Skip Content
You are currently on the new version of our website. Access the old version .

78 Results Found

  • Article
  • Open Access
12 Citations
4,605 Views
8 Pages

Sinus Mucosa Thickness Changes and Ostium Involvement after Maxillary Sinus Floor Elevation in Sinus with Septa. A Cone Beam Computed Tomography Study

  • Shingo Kato,
  • Yuki Omori,
  • Masatsugu Kanayama,
  • Atsuya Hirota,
  • Mauro Ferri,
  • Karol Alí Apaza Alccayhuaman and
  • Daniele Botticelli

21 July 2021

Background: A thickening of the sinus mucosa is observed after sinus floor augmentation. The objective of this retrospective study was to evaluate the influence of the presence of septa in the dimensional variation and ostium involvement over time of...

  • Feature Paper
  • Article
  • Open Access
6 Citations
2,738 Views
13 Pages

Influence on Implant Bone Healing of a Collagen Membrane Placed Subjacent the Sinus Mucosa—A Randomized Clinical Trial on Sinus Floor Elevation

  • Akihiro Morimoto,
  • Nobuhiro Kobayashi,
  • Mauro Ferri,
  • Giovanna Iezzi,
  • Adriano Piattelli,
  • Natalia Fortich Mesa and
  • Daniele Botticelli

8 June 2022

Background: Perforation of the sinus mucosa is quite a frequent complication that might occur during sinus floor elevation. The perforation is often protected with a collagen membrane to avoid the extrusion of graft particles within the sinus. Howeve...

  • Article
  • Open Access
21 Citations
4,442 Views
10 Pages

Post-Irradiation Sinus Mucosa Disease in Nasopharyngeal Carcinoma Patients Treated with Intensity-Modulated Proton Therapy

  • Pei-Wen Wu,
  • Chien-Chia Huang,
  • Yun-Shien Lee,
  • Yung-Chih Chou,
  • Kang-Hsing Fan,
  • Chien-Yu Lin,
  • Bing-Shen Huang,
  • Shih-Wei Yang,
  • Chi-Che Huang and
  • Joseph Tung-Chieh Chang
  • + 2 authors

4 January 2022

In the past decade, patients with nasopharyngeal cancer (NPC) have been deemed candidates for proton radiotherapy, due to the large and comprehensive target volumes and the necessity for the retention of the surrounding healthy tissues. In this study...

  • Article
  • Open Access
12 Citations
3,275 Views
11 Pages

Sinus Mucosa Thinning and Perforations after Sinus Lifting Performed with Different Xenografts: A Histological Analysis in Rabbits

  • Riccardo Favero,
  • Karol Alí Apaza Alccayhuaman,
  • Daniele Botticelli,
  • Samuel Porfirio Xavier,
  • Vitor Ferreira Balan,
  • Veronica Macchi and
  • Raffaele De Caro

28 December 2021

Background: Experimental studies have shown a progressive thinning and perforations of the sinus mucosa associated with sharpened edges and the cutting projections of graft particles used simultaneously for maxillary sinus augmentation. Hence, the ai...

  • Article
  • Open Access
7 Citations
4,128 Views
16 Pages

Influence of Anatomical Parameters on the Dimensions of the Subantral Space and Sinus Mucosa Thickening after Sinus Floor Elevation. A Retrospective Cone Beam Computed Tomography Study

  • Yuki Omori,
  • Yasushi Nakajima,
  • Hideki Imai,
  • Daichi Yonezawa,
  • Mauro Ferri,
  • Karol Alí Apaza Alccayhuaman and
  • Daniele Botticelli

24 June 2021

Background: Various anatomical parameters might influence the surgical approach for maxillary sinus floor elevation. The objective of the present study was to retrospectively evaluate the influence of anatomical parameters on the dimensions of the su...

  • Article
  • Open Access
471 Views
17 Pages

Xenograft-Induced Damage and Synechiae Formation in the Maxillary Sinus Mucosa: A Retrospective Histological Analysis in Rabbits

  • Yasushi Nakajima,
  • Karol Alí Apaza Alccayhuaman,
  • Ermenegildo Federico De Rossi,
  • Eiki Osaka,
  • Daniele Botticelli,
  • Erick Ricardo Silva,
  • Samuel Porfirio Xavier and
  • Shunsuke Baba

16 October 2025

Background: During maxillary sinus floor augmentation, the elevated sinus mucosa may come into close contact with the pristine mucosa. The presence of xenograft granules can lead to unintended mechanical and biological interactions between the two la...

  • Article
  • Open Access
1 Citations
1,776 Views
18 Pages

Analysis of Implant Osseointegration, Bone Repair, and Sinus Mucosa Integrity Using Bio-Oss® and Hyaluronic Acid-Polynucleotide Gel (Regenfast®) in Maxillary Sinus Augmentation in Rabbits

  • Hiroyuki Omori,
  • Daniele Botticelli,
  • Erick Ricardo Silva,
  • Samuel Porfirio Xavier,
  • Sérgio Luis Scombatti de Souza,
  • Kaoru Kusano and
  • Shunsuke Baba

28 June 2025

Background: The combination of polynucleotides and hyaluronic acid with bovine bone grafts in maxillary sinus lift procedures appears to be a promising strategy to enhance bone regeneration. This study aimed to analyze implant osseointegration, bone...

  • Article
  • Open Access
5 Citations
2,239 Views
14 Pages

Contribution to Bone Formation of the Schneiderian Membrane after Sinus Augmentation: A Histological Study in Rabbits

  • Su Tien Lim,
  • Kaoru Kusano,
  • Tomohide Taniyama,
  • Shigeru Sakuma,
  • Yasushi Nakajima,
  • Samuel Porfirio Xavier and
  • Shunsuke Baba

15 November 2022

Aim: to evaluate bone formation in close contact with the sinus mucosa after different periods from sinus augmentation and the influence on healing of the presence of an inward dis-placed bone window. Material and Methods: Eighteen rabbits were inclu...

  • Article
  • Open Access
2 Citations
1,364 Views
12 Pages

Inflammatory Effects of Particulate Matter Exposure on the Nasal and Paranasal Sinus Mucosa in Rats

  • Hyun-Ho Kwak,
  • Ji-Hwan Park,
  • Hyang-Sook Kim,
  • Hyun Min Lee,
  • Sung-Dong Kim,
  • Sue Jean Mun and
  • Kyu-Sup Cho

Particulate matter (PM) is a major environmental pollutant implicated in various respiratory diseases. However, its impact on the upper respiratory tract, particularly the nasal and paranasal sinus mucosa, remains poorly understood. This study aimed...

  • Feature Paper
  • Article
  • Open Access
6 Citations
2,619 Views
10 Pages

Sinus Mucosal Damage Triggered by Synthetic or Xenogeneic Bone Substitutes: A Histological Analysis in Rabbits

  • Yuki Omori,
  • Daniele Botticelli,
  • Stefano Migani,
  • Vitor Ferreira Balan,
  • Eduardo Pires Godoy and
  • Samuel Porfirio Xavier

19 November 2022

Background: It has been shown in rabbit models that the sinus mucosa in contact with graft particles might experience a progressive thinning and perforations. The phenomenon depends on the graft used. Hence, the aim of the present study was to compar...

  • Review
  • Open Access
3 Citations
2,919 Views
9 Pages

Sphenoid Sinus Mucosal Flap after Transsphenoidal Surgery—A Systematic Review

  • Piotr Sumislawski,
  • Martyna Piotrowska,
  • Jan Regelsberger,
  • Jörg Flitsch and
  • Roman Rotermund

6 February 2024

Background and Objectives: Skull base reconstruction is a crucial step during transsphenoidal surgery. Sphenoid mucosa is a mucosal membrane located in the sphenoid sinus. Preservation and lateral shifting of sphenoid mucosa as sphenoid mucosal flap...

  • Article
  • Open Access
17 Citations
4,833 Views
15 Pages

Association between Cone-Beam Computed Tomography and Histological and Immunohistochemical Features in Periapical Lesions Correlated with Thickened Maxillary Sinus Mucosa

  • Alexandra Dumitrescu,
  • Maria-Alexandra Martu,
  • Alexandru Nemtoi,
  • Ana Sirghe,
  • Liliana Chelaru,
  • Diana Tatarciuc,
  • Ana-Maria Dumitrescu and
  • Danisia Haba

19 August 2021

Background and Objectives: Odontogenic sinusitis is a frequently underestimated pathology with fewer symptoms in patients with periapical lesions, periodontal disease, or iatrogenic foreign bodies in the maxillary sinus. The aim of our study was to d...

  • Article
  • Open Access
5 Citations
3,952 Views
15 Pages

Maxillary Antrostomy Patency Following Intraoperative Use of Spray Cryotherapy

  • Veronica Trombitaș,
  • Adriana Zolog,
  • Mioriţa Toader and
  • Silviu Albu

29 December 2019

Objectives/Hypothesis: Stenosis of the middle meatus antrostomy (MMA) represents a major cause of recurrent disease following endoscopic sinus surgery (ESS). Various strategies have been developed to prevent the occurrence of MMA stenosis. The aim of...

  • Article
  • Open Access
4 Citations
5,661 Views
9 Pages

26 April 2021

Background: Various parameters are known to affect the amount and type of mucosal thickening. The aim of this retrospective study was to investigate these effects through a survey of cone-beam computed tomography (CBCT) images. CBCT scans of 150 pati...

  • Review
  • Open Access
8 Citations
7,447 Views
12 Pages

29 October 2023

Intranasal adhesions (synechiae) develop as a result of improper healing of the nasal mucosa. Their incidence ranges from 6.8% to 36% of rhinosurgical procedures. The aim of this study was to review the available publications and monographs dealing w...

  • Article
  • Open Access
1,276 Views
18 Pages

An Animal Ex Vivo Model Comparing Two Different Methods of Sinus Floor Elevation with Great Elevation Heights: Macroscopic, Microscopic and Radiological Analysis

  • Erick Rafael Fernández Castellano,
  • Lorena Benito Garzón,
  • Magaly Teresa Márquez Sánchez and
  • Javier Flores-Fraile

22 October 2024

Introduction: Maxillary sinus pneumatization increases with age and tooth loss, leading to a reduction in the maxillary alveolar ridge, which often results in insufficient bone height for the proper placement of dental implants. This study focused on...

  • Article
  • Open Access
12 Citations
3,086 Views
15 Pages

Argon Bioactivation of Implants Installed Simultaneously to Maxillary Sinus Lifting without Graft. An Experimental Study in Rabbits

  • Yuki Omori,
  • Daniele Botticelli,
  • Mauro Ferri,
  • Rafael Delgado-Ruiz,
  • Vitor Ferreira Balan and
  • Samuel Porfirio Xavier

6 September 2021

Background: The treatment of the surface of titanium implants with argon plasma improved its hydrophilicity and cell adhesion, resulting in higher bone apposition on implant and graft surfaces. The spontaneous perforation over time of the sinus mucos...

  • Article
  • Open Access
7 Citations
2,114 Views
16 Pages

Sequential Bone Repair in Rabbit Sinus Lifts Using Bio-Oss and Hyaluronic Acid–Polynucleotide Gel (Regenfast)

  • Nozomi Maniwa,
  • Samuel Porfirio Xavier,
  • Sergio Luis Scombatti de Souza,
  • Erick Ricardo Silva,
  • Daniele Botticelli,
  • Kenzo Morinaga and
  • Shunsuke Baba

28 November 2024

Background: A comprehensive investigation to associate the use of polynucleotides and hyaluronic acid with bovine bone in maxillary sinus lift procedures in rabbits has not been performed yet. The aim was to evaluate the influence of this novel assoc...

  • Review
  • Open Access
36 Citations
9,412 Views
15 Pages

Current and Alternative Therapies for Nasal Mucosa Injury: A Review

  • Jegadevswari Selvarajah,
  • Aminuddin Bin Saim,
  • Ruszymah Bt Hj Idrus and
  • Yogeswaran Lokanathan

Nasal mucosa injury can be caused by trauma, radiotherapy, chronic infection such as sinusitis, and post sinus surgery. The rate of healing and its treatment are important in the recovery of patients especially in post sinus surgery, which introduces...

  • Article
  • Open Access
7 Citations
6,679 Views
13 Pages

Association between Maxillary Posterior Teeth Periapical Odontogenic Lesions and Maxillary Sinus Mucosal Thickening: A 3D Volumetric Computed Tomography Analysis

  • Regimantas Simuntis,
  • Paulius Tušas,
  • Ričardas Kubilius,
  • Marijus Leketas,
  • Nora Šiupšinskienė and
  • Saulius Vaitkus

2 December 2020

Background: The detailed relationship between apical periodontitis and maxillary sinus mucosal thickening is still unknown. The aim of this study was to evaluate the association between maxillary posterior teeth periapical odontogenic lesions and max...

  • Article
  • Open Access
4 Citations
1,416 Views
18 Pages

Impact of Collagenated and Non-Collagenated Deproteinized Bovine Bone Mineral on Schneiderian Membrane Integrity in Rabbits

  • Rihito Yamada,
  • Samuel Porfirio Xavier,
  • Yasushi Nakajima,
  • Erick Ricardo Silva,
  • Daniele Botticelli,
  • Yuki Teranishi and
  • Shunsuke Baba

2 January 2025

Background: This investigation focused on the influence of collagen on the integrity of the Schneiderian membrane during maxillary sinus augmentation in a rabbit model. The aim of this study was to elucidate the relationship between membrane integrit...

  • Review
  • Open Access
5 Citations
2,494 Views
20 Pages

Mucosal Inflammatory Memory in Chronic Rhinosinusitis

  • Min-Seok Koo,
  • Sungmin Moon and
  • Min-Seok Rha

23 November 2024

Recent advancements in medical management, endoscopic sinus surgery, and biologics have significantly improved outcomes for patients with chronic rhinosinusitis (CRS). However, long-term recurrence is frequently observed following endoscopic sinus su...

  • Article
  • Open Access
1 Citations
2,138 Views
12 Pages

Aspergillus fumigatus is commonly found in the airway and is associated with airway inflammatory diseases. Zinc oxide (ZO) is known to be an essential microelement that facilitates fungal survival, growth, and proliferation. This study aimed to inves...

  • Article
  • Open Access
19 Citations
3,847 Views
12 Pages

Retrospective Analysis of Clinical and Radiologic Data Regarding Zygomatic Implant Rehabilitation with a Long-Term Follow-Up

  • Michele Di Cosola,
  • Andrea Ballini,
  • Khrystyna Zhurakivska,
  • Alberto Ceccarello,
  • Riccardo Nocini,
  • Annarita Malcangi,
  • Giorgio Mori,
  • Lorenzo Lo Muzio,
  • Stefania Cantore and
  • Antonio Olivo

Background: Zygomatic implants have been introduced to rehabilitate edentulous patients with severely atrophic maxillae. Their use has been reported by several studies, describing high overall survival rates at medium–long follow-up. The aim of...

  • Article
  • Open Access
13 Citations
2,343 Views
17 Pages

Healing Patterns of Non-Collagenated Bovine and Collagenated Porcine Xenografts Used for Sinus Floor Elevation: A Histological Study in Rabbits

  • Yuhei Miyauchi,
  • Takayuki Izutani,
  • Yuki Teranishi,
  • Takahisa Iida,
  • Yasushi Nakajima,
  • Samuel Porfirio Xavier and
  • Shunsuke Baba

Objective: To compare healing of collagenated and non-collagenated xenografts used for maxillary sinus floor elevation. Materials and Methods: Two different xenografts were used: deproteinized bovine bone (DBBM group) and collagenated corticocancello...

  • Article
  • Open Access
1,176 Views
14 Pages

26 August 2025

Background and Objectives: Thickening of the maxillary sinus mucosa is commonly detected in asymptomatic individuals through various radiographic techniques. This study aimed to evaluate the maxillary sinus mucosal thickness (MT), also known as Schne...

  • Case Report
  • Open Access
2 Citations
3,519 Views
12 Pages

2 August 2024

Chronic maxillary sinusitis accompanied by severe thickening of the sinus mucosa, blockage of the ostium, and patient-reported symptoms requires preoperative assessment and treatment by an otolaryngologist before maxillary sinus floor augmentation (M...

  • Brief Report
  • Open Access
1,120 Views
8 Pages

Computational Fluid Dynamics Simulations to Personalize Nasal Irrigations

  • Thomas Radulesco,
  • Dario Ebode,
  • Ralph Haddad,
  • Jerome R. Lechien,
  • Lionel Meister,
  • Stephane Gargula and
  • Justin Michel

Background/Objectives: Proper nasal irrigation techniques are essential for treating nasal and sinus conditions, influencing drug delivery efficiency and patient comfort. This study evaluates how different head positions—upright, right-tilted,...

  • Case Report
  • Open Access
3 Citations
5,237 Views
15 Pages

19 February 2024

Closing a recurrent oroantral fistula (OAF) that occurs at an infected sinus augmentation site is a challenge for clinicians. The recurrent OAF has a detrimental impact on bone regeneration and subsequent implant placement. This case report includes...

  • Article
  • Open Access
31 Citations
5,480 Views
17 Pages

Supplementation of probiotics is a promising gut microbiota-targeted therapeutic method for hyperlipidemia and atherosclerosis. However, the selection of probiotic candidate strains is still empirical. Here, we obtained a human-derived strain, Lactob...

  • Article
  • Open Access
4 Citations
2,605 Views
14 Pages

Schneiderian Membrane Collateral Damage Caused by Collagenated and Non-Collagenated Xenografts: A Histological Study in Rabbits

  • Yasushi Nakajima,
  • Daniele Botticelli,
  • Ermenegildo Federico De Rossi,
  • Vitor Ferreira Balan,
  • Eduardo Pires Godoy,
  • Erick Ricardo Silva and
  • Samuel Porfirio Xavier

26 January 2023

Background: The Schneiderian membrane (SM) that is in contact with biomaterial granules may become thinner and eventually perforate. It has been shown that these events are related to the biomaterial used. Hence, the main aim of the present study was...

  • Article
  • Open Access
2 Citations
2,191 Views
19 Pages

Impaired Coordination of the Ciliary Movement in Patients with Chronic Rhinosinusitis with Nasal Polyps: The Role of Decreased Planar Cell Polarity Protein Expression

  • Sakura Hirokane,
  • Tomohiro Kawasumi,
  • Sachio Takeno,
  • Yukako Okamoto,
  • Seita Miyamoto,
  • Rikuto Fujita,
  • Chie Ishikawa,
  • Takashi Oda,
  • Yuichiro Horibe and
  • Koji Ikegami
  • + 3 authors

21 August 2024

The planar cell polarity (PCP) of epithelial ciliated cells is essential for effective mucociliary clearance (MCC) in the sinonasal mucosa. We hypothesize that MCC coordination is impaired in nasal polyp (NP) mucosae due to the suppressed expression...

  • Article
  • Open Access
15 Citations
3,356 Views
14 Pages

Chronic Rhinosinusitis: MALDI-TOF Mass Spectrometry Microbiological Diagnosis and Electron Microscopy Analysis; Experience of the 2nd Otorhinolaryngology Clinic of Cluj-Napoca, Romania

  • Ionuț Isaia Jeican,
  • Lucian Barbu Tudoran,
  • Adrian Florea,
  • Mirela Flonta,
  • Veronica Trombitas,
  • Anda Apostol,
  • Mihai Dumitru,
  • Maria Aluaș,
  • Lia Monica Junie and
  • Silviu Albu

8 December 2020

(1) Background: Chronic rhinosinusitis (CRS) represents a wide range of infectious-inflammatory processes affecting, simultaneously, the nose and paranasal sinuses mucosa. The paper presents outcomes of the investigation of CRS microbiological charac...

  • Article
  • Open Access
8 Citations
3,045 Views
11 Pages

The Influence of Endodontic Lesions on The Clinical Evolution of Odontogenic Sinusitis—A Cohort Study

  • Marta Aleksandra Kwiatkowska,
  • Kornel Szczygielski,
  • Agnieszka Brociek-Piłczyńska,
  • Aldona Chloupek and
  • Dariusz Jurkiewicz

31 January 2023

Endodontic disease with formation of periapical lesions (PALs) is one of the most common causes of chronic odontogenic sinusitis (ODS). It requires close collaboration between otolaryngologists and dentists, but the best sequence of management is sti...

  • Article
  • Open Access
10 Citations
9,357 Views
13 Pages

A Reliable Surgical Procedure for Sinus Floor Augmentation with Antral Pseudocysts

  • Yasuhiro Nosaka,
  • Hitomi Nosaka,
  • Yasushi Nakajima,
  • Tadasuke Tanioka,
  • Daniele Botticelli and
  • Shunsuke Baba

18 October 2021

An antral pseudocyst (AP) is a common well-defined ‘dome-shaped’ faintly radiopaque lesion of the maxillary sinus, and usually does not require treatment in asymptomatic patients. However, when sinus floor augmentation is required to increase bone vo...

  • Review
  • Open Access
1 Citations
2,121 Views
10 Pages

Chronic rhinosinusitis (CRS) is a prevalent inflammatory condition of the nasal and paranasal mucosa that significantly impacts the quality of life. Postoperative inflammation and polyp recurrence remain common despite advances in endoscopic sinus su...

  • Case Report
  • Open Access
1 Citations
2,670 Views
8 Pages

Ultrasound-Assisted Removal of a Wooden Foreign Body Embedded in the Neck

  • Daniele Vitali,
  • Pietro Orlando,
  • Giandomenico Maggiore,
  • Oreste Gallo and
  • Ilaria Bindi

19 December 2023

Objectives: The deep submucosal migration of ingested foreign bodies into the pharyngolaryngeal mucosa is a sporadic event, and its management can be very challenging. In the case of the failure of endoscopic retrieval, open surgical techniques are u...

  • Review
  • Open Access
18 Citations
5,661 Views
20 Pages

Immunological Aspects of Chronic Rhinosinusitis

  • Katarzyna Czerwaty,
  • Katarzyna Piszczatowska,
  • Jacek Brzost,
  • Nils Ludwig,
  • Mirosław J. Szczepański and
  • Karolina Dżaman

29 September 2022

Chronic rhinosinusitis (CRS) is related to persistent inflammation with a dysfunctional relationship between environmental agents and the host immune system. Disturbances in the functioning of the sinus mucosa lead to common clinical symptoms. The ma...

  • Article
  • Open Access
6 Citations
3,072 Views
13 Pages

Influence of the Use of a Collagen Membrane Placed on the Bone Window after Sinus Floor Augmentation—An Experimental Study in Rabbits

  • Alessandro Perini,
  • Jose Viña-Almunia,
  • Carmen Carda,
  • José Javier Martín de Llano,
  • Daniele Botticelli and
  • Miguel Peñarrocha-Diago

12 November 2021

Background: We studied the influence on healing of a resorbable membrane covering the osteotomy site after maxillary sinus grafting, evaluated in different regions of the augmented area. Methods: Maxillary sinus augmentation was performed in 24 New Z...

  • Case Report
  • Open Access
1 Citations
10,481 Views
6 Pages

Bleach-Induced Chemical Sinusitis and Orbital Cellulitis Following Root Canal Treatment

  • Terese Huiying Low,
  • Jun Jie Seah,
  • Somasundaram Subramaniam,
  • Vijayaraj Thirunavukarasu and
  • Chew Lip Ng

The authors describe an unusual case of chemical sinusitis and orbital cellulitis secondary to a sodium hypochlorite accident in a patient who had just undergone root canal treatment. The patient presented with acute, progressive symptoms of unilater...

  • Article
  • Open Access
1 Citations
7,981 Views
13 Pages

A Double-Blinded Randomized Controlled Trial: Can Pulsed Electromagnetic Field Therapy Be a Novel Method for Treating Chronic Rhinosinusitis?

  • Nessrien Afify Abed Elrashid,
  • Olfat Ibrahim Ali,
  • Zizi M. Ibrahim,
  • Mohammed A. El Sharkawy,
  • Bodor Bin sheeha and
  • Wafaa Mahmoud Amin

14 November 2024

Background and Objectives: Pulsed electromagnetic field (PEMF) therapy offers a promising approach to treating inflammatory diseases. Its notable anti-inflammatory and antimicrobial effects and enhancement of microcirculation in the nasal mucosa make...

  • Case Report
  • Open Access
388 Views
11 Pages

Correlation of Eye Diseases with Odontogenic Foci of Infection: A Case Report Using Infrared Thermography as a Diagnostic Adjunct

  • Daria Wziątek-Kuczmik,
  • Aleksandra Mrowiec,
  • Anna Lorenc,
  • Maciej Kamiński,
  • Iwona Niedzielska,
  • Ewa Mrukwa-Kominek and
  • Armand Cholewka

15 December 2025

Introduction: Odontogenic infections may influence distant structures, including the eye. Their extension into the paranasal sinuses and orbital region can contribute to inflammatory and glaucomatous conditions. Case Report: A 46-year-old man was exa...

  • Review
  • Open Access
14 Citations
5,103 Views
24 Pages

28 October 2021

Epithelial barrier disruption and failure of epithelial repair by aberrant epithelial-mesenchymal transition (EMT)-induced basal cells observed in nasal mucosa of chronic rhinosinusitis (CRS) are speculated to play important roles in disease pathophy...

  • Article
  • Open Access
3 Citations
1,878 Views
8 Pages

Changes in Maxillary Sinus Volume and Mucosal Thickness Post Bimaxillary Advancement Procedures: A Retrospective Study

  • Paweł Piotr Grab,
  • Michał Szałwiński,
  • Piotr Rot,
  • Aldona Chloupek,
  • Maria Sobol and
  • Dariusz Jurkiewicz

11 June 2024

Background: Bimaxillary surgery is an elemental procedure in the field of cranio-maxillofacial surgery. It allows for the correction of even the most challenging cases of maxillomandibular disorders, malocclusion, facial asymmetry, and disproportion....

  • Article
  • Open Access
4 Citations
5,255 Views
11 Pages

Endoscopic Features of Chronic Rhinosinusitis in Patients with Gastroesophageal Reflux Disease

  • Kalamkas Sagandykova,
  • Nataliya Papulova,
  • Talapbek Azhenov,
  • Aliya Darbekova,
  • Bayan Aigozhina and
  • Jerome R. Lechien

2 August 2024

Chronic rhinosinusitis (CRS) is a complex inflammatory condition affecting the nasal and paranasal sinus mucosa. Gastroesophageal reflux disease (GERD) has been implicated as a potential exacerbating factor in CRS, but the specific endoscopic feature...

  • Article
  • Open Access
6 Citations
3,201 Views
19 Pages

COVID-19-Associated Rhino-Orbital Mucormycosis: Histological and Electron Microscopy Characteristics

  • Ionuț Isaia Jeican,
  • Delia Ioana Horhat,
  • Mihai Dumitru,
  • Adrian Florea,
  • Lucian Barbu-Tudoran,
  • Bogdan-Alexandru Gheban,
  • Vlad Anton,
  • Corneliu Toader,
  • Maria Aluaș and
  • Silviu Albu
  • + 3 authors

15 February 2024

COVID-19-associated rhino-orbital mucormycosis has become a new clinical entity. This study’s aim was to evaluate the histopathological and ultramicroscopic morphological aspects of this fungal infection. This was an observational retrospective...

  • Review
  • Open Access
1 Citations
3,361 Views
13 Pages

Eosinophilic Chronic Rhinosinusitis and Pathogenic Role of Protease

  • Jaehyeong Kim,
  • Sooun Kwak,
  • Juhyun Lee,
  • Il-Ho Park,
  • Seung Hoon Lee,
  • Jae Min Shin and
  • Tae Hoon Kim

12 December 2023

Chronic rhinosinusitis (CRS) is an inflammation of the nasal and paranasal sinus mucosa, and eosinophilic CRS (eCRS) is a subtype characterized by significant eosinophil infiltration and immune response by T-helper-2 cells. The pathogenesis of eCRS i...

  • Review
  • Open Access
7 Citations
3,840 Views
13 Pages

Dendritic cells (DCs) are antigen-presenting cells derived from the bone marrow that play an important role in the association between the innate and adaptive immune responses. The onset and development of chronic rhinosinusitis (CRS) involve a serio...

  • Case Report
  • Open Access
7 Citations
2,927 Views
9 Pages

Modern high-resolution volumetric tomography, commonly known as cone beam computed tomography (CBCT), is one of the most innovative imaging techniques which can provide views of anatomical structures not attainable by conventional techniques. Magneti...

  • Review
  • Open Access
1 Citations
2,081 Views
12 Pages

Management of High Urogenital Sinus in Adults: A Scoping Review

  • Muhammed A. Moukhtar Hammad,
  • Nardeen Magdy Samaan and
  • Gamal Ghoniem

22 January 2025

Background and Objectives: Persistent urogenital sinus (PUGS) is a rare congenital anomaly resulting from disruptions in urogenital development during embryogenesis. Characterized by the confluence of the vaginal canal and urethra into a single chann...

of 2