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Diagnostics, Volume 15, Issue 22

2025 November-2 - 117 articles

Cover Story: This study analyzes the prevalence and clinical relevance of incidental findings from 683 chest CT scans performed for suspected COVID-19 over nearly two years. Using the COVID-19 Pneumonia Imaging Classification and a structured relevance scale, we evaluated how these findings were identified, categorized, and clinically managed. Incidental findings occurred in 94 patients (13.8%), with women affected more frequently. Although most findings were of limited clinical significance, several required further diagnostics and work up. This study highlights the need for consistent follow-up and standardized management pathways to ensure that clinically significant incidental findings are appropriately addressed. View this paper
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Articles (117)

  • Case Report
  • Open Access
570 Views
10 Pages

Laser Confocal Microscopy May Be a Useful Tool in Neuropathological Intraoperative Examination

  • Deborah Dardano,
  • Anna Bilotta,
  • Gianmarco Gallucci,
  • Carlo Gentile,
  • Giuseppe Riganati,
  • Antonio Veraldi,
  • Domenico Policicchio,
  • Maria Teresa Nevolo,
  • Alberto V. Filardo and
  • Giuseppe Donato
  • + 1 author

20 November 2025

Background and Clinical Significance: The paper investigates the use of the Histolog® Scanner, a confocal microscopy–based device, as a potential tool for intraoperative neuropathological diagnosis of brain tumors. Traditional intraoperativ...

  • Article
  • Open Access
907 Views
19 Pages

Prevalence and Clinical Associations of Malnutrition and Sarcopenia Risk in Gastroenterology Inpatients: A Multicenter Cross-Sectional Study in Turkey

  • Göksel Bengi,
  • Süleyman Dolu,
  • Yavuz Özden,
  • Nevin Oruç,
  • Mukaddes Tozlu,
  • Gözde Derviş Hakim,
  • Genco Gençdal,
  • Ali Rıza Çalışkan,
  • Müge Ustaoğlu and
  • Hale Akpınar
  • + 35 authors

20 November 2025

Background/Objectives: This study aimed to determine the prevalence of malnutrition and sarcopenia risk among patients hospitalized in gastroenterology clinics across different geographical regions of Turkey, to identify their risk factors, and to ev...

  • Article
  • Open Access
1,118 Views
14 Pages

Depression, Functional Dependence, and Oral Health: Evidence from a Clinical Study of Older Spanish Adults

  • Carmen Esperanza Abregú-Flores,
  • Pedro Luis Ruiz-Sáenz,
  • María Andrés-Veiga,
  • Fernando Fernández-Cáliz,
  • Cristina Meniz-García and
  • Natalia Martínez-Rodríguez

20 November 2025

Background: Depression is a prevalent mental health condition among older adults and may be linked to multiple systemic and functional factors. Emerging evidence suggests a bidirectional relationship between depressive symptoms and poor oral health,...

  • Article
  • Open Access
997 Views
11 Pages

20 November 2025

Objective: To evaluate changes in maxillary incisor inclination before and after orthodontic treatment in adults with different vertical facial patterns (normodivergent, hypodivergent, hyperdivergent) and to assess the relationship of incisor inclina...

  • Review
  • Open Access
2 Citations
1,739 Views
19 Pages

Active Matrixmetalloproteinase-8 in Periodontal Diagnosis: A Scoping Review

  • Lata Goyal,
  • Mehak Gupta,
  • Shubham Sareen,
  • Nur Rahman Ahmad Seno Aji,
  • Vaibhav Sahni,
  • Julie Toby Thomas,
  • Tommi Pätilä,
  • Miika Penttala,
  • Pirjo Pärnänen and
  • Pietro Leone
  • + 3 authors

20 November 2025

Background/Objectives: Periodontitis is a chronic inflammatory disease initiated by dysbiotic biofilms and driven by host immune dysregulation, leading to connective tissue destruction and alveolar bone loss. Its early diagnosis is closely linked to...

  • Article
  • Open Access
659 Views
13 Pages

Clinical and CT Features of HIV-Negative and HIV-Positive Patients with Abdominal Tuberculous Lymphadenopathy

  • Xiao-Ling Zhu,
  • Sheng-Xiu Lv,
  • Li Wen,
  • Ran Li,
  • Xue-Yan Liu and
  • Guang-Xian Wang

20 November 2025

Background: The diagnosis of abdominal tuberculous lymphadenopathy (ATBL) remains challenging in clinical practice. Patients with ATBL and HIV infection may have atypical clinical and computed tomography (CT) features. The aim of this study was to in...

  • Article
  • Open Access
1 Citations
906 Views
14 Pages

Characterization of Peripheral Retinal Degenerations and Rhegmatogenous Lesions Using Ultra-Widefield Swept Source OCT Integrated with a Novel Scanning Laser Ophthalmoscope

  • Daniela Bacherini,
  • Clara Rizzo,
  • Giulio Vicini,
  • Diego Luciani,
  • Lorenzo Vannozzi,
  • Gianni Virgili,
  • Fabrizio Giansanti and
  • Cristina Nicolosi

20 November 2025

Background/Objectives: The purpose of this study was to evaluate the implementation of ultra-widefield swept-source optical coherence tomography (SS-OCT) in characterizing peripheral retinal degenerations and rhegmatogenous lesions, and to assess its...

  • Article
  • Open Access
660 Views
17 Pages

Personalized Low-Invasive Approach to Chronic Endometritis Evaluation in Premenopausal Women: Machine Learning-Based Modeling

  • Kseniia D. Ievleva,
  • Alina V. Atalyan,
  • Timur G. Baintuev,
  • Iana G. Nadeliaeva,
  • Ludmila M. Lazareva,
  • Eldar M. Sharifulin,
  • Margarita R. Akhmedzyanova,
  • Leonid F. Sholokhov,
  • Irina N. Danusevich and
  • Larisa V. Suturina

19 November 2025

Background/Objectives: Chronic endometritis (CE) is a well-known risk factor for recurrent implantation failure. However, the traditional approach to CE diagnosis has several drawbacks. On the other hand, there is a lot of evidence that some clinical...

  • Article
  • Open Access
543 Views
14 Pages

Performance Comparison of In-House and Commercial Biosynex Helmints AMPLIQUICK® Real-Time PCR Assays for the Diagnosis of Schistosoma mansoni and Strongyloides stercoralis in Stool Samples

  • Davide Treggiari,
  • Francesca Tamarozzi,
  • Fabio Formenti,
  • Salvatore Scarso,
  • Barbara Pajola,
  • Lavinia Nicolini,
  • Cristina Mazzi and
  • Francesca Perandin

19 November 2025

Background/Objectives: The timely diagnosis of schistosomiasis and strongyloidiasis is important because of their potentially severe, even lethal, consequences. European diagnostic laboratories must comply with the European In Vitro Diagnostic (IVD)...

  • Review
  • Open Access
2 Citations
2,188 Views
21 Pages

The Interleukin Network in Sepsis: From Cytokine Storm to Clinical Applications

  • Marcello Candelli,
  • Marta Sacco Fernandez,
  • Gloria Rozzi,
  • Giorgio Sodero,
  • Andrea Piccioni,
  • Giulia Pignataro,
  • Donato Rigante and
  • Francesco Franceschi

19 November 2025

Background and Objectives: Despite major advances in medical science and critical care, sepsis remains a leading cause of morbidity and mortality worldwide: it arises from dysregulated host response to infections and may culminate in organ dysfunctio...

  • Article
  • Open Access
931 Views
20 Pages

Diagnostic Value of Opportunistic CT-Based Bone Density Assessment in Patients with and Without Sacral Insufficiency Fractures

  • Julian Ramin Andresen,
  • Guido Schröder,
  • Thomas Haider,
  • Hans-Christof Schober and
  • Reimer Andresen

19 November 2025

Background/Objectives: This retrospective observational cohort examined whether opportunistic CT-derived Hounsfield units (HU) of the lumbar spine and proximal femur together with serum 25-OH-vitamin D can predict sacral insufficiency fractures (SIF)...

  • Article
  • Open Access
1,160 Views
14 Pages

New Classification of Midpalatine Suture Maturation Using Cone Beam Computed Tomographic Study

  • Cristalle Soman,
  • Reem Khaled Alshammari,
  • Nawal Mohammad AlMutairi,
  • Lolwah Mohammad Alenezi,
  • Rayan Alaadwany,
  • Mohammad Abdul Baseer,
  • Fahdah Aldahash,
  • Malak AlOsaimi,
  • Sara Tarek Ahmed and
  • Yasmine Tarek Ahmed
  • + 1 author

19 November 2025

Background/Objectives: Assessment of the midpalatine suture is vital for making clinical decisions regarding the correction of transverse growth discrepancies of the maxilla. Several studies have used Cone Beam Computed Tomography (CBCT) to evaluate...

  • Article
  • Open Access
654 Views
17 Pages

19 November 2025

Background/Objectives: Accurate segmentation of skin lesions is essential for early skin cancer detection. However, traditional CNNs are limited in modeling long-range dependencies, leading to poor performance on lesions with complex shapes. Methods:...

  • Article
  • Open Access
1,047 Views
13 Pages

19 November 2025

Background: Accurate sex estimation is crucial in forensic identification when DNA analysis is impractical or remains are fragmented. Traditional anthropometric approaches often rely on single bone measurements and yield moderate levels of accuracy....

  • Article
  • Open Access
747 Views
13 Pages

Prevalence of Diabetes Among First-Time Ophthalmology Patients at a Nonprofit Hospital in Mexico

  • Valeria Sánchez-Huerta,
  • Mary Lady González Suriel,
  • Héctor Randolph,
  • María José Barragán Álvarez and
  • Benjamin Aleman-Castilla

19 November 2025

Background/Objectives: Diabetes is Mexico’s second-leading cause of death, primary cause of disability, and diabetic retinopathy (DR) associated with this disease is the leading cause of vision loss among the working population. Limited healthc...

  • Review
  • Open Access
1 Citations
952 Views
16 Pages

Cardiovascular Disease in Pregnancy: When Two Hearts Beat as One

  • Chiara Tognola,
  • Filippo Brucato,
  • Alessandro Maloberti,
  • Marisa Varrenti,
  • Alberto Preda,
  • Patrizio Mazzone,
  • Cristina Giannattasio and
  • Fabrizio Guarracini

19 November 2025

Background: Cardiovascular disease (CVD) in pregnancy is a major cause of maternal morbidity and mortality, accounting for nearly one-third of pregnancy-related deaths worldwide. Physiological adaptations—expanded plasma volume, increased cardi...

  • Article
  • Open Access
2,095 Views
17 Pages

Normative Data for the Montreal Cognitive Assessment (MoCA) in Mexican Adults: A Regression-Based Approach

  • Lorena Parra-Rodríguez,
  • Juan Silva-Pereyra,
  • Sergio Sánchez-García,
  • Carmen García-Peña,
  • Juan Francisco Flores-Vázquez and
  • Paloma Roa-Rojas

19 November 2025

Background/Objectives: The Montreal Cognitive Assessment (MoCA) is a widely used cognitive screening tool designed to detect cognitive impairment. However, evidence indicates that the original cut-off score of 26 and the one-point correction for low...

  • Editorial
  • Open Access
593 Views
11 Pages

19 November 2025

The drivers of healthcare inequalities, often interlinked, include socioeconomic status, geographic barriers, gender, age, and ethnicity [...]

  • Review
  • Open Access
1 Citations
976 Views
15 Pages

Artificial Intelligence for the Diagnosis and Management of Patellofemoral Instability: A Comprehensive Review

  • Michele Mercurio,
  • Federica Denami,
  • Andrea Vescio,
  • Filippo Familiari,
  • Umile Giuseppe Longo,
  • Olimpio Galasso,
  • Giorgio Gasparini and
  • David H. Dejour

18 November 2025

Patellofemoral instability (PFI) is a multifactorial orthopedic condition affecting predominantly young and active individuals. Accurate diagnosis and personalized treatment planning remain challenging due to the complex interplay of anatomical and b...

  • Article
  • Open Access
1,350 Views
19 Pages

Development and Evaluation of a Smartphone App-Based Rapid 25-Hydroxy Vitamin D Test

  • SoYeong Han,
  • Seung Hyun Kim,
  • MyungJin Kim,
  • NaMi Park,
  • Junnan Gu,
  • Sun Jong Kim,
  • Suk Yong Lee and
  • Jeongku Seo

18 November 2025

Objectives: The purpose of this study is to develop and verify a sandwich-type lateral flow immunoassay (LFA) integrated with a smartphone, enabling semi-quantitative 25-hydroxyvitamin D [25(OH)D] measurement including automated image analysis functi...

  • Article
  • Open Access
539 Views
23 Pages

Oxidative Stress Markers Associated with Gingival Inflammatory Status in Children with Leukemia

  • Alina Adumitroaie,
  • Larisa Ghemiș,
  • Maria-Alexandra Mârțu,
  • Liliana Georgeta Foia,
  • Catalina Iulia Saveanu,
  • Delia Lidia Salaru,
  • Alina Andronovici,
  • Carmen Delianu and
  • Vasilica Toma

18 November 2025

Background/Objectives: This study aimed to investigate specific biomarkers of oxidative stress within gingival crevicular fluid (GCF) and plasma obtained from children with leukemia compared to healthy subjects, in relation to the oral hygiene status...

  • Article
  • Open Access
1 Citations
903 Views
20 Pages

Delta-Radiomics Biomarker in Colorectal Cancer Liver Metastases Treated with Cetuximab Plus Avelumab (CAVE Trial)

  • Valerio Nardone,
  • Vittorio Patanè,
  • Luca Marinelli,
  • Luca D’Ambrosio,
  • Sara Del Tufo,
  • Marco De Chiara,
  • Maria Chiara Brunese,
  • Dino Rubini,
  • Roberta Grassi and
  • Alfonso Reginelli
  • + 5 authors

18 November 2025

Background: Radiomics enables the extraction of quantitative imaging biomarkers that can non-invasively capture tumor biology and treatment response. Delta-radiomics, by assessing temporal changes in radiomic features, may improve reproducibility and...

  • Article
  • Open Access
1,209 Views
20 Pages

Pilates-Based Exercise and Its Impact on Nutritional Status and Health-Related Quality of Life in Older Adults with Type 2 Diabetes: A Randomized Controlled Trial

  • Beatriz Ruiz-Ariza,
  • Agustín Aibar-Almazán,
  • Fidel Hita-Contreras,
  • Yolanda Castellote-Caballero and
  • María del Carmen Carcelén-Fraile

18 November 2025

Background/Objectives: Type 2 diabetes mellitus (T2DM) is a prevalent chronic disease frequently associated with impaired nutritional status and reduced health-related quality of life (HRQoL), especially in older adults. Alongside pharmacological tre...

  • Article
  • Open Access
1 Citations
726 Views
12 Pages

Deep Learning Performance in Analyzing Nailfold Videocapillaroscopy Images in Systemic Sclerosis

  • Müçteba Enes Yayla,
  • Ayhan Aydın,
  • Mahmut Kılıçaslan,
  • Mürüvvet Kalkan,
  • Mehmet Serdar Güzel,
  • Aida Shikhaliyeva,
  • Serdar Sezer,
  • Emine Uslu,
  • Aşkın Ateş and
  • Tahsin Murat Turgay

18 November 2025

Background/Objectives: The aim of this study was to classify nailfold videocapillaroscopy (NVC) images obtained from patients with systemic sclerosis (SSc) and healthy individuals using deep learning methods. Methods: Between January and June 2025, 1...

  • Review
  • Open Access
1 Citations
2,161 Views
38 Pages

Anatomy, Imaging, and Clinical Significance of the Cervicothoracic (Stellate) Ganglion

  • Mugurel Constantin Rusu,
  • Ionuţ Mădălin Munteanu,
  • Alexandra Diana Vrapciu,
  • Adelina Maria Jianu,
  • Sorin Hostiuc,
  • Răzvan Costin Tudose and
  • Andrei Gheorghe Marius Motoc

17 November 2025

Background/Objectives: The stellate ganglion (SG), formed by the fusion of the inferior cervical and first thoracic sympathetic ganglia in approximately 80% of individuals, plays crucial roles in cardiac innervation, pain management, and autonomic re...

  • Article
  • Open Access
1 Citations
729 Views
18 Pages

Reduced Serum sRAGE Levels Identify COPD and Reflect Disease Severity: Findings from a Cross-Sectional Study in India

  • Venkateshkumar Chandanna Seri,
  • Mohammed Kaleem Ullah,
  • Jayaraj Biligere Siddaiah,
  • Sindaghatta Krishnarao Chaya,
  • Komarla Sundararaja Lokesh,
  • Suhail Azam Khan,
  • Aishwarya R. Aladakatti,
  • Shamnaz Shahul,
  • Vivek Vasanthan and
  • Padukudru Anand Mahesh
  • + 7 authors

17 November 2025

Background: Chronic Obstructive Pulmonary Disease (COPD) remains a leading cause of morbidity and mortality worldwide, particularly in low- and middle-income countries (LMICs), where both tobacco and biomass smoke exposure are major risk factors. Whi...

  • Article
  • Open Access
619 Views
13 Pages

Association Between Osseous Shoulder Morphology and Pathoanatomical Characteristics of Calcific Deposits in Rotator Cuff Calcific Tendinitis

  • Andro Matković,
  • Mia Grgić,
  • Ines Trkulja,
  • Marija Ivković,
  • Thomas Ferenc,
  • Nikolina Jurjević,
  • Božidar Šebečić and
  • Vinko Vidjak

17 November 2025

Background/Objectives: Rotator cuff calcific tendinitis (RCCT) is a common cause of shoulder pain. The role of acromial morphology in RCCT pathogenesis remains unclear. This study aimed to evaluate association between acromial morphological parameter...

  • Article
  • Open Access
936 Views
15 Pages

Associations Between Th17 Cell Markers (IL-23R, CCR6, and IL-17) and Clinical Profiles in Sjögren’s Disease

  • Erika Fabiola López-Villalobos,
  • Jose Antonio Garcia-Espinoza,
  • Mariel García-Chagollán,
  • Jefte Felipe Uribe-Martínez,
  • Sergio Cerpa-Cruz,
  • José Francisco Muñoz-Valle,
  • Claudia Azucena Palafox-Sánchez and
  • Edith Oregon-Romero

17 November 2025

Background/objectives: Sjögren’s disease (SjD) is an autoimmune disorder characterized by lymphocytic infiltration and inflammation leading to exocrine gland dysfunction. Th17 cells play a central role in autoimmune pathology and are defin...

  • Article
  • Open Access
1,348 Views
14 Pages

Autoimmune Metaplastic Atrophic Gastritis Reporting: Are Pathologists and Endoscopists on the Same Page?

  • Nicole Vienneau,
  • Hwajeong Lee,
  • Xulang Zhang,
  • Eundong Park,
  • Madeline Cleary,
  • Jing Zhou,
  • Shunsa Tarar,
  • Meng Liu and
  • Micheal Tadros

17 November 2025

Background/Objectives: Autoimmune metaplastic atrophic gastritis (AMAG) is a chronic, autoimmune-mediated condition associated with increased risk of malignancy and nutritional deficiencies, yet diagnostic and follow-up processes remain inconsistent...

  • Article
  • Open Access
1,029 Views
14 Pages

Quantitative Bone SPECT/CT in Diabetic Foot Osteomyelitis: Diagnostic Performance Within-Patient Lesion–Contralateral Separation and Associations with Inflammatory Burden

  • Hulya Peker Yalcin,
  • Pınar Akkus Gunduz,
  • Mehmet Samsum,
  • Emel Colak Samsum,
  • Aysenur Erol,
  • Umut Mert Turan,
  • Gulsah Gedikli Turgut,
  • Aysun Yalci,
  • Nihal Yesildag and
  • Nesibe Zeynep Eryavuz
  • + 1 author

17 November 2025

Objective: We sought to assess the diagnostic performance of quantitative bone SPECT/CT standardized uptake values (SUVs) in diabetic foot osteomyelitis (DFO) and their associations with inflammatory biomarkers. Methods: We retrospectively reviewed 1...

  • Systematic Review
  • Open Access
1,336 Views
18 Pages

17 November 2025

Background/Objectives: Post-stroke cognitive impairment (PSCI) affects ~40% of survivors. Diffusion Tensor Imaging Analysis Along the Perivascular Space (DTI-ALPS) is a fast, contrast-free surrogate of perivascular (glymphatic-aligned) diffusivity th...

  • Article
  • Open Access
1 Citations
1,753 Views
11 Pages

17 November 2025

Background/Objectives: Acute kidney injury (AKI) is a common complication in hospitalized patients and carries a substantial risk of chronic kidney disease (CKD), dialysis dependence, and mortality. Although novel biomarkers such as NGAL, KIM-1, and...

  • Article
  • Open Access
531 Views
13 Pages

16 November 2025

Background: This study aimed to explore the key factors affecting the efficacy of local bleomycin injection by quantitatively analyzing the blood flow parameters of lesions before treatment using three-dimensional color power angiography to allow ear...

  • Article
  • Open Access
1 Citations
547 Views
13 Pages

The Clinical Role of Systemic Inflammation-Based Biomarkers in Predicting Mortality in Post-Pneumonectomy Bronchopleural Fistula: A Multicenter Retrospective Analysis

  • Omer Topaloglu,
  • Kubra Nur Kilic,
  • Sami Karapolat,
  • Elvan Senturk Topaloglu,
  • Atila Turkyilmaz,
  • Buket Kaytaz Alkas,
  • Aziz Gumus,
  • Hasan Turut and
  • Celal Tekinbas

16 November 2025

Background: Post-pneumonectomy bronchopleural fistula (PPBPF), although infrequent, represents one of the most devastating complications after pneumonectomy, carrying high morbidity and mortality. Accurate risk stratification is essential for timely...

  • Article
  • Open Access
662 Views
12 Pages

16 November 2025

Background/Objectives: Traditionally, women have been observed to have older age, more co-morbidities, and poorer long-term clinical outcomes following acute myocardial infarction (AMI) when compared to men. However, age-adjusted analyses have demons...

  • Article
  • Open Access
1 Citations
989 Views
23 Pages

Hybrid Faster R-CNN for Tooth Numbering in Periapical Radiographs Based on Fédération Dentaire Internationale System

  • Yong-Shao Su,
  • I Elizabeth Cha,
  • Yi-Cheng Mao,
  • Li-Hsin Chang,
  • Zi-Chun Kao,
  • Shun-Yuan Tien,
  • Yuan-Jin Lin,
  • Shih-Lun Chen,
  • Kuo-Chen Li and
  • Patricia Angela R. Abu

15 November 2025

Background/Objectives: Tooth numbering is essential because it allows dental clinicians to identify lesion locations during diagnosis, typically using the Fédération Dentaire Internationale system. However, accurate tooth numbering is c...

  • Article
  • Open Access
1,601 Views
19 Pages

External Validation of an Artificial Intelligence Triaging System for Chest X-Rays: A Retrospective Independent Clinical Study

  • André Coutinho Castilla,
  • Iago de Paiva D’Amorim,
  • Maria Fernanda Barbosa Wanderley,
  • Mateus Aragão Esmeraldo,
  • André Ricca Yoshida,
  • Anthony Moreno Eigier and
  • Márcio Valente Yamada Sawamura

15 November 2025

Background: Chest radiography (CXR) is the most frequently performed radiological exam worldwide, but reporting backlogs, caused by a shortage of radiologists, remain a critical challenge in emergency care. Artificial intelligence (AI) triage systems...

  • Article
  • Open Access
779 Views
16 Pages

15 November 2025

Background: Conventional CT- or US-guided radiofrequency ablation (RFA) for hepatocellular carcinoma (HCC) often limits repeat contrast-enhanced imaging and provides suboptimal intraprocedural conspicuity, which can hinder precise targeting and margi...

  • Case Report
  • Open Access
850 Views
9 Pages

PR3-ANCA Positive Behçet’s Disease with Severe Multisystem Involvement: A Diagnostic Challenge

  • Aleksandra Plavsic,
  • Snezana Arandjelovic,
  • Uros Karic,
  • Jelena Ljubicic,
  • Jovana Stanisavljevic,
  • Adi Hadzibegovic,
  • Dragan Vasin,
  • Sergej Marjanovic and
  • Rada Miskovic

15 November 2025

Background: Behçet’s disease (BD) and granulomatosis with polyangiitis (GPA) are distinct vasculitides. PR3-ANCA is considered specific for GPA, yet rare BD cases demonstrate positivity, creating diagnostic dilemmas. Case Presentation: W...

  • Review
  • Open Access
3,139 Views
17 Pages

The Blood Supply of the Stomach: Anatomical and Surgical Considerations

  • George Triantafyllou,
  • Orestis Lyros,
  • Dimitrios Schizas,
  • Nikolaos Arkadopoulos,
  • Fotis Demetriou,
  • George Tsakotos,
  • Alexandros Samolis and
  • Maria Piagkou

15 November 2025

The vascular anatomy of the stomach is both complex and highly variable, with direct implications for oncologic, bariatric, esophageal, and interventional procedures. This comprehensive review combines anatomical, radiological, and surgical evidence...

  • Article
  • Open Access
1,069 Views
10 Pages

Clinical Significance of Incidentally Detected Parotid Masses on Brain MRI and PET-CT

  • Joong Seob Lee,
  • Jeong In Jang,
  • Jee Hye Wee,
  • Jeong Wook Kang,
  • Ho Suk Kang,
  • Mi Jung Kwon and
  • Heejin Kim

14 November 2025

Background/Objectives: Parotid incidentalomas are increasingly detected during brain MRI and PET-CT, particularly in patients with serious diseases such as cancer. This study aimed to evaluate the clinical significance of incidentally identified paro...

  • Article
  • Open Access
629 Views
20 Pages

14 November 2025

Background/Objectives: Lower-grade gliomas (LGGs) are a biologically and clinically heterogeneous group of brain tumors, for which molecular stratification plays essential role in diagnosis, prognosis, and therapeutic decision-making. Conventional un...

  • Article
  • Open Access
867 Views
17 Pages

Machine Learning Reveals Novel Pediatric Heart Failure Phenotypes with Distinct Mortality and Hospitalization Outcomes

  • Muhammad Junaid Akram,
  • Asad Nawaz,
  • Lingjuan Liu,
  • Jinpeng Zhang,
  • Haixin Huang,
  • Bo Pan,
  • Yuxing Yuan and
  • Jie Tian

14 November 2025

Background: Pediatric heart failure (PHF) is a heterogeneous syndrome with high morbidity, but existing classification systems inadequately capture its developmental and pathophysiological complexity due to reliance on adult-centric parameters. Using...

  • Article
  • Open Access
807 Views
22 Pages

14 November 2025

Background: Parkinson’s disease (PD) is a degenerative neurological disorder that greatly affects motor and speech functions; therefore, early diagnosis is vital for improving patients’ quality of life. This work introduces a unified and...

  • Article
  • Open Access
1 Citations
548 Views
13 Pages

14 November 2025

Background/Objective: Fetal growth restriction (FGR) is a condition in which the fetus fails to grow as expected for gestational age, and its growth is restricted. This study aimed to investigate the role of SCUBE-1, a new ischemia marker, in the dia...

  • Article
  • Open Access
1,145 Views
24 Pages

Clinical Profiles and Mortality-Associated Risk Factors in Patients with Acute Kidney Injury from Atlixco, Puebla, Mexico

  • Nancy K. Zúñiga-Fernández,
  • Pedro A. Gaspar-Mendoza,
  • Lizeth Torres-Pineda,
  • Elizabeth Baez-Baez,
  • Karina Alvarado-Dardón,
  • Karla V. Gutiérrez-de Anda,
  • Jorge Ayón-Aguilar,
  • Rubí Romo-Rodríguez,
  • Rosana Pelayo and
  • Diana Casique-Aguirre

14 November 2025

Background: Acute Kidney Injury (AKI) is characterized by rising morbidity and mortality rates, along with significant financial costs associated with its treatment, positioning it as a priority health challenge. Difficult access to accurate biomarke...

  • Article
  • Open Access
1 Citations
1,393 Views
24 Pages

An Integrated Architecture for Colorectal Polyp Segmentation: The µ-Net Framework with Explainable AI

  • Mehedi Hasan Emon,
  • Proloy Kumar Mondal,
  • Md Ariful Islam Mozumder,
  • Hee Cheol Kim,
  • Maria Lapina,
  • Mikhail Babenko and
  • Mohammed Saleh Ali Muthanna

14 November 2025

Objectives: Colorectal cancer (CRC) is the second-deadliest cancer globally, with an estimated 52,900 additional deaths expected in the United States by 2025. Early detection through colonoscopy significantly reduces CRC mortality by enabling the rem...

  • Article
  • Open Access
1,256 Views
14 Pages

14 November 2025

Background: The optimal number of electrodiagnostic tests required to confirm carpal tunnel syndrome (CTS) has not been systematically evaluated. While single comparative latency study (COLS) is commonly used, it remains unclear whether diagnostic ac...

  • Article
  • Open Access
1,048 Views
18 Pages

Identification of Risk Factors in Patients with Recurrent Cystitis May Improve Individualized Management

  • Jakhongir F. Alidjanov,
  • Ulugbek A. Khudaybergenov,
  • Khurshid B. Khudayberdiev,
  • Jennifer Kranz,
  • Laila Schneidewind,
  • Fabian P. Stangl,
  • José Medina-Polo,
  • Adrian Pilatz,
  • Tommaso Cai and
  • Truls E. Bjerklund Johansen
  • + 2 authors

14 November 2025

Background/Objectives: Management of acute episodes of lower urinary tract infection (LUTI) depends on whether they are sporadic or recurrent. We aimed to define factors that differentiate patients with acute sporadic cystitis (AC) from those with re...

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Diagnostics - ISSN 2075-4418