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38 Results Found

  • Review
  • Open Access
133 Citations
26,234 Views
17 Pages

Alcohol abuse is a serious medical and social problem. Although light to moderate alcohol consumption is beneficial to cardiovascular health, heavy drinking often results in organ damage and social problems. In addition, genetic susceptibility to the...

  • Review
  • Open Access
38 Citations
5,952 Views
15 Pages

The last few decades have witnessed an appalling rise in several emerging and re-emerging viral and zoonotic outbreaks. Such outbreaks are a lesson to learn from and seek insight into better disease monitoring and surveillance, thus preventing future...

  • Proceeding Paper
  • Open Access
1,436 Views
10 Pages

Public health disaster is linked positively to security and socio-economic development because epidemics and pandemics threaten human health and hurt economic and socio-political life. The outbreak of COVID-19 is an excellent example. It caused anxie...

  • Article
  • Open Access
2 Citations
3,492 Views
17 Pages

16 February 2024

Non-governmental organizations (national and international) are important actors in addressing health issues in Kenya. Sandflea/jigger infections (tungiasis) are a public health challenge that severely affect children, older adults, and other vulnera...

  • Review
  • Open Access
19 Citations
6,588 Views
36 Pages

Computer-Assisted and Data Driven Approaches for Surveillance, Drug Discovery, and Vaccine Design for the Zika Virus

  • Subhash C. Basak,
  • Subhabrata Majumdar,
  • Ashesh Nandy,
  • Proyasha Roy,
  • Tathagata Dutta,
  • Marjan Vracko and
  • Apurba K. Bhattacharjee

16 October 2019

Human life has been at the edge of catastrophe for millennia due diseases which emerge and reemerge at random. The recent outbreak of the Zika virus (ZIKV) is one such menace that shook the global public health community abruptly. Modern technologies...

  • Review
  • Open Access
23 Citations
6,242 Views
20 Pages

8 April 2024

With the pervasive consumption (currently >65% of total market shares and steadily increasing) of petroleum-derived synthetic textiles, the escalating concern of microfiber fragment (MF) pollution has emerged as a formidable menace to our ecologic...

  • Article
  • Open Access
8 Citations
3,890 Views
15 Pages

The Impact of Mental Health Predictors of Internet Addiction among Pre-Service Teachers in Ghana

  • Harry Barton Essel,
  • Dimitrios Vlachopoulos,
  • Ralph Nyadu-Addo,
  • Akosua Tachie-Menson,
  • Paa Kwame Baah and
  • Charles Owusu-Antwi

26 December 2022

This study examined the prevalence of addictive Internet behavior and its links with mental health among pre-service teachers in Ghana. A descriptive, correlational design was employed with 405 pre-service teachers from colleges of education and a pu...

  • Review
  • Open Access
64 Citations
16,843 Views
25 Pages

Plant-Derived Natural Compounds for Tick Pest Control in Livestock and Wildlife: Pragmatism or Utopia?

  • Danilo G. Quadros,
  • Tammi L. Johnson,
  • Travis R. Whitney,
  • Jonathan D. Oliver and
  • Adela S. Oliva Chávez

1 August 2020

Ticks and tick-borne diseases are a significant economic hindrance for livestock production and a menace to public health. The expansion of tick populations into new areas, the occurrence of acaricide resistance to synthetic chemical treatments, the...

  • Review
  • Open Access
63 Citations
6,168 Views
20 Pages

Mycotoxin Regulatory Status in Africa: A Decade of Weak Institutional Efforts

  • Cynthia Adaku Chilaka,
  • Jude Ejikeme Obidiegwu,
  • Augusta Chinenye Chilaka,
  • Olusegun Oladimeji Atanda and
  • Angela Mally

29 June 2022

Food safety problems are a major hindrance to achieving food security, trade, and healthy living in Africa. Fungi and their secondary metabolites, known as mycotoxins, represent an important concern in this regard. Attempts such as agricultural, stor...

  • Review
  • Open Access
22 Citations
9,440 Views
23 Pages

Mosquitoes of Etiological Concern in Kenya and Possible Control Strategies

  • Samuel Karungu,
  • Evans Atoni,
  • Joseph Ogalo,
  • Caroline Mwaliko,
  • Bernard Agwanda,
  • Zhiming Yuan and
  • Xiaomin Hu

16 June 2019

Kenya is among the most affected tropical countries with pathogen transmitting Culicidae vectors. For decades, insect vectors have contributed to the emergence and distribution of viral and parasitic pathogens. Outbreaks and diseases have a great imp...

  • Article
  • Open Access
1 Citations
1,460 Views
11 Pages

Combined Use of Phenotypic Screening and of a Novel Commercial Assay (REALQUALITY Carba-Screen) for the Rapid Molecular Detection of Carbapenemases: A Single-Center Experience

  • Federica Novazzi,
  • Gabriele Arcari,
  • Francesca Drago Ferrante,
  • Sara Boutahar,
  • Angelo Paolo Genoni,
  • Davide Carcione,
  • Gianluca Cassani,
  • Paolo Gigante,
  • Mattia Carbotti and
  • Nicasio Mancini
  • + 2 authors

Carbapenem resistance is a serious public health threat, causing numerous deaths annually primarily due to healthcare-associated infections. To face this menace, surveillance programs in high-risk patients are becoming a widespread practice. Here we...

  • Article
  • Open Access
6 Citations
4,119 Views
19 Pages

Antimicrobial resistance is a menace to public health on a global scale. In this regard, nanomaterials exhibiting antimicrobial properties represent a promising solution. Both metal and metal oxide nanomaterials are suitable candidates, even though t...

  • Article
  • Open Access
1 Citations
1,741 Views
13 Pages

The emergence of antimicrobial resistance (AMR) in pathogens and their spillover into the environment have become a global public health menace. Insects can acquire these pathogens from the environment and would serve as mechanical and biological vec...

  • Review
  • Open Access
10 Citations
4,123 Views
21 Pages

Meeting at the Crossroad between Obesity and Hepatic Carcinogenesis: Unique Pathophysiological Pathways Raise Expectations for Innovative Therapeutic Approaches

  • Konstantinos Arvanitakis,
  • Stavros P. Papadakos,
  • Vasileios Lekakis,
  • Theocharis Koufakis,
  • Ioannis G. Lempesis,
  • Eleni Papantoniou,
  • Georgios Kalopitas,
  • Vasiliki E. Georgakopoulou,
  • Ioanna E. Stergiou and
  • Georgios Germanidis
  • + 1 author

28 September 2023

The escalating global prevalence of obesity and its intricate association with the development of hepatocellular carcinoma (HCC) pose a substantial challenge to public health. Obesity, acknowledged as a pervasive epidemic, is linked to an array of ch...

  • Article
  • Open Access
68 Citations
13,016 Views
13 Pages

Antibiotic Resistance in an Indian Rural Community: A ‘One-Health’ Observational Study on Commensal Coliform from Humans, Animals, and Water

  • Manju Raj Purohit,
  • Salesh Chandran,
  • Harshada Shah,
  • Vishal Diwan,
  • Ashok J. Tamhankar and
  • Cecilia Stålsby Lundborg

Antibiotic-resistant bacteria are an escalating grim menace to global public health. Our aim is to phenotype and genotype antibiotic-resistant commensal Escherichia coli (E. coli) from humans, animals, and water from the same community with a ‘one-he...

  • Review
  • Open Access
33 Citations
7,041 Views
38 Pages

Pulling the Brakes on Fast and Furious Multiple Drug-Resistant (MDR) Bacteria

  • Abid Ali Khan,
  • Khanzadi Nazneen Manzoor,
  • Aamir Sultan,
  • Maria Saeed,
  • Mahrukh Rafique,
  • Sameen Noushad,
  • Ayesha Talib,
  • Simone Rentschler and
  • Hans-Peter Deigner

Life-threatening bacterial infections have been managed by antibiotics for years and have significantly improved the wellbeing and lifetime of humans. However, bacteria have always been one step ahead by inactivating the antimicrobial agent chemicall...

  • Review
  • Open Access
18 Citations
5,777 Views
23 Pages

26 December 2024

Monkeypox (mpox) is a viral infection closely related to smallpox, manifesting as a milder febrile rash in affected individuals. Over the past two decades, the incidence of mpox has surged, possibly linked to a declining immunity against the smallpox...

  • Article
  • Open Access
11 Citations
4,024 Views
15 Pages

Discovery of Substituted (2-Aminooxazol-4-yl)Isoxazole-3-carboxylic Acids as Inhibitors of Bacterial Serine Acetyltransferase in the Quest for Novel Potential Antibacterial Adjuvants

  • Joana Magalhães,
  • Nina Franko,
  • Samanta Raboni,
  • Giannamaria Annunziato,
  • Päivi Tammela,
  • Agostino Bruno,
  • Stefano Bettati,
  • Stefano Armao,
  • Costanza Spadini and
  • Gabriele Costantino
  • + 4 authors

23 February 2021

Many bacteria and actinomycetales use L-cysteine biosynthesis to increase their tolerance to antibacterial treatment and establish a long-lasting infection. In turn, this might lead to the onset of antimicrobial resistance that currently represents o...

  • Article
  • Open Access
1 Citations
3,657 Views
13 Pages

Hospitalizations for Suicidal Events: Reiteration Risk—The Experience in the Veneto Region, Italy

  • Silvia Cocchio,
  • Giulia Tremolada,
  • Nicola Cogo,
  • Claudia Cozzolino,
  • Mario Saia,
  • Michele Tonon,
  • Francesca Russo,
  • Patrizia Furlan,
  • Marco Fonzo and
  • Vincenzo Baldo

Suicidality poses a significant public health threat and stands as a leading cause of death and disability. Aside from committed suicides, a substantial portion of suicidal behaviors comprises suicide attempts and suicidal ideation. These events may...

  • Review
  • Open Access
27 Citations
3,562 Views
27 Pages

22 October 2022

Antibiotic resistance in bacteria has remained a serious public health concern, resulting in substantial deaths and morbidity each year. Factors such as mutation and abuse of currently available antibiotics have contributed to the bulk of the menace....

  • Review
  • Open Access
143 Citations
26,455 Views
30 Pages

Rapid Methods for Antimicrobial Resistance Diagnostics

  • Georgia D. Kaprou,
  • Ieva Bergšpica,
  • Elena A. Alexa,
  • Avelino Alvarez-Ordóñez and
  • Miguel Prieto

20 February 2021

Antimicrobial resistance (AMR) is one of the most challenging threats in public health; thus, there is a growing demand for methods and technologies that enable rapid antimicrobial susceptibility testing (AST). The conventional methods and technologi...

  • Systematic Review
  • Open Access
4 Citations
3,930 Views
9 Pages

To Save a Girl-Child, You Must Train a Boy-Child: A Note on Situational Irony

  • Emmanuel O. Amoo,
  • Mercy E. Adebayo,
  • Michael O. Owoeye and
  • Matthew E. Egharevba

Despite numerous initiatives and resources to save and protect the health and sexual rights of girls and women, the persistently high rate of unwanted pregnancy, abortion, and sexual violence in sub-Saharan Africa (SSA) has remain a topical public he...

  • Review
  • Open Access
904 Views
30 Pages

20 November 2025

Aflatoxin B1 (AFB1) is a naturally occurring contaminant pervasively found in agricultural produce, exhibiting extremely high carcinogenicity, teratogenicity and immunotoxicity, thereby constituting a substantial menace to worldwide food security and...

  • Case Report
  • Open Access
1 Citations
1,791 Views
11 Pages

2 August 2024

The pandemic of COVID-19 caused by the SARS-CoV-2 virus is ongoing and a serious menace to global public health. An ocular manifestation is an initial sign of the infection. To date, a comprehensive immune profile of patients with mild COVID-19 has n...

  • Article
  • Open Access
3 Citations
3,036 Views
14 Pages

2 June 2024

The menace of human papillomavirus (HPV) infections among low- and middle-income countries with no access to a free HPV vaccine is a public health concern. HPV is one of the most common sexually transmitted infections (STIs) in Nigeria, while the mos...

  • Review
  • Open Access
23 Citations
9,883 Views
62 Pages

30 December 2021

The COVID-19 Pandemic has punched a devastating blow on the majority of the world’s population. Millions of people have been infected while hundreds of thousands have died of the disease throwing many families into mourning and other psychologi...

  • Article
  • Open Access
1 Citations
5,899 Views
19 Pages

London Street Noises: A Ground-Breaking Field Recording Campaign from 1928

  • John L. Drever,
  • Aysegul Yildirim and
  • Mattia Cobianchi

18 February 2021

In a leading article by Sir Percival Philips in the UK popular newspaper, the Daily Mail, July 16, 1928, came the following headlines: “Millions Lost by Noise – Cities’ Worst Plague – Menace to Nerves and Health – What is Being Done to Stop it”. The...

  • Article
  • Open Access
56 Citations
6,695 Views
11 Pages

Paradigm Shift in Antimicrobial Resistance Pattern of Bacterial Isolates during the COVID-19 Pandemic

  • Vikas Saini,
  • Charu Jain,
  • Narendra Pal Singh,
  • Ahmad Alsulimani,
  • Chhavi Gupta,
  • Sajad Ahmad Dar,
  • Shafiul Haque and
  • Shukla Das

Antimicrobial resistance (AMR) is an emerging public health problem in modern times and the current COVID-19 pandemic has further exaggerated this problem. Due to bacterial co-infection in COVID-19 cases, an irrational consumption of antibiotics has...

  • Review
  • Open Access
16 Citations
15,162 Views
74 Pages

3 April 2025

Listeria monocytogenes is an intracellular, Gram-positive, non-spore-forming, non-encapsulated, facultative anaerobic, rod-shaped, and psychrotrophic food-borne pathogen that causes the infection, listeriosis, thus it attracts great attention followi...

  • Article
  • Open Access
33 Citations
5,852 Views
23 Pages

Distribution, investigation, surveillance and control (DISC) of cholera outbreaks in endemic/non-endemic regions has been a concerted approach towards the management of the causal pathogen. Relevant organization, government, health systems and the pu...

  • Article
  • Open Access
4 Citations
4,838 Views
17 Pages

Multivalent Inactivated Vaccine Protects Chickens from Distinct Clades of Highly Pathogenic Avian Influenza Subtypes H5N1 and H5N8

  • Walid H. Kilany,
  • Marwa Safwat,
  • Mohamed A. Zain El-Abideen,
  • Islam Hisham,
  • Yasmine Moussa,
  • Ahmed Ali and
  • Magdy F. Elkady

19 February 2025

Background/Objective: Highly pathogenic avian influenza (HPAI) H5 subtype remains a significant menace to both the poultry industry and human public health. Biosecurity and mass vaccination of susceptible commercial poultry flocks are crucial to redu...

  • Article
  • Open Access
9 Citations
3,111 Views
12 Pages

29 July 2022

Antibiotic drug resistance has emerged as a major public health threat globally. One of the leading causes of drug resistance is the colonization of microorganisms in biofilm mode. Hence, there is an urgent need to design novel and highly effective b...

  • Review
  • Open Access
26 Citations
4,831 Views
19 Pages

The Potential Role of Exosomes in Child and Adolescent Obesity

  • Ioanna Maligianni,
  • Christos Yapijakis,
  • Flora Bacopoulou and
  • George Chrousos

Child and adolescent obesity constitute one of the greatest contemporary public health menaces. The enduring disproportion between calorie intake and energy consumption, determined by a complex interaction of genetic, epigenetic, and environmental fa...

  • Article
  • Open Access
1 Citations
2,195 Views
16 Pages

3 September 2025

Background/Objectives: Meningococcal disease (MD) remains a significant public health concern worldwide. In Serbia, mandatory immunization against MD with the meningococcal polysaccharide vaccine (MenAC) for high-risk groups and international travele...

  • Article
  • Open Access
28 Citations
6,024 Views
33 Pages

Molecular Docking Simulation Studies Identifies Potential Natural Product Derived-Antiwolbachial Compounds as Filaricides against Onchocerciasis

  • Samuel K. Kwofie,
  • Emmanuel Broni,
  • Faruk U. Yunus,
  • John Nsoh,
  • Dela Adoboe,
  • Whelton A. Miller and
  • Michael D. Wilson

13 November 2021

Onchocerciasis is the leading cause of blindness and severe skin lesions which remain a major public health problem, especially in tropical areas. The widespread use of antibiotics and the long duration required for effective treatment continues to a...