Pathogens, Volume 9, Issue 4 (April 2020) – 76 articles
Cover Story (view full-size image): For clinical epidemiology specialists, connecting the genetic diversity of Echinococcus multilocularis (Em) to sources of infection or particular sites has become somewhat of a holy grail. The long incubation period makes it difficult to trace the infection history of alveolar echinococcosis (AE). Genetic variability in Em and various levels of pathogenicity may explain the various parasitic manifestations in human patients, by different genotypes detected. In this study, we investigated through the microsatellite marker EmsB a panel of 63 patients diagnosed with AE, originating from different European countries. Nine EmsB profiles were identified among patients. This study sheds light on possible contamination pathways in humans, as proximity contamination in some cases, and the dominant contamination profiles in Europe, particularly for extrahepatic lesions. View this paper
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