We are pleased to announce that 40 papers in the field of Medicine and Pharmacology have been selected as the 2025 Best Paper Award winners.

Antibiotics:
The Use of Antibiotics and Antimicrobial Resistance in Veterinary Medicine, a Complex Phenomenon: A Narrative Review
Caneschi, A.; Bardhi, A.; Barbarossa, A.; Zaghini, A.
Antibiotics 2023, 12, 487. https://doi.org/10.3390/antibiotics12030487

Antibacterial Activity of Biosynthesized Copper Oxide Nanoparticles (CuONPs) Using Ganoderma sessile
Flores-Rábago, K.M.; Rivera-Mendoza, D.; Vilchis-Nestor, A.R.; Juarez-Moreno, K.; Castro-Longoria, E.
Antibiotics 2023, 12, 1251. https://doi.org/10.3390/antibiotics12081251

Cancers:
Characteristics and Clinical Outcomes of Patients with Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma Receiving Ibrutinib for ≥5 Years in the RESONATE-2 Study
Woyach, J.A.; Barr, P.M.; Kipps, T.J.; Barrientos, J.C.; Ahn, I.E.; Ghia, P.; Girardi, V.; Hsu, E.; Jermain, M.; Burger, J.A.
Cancers 2023, 15, 507. https://doi.org/10.3390/cancers15020507

Mechanisms of ADC Toxicity and Strategies to Increase ADC Tolerability
Nguyen, T.D.; Bordeau, B.M.; Balthasar, J.P.
Cancers 2023, 15, 713. https://doi.org/10.3390/cancers15030713

Circulating Chromosome Conformation Signatures Significantly Enhance PSA Positive Predicting Value and Overall Accuracy for Prostate Cancer Detection
Pchejetski, D.; Hunter, E.; Dezfouli, M.; Salter, M.; Powell, R.; Green, J.; Naithani, T.; Koutsothanasi, C.; Alshaker, H.; Jaipuria, J.; et al.
Cancers 2023, 15, 821. https://doi.org/10.3390/cancers15030821

What Is Known about Breast Cancer in Young Women?
Zhu, J.W.; Charkhchi, P.; Adekunte, S.; Akbari, M.R.
Cancers 2023, 15, 1917. https://doi.org/10.3390/cancers15061917

Clinics and Practice:
Teaching Deprescribing and Combating Polypharmacy in the Pharmacy Curriculum: Educational Recommendations from Thematic Analysis of Focus Groups
Scott, D.; Cernasev, A.; Barenie, R.E.; Springer, S.P.; Axon, D.R.
Clin. Pract. 2023, 13, 442-453. https://doi.org/10.3390/clinpract13020040

Clinical Research in Prehospital Care: Current and Future Challenges
Cimino, J.; Braun, C.
Clin. Pract. 2023, 13, 1266-1285. https://doi.org/10.3390/clinpract13050114 

COVID:
Onset of Mental Disorders Following Hospitalization for COVID-19: A 6-Month Follow-Up Study
Chamorro-Delmo, J.; Portillo De-Antonio, P.; Porras-Segovia, A.; de León-Martínez, S.; Figuero Oltra, M.; del Pozo-Herce, P.; Sánchez-Escribano Martínez, A.; Abejón Pérez, I.; Vera-Varela, C.; Postolache, T.T.; et al.
COVID 2023, 3, 218-225. https://doi.org/10.3390/covid3020016

A Comprehensive Analysis of Structural and Functional Changes Induced by SARS-CoV-2 Spike Protein Mutations
Mushebenge, A.G.-A.; Ugbaja, S.C.; Mbatha, N.A.; Khan, R.B.; Kumalo, H.M.
COVID 2023, 3, 1454-1472. https://doi.org/10.3390/covid3090100

Dentistry Journal:
Retrospective Longitudinal Study on Changes in Atmospheric Pressure as a Predisposing Factor for Odontogenic Abscess Formation
Tarle, M.; Zubović, A.; Kos, B.; Raguž, M.; Lukšić, I.
Dent. J. 2023, 11, 42. https://doi.org/10.3390/dj11020042 

Exploring the Role of IL-17A in Oral Dysbiosis-Associated Periodontitis and Its Correlation with Systemic Inflammatory Disease
Irie, K.; Azuma, T.; Tomofuji, T.; Yamamoto, T.
Dent. J. 2023, 11, 194. https://doi.org/10.3390/dj11080194 

Diagnostics:
Determining HER2 Status by Artificial Intelligence: An Investigation of Primary, Metastatic, and HER2 Low Breast Tumors
Palm, C.; Connolly, C.E.; Masser, R.; Padberg Sgier, B.; Karamitopoulou, E.; Simon, Q.; Bode, B.; Tinguely, M.
Diagnostics 2023, 13, 168. https://doi.org/10.3390/diagnostics13010168

The Bidirectional Relationship between Periodontal Disease and Diabetes Mellitus—A Review
Păunică, I.; Giurgiu, M.; Dumitriu, A.S.; Păunică, S.; Pantea Stoian, A.M.; Martu, M.-A.; Serafinceanu, C.
Diagnostics 2023, 13, 681. https://doi.org/10.3390/diagnostics13040681

Skin Cancer Detection Using Deep Learning—A Review
Naqvi, M.; Gilani, S.Q.; Syed, T.; Marques, O.; Kim, H.-C.
Diagnostics 2023, 13, 1911. https://doi.org/10.3390/diagnostics13111911

Generalist Vision Foundation Models for Medical Imaging: A Case Study of Segment Anything Model on Zero-Shot Medical Segmentation
Shi, P.; Qiu, J.; Abaxi, S.M.D.; Wei, H.; Lo, F.P.-W.; Yuan, W.
Diagnostics 2023, 13, 1947. https://doi.org/10.3390/diagnostics13111947

Journal of Clinical Medicine:
Prevalence of Overweight and Obesity in France: The 2020 Obepi-Roche Study by the “Ligue Contre l’Obésité”
Fontbonne, A.; Currie, A.; Tounian, P.; Picot, M.-C.; Foulatier, O.; Nedelcu, M.; Nocca, D.
J. Clin. Med. 2023, 12, 925. https://doi.org/10.3390/jcm12030925 

Past, Present and (Foreseeable) Future of Biological Anti-TNF Alpha Therapy
Leone, G.M.; Mangano, K.; Petralia, M.C.; Nicoletti, F.; Fagone, P.
J. Clin. Med. 2023, 12, 1630. https://doi.org/10.3390/jcm12041630 

Stage IV Colorectal Cancer Management and Treatment
Hernandez Dominguez, O.; Yilmaz, S.; Steele, S.R.
J. Clin. Med. 2023, 12, 2072. https://doi.org/10.3390/jcm12052072

Irritable Bowel Syndrome and the Gut Microbiome: A Comprehensive Review
Shaikh, S.D.; Sun, N.; Canakis, A.; Park, W.Y.; Weber, H.C.
J. Clin. Med. 2023, 12, 2558. https://doi.org/10.3390/jcm12072558

Using Generative Artificial Intelligence Tools in Cosmetic Surgery: A Study on Rhinoplasty, Facelifts, and Blepharoplasty Procedures
Lim, B.; Seth, I.; Kah, S.; Sofiadellis, F.; Ross, R.J.; Rozen, W.M.; Cuomo, R.
J. Clin. Med. 2023, 12, 6524. https://doi.org/10.3390/jcm12206524

Journal of Personalized Medicine:
Predicting the Onset of Diabetes with Machine Learning Methods
Chou, C.-Y.; Hsu, D.-Y.; Chou, C.-H.
J. Pers. Med. 2023, 13, 406. https://doi.org/10.3390/jpm13030406

Challenging ChatGPT 3.5 in Senology—An Assessment of Concordance with Breast Cancer Tumor Board Decision Making
Griewing, S.; Gremke, N.; Wagner, U.; Lingenfelder, M.; Kuhn, S.; Boekhoff, J.
J. Pers. Med. 2023, 13, 1502. https://doi.org/10.3390/jpm13101502

Medicina:
Robotic-Assisted Total Knee Arthroplasty Utilizing NAVIO, CORI Imageless Systems and Manual TKA Accurately Restore Femoral Rotational Alignment and Yield Satisfactory Clinical Outcomes: A Randomized Controlled Trial
Adamska, O.; Modzelewski, K.; Szymczak, J.; Świderek, J.; Maciąg, B.; Czuchaj, P.; Poniatowska, M.; Wnuk, A.
Medicina 2023, 59, 236. https://doi.org/10.3390/medicina59020236

The RANK–RANKL–OPG System: A Multifaceted Regulator of Homeostasis, Immunity, and Cancer
De Leon-Oliva, D.; Barrena-Blázquez, S.; Jiménez-Álvarez, L.; Fraile-Martinez, O.; García-Montero, C.; López-González, L.; Torres-Carranza, D.; García-Puente, L.M.; Carranza, S.T.; Álvarez-Mon, M.Á.; et al.
Medicina 2023, 59, 1752. https://doi.org/10.3390/medicina59101752

Pharmaceuticals:
Cannabidiol and Minor Phytocannabinoids: A Preliminary Study to Assess Their Anti-Melanoma, Anti-Melanogenic, and Anti-Tyrosinase Properties
Gaweł-Bęben, K.; Czech, K.; Luca, S.V.
Pharmaceuticals 2023, 16, 648. https://doi.org/10.3390/ph16050648

Morin Sensitizes MDA-MB-231 Triple-Negative Breast Cancer Cells to Doxorubicin Cytotoxicity by Suppressing FOXM1 and Attenuating EGFR/STAT3 Signaling Pathways
Maharjan, S.; Lee, M.-G.; Kim, S.-Y.; Lee, K.-S.; Nam, K.-S.
Pharmaceuticals 2023, 16, 672. https://doi.org/10.3390/ph16050672

Computer-Aided Drug Design and Drug Discovery: A Prospective Analysis
Niazi, S.K.; Mariam, Z.
Pharmaceuticals 2024, 17, 22. https://doi.org/10.3390/ph17010022 

Pharmaceutics:
Biodistribution of Intratracheal, Intranasal, and Intravenous Injections of Human Mesenchymal Stromal Cell-Derived Extracellular Vesicles in a Mouse Model for Drug Delivery Studies
Tolomeo, A.M.; Zuccolotto, G.; Malvicini, R.; De Lazzari, G.; Penna, A.; Franco, C.; Caicci, F.; Magarotto, F.; Quarta, S.; Pozzobon, M.; et al.
Pharmaceutics 2023, 15, 548. https://doi.org/10.3390/pharmaceutics15020548

Polymeric Micellar Systems—A Special Emphasis on “Smart” Drug Delivery
Negut, I.; Bita, B.
Pharmaceutics 2023, 15, 976. https://doi.org/10.3390/pharmaceutics15030976

Pharmacy:
Subjective Perceptions of Occupational Fatigue in Community Pharmacists
Watterson, T.L.; Chui, M.A.
Pharmacy 2023, 11, 84. https://doi.org/10.3390/pharmacy11030084

Personalizing Personalized Medicine: The Confluence of Pharmacogenomics, a Person’s Medication Experience and Ethics
Stratton, T.P.; Olson, A.W.
Pharmacy 2023, 11, 101. https://doi.org/10.3390/pharmacy11030101 

Sports:
The eSports Medicine: Pre-Participation Screening and Injuries Management—An Update
Rossoni, A.; Vecchiato, M.; Brugin, E.; Tranchita, E.; Adami, P.E.; Bartesaghi, M.; Cavarretta, E.; Palermi, S.
Sports 2023, 11, 34. https://doi.org/10.3390/sports11020034

Fatigue-Induced Neuromuscular Performance Changes in Professional Male Volleyball Players
Cabarkapa, D.V.; Cabarkapa, D.; Whiting, S.M.; Fry, A.C.
Sports 2023, 11, 120. https://doi.org/10.3390/sports11060120

Tomography:
Feasibility of [¹⁸F]FSPG PET for Early Response Assessment to Combined Blockade of EGFR and Glutamine Metabolism in Wild-Type KRAS Colorectal Cancer
Bae, S.-W.; Wang, J.; Georgiou, D.K.; Wen, X.; Cohen, A.S.; Geng, L.; Tantawy, M.N.; Manning, H.C.
Tomography 2023, 9, 497-508. https://doi.org/10.3390/tomography9020041

Computed Tomography Urography: State of the Art and Beyond
Cellina, M.; Cè, M.; Rossini, N.; Cacioppa, L.M.; Ascenti, V.; Carrafiello, G.; Floridi, C.
Tomography 2023, 9, 909-930. https://doi.org/10.3390/tomography9030075

Vaccines:
An RNA-Based Vaccine Platform for Use against Mycobacterium tuberculosis
Larsen, S.E.; Erasmus, J.H.; Reese, V.A.; Pecor, T.; Archer, J.; Kandahar, A.; Hsu, F.-C.; Nicholes, K.; Reed, S.G.; Baldwin, S.L.; et al.
Vaccines 2023, 11, 130. https://doi.org/10.3390/vaccines11010130

A Systematic Review and Meta-Analysis on the Real-World Effectiveness of COVID-19 Vaccines against Infection, Symptomatic and Severe COVID-19 Disease Caused by the Omicron Variant (B.1.1.529)
Mohammed, H.; Pham-Tran, D.D.; Yeoh, Z.Y.M.; Wang, B.; McMillan, M.; Andraweera, P.H.; Marshall, H.S.
Vaccines 2023, 11, 224. https://doi.org/10.3390/vaccines11020224

The Potential Role of Vaccines in Preventing Antimicrobial Resistance (AMR): An Update and Future Perspectives
Costanzo, V.; Roviello, G.N.
Vaccines 2023, 11, 333. https://doi.org/10.3390/vaccines11020333

Factors Influencing Antibody Response to SARS-CoV-2 Vaccination
Kodde, C.; Tafelski, S.; Balamitsa, E.; Nachtigall, I.; Bonsignore, M.
Vaccines 2023, 11, 451. https://doi.org/10.3390/vaccines11020451