Adipose-Derived Stromal/Stem Cells

Dear Colleagues,

Adipose tissue is a rich, ubiquitous and easily accessible source for multipotent stromal/stem cells (adipose-derived stromal/stem cells, ASCs). Isolated ASCs are a heterogeneous preparation consisting of several subpopulations of stromal/stem and precursor cells. Furthermore, donor-specific differences in ASC isolations and the lack of culture standardization impede the comparison of results from different studies.

ASCs are already used in different in vivo models and clinical trials to investigate their ability to enhance tissue and organ regeneration. Nevertheless, many questions concerning their counterparts and biology in situ, their differentiation potential in vitro and in vivo, and also the mechanisms of regeneration (paracrine effects including regeneration promoting factors and extracellular vesicles, differentiation, immunomodulation) are not completely understood or remain unsolved.

Therefore, this Special Issue welcomes original research and review papers addressing:

1. Isolation and characterization of ASC subpopulations
2. Characterization of donor-specific differences
3. Characterization of extracellular vesicles and exosomes isolated from ASC
4. In vitro preconditioning regimens to enhance their regenerative potential
5. In vivo models: Enhancement of organ and tissue regeneration after ASC transplantation

Prof. Dr. Patrick C. Baer
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cells is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.