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21 Results Found

  • Article
  • Open Access
12 Citations
3,884 Views
8 Pages

Curiosity Killed the Cat but Not Memory: Enhanced Performance in High-Curiosity States

  • Caterina Padulo,
  • Erika Marascia,
  • Nadia Conte,
  • Noemi Passarello and ,
  • Laura Mandolesi and
  • Beth Fairfield
  • + 1 author+ 0 author

Curiosity benefits memory for target information and may also benefit memory for incidental information presented during curiosity states. However, it is not known whether incidental curiosity-enhanced memory depends on or is affected by the valence...

(This article belongs to the Special Issue Novel Approaches to Memory and Aging)
  • Review
  • Open Access
24 Citations
10,919 Views
19 Pages

Human Adipose-Derived Stromal/Stem Cell Culture and Analysis Methods for Adipose Tissue Modeling In Vitro: A Systematic Review

  • Peyton Gibler,
  • Jeffrey Gimble,
  • Katie Hamel,
  • Emma Rogers and ,
  • Michael Henderson,
  • Xiying Wu,
  • Spencer Olesky and
  • Trivia Frazier
  • + 3 authors+ 0 author

3 June 2021

Human adipose-derived stromal/stem cells (hASC) are widely used for in vitro modeling of physiologically relevant human adipose tissue. These models are useful for the development of tissue constructs for soft tissue regeneration and 3-dimensional (3...

(This article belongs to the Special Issue Human Adipose Stem Cells)
  • Review
  • Open Access
40 Citations
11,856 Views
21 Pages

Clinical Translational Potential in Skin Wound Regeneration for Adipose-Derived, Blood-Derived, and Cellulose Materials: Cells, Exosomes, and Hydrogels

  • Trivia Frazier,
  • Andrea Alarcon,
  • Xiying Wu,
  • Omair A. Mohiuddin and ,
  • Jessica M. Motherwell,
  • Anders H. Carlsson,
  • Robert J. Christy,
  • Judson V. Edwards,
  • Robert T. Mackin and
  • Jeffrey M. Gimble
  • + 10 authors+ 5 authors

27 September 2020

Acute and chronic skin wounds due to burns, pressure injuries, and trauma represent a substantial challenge to healthcare delivery with particular impacts on geriatric, paraplegic, and quadriplegic demographics worldwide. Nevertheless, the current st...

(This article belongs to the Collection Mesenchymal Stem Cell Fate and Potential Therapy)
  • Brief Report
  • Open Access
43 Citations
6,842 Views
13 Pages

Human Platelet Lysate as a Functional Substitute for Fetal Bovine Serum in the Culture of Human Adipose Derived Stromal/Stem Cells

  • Mathew Cowper,
  • Trivia Frazier,
  • Xiying Wu,
  • J. Lowry Curley and ,
  • Michelle H. Ma,
  • Omair A. Mohiuddin,
  • Marilyn Dietrich,
  • Michelle McCarthy,
  • Joanna Bukowska and
  • Jeffrey M. Gimble
  • + 5 authors+ 0 author

15 July 2019

Introduction: Adipose derived stromal/stem cells (ASCs) hold potential as cell therapeutics for a wide range of disease states; however, many expansion protocols rely on the use of fetal bovine serum (FBS) as a cell culture nutrient supplement. The c...

(This article belongs to the Special Issue Adipose-Derived Stromal/Stem Cells)
  • Article
  • Open Access
36 Citations
7,902 Views
29 Pages

Decellularized Human Umbilical Tissue-Derived Hydrogels Promote Proliferation and Chondrogenic Differentiation of Mesenchymal Stem Cells

  • Faiza Ramzan,
  • Sobia Ekram,
  • Trivia Frazier,
  • Asmat Salim and ,
  • Omair Anwar Mohiuddin and
  • Irfan Khan
  • + 1 author+ 0 author

Tissue engineering is a promising approach for the repair and regeneration of cartilaginous tissue. Appropriate three-dimensional scaffolding materials that mimic cartilage are ideal for the repair of chondral defects. The emerging decellularized tis...

(This article belongs to the Section Regenerative Engineering)
  • Review
  • Open Access
5 Citations
5,650 Views
23 Pages

Adipose Tissue in Breast Cancer Microphysiological Models to Capture Human Diversity in Preclinical Models

  • Katie M. Hamel,
  • Trivia P. Frazier,
  • Christopher Williams,
  • Tamika Duplessis and ,
  • Brian G. Rowan,
  • Jeffrey M. Gimble and
  • Cecilia G. Sanchez
  • + 2 authors+ 0 author

27 February 2024

Female breast cancer accounts for 15.2% of all new cancer cases in the United States, with a continuing increase in incidence despite efforts to discover new targeted therapies. With an approximate failure rate of 85% for therapies in the early phase...

(This article belongs to the Section Biochemistry)
  • Article
  • Open Access
205 Views
16 Pages

Development of Hydrogel-Cellulose Nanofiber Hybrid Scaffolds for Potential Cutaneous Wound-Healing Applications

  • Judson V. Edwards,
  • Nicolette T. Prevost,
  • Haley Lassiter,
  • Katie Hamel and ,
  • Michael W. Easson,
  • Jacobs H. Jordan,
  • Emma Rogers,
  • Jordan Robinson,
  • Trivia Frazier and
  • Cecilia G. Sanchez
  • + 5 authors+ 0 author

28 October 2026

Cellulose nanofibrils (CNFs) and TEMPO-oxidized cellulose nanofibrils (TOCNFs) are hydrated, high-aspect-ratio biomaterials with tunable physicochemical properties, whereas human-derived extracellular matrix (ECM) hydrogels provide matrix-associated...

(This article belongs to the Section Materials Science)
  • Article
  • Open Access
3 Citations
3,830 Views
14 Pages

In the two-stage open-domain question answering (OpenQA) systems, the retriever identifies a subset of relevant passages, which the reader then uses to extract or generate answers. However, the performance of OpenQA systems is often hindered by issue...

(This article belongs to the Section Internet of Things)
  • Article
  • Open Access
11 Citations
13,278 Views
16 Pages

13 February 2023

Once a niche part of the cyber community, video games today represent one of the major industries and “the combination of technology and spiritualist narratives”. In the cyberspace dedicated to video game trivia, we can find intimate repo...

(This article belongs to the Special Issue Religion, Science and Technology in Pantheism, Animism and Paganism)
  • Article
  • Open Access
3,044 Views
12 Pages

Quantum-Inspired Fusion for Open-Domain Question Answering

  • Ruixue Duan,
  • Xin Liu,
  • Zhigang Ding and
  • Yangsen Zhang

21 October 2024

Open-domain question-answering systems need models capable of referencing multiple passages simultaneously to generate accurate answers. The Rational Fusion-in-Decoder (RFiD) model focuses on differentiating between causal relationships and spurious...

(This article belongs to the Special Issue Data Mining Applied in Natural Language Processing)
  • Article
  • Open Access
3 Citations
4,469 Views
14 Pages

21 October 2025

Uncertainty quantification (UQ) for open-ended language generation remains a critical yet underexplored challenge, particularly in settings where token-level log-probabilities are available during decoding. We present Token-Entropy Conformal Predicti...

(This article belongs to the Topic Challenges and Solutions in Large Language Models)
  • Article
  • Open Access
8 Citations
7,819 Views
17 Pages

29 November 2020

Although Shakespeare and his plays have been a frequent subject of videogame adaptations in the past, these have often been confined to either theatre-making games (which present the staging of Shakespeare plays using the mechanisms of strategy or si...

(This article belongs to the Special Issue The Art of Adaptation in Film and Video Games)
  • Article
  • Open Access
6 Citations
4,705 Views
23 Pages

Dishonesty is an interpersonal process that relies on sophisticated socio-cognitive mechanisms embedded in a complex network of individual and contextual factors. The present study examined parental rearing practices, bilingualism, socioeconomic stat...

(This article belongs to the Special Issue Factors Related to School Coexistence at Different Educational Stages)
  • Article
  • Open Access
26 Citations
16,596 Views
26 Pages

15 May 2020

In a design department’s practice course there are often group exercises that include intensive interactions between students in the classroom or in the internship factory. In addition, students will deepen the interaction between peers due to...

(This article belongs to the Special Issue Selected Papers from the Eurasian Conference on Educational Innovation 2020)
  • Article
  • Open Access
7 Citations
4,272 Views
21 Pages

23 February 2023

Safety researchers increasingly recognize the impacts of task-induced fatigue on vehicle driving behavior. The current study (N = 180) explored the use of a multidimensional fatigue measure, the Driver Fatigue Questionnaire (DFQ), to test the impacts...

(This article belongs to the Special Issue Human Factors in Road Safety and Mobility)
  • Article
  • Open Access
5 Citations
3,049 Views
18 Pages

Students claim that multiple-choice questions can be tricky, particularly those with competitive incorrect choices or choices like none-of-the-above (NOTA). Additionally, assessment researchers suggest that using NOTA is problematic for assessment. I...

(This article belongs to the Special Issue The Intersection of Metacognition and Intelligence)
  • Data Descriptor
  • Open Access
2 Citations
3,383 Views
14 Pages

25 June 2024

In the age of abundant digital content, children and adolescents face the challenge of developing new information literacy competencies, particularly those pertaining to online inquiry, in order to thrive academically and personally. This article add...

(This article belongs to the Special Issue Data Mining and Computational Intelligence for E-Learning and Education—2nd Edition)
  • Article
  • Open Access
7 Citations
4,413 Views
19 Pages

26 July 2024

Theoretical subjects, such as history, usually do not attract the interest of students and as a result educational games and serious games that use augmented reality (AR) are increasingly used as a means of supporting education. It is believed that t...

(This article belongs to the Section Computing and Artificial Intelligence)
  • Article
  • Open Access
1 Citations
335 Views
19 Pages

2 October 2026

Selective prediction requires a statistically reliable rule for deciding which model outputs can be returned while controlling the error rate among accepted predictions. In large language model (LLM) applications, uncertainty scores provide useful ra...

  • Article
  • Open Access
11 Citations
4,570 Views
23 Pages

KG-EGV: A Framework for Question Answering with Integrated Knowledge Graphs and Large Language Models

  • Kun Hou,
  • Jingyuan Li,
  • Yingying Liu,
  • Shiqi Sun and ,
  • Haoliang Zhang and
  • Haiyang Jiang
  • + 1 author+ 0 author

7 December 2024

Despite the remarkable progress of large language models (LLMs) in understanding and generating unstructured text, their application in structured data domains and their multi-role capabilities remain underexplored. In particular, utilizing LLMs to p...

(This article belongs to the Special Issue Big Data Analytics and Information Technology for Smart Cities and Citizen Wellbeing)
  • Article
  • Open Access
985 Views
27 Pages

19 April 2026

Retrieval-Augmented Generation (RAG) has become an important paradigm for knowledge-intensive natural language processing, as it enables Large Language Models (LLMs) to access external evidence beyond their parametric memory. However, existing RAG pi...

(This article belongs to the Special Issue Natural Language Processing (NLP): Technologies and Applications)