You are currently viewing a new version of our website. To view the old version click .

41 Results Found

  • Article
  • Open Access
Languages2026, 11(1), 9;https://doi.org/10.3390/languages11010009 
(registering DOI)

31 December 2025

This study, based on naturalistic discourse in Mano and on both morphosyntactic and prosodic characteristics, analyses the Mano constructions formed with the marker lɛ́, including the identifying construction, referent introduction, focus,...

  • Feature Paper
  • Article
  • Open Access
7 Citations
4,205 Views
12 Pages

3[Cu2(mand)2(hmt)]–MOF: A Synergetic Effect between Cu(II) and Hexamethylenetetramine in the Henry Reaction

  • Horațiu Szalad,
  • Natalia Candu,
  • Bogdan Cojocaru,
  • Traian D. Păsătoiu,
  • Marius Andruh and
  • Vasile I. Pârvulescu

13 February 2020

∞3[Cu2(mand)2(hmt)]·H2O (where mand is totally deprotonated mandelic acid (racemic mixture) and hmt is hexamethylenetetramine) proved to be a stable metal–organic framework (MOF) structure under thermal activation and catalytic conditions, as confirm...

  • Article
  • Open Access
4 Citations
3,783 Views
16 Pages

Pingelap Island in Pohnpei state is geographically isolated as the nearest island is 70 km away, and such geographical isolation is a challenge for public health due to the limited access to health services. This study aims to reveal the health situa...

  • Article
  • Open Access
2 Citations
1,677 Views
17 Pages

A Comprehensive Assessment of the Economic Performance of an Innovative Solar Thermal System: A Case Study

  • Lisa Gobio-Thomas,
  • Mohamed Darwish,
  • Antonio Rovira,
  • Ruben Abbas,
  • Magdalena Barnetche,
  • Juan Pedro Solano,
  • Albert Torres,
  • Krzysztof Naplocha,
  • Peter Kew and
  • Valentina Stojceska

9 January 2025

An economic assessment of an innovative solar thermal system called Application to Solar Thermal Energy to Processes (ASTEP) was conducted. It considered its three main subsystems: a novel rotary Fresnel SunDial, Thermal Energy Storage (TES) and Cont...

  • Protocol
  • Open Access
3 Citations
3,146 Views
14 Pages

Procedure for Handling and Storage of Onchocerca volvulus Microfilariae Obtained from Skin Snips for Downstream Genetic Work

  • Shannon M. Hedtke,
  • Anusha Kode,
  • Tony O. Ukety,
  • Jöel L. Mande,
  • Germain M. Abhafule,
  • Anuarite A. Raciu,
  • Claude B. Uvon,
  • Stephen R. Jada,
  • An Hotterbeekx and
  • Joseph Nelson Siewe Fodjo
  • + 5 authors

WHO and endemic countries target elimination of transmission of Onchocerca volvulus, the parasite causing onchocerciasis. Population genetic analysis of O. volvulus may provide data to improve the evidence base for decisions on when, where, and for h...

  • Brief Report
  • Open Access
2,749 Views
8 Pages

Lower Limb Paralysis Associated with Chikungunya in Kinshasa, the Democratic Republic of the Congo: Survey Report

  • Mathy Matungala-Pafubel,
  • Junior Bulabula-Penge,
  • Meris Matondo-Kuamfumu,
  • Samy Esala,
  • François Edidi-Atani,
  • Elisabeth Pukuta-Simbu,
  • Paul Tshiminyi-Munkamba,
  • Yannick Tutu Tshia N’kasar,
  • Trésor Katanga and
  • Etienne Ndomba-Mukanya
  • + 10 authors

23 February 2024

Polio-associated paralysis is one of the diseases under national surveillance in the Democratic Republic of the Congo (DRC). Although it has become relatively rare due to control measures, non-polio paralysis cases are still reported and constitute a...

  • Article
  • Open Access
860 Views
18 Pages

Tuberculosis Preventive Treatment in People Living with HIV in Uganda: Facilitators and Barriers for Initiation and Completion

  • Ritah Mande,
  • Pruthu Thekkur,
  • Denis Mudoola,
  • Joseph Nsonga,
  • John Paul Dongo,
  • Simon Muchuro,
  • Stavia Turyahabwe,
  • Henry Luzze,
  • Proscovia Namuwenge and
  • Selma Dar Berger
  • + 4 authors

Tuberculosis preventive treatment (TPT) is a mainstay for reducing the tuberculosis (TB) burden among people living with human immunodeficiency virus (PLHIV). Context-specific challenges hinder TPT uptake and completion among PLHIV. During 2022&ndash...

  • Article
  • Open Access
3 Citations
2,828 Views
33 Pages

Discovering Venom-Derived Drug Candidates Using Differential Gene Expression

  • Joseph D. Romano,
  • Hai Li,
  • Tanya Napolitano,
  • Ronald Realubit,
  • Charles Karan,
  • Mandë Holford and
  • Nicholas P. Tatonetti

9 July 2023

Venoms are a diverse and complex group of natural toxins that have been adapted to treat many types of human disease, but rigorous computational approaches for discovering new therapeutic activities are scarce. We have designed and validated a new pl...

  • Review
  • Open Access
34 Citations
7,926 Views
17 Pages

Power electronics play a fundamental role for electric transportation, renewable energy conversion and many other industrial applications. They have the ability to help achieve high efficiency and performance in power systems. However, traditional in...

  • Article
  • Open Access
5 Citations
5,903 Views
20 Pages

CoRNeA: A Pipeline to Decrypt the Inter-Protein Interfaces from Amino Acid Sequence Information

  • Kriti Chopra,
  • Bhawna Burdak,
  • Kaushal Sharma,
  • Ajit Kembhavi,
  • Shekhar C. Mande and
  • Radha Chauhan

22 June 2020

Decrypting the interface residues of the protein complexes provides insight into the functions of the proteins and, hence, the overall cellular machinery. Computational methods have been devised in the past to predict the interface residues using ami...

  • Feature Paper
  • Review
  • Open Access
41 Citations
13,338 Views
30 Pages

From Mollusks to Medicine: A Venomics Approach for the Discovery and Characterization of Therapeutics from Terebridae Peptide Toxins

  • Aida Verdes,
  • Prachi Anand,
  • Juliette Gorson,
  • Stephen Jannetti,
  • Patrick Kelly,
  • Abba Leffler,
  • Danny Simpson,
  • Girish Ramrattan and
  • Mandë Holford

19 April 2016

Animal venoms comprise a diversity of peptide toxins that manipulate molecular targets such as ion channels and receptors, making venom peptides attractive candidates for the development of therapeutics to benefit human health. However, identifying b...

  • Article
  • Open Access
19 Citations
8,165 Views
21 Pages

Selective Inhibition of Liver Cancer Cells Using Venom Peptide

  • Prachi Anand,
  • Petr Filipenko,
  • Jeannette Huaman,
  • Michael Lyudmer,
  • Marouf Hossain,
  • Carolina Santamaria,
  • Kelly Huang,
  • Olorunseun O. Ogunwobi and
  • Mandë Holford

17 October 2019

Increasingly cancer is being viewed as a channelopathy because the passage of ions via ion channels and transporters mediate the regulation of tumor cell survival, death, and motility. As a result, a potential targeted therapy for cancer is to use ve...

  • Review
  • Open Access
34 Citations
6,573 Views
17 Pages

When Sensor-Cloud Meets Mobile Edge Computing

  • Tian Wang,
  • Yucheng Lu,
  • Zhihan Cao,
  • Lei Shu,
  • Xi Zheng,
  • Anfeng Liu and
  • Mande Xie

3 December 2019

Sensor-clouds are a combination of wireless sensor networks (WSNs) and cloud computing. The emergence of sensor-clouds has greatly enhanced the computing power and storage capacity of traditional WSNs via exploiting the advantages of cloud computing...

  • Article
  • Open Access
847 Views
21 Pages

15 May 2025

This study investigates the impact of China’s construction of high-standard farmland (CHSF) initiatives on grain productivity, focusing on total factor productivity growth of grain (TFPG) from 2000 to 2021. Using a continuous Difference-in-Diff...

  • Article
  • Open Access
1 Citations
2,308 Views
18 Pages

Secondary Metabolites from a New Antibiotic-Producing Endophytic Streptomyces Isolate Inhibited Pathogenic and Multidrug-Resistant Mycobacterium tuberculosis Strains

  • Govinda Raju Vadankula,
  • Arshad Rizvi,
  • Haider Ali,
  • Rakhi Khunjamayum,
  • V. V. Ramprasad Eedara,
  • Vijay Nema,
  • Debananda Singh Ningthoujam,
  • Katragadda Suresh Babu,
  • Prakasham Reddy Shetty and
  • Shekhar C. Mande
  • + 1 author

The long regimen of drug therapy, the emergence of drug-resistance (DR), and infections with non-tuberculous mycobacteria (NTMs) are alarming challenges in controlling tuberculosis (TB), a disease caused by Mycobacterium tuberculosis (M.tb), necessit...

  • Article
  • Open Access
1,163 Views
23 Pages

Degradation of Glyphosate in Water by Electro-Oxidation on Magneli Phase: Application to a Nanofiltration Concentrate

  • Wiyao Maturin Awesso,
  • Ibrahim Tchakala,
  • Sophie Tingry,
  • Geoffroy Lesage,
  • Julie Mendret,
  • Akpénè Amenuvevega Dougna,
  • Eddy Petit,
  • Valérie Bonniol,
  • Mande Seyf-Laye Alfa-Sika and
  • Marc Cretin

28 July 2025

This study evaluates the efficiency of sub-stoichiometric Ti4O7 titanium oxide anodes for the electrochemical degradation of glyphosate, a persistent herbicide classified as a probable carcinogen by the World Health Organization. After optimizing the...

  • Article
  • Open Access
33 Citations
5,548 Views
28 Pages

Adaptive Aggregation Routing to Reduce Delay for Multi-Layer Wireless Sensor Networks

  • Xujing Li,
  • Anfeng Liu,
  • Mande Xie,
  • Neal N. Xiong,
  • Zhiwen Zeng and
  • Zhiping Cai

16 April 2018

The quality of service (QoS) regarding delay, lifetime and reliability is the key to the application of wireless sensor networks (WSNs). Data aggregation is a method to effectively reduce the data transmission volume and improve the lifetime of a net...

  • Article
  • Open Access
48 Citations
5,508 Views
29 Pages

Differentiated Data Aggregation Routing Scheme for Energy Conserving and Delay Sensitive Wireless Sensor Networks

  • Xujing Li,
  • Wei Liu,
  • Mande Xie,
  • Anfeng Liu,
  • Ming Zhao,
  • Neal N. Xiong,
  • Miao Zhao and
  • Wan Dai

19 July 2018

Data aggregation is a widely adopted method to effectively reduce the data transmission volume and improve the lifetime of wireless sensor networks (WSNs). In the data aggregation networks, some parameters directly determine the delay of aggregation....

  • Article
  • Open Access
8 Citations
8,179 Views
12 Pages

Characterization and Recombinant Expression of Terebrid Venom Peptide from Terebra guttata

  • John Moon,
  • Juliette Gorson,
  • Mary Elizabeth Wright,
  • Laurel Yee,
  • Samer Khawaja,
  • Hye Young Shin,
  • Yasmine Karma,
  • Rajeeva Lochan Musunri,
  • Michelle Yun and
  • Mande Holford

3 March 2016

Venom peptides found in terebrid snails expand the toolbox of active compounds that can be applied to investigate cellular physiology and can be further developed as future therapeutics. However, unlike other predatory organisms, such as snakes, tere...

  • Article
  • Open Access
26 Citations
6,972 Views
13 Pages

Isolation and Characterization of a Green-Tissue Promoter from Common Wild Rice (Oryza rufipogon Griff.)

  • Mande Xue,
  • Yan Long,
  • Zhiqiang Zhao,
  • Gege Huang,
  • Ke Huang,
  • Tianbao Zhang,
  • Ying Jiang,
  • Qianhua Yuan and
  • Xinwu Pei

Promoters play a very important role in the initiation and regulation of gene transcription. Green-tissue promoter is of great significance to the development of genetically modified crops. Based on RNA-seq data and RT-PCR expression analysis, this s...

  • Article
  • Open Access
4 Citations
3,776 Views
12 Pages

2 February 2021

Predator-prey interactions are thought to play a driving role in animal evolution, especially for groups that have developed venom as their predatory strategy. However, how the diet of venomous animals influences the composition of venom arsenals rem...

  • Article
  • Open Access
7 Citations
3,480 Views
15 Pages

Dual-Source Bidirectional Quasi-Z-Source Inverter Development for Off-Road Electric Vehicles

  • Daouda Mande,
  • João Pedro F. Trovão,
  • Minh C. Ta and
  • Thang Van Do

In this paper, a battery pack and a supercapacitor bank hybrid energy storage system (HESS) with a new control configuration is proposed for electric vehicles (EVs). A bidirectional quasi-Z-source inverter (Bq-ZSI) and a bidirectional DC-DC converter...

  • Case Report
  • Open Access
377 Views
14 Pages

Socio-Emotional, Behavior and Cognitive Disorders Associated with Exposure to Trace Metals: A Cross-Sectional Pilot Study in School-Age Children in Haut-Katanga Province

  • Eunice Bilonda Mbuyamba,
  • Jean-Paul Ngoy Mande,
  • Paul Musa Obadia,
  • Celestin Banza Lubaba Nkulu,
  • Vincent Haufroid,
  • Benoit Nemery,
  • Claude Mwamba Mulumba,
  • Abdon Mukalay Wa Mukalay,
  • Laurence Ris and
  • Laurent Lefebvre
  • + 1 author

6 November 2025

Introduction: Trace metals can negatively impact biological functions and brain development. Cognitive and neurobehavioral disorders in children are poorly documented in Haut-Katanga Province, an area with significant and multiple exposures to trace...

  • Communication
  • Open Access
19 Citations
8,003 Views
13 Pages

Developing a Dissociative Nanocontainer for Peptide Drug Delivery

  • Patrick Kelly,
  • Prachi Anand,
  • Alexander Uvaydov,
  • Srinivas Chakravartula,
  • Chhime Sherpa,
  • Elena Pires,
  • Alison O’Neil,
  • Trevor Douglas and
  • Mandë Holford

The potency, selectivity, and decreased side effects of bioactive peptides have propelled these agents to the forefront of pharmacological research. Peptides are especially promising for the treatment of neurological disorders and pain. However, deli...

  • Article
  • Open Access
38 Citations
8,959 Views
16 Pages

25 January 2013

High mannose-type oligosaccharides are enzymatically trimmed in the endoplasmic reticulum, resulting in various processing intermediates with exposed glycotopes that are recognized by a series of lectins involved in glycoprotein fate determination in...

  • Article
  • Open Access
1 Citations
4,019 Views
16 Pages

Enhancing Communication in Minimally Verbal Autistic Children: A Study on NAO-Assisted Therapy

  • Marcella Di Cara,
  • Margherita La Fauci,
  • Maria Tresoldi,
  • Maria Rita Caputo,
  • Daniele Borzelli,
  • Roberta Maggio,
  • Caterina Campestre,
  • Antonella Barbera,
  • Adriana Piccolo and
  • Carmela De Domenico
  • + 5 authors

26 May 2025

Background/Objectives: Minimally verbal autistic children face significant communication challenges, often unmet by traditional therapies. Social robots, like NAO, offer predictable, structured interactions that may improve engagement and language sk...

  • Article
  • Open Access
32 Citations
18,798 Views
13 Pages

26 November 2007

Hantzsch condensation of two equivalents of methyl-3-aminocrotonate with (m-and p)-methoxybenzaldehyde afforded the expected products 2,6-dimethyl-3,5-dimethoxycarbonyl-4-(m-methoxyphenyl)-1,4-dihydropyridine and 2,6-dimethyl-3,5-dimethoxycarbonyl-4-...

  • Article
  • Open Access
3 Citations
9,346 Views
12 Pages

16 October 2008

The interaction of guest molecules ranging from pentan-1-ol to octan-1-ol with α-cyclodextrin (α-CD) in water of has been studied calorimetrically at 283.15, 288.15, 293.15, 298.15 and 308.15 K with an isoperibolic titration calorimeter designed in o...

  • Article
  • Open Access
8 Citations
2,340 Views
19 Pages

Estimation of Parameters of Triple Diode Photovoltaic Models Using Hybrid Particle Swarm and Grey Wolf Optimization

  • Hazem Hassan Ellithy,
  • Adel M. Taha,
  • Hany M. Hasanien,
  • Mahmoud A. Attia,
  • Adel El-Shahat and
  • Shady H. E. Abdel Aleem

23 July 2022

The quality of the photovoltaic (PV) cell model impacts many simulation studies for PV systems, such as maximum power point tracking and other assessments. Moreover, due to limited information found in the datasheets of the PV cells, several paramete...

  • Article
  • Open Access
5,406 Views
16 Pages

4 February 2022

The study presents four cases of camouflage treatment of skeletal Class III with occlusal asymmetry in adult patients. Cephalometric analysis was performed using two different reference lines, S-N and FH. The treatment was carried out without the use...

  • Article
  • Open Access
22 Citations
6,712 Views
14 Pages

MHD Flow and Heat Transfer Analysis in the Wire Coating Process Using Elastic-Viscous

  • Zeeshan Khan,
  • Rehan Ali Shah,
  • Saeed Islam,
  • Hamid Jan,
  • Bilal Jan,
  • Haroon-Ur Rasheed and
  • Aurangzeeb Khan

22 January 2017

The most important plastic resins used for wire coating are polyvinyl chloride (PVC), nylon, polysulfone, and low-/high-density polyethylene (LDPE/HDPE). In this article, the coating process is performed using elastic-viscous fluid as a coating mater...

  • Article
  • Open Access
2 Citations
5,973 Views
19 Pages

17 September 2024

The popularity of mobile laser scanning systems as a surveying tool is growing among construction contractors, architects, land surveyors, and urban planners. The user-friendliness and rapid capture of precise and complete data on places and objects...

  • Systematic Review
  • Open Access
8 Citations
3,755 Views
18 Pages

Criterion Validity and Applicability of Motor Screening Instruments in Children Aged 5–6 Years: A Systematic Review

  • Nienke H. van Dokkum,
  • Sijmen A. Reijneveld,
  • Judith Th. B. W. de Best,
  • Marleen Hamoen,
  • Sanne C. M. te Wierike,
  • Arend F. Bos and
  • Marlou L. A. de Kroon

The detection of motor developmental problems, especially developmental coordination disorder, at age 5–6 contributes to early interventions. Here, we summarize evidence on (1) criterion validity of screening instruments for motor developmental...

  • Article
  • Open Access
9 Citations
4,787 Views
22 Pages

8 December 2021

Consumer behaviour in the energy field is playing a more important role in the new approach dominated by the proliferation of renewable energy sources. In this new context, the grid has to balance the intermittent and uncertain renewable energy gener...

  • Article
  • Open Access
19 Citations
6,300 Views
15 Pages

Statistical PM2.5 Prediction in an Urban Area Using Vertical Meteorological Factors

  • Jutapas Saiohai,
  • Surat Bualert,
  • Thunyapat Thongyen,
  • Kittichai Duangmal,
  • Parkpoom Choomanee and
  • Wladyslaw W. Szymanski

19 March 2023

A key concern related to particulate air pollution is the development of an early warning system that can predict local PM2.5 levels and excessive PM2.5 concentration episodes using vertical meteorological factors. Machine learning (ML) algorithms, p...

  • Article
  • Open Access
21 Citations
5,470 Views
14 Pages

Capillary Rise of Nanostructured Microwicks

  • Chang-Ho Choi,
  • Shankar Krishnan,
  • Ward TeGrotenhuis and
  • Chih-Hung Chang

28 March 2018

Capillarity refers to the driving force to propel liquid through small gaps in the absence of external forces, and hence enhanced capillary force has been pursued for various applications. In this study, flower like ZnO nanostructures are successfull...

  • Article
  • Open Access
106 Citations
13,316 Views
26 Pages

25 March 2013

Water bodies are ubiquitous features in Arctic wetlands. Ponds, i.e., waters with a surface area smaller than 104 m2, have been recognized as hotspots of biological activity and greenhouse gas emissions but are not well inventoried. This study aimed...

  • Article
  • Open Access
18 Citations
4,415 Views
25 Pages

7 May 2021

This work capitalises on the morphodynamic study of a scraped artificial dune built on the sandy beach of Porto Garibaldi (Comacchio, Italy) as a barrier to protect the touristic facilities from sea storms during the winter season and contributes to...

  • Article
  • Open Access
2 Citations
3,985 Views
19 Pages

The goal of this paper is to further our understanding of the nature of functional features in Creoles while focusing on how the functional exponent is morphologically realized, assuming a late-insertion-based exoskeletal model in the language mixing...