Human Adipose Stem Cells

Dear Colleagues,

The development of obesity and associated metabolic diseases is a major health problem. Three types of adipocytes, i.e., white, brown and beige/brite, regulate the energy intake and energy expenditure balance. Hence, there is a requirement to characterize human adipose stem cells (hASCs) generating these different types of adipocytes to deliver better insight into obesity. This necessitates the use of relevant cell models and culture conditions recapitulating better adipocyte biology in vivo. The potential of hASCs to counteract obesity in animal models remains to be determined.

This Special Issue will examine identification of hASC subpopulations; methods to isolate and to maintain hASCs ex vivo; sex–gender, fat depot, and aging effects on hASC features; cell models for hASC differentiation, for antiobesity drug screening; in vitro culture conditions and hASC bioengineering; and in vivo models to investigate the potential of hASCs to counteract obesity.

Dr. Christian Dani
Guest Editor

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