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Molecules, Volume 28, Issue 13

July-1 2023 - 406 articles

Cover Story: Cysteine redox chemistry is widely used in nature to direct protein assembly, and in recent years it has inspired chemists to design self-assembling peptides too. In this concise review, we describe the progress in the field focusing on the recent advancements that make use of Cys thiol–disulfide redox chemistry to modulate hydrogelation of various peptide classes. View this paper
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Articles (406)

  • Article
  • Open Access
11 Citations
3,087 Views
23 Pages

Quality Marker Discovery and Quality Evaluation of Eucommia ulmoides Pollen Using UPLC-QTOF-MS Combined with a DPPH-HPLC Antioxidant Activity Screening Method

  • Fengqian Guo,
  • Yichun Yang,
  • Yu Duan,
  • Chun Li,
  • Huimin Gao,
  • Hongyu Liu,
  • Qiping Cui,
  • Zhongyuan Guo,
  • Xiaoqian Liu and
  • Zhimin Wang

Pollen, as an important component of Eucommia ulmoides (EUP), is rich in nutrients and is receiving increasing attention. At present, there are no reports on research related to the chemical composition and quality standards of EUP, and there are sig...

  • Article
  • Open Access
5 Citations
2,114 Views
14 Pages

The main aim of the current project was to investigate the effect of the linker size in 4-alkyl-5-aryl-1,2,4-triazole-3-thione derivatives, known as a group of antiepileptic drug candidates, on their affinity towards voltage-gated sodium channels (VG...

  • Article
  • Open Access
10 Citations
3,285 Views
14 Pages

Optimization of the Extraction Conditions of Bioactive Compounds from Ocimum basilicum Leaves Using Ultrasound-Assisted Extraction via a Sonotrode

  • Carolina Aloisio,
  • María del Carmen Razola-Díaz,
  • María José Aznar-Ramos,
  • Marcela R. Longhi,
  • Alfonsina E. Andreatta and
  • Vito Verardo

Sweet basil (Ocimum basilicum) leaves are rich in bioactive compounds that present therapeutic benefits for human health. Ultrasonic-assisted extraction (UAE) is frequently used to obtain phenolic compounds from plants/herbal sources. However, few wo...

  • Article
  • Open Access
22 Citations
3,287 Views
27 Pages

In Vitro Bioaccessibility Assessment of Phenolic Compounds from Encapsulated Grape Pomace Extract by Ionic Gelation

  • Josipa Martinović,
  • Jasmina Lukinac,
  • Marko Jukić,
  • Rita Ambrus,
  • Mirela Planinić,
  • Gordana Šelo,
  • Ana-Marija Klarić,
  • Gabriela Perković and
  • Ana Bucić-Kojić

Grape pomace is a by-product of winemaking characterized by a rich chemical composition from which phenolics stand out. Phenolics are health-promoting agents, and their beneficial effects depend on their bioaccessibility, which is influenced by gastr...

  • Article
  • Open Access
6 Citations
4,166 Views
26 Pages

Mechanochemical Studies on Coupling of Hydrazines and Hydrazine Amides with Phenolic and Furanyl Aldehydes—Hydrazones with Antileishmanial and Antibacterial Activities

  • Anna Kapusterynska,
  • Christian Bijani,
  • Damian Paliwoda,
  • Laure Vendier,
  • Valérie Bourdon,
  • Nicolas Imbert,
  • Sandrine Cojean,
  • Philippe Marie Loiseau,
  • Deborah Recchia and
  • Viola Camilla Scoffone
  • + 6 authors

Hydrazone compounds represent an important area of research that includes, among others, synthetic approaches and biological studies. A series of 17 hydrazones have been synthesized by mechanochemical means. The fragments chosen were phenolic and fur...

  • Article
  • Open Access
3 Citations
2,842 Views
16 Pages

A broadband EPR spectrometer is an instrument that can be tuned to many microwave frequencies over several octaves. Its purpose is the collection of multi-frequency data, whose global analysis affords interpretation of complex spectra by means of dec...

  • Perspective
  • Open Access
30 Citations
6,085 Views
13 Pages

Review Insights on Salivary Proteomics Biomarkers in Oral Cancer Detection and Diagnosis

  • Vidhya Rekha Umapathy,
  • Prabhu Manickam Natarajan and
  • Bhuminathan Swamikannu

Early detection is crucial for the treatment and prognosis of oral cancer, a potentially lethal condition. Tumor markers are abnormal biological byproducts produced by malignant cells that may be found and analyzed in a variety of bodily fluids, incl...

  • Article
  • Open Access
22 Citations
2,706 Views
19 Pages

To find potential α-glucosidase inhibitors, indolo[1,2-b]isoquinoline derivatives (1–20) were screened for their α-glucosidase inhibitory effects. All derivatives presented potential α-glucosidase inhibitory effects with IC50 values of 3.44 ± 0.36~41...

  • Article
  • Open Access
11 Citations
2,929 Views
14 Pages

When added to mushroom growing substrates, edible and medicinal herbs affect the mushrooms’ nutritional and medicinal value. In this study, polysaccharides (P0OP-I and P15OP-I) were extracted and purified from oyster mushrooms grown on substrat...

  • Article
  • Open Access
2,031 Views
10 Pages

Activity Enhancement of Ferrierite in Dimethyl Ether Carbonylation Reactions through Recrystallization with Sodium Oleate

  • Jiangang Lv,
  • Long Chen,
  • Chong Chen,
  • Yunzheng Wang,
  • Di Wang,
  • Huaqian Sun and
  • Weimin Yang

Methyl acetate (MA) has a wide range of applications as an important industrial chemical. Traditional MOR zeolite for carbonylation of DME to MA accumulated carbon easily because of a 12-membered ring (12 MR) channel. In this work, we innovatively de...

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Molecules - ISSN 1420-3049