Random walks (RWs) have been important in statistical physics and can describe the statistical properties of various processes in physical, chemical, and biological systems. In this study, we have proposed a self-interacting random walk model in a co...
Recent investigations on 3D chromatin folding revealed that the eukaryote genomes are both highly compartmentalized and extremely dynamic. This review presents the most recent advances in topological domains’ organization of the eukaryote genomes and...
Despite the rapid adoption of artificial intelligence (AI) on a global scale, a comprehensive framework that maps its end-to-end value chain is missing. The presented study employed a multi-layered framework to analyze the value creation and delivery...
The objective of this study was to assess the transverse maxillary skeletal, dental, and nasal effects of quad-helix treatment (slow maxillary expansion) in comparison to an untreated group. This study was performed on 24 patients. Before and after t...
We present a computer simulation study of helix folding in alanine homopeptides (ALA)n of length n = 5, 8, 15, and 21 residues. Based on multi-microsecond molecular dynamics simulations at room temperature, we found helix populations and relaxation t...
Digitization and innovation supported by various innovation systems have become key factors in the sustainable development of companies, countries (including UE countries), and the economy as a whole. The primary objective of this study is to explore...
Background: The aim of the present study was to compare the vertical dimension changes, before and after treatment, in two groups of growing patients, one group treated with clear aligner therapy versus a group treated with Quad-helix and bite-block...
Current research studies devoted to cutting forces in drilling are oriented toward predictive model development, however, in the case of mechanistic models, the material effect on the drilling process itself is mostly not considered. This research st...
The GXXXG motif, also called the glycine zipper, is a common sequence pattern that facilitates tight packing of secondary structures, especially through helix–helix interactions in both membrane and soluble proteins. However, its overall distri...
AlphaFold2 (AF2) is a protein structure prediction program which provides accurate models. In addition to predicting structural domains, AF2 assigns intrinsically disordered regions (IDRs) by identifying regions with low prediction reliability (pLDDT...
This paper shows the surface quality results after finishing milling of AZ91D and AZ31 magnesium alloys. The study was performed for variable technological parameters: cutting speed, feed per tooth, axial depth of cut and radial depth of cut. The too...
Alzheimer’s disease is the most common progressive neurodegenerative disorder and is characterized by the presence of amyloid β (Aβ) plaques in the brain. The γ-secretase complex, which produces Aβ, is an intramembrane-cleaving protease consisting of...
15 February 2019
In Korea, cooperation between university and company is mainly encouraged by government policy as the Triple Helix’s statist model. Since 2003, the government started a variety of university financial support program, and in 2014, it reached to...
The assembly mechanism for aggregation of amyloid fibril is important and fundamental for any quantitative and physical descriptions because it needs to have a deep understanding of both molecular and statistical physics. A theoretical model with thr...
5 November 2020
Successful development and uptake of vaccine technology in a Quadruple Helix Innovative health or economic system requires a clear understanding of society’s preferences as the fourth helix. With significant financial commitments to find a safe...
In recent years, transport policy has strongly been oriented to develop more inclusive cities and to design mobility services aligned to specific users’ needs. In an attempt to guarantee an adequate level of accessibility, especially to vulnera...
Interaction with the DNA minor groove is a significant contributor to specific sequence recognition in selected families of DNA-binding proteins. Based on a statistical analysis of 3D structures of protein–DNA complexes, we propose that distort...
This article presents the methodology and tools for the econometric analysis and assessment of the innovation development of the Russian Arctic regions, under the Triple Helix concept. The econometric calculations based on this methodology allow the...
Skin aging is associated with both intrinsic and extrinsic aging, with extrinsic aging caused by environmental factors and overlaying the effects of chronological aging. The main aim of this study was to evaluate the effect of preparations containing...
30 December 2025
The caldén (Neltuma caldenia) forest, a xerophytic low-stature ecosystem in central Argentina, faces increasing threats from land use change and desertification. This study assesses the capability of full-polarimetric L-band SAR data from the...
In this study, the effect of cutting parameters on the quality of an Al/CFRP sandwich structure (aluminium alloy–carbon fibre reinforced polymer) after milling with uncoated and TiAlN-coated tools was examined. The results of the cutting force...
Understanding the inherent timescales of large bubbles in DNA is critical to a thorough comprehension of its physicochemical characteristics, as well as their potential role on helix opening and biological function. In this work, we employ the coarse...
Thermophilic proteins have various practical applications in theoretical research and in industry. In recent years, the demand for thermophilic proteins on an industrial scale has been increasing; therefore, the engineering of thermophilic proteins h...
This study investigates the moderating role of finance, accounting, and digital disruption (FADD) in the relationship between auditing and sustainability (AS) and financial reporting and ESG integration (FRESGI) through the triple-helix perspective....
In small clinical studies, the application of transcranial photobiomodulation (PBM), which typically delivers low-intensity near-infrared (NIR) to treat the brain, has led to some remarkable results in the treatment of dementia and several neurodegen...
Tibial shaft fractures are common injuries in the pediatric and adolescent populations. Elastic stable intramedullary nailing (ESIN) is the treatment of choice for cases that require surgical stabilization. A new intramedullary device, BoneHelix® (BH...
This study analyzes the relationship between the innovation capacity of Spanish companies through the ability to obtain their information through the integration of these three variables: knowledge management, emotional intelligence, and entrepreneur...
Flory’s random coil model assumes that conformational fluctuations of amino acid residues in unfolded poly(oligo)peptides and proteins are uncorrelated (isolated pair hypothesis, IPH). This implies that conformational energies, entropies and so...
Six strains of subaerial cyanobacteria were isolated from a Gomso saltern in the Republic of Korea, all of which were studied using morphological and molecular traits. Trichotorquatus salinus sp. nov. was studied using a light microscope (LM), t...
This article deals with drilling, the most common and simultaneously most important traditional machining operation, and which is significantly influenced by the properties of the machined material itself. To fully understand this process, both from...
Addressing the prevalent issue of excessive fat consumption in contemporary diets, a novel method has been devised for the preparation of an emulsion gel enriched with healthful fatty acids which possesses superior emulsification characteristics. Thi...
Fast kinetic experiments with dramatically improved time resolution have contributed significantly to understanding the fundamental processes in protein folding pathways involving the formation of a-helices and b-hairpin, contact formation, and overa...
This study applies multivariate data analysis to deconvolute the spectral profiles of the Amide III region in the infrared spectra of gingival crevicular fluid (GCF). This reveals the impact of major oral diseases, such as dental caries and periodont...
The MCM (minichromosome maintenance) protein complex forms an hexameric ring and has a key role in the replication machinery of Eukaryotes and Archaea, where it functions as the replicative helicase opening up the DNA double helix ahead of the polyme...
This retrospective study aimed to evaluate the survival rate of hybrid dental implants in different patient profiles and clinical conditions. A total of 1215 patients’ files were analyzed from patients with at least one hybrid dental implant in...
This study examines the semantic dynamics and thematic shifts in artificial intelligence (AI) ethics over time, addressing a notable gap in longitudinal research within the field. In light of the rapid evolution of AI technologies and their associate...
Abnormal aortic elasticity serves as a marker for cardiovascular mortality and has a negative impact on the left ventricular (LV) afterload. Noncompaction cardiomyopathy (NCCM) is characterized by hypertrabeculation of the LV endomyocardial wall, wit...
Adaptive reuse maintains cultural sustainability by adapting heritage buildings for new functions while retaining their original structure. The al-Nabulsi’s traditional courtyard house in Irbid, northern Jordan, represents the city’s domi...
The detection of Xylella fastidiosa in Portugal occurred through prospection in 2019 in Vila Nova de Gaia, Porto, in plants of Lavandula dentata L. Currently, in Portugal, there are 18 Xylella fastidiosa Demarcated Zones (DZs). The main objective of...
This work describes our recent PCB-based plasmonic nanostructured platform patent (US 11,828,747B2) for the detection of biomarkers in breast cancer serum (BCS). A 50 nm thin gold film (TGF) was immersion-coated on PCB (i.e., PCB-TGF) and immobilized...
Cell-penetrating peptides (CPPs) have distinct properties to translocate across cell envelope. The key property of CPPs to translocation with attached molecules has been utilized as vehicles for the delivery of several potential drug candidates that...