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The emergence and re-emergence of zoonotic diseases represent one of the most significant public health challenges of the twenty-first century [...]

Decisions about vector-borne zoonotic disease control often have to be made before the evidence is complete. Human surveillance, entomological observations, animal reservoir or sentinel data, environmental indicators, and modelling outputs may provid...

Wastewater treatment plants are important interfaces for the persistence and environmental dissemination of antibiotic-resistant bacteria, yet quantitative culture-based studies comparing treated effluent with paired upstream and downstream receiving...

Historically, mpox was thought to be a geographically constrained ‘disease of poverty,’ leading to decades of neglect by global health actors. Waning population immunity from the cessation of smallpox vaccination and prolonged scientific...

Background/Objectives: Melioidosis is an environmentally acquired infection caused by Burkholderia pseudomallei (B. pseudomallei). Although historically framed as a tropical disease, evidence indicates that recognized risk can extend beyond classical...

Dengue virus (DENV) remains a major global public health challenge, driven by the expanding distribution of Aedes vectors, rapid urbanization, and increasing climate variability. This review aimed to synthesize current evidence on dengue transmission...

Severe malaria remains a global public health challenge, and acute kidney injury (AKI) is a frequent and potentially lethal complication. Variability in diagnostic criteria has limited estimation of the reported burden, particularly in pediatric popu...

Crimean–Congo hemorrhagic fever (CCHF) is a severe tick-borne zoonotic disease associated with high case fatality rates in humans and represents a significant public health threat in endemic areas of Kosovo. However, data on viral circulation i...

Q fever, caused by Coxiella burnetii, is a globally distributed zoonosis that remains substantially underdiagnosed, despite increasing reports of human and animal infections across Europe. Within the Zoonoses Working Group of the Trás-os-Monte...

Ectoparasite-borne infections have become a global public health problem. This study investigated the diversity of fleas and mites associated with wild rodents in the northeastern region of Argentine Patagonia and analyzed the molecular presence of R...

Rat hepatitis E virus (rHEV) is an emerging zoonotic pathogen, increasingly detected in human, animal, and environmental samples globally. Although rHEV shares the same subfamily as human hepatitis E virus (HEV; Paslahepevirus balayani), which is end...

Leptospirosis is a climate-sensitive zoonosis whose transmission is associated with environmental and hydrological conditions, particularly in tropical regions. This ecological time-series study investigated the associations between leptospirosis inc...

Mpox is a zoonotic infectious disease caused by the species Orthopoxvirus monkeypox (MPV), which is becoming an increasing public health concern. While human-to-human transmission of the virus is well established, the role of domestic animals in MPV...

In 2025, the Democratic Republic of the Congo (DRC) experienced its 16th Ebola Virus Disease (EVD) outbreak, centered in the Bulape Health Zone of Kasai Province, amid multiple concurrent epidemics and limited health infrastructure. Genomic sequencin...

Background: Capillaria hepatica is a zoonotic nematode primarily infecting rodents. In humans, it causes hepatic capillariasis, a disease that resembles hepatitis. Rodents act as primary reservoirs and key amplifiers of transmission by ingesting the...

Khettara are traditional underground irrigation systems widely distributed in southern Morocco, many of which are currently abandoned. These semi-subterranean ecosystems may provide suitable microhabitats for phlebotomine sand flies, yet no entomolog...

Porcine cysticercosis, caused by the larval stage of the zoonotic parasite Taenia solium, poses a public health and economic burden in endemic regions. This study explored stakeholder perspectives on porcine cysticercosis control and risk factors in...

Pigs play a key role in the ecology of influenza A viruses (IAVs), particularly in avian influenza (AI)-endemic regions where co-circulation of viruses from different hosts increases reassortment risk. Between September 2023 and August 2024, we surve...

The high genetic diversity and broad host range of betacoronavirus lead to frequent zoonotic outbreaks, posing a severe threat to public health. Therefore, the development of broad-spectrum antiviral agents is critical. Our study evaluated the broad-...

Cryptosporidium spp. is a widely distributed gastrointestinal pathogen in vertebrates, such as the European wild boar. Furthermore, with a fecal–oral pathway, they might spread through tainted food and water or by direct contact. Related to the...

Meat condemnation at slaughterhouses reflects the rate of animal diseases, economic losses, and potential public health risks. In northern Nigeria, however, longitudinal and model-based assessments of condemnation patterns using routine abattoir data...

Variegated squirrel bornavirus 1 (VSBV-1) is a recently identified zoonotic virus associated with fatal encephalitis in humans. A literature search in electronic databases such as PubMed, Web of Science, Scopus, and Google Scholar was performed using...

Brucellosis is a common zoonotic infection in India, caused by a facultative intracellular bacterium, Gram-negative coccobacillus, and frequently presents with nonspecific symptoms. This study aimed to assess serum cytokine levels (IL-6, IL-10, IFN-&...

Bats are recognized reservoirs for a vast array of viral diversity, including members of the Hepadnaviridae family. Within a One Health framework, genomic surveillance of these animals is fundamental to understanding viral diversity and the potential...

The Third Plague Pandemic originated in 19th-century Yunnan, China, yet the confluence of factors that enabled the pandemic strain Yersinia pestis 1.ORI to emerge and spread globally remains unclear. Using a One Health framework, this study investiga...

Pasteurella species are facultatively anaerobic Gram-negative coccobacilli residing in the upper respiratory tract of mammals, fowl and domestic animals including cats and dogs. Localized infections with Pasteurella species are common but invasive in...

Background: The resurgence of Mpox (formerly known as monkeypox) since the 2022 global outbreak has exposed weaknesses in surveillance, diagnosis, and public risk communication systems. Despite increased clinical understanding, limitations in knowled...

Highly pathogenic avian influenza (HPAI) is a transboundary and zoonotic viral disease affecting poultry and wild birds in many countries worldwide. Globally, HPAI outbreaks have led to the death or culling of hundreds of millions of birds over the p...

Chagas disease, caused by Trypanosoma cruzi, is maintained in nature by complex interactions among wild vertebrates and triatomine insect vectors, yet the role of many introduced hosts remains poorly resolved. Here, we assessed natural T. cruzi infec...

Background: Human granulocytic anaplasmosis (HGA) is a tick-borne zoonotic infection caused by Anaplasma phagocytophilum and transmitted by Ixodes species. In temperate regions, HGA is considered seasonal, with most cases occurring during late spring...

Lassa fever remains a major public health threat in West Africa, yet the household and behavioural determinants of prior Lassa virus exposure are not sufficiently understood. This study examined environmental, behavioural, and demographic factors ass...

Crimean–Congo Hemorrhagic Fever (CCHF) disease, caused by the CCHF virus (CCHFV), poses a significant fatality risk whose underlying pathological mechanisms, including the contribution of coagulation factors, imbalances and platelet abnormaliti...

Anthrax, caused by Bacillus anthracis, remains a significant zoonotic disease across the globe disproportionately affecting rural populations reliant on livestock farming. Despite the availability of vaccines for humans and animals, and preventive me...

Tuberculosis (TB) remains a major public health challenge, particularly in sub-Saharan Africa, where the emergence of drug-resistant MTB undermines current control efforts. This study aimed to characterize genetic mutations associated with resistance...

Background: Africa is a continent with diverse climates, landscapes, rainfall patterns, and vegetation types, all of which significantly influence its mammalian fauna, particularly small mammals. Rodents, which are highly diverse across the continent...

Background: With the worldwide resurgence of Mpox in 2022, understanding its regional features is important. This systematic review aimed to provide an overview of the epidemiology, risk factors, clinical features, and outcomes of Mpox in Saudi Arabi...

Brazilian spotted fever (BSF) is a tick-borne acute febrile disease that can be lethal to humans, caused by the bacterium Rickettsia rickettsii. In the State of São Paulo, transmission occurs mainly through two tick species: Amblyomma sculptum...

Background: Human monkeypox is a zoonotic disease caused by the monkeypox virus (MPXV), endemic in Central and West Africa. A significant 2022 outbreak affected 104 countries, driven by increased susceptibility due to the cessation of smallpox vaccin...

Zoonotic diseases represent an important interface between socio-environmental change and public health, yet integrative assessments linking ecological and social determinants remain limited in tropical regions. This study mapped how socio-environmen...

Viral zoonoses represent a critical intersection of global health, ecology, and ethical issues. Pathogens that pass from animals to humans. This review examines the complex landscape of viral zoonoses, including their mechanisms, impact, and mitigati...

Our article presents a holistic analysis aimed at discerning patterns from ancient–modern comparative contexts of malaria. The article’s interdisciplinary and consilient methodology is drawn from a range of disciplines: the humanities and social scie...

Campylobacter spp. are significant zoonotic pathogens, increasingly recognized for their role in the transmission of antimicrobial resistance (AMR) between animals and humans. This study aims to determine the occurrence, antimicrobial resistance prof...

Viral zoonoses or viral pathogens transmitted from animals to humans—constitute a rapidly intensifying global health and economic challenge. They are responsible for an estimated 2.5 billion illnesses and 2.7 million deaths annually, representi...

Influenza A viruses (IAVs) primarily cause respiratory illness but can also induce extrapulmonary effects, which may be aggravated by obesity. This study evaluated the impact of obesity on virus replication, histopathological changes, and cytokine/ch...

The Marburg virus (MARV) is a zoonotic pathogen that causes a high case fatality rate of up to 100% in humans. In response to Marburg virus disease (MVD) outbreaks in the Kagera region, an ecological investigation was initiated to map the population...

Background: Zoonotic fascioliasis and schistosomiasis, caused by trematode parasites transmitted by freshwater snails, are neglected tropical diseases of both medical and veterinary importance. There are critical knowledge gaps regarding the transmis...

Brazil is the first of the 12 priority countries in Latin America with the highest number of cases of American cutaneous leishmaniasis (ACL). This study estimated the prevalence of ACL in Brazil and classified the states according to the different le...

Mpox has re-emerged as a global public health threat, particularly in endemic regions such as Nigeria, where human, animal, and environmental health sectors intersect. To inform surveillance and control strategies, this study assessed the knowledge,...

Brucella canis is a neglected zoonotic pathogen associated with canine reproductive disorders and emerging public health concerns. This study presents the first nationwide systematic review and meta-analysis of Brucella spp. in Portugal, integrated w...

Rickettsia parkeri strain Atlantic rainforest is an emerging pathogen in Brazil, but human infections remain rarely reported. We report the first confirmed case in the municipality of Caraguatatuba on the northern coast of São Paulo State, Bra...