Dyslipidemias are one of the risk factors for cardiovascular diseases, the leading cause of death and hospitalization worldwide. One way to control cholesterol levels is to control the exogenous cholesterol intake in the body. Natural polyphenolic co...
Limonium brasiliense is a common plant on the southern coast of Brazil. The roots are traditionally used for treatment of premenstrual syndrome, menstrual disturbances and genito-urinary infections. Pharmaceutical preparations obtained from its roots...
Aminoglycosides (AGs) represent a prominent class of antibiotics widely employed for the treatment of various bacterial infections. Their widespread use has led to the emergence of antibiotic-resistant strains of bacteria, highlighting the need for a...
Analyzing huge amounts of data becomes essential in the era of Big Data, where databases are populated with hundreds of Gigabytes that must be processed to extract knowledge. Hence, classical algorithms must be adapted towards distributed computing m...
This study investigated the effects of particle size and ultrasonic parameters on the yields of bioactive compounds extracted from the leaves and inflorescences of hemp. The total flavonoid and anthocyanin contents were determined using the spectroph...
In this work, we developed an enzymatic voltammetric biosensor for the determination of catechin and gallic acid in green tea and kombucha samples. The differential pulse voltammetry (DPV) methodology was optimized regarding the amount of crude enzym...
D-DIBOA (4-hydroxy-(2H)-1,4-benzoxazin-3-(4H)-one) is an allelopathic-derived compound with interesting herbicidal, fungicidal, and insecticide properties whose production has been successfully achieved by biocatalysis using a genetically engineered...
The objective of this study was to determine the antioxidant activities of defatted walnut kernel extract (DWE) and whole walnut kernel extract (WE) in vitro and in vivo. Three spectrophotometric methods, DPPH, ABTS, and FRAP, were used in in vitro e...
Micro matrix solid phase dispersion (micro-MSPD) was optimized by response surface methodology for the extraction of polyphenols from the peel of twelve traditional and eight commercial apple varieties grown in Croatia. The optimized micro-MSPD proce...
In this study, response surface methodology (RSM) was employed for the optimization of the antioxidant potentials of red pitaya peels using independent variables: temperature (45–65 °C), ethanol concentration (70–90%, v/v) and time (8...
Iodine is an essential element for the synthesis of thyroid hormones. Iodine deficiency leads to a range of health consequences known as iodine deficiency disorders. To assess the iodine nutritional status of a population, urinary iodine (UI) is typi...
Dragon fruit peel is a by-product rich in bioactive compounds, such as polyphenols and betalains. In this study, ultrasound-assisted enzyme extraction (UAEE) was proposed to exploit this, combining the advantages of the enzymatic hydrolysis and ultra...
Previous research has primarily focused on the antioxidant effect of astaxanthin (AX) in various vegetable oils, with limited attention given to its behavior in lard. This study aimed to evaluate the degradation of AX during lard storage and to asses...
Preparation of myrtle liqueur through ethanol-based extraction is a widely employed methodology. Nevertheless, optimization of existing processes is possible, especially through a modern statistical multivariate approach. In this context, a Design of...
Bioactive compounds from olive mill pomace (OMP) were extracted through a two-step solid-liquid extraction procedure considering four factors at five levels of a central composite rotatable response surface design. The influence of the process variab...
Sea bass side streams obtained from the fish industry can be a good source of nutrients such as high-quality protein, lipids, and antioxidants. In this context, it is interesting to develop innovative approaches to extract the added-value compounds f...
The purpose of this study was to optimize the effect of particle size, time and ultrasonic intensity on the extraction of phenolic compounds and energy efficiency. Sonication was performed with a VC750 Sonics processor at the following amplitudes: 30...
Wild Physalis angulata L. has promising medicinal potential due to its rich flavonoids. However, a green analytical approach for these compounds from this plant has not yet been thoroughly optimized. Therefore, this study optimized ultrasound-assiste...
The Cauchao berry (Amomyrtus luma), native to southern Chile and Argentina, has been traditionally used in folk medicine, yet scientific evidence supporting its bioactive potential remains limited. This study aimed to optimize the extraction of bioac...
The aim of the study was to analyze the influence of the dimensions of extraction cells on the energy aspects and extraction efficiency of flavonoids from rowanberry fruits (S. aucuparia L.). The total flavonoid content was determined using the spect...
Olive pomace is a by-product of olive oil production that is toxic to the environment. The purpose of this study was to evaluate the methods of olive pomace valorization through the implementation of novel technology, the so-called microwave-assisted...
Aromatic and medicinal plants are a great source of useful bioactive compounds for use in cosmetics, drugs, and dietary supplements. This study investigated the potential of using supercritical fluid extracts obtained from Matricaria chamomilla white...
This study investigated the extraction and quantification of specific phenolic compounds, including chlorogenic acid and several pyranocoumarin derivatives, from the leaves and roots of Peucedanum japonicum. Using high-performance liquid chromatograp...
This work shows an optimized enzymatic hydrolysis of high molecular weight potato galactan yielding pectic galactan-oligosaccharides (PGOs), where endo-β-1,4-galactanase (galactanase) from Cellvibrio japonicus and Clostridium thermocellum was us...
In this study, the capacity of the ubiquitous filamentous fungus Penicillium sp. 8L2 to remove Zn(II) ions present in synthetic solutions was studied and the optimal operating conditions were obtained based on a response surface methodology (RSM). Th...
Green tea contains a variety of biologically active constituents that are widely used in the pharmaceutical and food industries. Among them, simple catechins constitute a major group of compounds that is primarily responsible for the high biologic ac...
This study investigated the impact of subcritical water extraction parameters on the polyphenols and flavonoids content in extracts made of the bark of walnut (Juglans regia L.), as well as antioxidant activity measured using the DPPH and FRAP method...
In this study, an efficient utilization and valorization of mandarin peel (Citrus unshiu Marc. var. Kuno) was investigated using innovative and green extraction techniques. The first step of this study included the extraction and analysis of the vola...
Background: Fixed-dose combinations have advanced in many therapeutic areas, including otorhinolaryngology, where hearing disorders are increasingly prevalent. Objectives: The present study focuses on developing and evaluating a new capsule combining...
The aim of this research is to analyze and develop technical methods that allow the recycling of food packaging coated in polypropylene films using solvents for the removal of the lacquer and/or aluminum layer without modifying their mechanical prope...
This study explores an eco-friendly approach to synthesizing silver nanoparticles (AgNPs) using soybean leaf extracts, employing a reaction with silver nitrate at 65 °C for 2.5 h. Optimal results were achieved at extract concentrations of 3.12 an...
The halide anions are essential for supporting life. Therefore, halide anion analyses are of paramount importance. For this reason, we have performed both qualitative and quantitative ana- lyses of halides (chloride, bromide, iodide) using the Tl(III...