample preparation methods were tested: solid-phase extraction and...

  • Article
  • Open Access
1,432 Views
19 Pages

27 November 2024

The green peach aphid, Myzus persicae, is a notorious pest worldwide. We collected a field population of the pest (FZQ-F) that exhibited high resistance to neonicotinoids. Exposure to neonicotinoids can induce oxidative damage in animals; however, it...

  • Article
  • Open Access
9 Citations
4,008 Views
14 Pages

Efficacy of Two Neonicotinoid Insecticides against Invasive Wood Borer Aromia bungii Larvae in Dietary Toxicity Test

  • Eiriki Sunamura,
  • Shigeaki Tamura,
  • Hisatomo Taki,
  • Hiroki Sato,
  • Etsuko Shoda-Kagaya and
  • Tadahisa Urano

29 June 2021

In recent years, insecticide trunk injection was put into practical use for controlling wood boring pests. However, few studies have investigated the dose–response relationships between insecticides and wood–boring pests in detail. This study used tw...

  • Article
  • Open Access
4 Citations
4,131 Views
21 Pages

Neonicotinoid pesticides (NEOs) were initially considered viable alternatives to conventional organo-pesticides extensively used in agriculture, horticulture, and households. However, the increased frequency and concentration of NEOs in waterways hav...

  • Article
  • Open Access
9 Citations
2,883 Views
10 Pages

Automated Photochemically Induced Method for the Quantitation of the Neonicotinoid Thiacloprid in Lettuce

  • J. Jiménez-López,
  • E.J. Llorent-Martínez,
  • S. Martínez-Soliño and
  • A. Ruiz-Medina

12 November 2019

In this work, we present an automated luminescence sensor for the quantitation of the insecticide thiacloprid, one of the main neonicotinoids, in lettuce samples. A simple and automated manifold was constructed, using multicommutated solenoid valves...

  • Article
  • Open Access
714 Views
39 Pages

A Decision-Support Grid for Evaluating Neonicotinoid Alternatives Based on Environmental and Human Health Impact

  • Michael Raimondi,
  • Edelbis Dávila López,
  • Laura Peeters,
  • Wim Reybroeck,
  • Tim Belien,
  • Dany Bylemans,
  • Jeroen Buysse,
  • Benny De Cauwer and
  • Pieter Spanoghe

15 October 2025

The European Union’s goal to reduce pesticide risk, exemplified by restrictions on insecticides like neonicotinoids, necessitates a shift from single-substance risk assessment to a holistic evaluation of pest control strategies. To address this...

  • Article
  • Open Access
19 Citations
7,611 Views
10 Pages

1 September 2019

The monarch butterfly in North America has suffered a serious population decline since the mid-1990s. The introduction and widespread use of neonicotinoid insecticides during the same time period has been suggested as a potential driver of this decli...

  • Article
  • Open Access
14 Citations
2,932 Views
14 Pages

Metal organic framework based mixed matrix membranes (MOF-MMMs) were synthesized and applied for dispersive membrane extraction (DME) of four neonicotinoid insecticides (nitenpyram, thiacloprid, imidacloprid, and acetamiprid) in environmental water,...

  • Article
  • Open Access
17 Citations
6,689 Views
11 Pages

Mesoionic pyrido[1,2-α]pyrimidinone derivatives containing a neonicotinoid moiety were designed, synthesized, and evaluated for their insecticidal activity. Some of the title compounds showed remarkable insecticidal properties against Aphis cra...

  • Article
  • Open Access
9 Citations
2,998 Views
22 Pages

31 July 2024

Neonicotinoids are synthetic, nicotine-derived insecticides used worldwide to protect crops and domestic animals from pest insects. The reported evidence shows that they are also able to interact with mammalian nicotine receptors (nAChRs), triggering...

  • Article
  • Open Access
58 Citations
8,213 Views
16 Pages

Bismuth Modified Carbon-Based Electrodes for the Determination of Selected Neonicotinoid Insecticides

  • Valéria Guzsvány,
  • Zsigmond Papp,
  • Jasmina Zbiljić,
  • Olga Vajdle and
  • Marko Rodić

27 May 2011

Two types of bismuth modified electrodes, a bismuth-film modified glassy carbon (BiF-GCE) and a bismuth bulk modified carbon paste, were applied for the determination of selected nitroguanidine neonicotinoid insecticides. The method based on an ex si...

  • Article
  • Open Access
25 Citations
4,706 Views
11 Pages

Matrix-Induced Sugaring-Out: A Simple and Rapid Sample Preparation Method for the Determination of Neonicotinoid Pesticides in Honey

  • Wenbin Chen,
  • Siyuan Wu,
  • Jianing Zhang,
  • Fengjie Yu,
  • Jianbo Hou,
  • Xiaoqing Miao and
  • Xijuan Tu

30 July 2019

In the present work, we developed a simple and rapid sample preparation method for the determination of neonicotinoid pesticides in honey based on the matrix-induced sugaring-out. Since there is a high concentration of sugars in the honey matrix, the...

  • Article
  • Open Access
6 Citations
6,544 Views
13 Pages

1 December 2014

Rice in the U.S. is frequently seeded at low rates and treated before sowing with neonicotinoid or anthranilic diamide insecticides to target the rice water weevil. A previous study of the influence of seeding rate on rice water weevil densities show...

  • Review
  • Open Access
21 Citations
4,312 Views
19 Pages

Effect of Neonicotinoid Pesticides on Japanese Water Systems: Review with Focus on Reproductive Toxicity

  • Hayato Terayama,
  • Kou Sakabe,
  • Daisuke Kiyoshima,
  • Ning Qu,
  • Tsutomu Sato,
  • Kaori Suyama,
  • Shogo Hayashi,
  • Kenichi Sakurai,
  • Emiko Todaka and
  • Chisato Mori

30 September 2022

Neonicotinoid pesticides (NPs) are neurotoxic substances. They are highly effective as insecticides owing to their water solubility, permeability, and long-lasting activity. These molecules are structurally similar to nicotine and act as nicotinic ac...

  • Article
  • Open Access
27 Citations
7,984 Views
15 Pages

In this work, we investigated montmorillonite for adsorption of neonicotinoid insecticides in vortex-assisted dispersive micro-solid phase extraction (VA-d-μ-SPE). High-performance liquid chromatography with photodiode array detection was used for qu...

  • Article
  • Open Access
17 Citations
3,624 Views
11 Pages

3 December 2020

As the main source of nutrients for the important pollinator honeybee, bee pollen is crucial for the health of the honeybee and the agro-ecosystem. In the present study, a new sample preparation procedure has been developed for the determination of n...

  • Article
  • Open Access
8 Citations
2,947 Views
11 Pages

25 April 2022

In this study, a dispersive solid-phase extraction (DSPE) pretreatment procedure using zeolite H-Beta as a sorbent was exploited for the determination of eight neonicotinoids in bottled water and honey products based on ultra-high-performance liquid...

  • Article
  • Open Access
6 Citations
3,486 Views
11 Pages

In-Situ Formation of Modified Nickel–Zinc-Layered Double Hydroxide Followed by HPLC Determination of Neonicotinoid Insecticide Residues

  • Jitlada Vichapong,
  • Rawikan Kachangoon,
  • Rodjana Burakham,
  • Yanawath Santaladchaiyakit and
  • Supalax Srijaranai

22 December 2021

A single-step preconcentration procedure using the in-situ formation of modified nickel–zinc-layered double hydroxides (LDHs) prior to high-performance liquid chromatography (HPLC) is investigated for the determination of neonicotinoid insectic...

  • Article
  • Open Access
11 Citations
3,978 Views
11 Pages

β-Cyclodextrin Assisted Liquid–Liquid Microextraction Based on Solidification of the Floating Organic Droplets Method for Determination of Neonicotinoid Residues

  • Jitlada Vichapong,
  • Khwankaew Moyakao,
  • Rawikan Kachangoon,
  • Rodjana Burakham,
  • Yanawath Santaladchaiyakit and
  • Supalax Srijaranai

31 October 2019

An efficient and environment-friendly microextraction method, namely, β-cyclodextrin assisted liquid–liquid microextraction, based on solidification of the floating organic droplets method coupled with HPLC is investigated for the sensitiv...

  • Article
  • Open Access
28 Citations
4,192 Views
12 Pages

Transgenerational Effects of a Neonicotinoid and a Novel Sulfoximine Insecticide on the Harlequin Ladybird

  • Changchun Dai,
  • Michele Ricupero,
  • Zequn Wang,
  • Nicolas Desneux,
  • Antonio Biondi and
  • Yanhui Lu

28 July 2021

The harlequin ladybird, Harmonia axyridis Pallas (Coleoptera: Coccinellidae), is a generalist predator and an effective biocontrol agent of various insect pests that has been exploited for the control of aphid pests in the greenhouse and field. Howev...

  • Article
  • Open Access
11 Citations
3,292 Views
14 Pages

The Response of the Honey Bee Gut Microbiota to Nosema ceranae Is Modulated by the Probiotic Pediococcus acidilactici and the Neonicotinoid Thiamethoxam

  • Thania Sbaghdi,
  • Julian R. Garneau,
  • Simon Yersin,
  • Frédérique Chaucheyras-Durand,
  • Michel Bocquet,
  • Anne Moné,
  • Hicham El Alaoui,
  • Philippe Bulet,
  • Nicolas Blot and
  • Frédéric Delbac

The honey bee Apis mellifera is exposed to a variety of biotic and abiotic stressors, such as the highly prevalent microsporidian parasite Nosema (Vairimorpha) ceranae and neonicotinoid insecticides. Both can affect honey bee physiology and microbial...

  • Feature Paper
  • Review
  • Open Access
3 Citations
3,575 Views
13 Pages

Recent advances in the microbial degradation of persistent organic pollutants have the potential to mitigate the damage caused by anthropogenic activities that are harmfully impacting agriculture soil ecosystems and human health. In this paper, we su...

  • Article
  • Open Access
31 Citations
4,072 Views
15 Pages

Application of Sludge-Based Activated Carbons for the Effective Adsorption of Neonicotinoid Pesticides

  • Eva Sanz-Santos,
  • Silvia Álvarez-Torrellas,
  • Lucía Ceballos,
  • Marcos Larriba,
  • V. Ismael Águeda and
  • Juan García

30 March 2021

The amount of sludge produced in wastewater treatment plants (WWTPs) has increased over the years, and the methods used to reduce this waste, such as incineration, agricultural use, or disposal in landfills, cause problems of secondary pollution. For...

  • Article
  • Open Access
7 Citations
5,778 Views
42 Pages

Quantification of Neonicotinoid Pesticides in Six Cultivable Fish Species from the River Owena in Nigeria and a Template for Food Safety Assessment

  • Ayodeji O. Adegun,
  • Thompson A. Akinnifesi,
  • Isaac A. Ololade,
  • Rosa Busquets,
  • Peter S. Hooda,
  • Philip C.W. Cheung,
  • Adeniyi K. Aseperi and
  • James Barker

28 August 2020

The Owena River Basin in Nigeria is an area of agricultural importance for the production of cocoa. To optimise crop yield, the cocoa trees require spraying with neonicotinoid insecticides (Imidacloprid, Thiacloprid Acetamiprid and Thiamethoxam). It...

  • Feature Paper
  • Article
  • Open Access
4 Citations
3,904 Views
12 Pages

Neonicotinoid (NN) insecticides derived from natural insecticide nicotine are EU chemical crop protection systemic active substances that are controversial regarding their toxicity and ecotoxicity, especially versus pollinators and birds. Clearly, th...

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