2025 November-2 - 117 articles
Background and Clinical Significance: The paper investigates the use of the Histolog® Scanner, a confocal microscopy–based device, as a potential tool for intraoperative neuropathological diagnosis of brain tumors. Traditional intraoperativ...
Background/Objectives: This study aimed to determine the prevalence of malnutrition and sarcopenia risk among patients hospitalized in gastroenterology clinics across different geographical regions of Turkey, to identify their risk factors, and to ev...
Background: Depression is a prevalent mental health condition among older adults and may be linked to multiple systemic and functional factors. Emerging evidence suggests a bidirectional relationship between depressive symptoms and poor oral health,...
Objective: To evaluate changes in maxillary incisor inclination before and after orthodontic treatment in adults with different vertical facial patterns (normodivergent, hypodivergent, hyperdivergent) and to assess the relationship of incisor inclina...
Background/Objectives: Periodontitis is a chronic inflammatory disease initiated by dysbiotic biofilms and driven by host immune dysregulation, leading to connective tissue destruction and alveolar bone loss. Its early diagnosis is closely linked to...
Background: The diagnosis of abdominal tuberculous lymphadenopathy (ATBL) remains challenging in clinical practice. Patients with ATBL and HIV infection may have atypical clinical and computed tomography (CT) features. The aim of this study was to in...
Background/Objectives: The purpose of this study was to evaluate the implementation of ultra-widefield swept-source optical coherence tomography (SS-OCT) in characterizing peripheral retinal degenerations and rhegmatogenous lesions, and to assess its...
Background/Objectives: Chronic endometritis (CE) is a well-known risk factor for recurrent implantation failure. However, the traditional approach to CE diagnosis has several drawbacks. On the other hand, there is a lot of evidence that some clinical...
Background/Objectives: The timely diagnosis of schistosomiasis and strongyloidiasis is important because of their potentially severe, even lethal, consequences. European diagnostic laboratories must comply with the European In Vitro Diagnostic (IVD)...
Background and Objectives: Despite major advances in medical science and critical care, sepsis remains a leading cause of morbidity and mortality worldwide: it arises from dysregulated host response to infections and may culminate in organ dysfunctio...
Background/Objectives: This retrospective observational cohort examined whether opportunistic CT-derived Hounsfield units (HU) of the lumbar spine and proximal femur together with serum 25-OH-vitamin D can predict sacral insufficiency fractures (SIF)...
Background/Objectives: Assessment of the midpalatine suture is vital for making clinical decisions regarding the correction of transverse growth discrepancies of the maxilla. Several studies have used Cone Beam Computed Tomography (CBCT) to evaluate...
Background/Objectives: Accurate segmentation of skin lesions is essential for early skin cancer detection. However, traditional CNNs are limited in modeling long-range dependencies, leading to poor performance on lesions with complex shapes. Methods:...
Background: Accurate sex estimation is crucial in forensic identification when DNA analysis is impractical or remains are fragmented. Traditional anthropometric approaches often rely on single bone measurements and yield moderate levels of accuracy....
Background/Objectives: Diabetes is Mexico’s second-leading cause of death, primary cause of disability, and diabetic retinopathy (DR) associated with this disease is the leading cause of vision loss among the working population. Limited healthc...
Background: Cardiovascular disease (CVD) in pregnancy is a major cause of maternal morbidity and mortality, accounting for nearly one-third of pregnancy-related deaths worldwide. Physiological adaptations—expanded plasma volume, increased cardi...
Background/Objectives: The Montreal Cognitive Assessment (MoCA) is a widely used cognitive screening tool designed to detect cognitive impairment. However, evidence indicates that the original cut-off score of 26 and the one-point correction for low...
The drivers of healthcare inequalities, often interlinked, include socioeconomic status, geographic barriers, gender, age, and ethnicity [...]
Patellofemoral instability (PFI) is a multifactorial orthopedic condition affecting predominantly young and active individuals. Accurate diagnosis and personalized treatment planning remain challenging due to the complex interplay of anatomical and b...
Background/Objectives: We aimed to characterize the microvascular imaging (MI) to demonstrate in hepatic hemangiomas in routine practice and to quantify the impact of lesion depth on MI signal detectability, and—when present—describe the...
Objectives: The purpose of this study is to develop and verify a sandwich-type lateral flow immunoassay (LFA) integrated with a smartphone, enabling semi-quantitative 25-hydroxyvitamin D [25(OH)D] measurement including automated image analysis functi...
Background/Objectives: This study aimed to investigate specific biomarkers of oxidative stress within gingival crevicular fluid (GCF) and plasma obtained from children with leukemia compared to healthy subjects, in relation to the oral hygiene status...
Background: Radiomics enables the extraction of quantitative imaging biomarkers that can non-invasively capture tumor biology and treatment response. Delta-radiomics, by assessing temporal changes in radiomic features, may improve reproducibility and...
Background/Objectives: Type 2 diabetes mellitus (T2DM) is a prevalent chronic disease frequently associated with impaired nutritional status and reduced health-related quality of life (HRQoL), especially in older adults. Alongside pharmacological tre...
Background/Objectives: The aim of this study was to classify nailfold videocapillaroscopy (NVC) images obtained from patients with systemic sclerosis (SSc) and healthy individuals using deep learning methods. Methods: Between January and June 2025, 1...
Background/Objectives: The stellate ganglion (SG), formed by the fusion of the inferior cervical and first thoracic sympathetic ganglia in approximately 80% of individuals, plays crucial roles in cardiac innervation, pain management, and autonomic re...
Background: Chronic Obstructive Pulmonary Disease (COPD) remains a leading cause of morbidity and mortality worldwide, particularly in low- and middle-income countries (LMICs), where both tobacco and biomass smoke exposure are major risk factors. Whi...
Background/Objectives: Rotator cuff calcific tendinitis (RCCT) is a common cause of shoulder pain. The role of acromial morphology in RCCT pathogenesis remains unclear. This study aimed to evaluate association between acromial morphological parameter...
Background/objectives: Sjögren’s disease (SjD) is an autoimmune disorder characterized by lymphocytic infiltration and inflammation leading to exocrine gland dysfunction. Th17 cells play a central role in autoimmune pathology and are defin...
Background/Objectives: Autoimmune metaplastic atrophic gastritis (AMAG) is a chronic, autoimmune-mediated condition associated with increased risk of malignancy and nutritional deficiencies, yet diagnostic and follow-up processes remain inconsistent...
Objective: We sought to assess the diagnostic performance of quantitative bone SPECT/CT standardized uptake values (SUVs) in diabetic foot osteomyelitis (DFO) and their associations with inflammatory biomarkers. Methods: We retrospectively reviewed 1...
Background/Objectives: Post-stroke cognitive impairment (PSCI) affects ~40% of survivors. Diffusion Tensor Imaging Analysis Along the Perivascular Space (DTI-ALPS) is a fast, contrast-free surrogate of perivascular (glymphatic-aligned) diffusivity th...
Background/Objectives: Acute kidney injury (AKI) is a common complication in hospitalized patients and carries a substantial risk of chronic kidney disease (CKD), dialysis dependence, and mortality. Although novel biomarkers such as NGAL, KIM-1, and...
Background: This study aimed to explore the key factors affecting the efficacy of local bleomycin injection by quantitatively analyzing the blood flow parameters of lesions before treatment using three-dimensional color power angiography to allow ear...
Background: Post-pneumonectomy bronchopleural fistula (PPBPF), although infrequent, represents one of the most devastating complications after pneumonectomy, carrying high morbidity and mortality. Accurate risk stratification is essential for timely...
Background/Objectives: Traditionally, women have been observed to have older age, more co-morbidities, and poorer long-term clinical outcomes following acute myocardial infarction (AMI) when compared to men. However, age-adjusted analyses have demons...
Background/Objectives: Tooth numbering is essential because it allows dental clinicians to identify lesion locations during diagnosis, typically using the Fédération Dentaire Internationale system. However, accurate tooth numbering is c...
Background: Chest radiography (CXR) is the most frequently performed radiological exam worldwide, but reporting backlogs, caused by a shortage of radiologists, remain a critical challenge in emergency care. Artificial intelligence (AI) triage systems...
Background: Conventional CT- or US-guided radiofrequency ablation (RFA) for hepatocellular carcinoma (HCC) often limits repeat contrast-enhanced imaging and provides suboptimal intraprocedural conspicuity, which can hinder precise targeting and margi...
Background: Behçet’s disease (BD) and granulomatosis with polyangiitis (GPA) are distinct vasculitides. PR3-ANCA is considered specific for GPA, yet rare BD cases demonstrate positivity, creating diagnostic dilemmas. Case Presentation: W...
The vascular anatomy of the stomach is both complex and highly variable, with direct implications for oncologic, bariatric, esophageal, and interventional procedures. This comprehensive review combines anatomical, radiological, and surgical evidence...
Background/Objectives: Parotid incidentalomas are increasingly detected during brain MRI and PET-CT, particularly in patients with serious diseases such as cancer. This study aimed to evaluate the clinical significance of incidentally identified paro...
Background/Objectives: Lower-grade gliomas (LGGs) are a biologically and clinically heterogeneous group of brain tumors, for which molecular stratification plays essential role in diagnosis, prognosis, and therapeutic decision-making. Conventional un...
Background: Pediatric heart failure (PHF) is a heterogeneous syndrome with high morbidity, but existing classification systems inadequately capture its developmental and pathophysiological complexity due to reliance on adult-centric parameters. Using...
Background: Parkinson’s disease (PD) is a degenerative neurological disorder that greatly affects motor and speech functions; therefore, early diagnosis is vital for improving patients’ quality of life. This work introduces a unified and...
Background/Objective: Fetal growth restriction (FGR) is a condition in which the fetus fails to grow as expected for gestational age, and its growth is restricted. This study aimed to investigate the role of SCUBE-1, a new ischemia marker, in the dia...
Background: Acute Kidney Injury (AKI) is characterized by rising morbidity and mortality rates, along with significant financial costs associated with its treatment, positioning it as a priority health challenge. Difficult access to accurate biomarke...
Objectives: Colorectal cancer (CRC) is the second-deadliest cancer globally, with an estimated 52,900 additional deaths expected in the United States by 2025. Early detection through colonoscopy significantly reduces CRC mortality by enabling the rem...
Background: The optimal number of electrodiagnostic tests required to confirm carpal tunnel syndrome (CTS) has not been systematically evaluated. While single comparative latency study (COLS) is commonly used, it remains unclear whether diagnostic ac...
Background/Objectives: Management of acute episodes of lower urinary tract infection (LUTI) depends on whether they are sporadic or recurrent. We aimed to define factors that differentiate patients with acute sporadic cystitis (AC) from those with re...
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