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  • Article
  • Open Access
9 Citations
3,390 Views
9 Pages

Is Ocular Accommodation Influenced by Dynamic Ambient Illumination and Pupil Size?

  • Hanyang Yu,
  • Wentao Li,
  • Ziping Chen,
  • Mengzhen Chen,
  • Junwen Zeng,
  • Xijiang Lin and
  • Feng Zhao

Purpose: We investigated ocular accommodative responses and pupil diameters under different light intensities in order to explore whether changes in light intensity aid effective accommodation function training. Methods:A total of 29 emmetropic and m...

  • Article
  • Open Access
2,263 Views
17 Pages

Too Bright to Focus? Influence of Brightness Illusions and Ambient Light Levels on the Dynamics of Ocular Accommodation

  • Antonio Rodán,
  • Angélica Fernández-López,
  • Jesús Vera,
  • Pedro R. Montoro,
  • Beatriz Redondo and
  • Antonio Prieto

30 September 2025

Can brightness illusions modulate ocular accommodation? Previous studies have shown that brightness illusions can influence pupil size as if caused by actual luminance increases. However, their effects on other ocular responses—such as accommod...

  • Article
  • Open Access
9 Citations
2,425 Views
9 Pages

Effects of 0.01% Atropine Instillation Assessed Using Swept-Source Anterior Segment Optical Coherence Tomography

  • Tadahiro Mitsukawa,
  • Yumi Suzuki,
  • Yosuke Momota,
  • Shun Suzuki and
  • Masakazu Yamada

25 September 2021

In this paper, we assessed the short-term effects of 0.01% atropine eye drops on anterior segment parameters by performing ocular biometry using a swept-source anterior segment optical coherence tomography system (AS-OCT). We recruited 17 healthy vol...

  • Article
  • Open Access
2 Citations
3,934 Views
14 Pages

The Prevalence of Accommodative and Binocular Dysfunctions in Children with Reading Difficulties

  • Ilze Ceple,
  • Aiga Svede,
  • Evita Serpa,
  • Evita Kassaliete,
  • Liva Volberga,
  • Rita Mikelsone,
  • Asnate Berzina,
  • Angelina Ganebnaya,
  • Linda Krauze and
  • Gunta Krumina

25 December 2024

Uncorrected refractive error and unsatisfactory performance on several clinical accommodation and binocular vision tests are more common in children who struggle with reading. The aim of the current study is to explore the prevalence of accommodative...

  • Communication
  • Open Access
2,651 Views
7 Pages

Variations in Lens Thickness Affecting the Anterior Chamber Length and Their Potential Measurement Using a Biometer

  • F. Javier Povedano-Montero,
  • Ricardo Bernardez-Villaboa,
  • Gema Martínez-Florentín,
  • Francisco López-Muñoz and
  • Juan E. Cedrún-Sánchez

7 December 2023

Biometry is a critical aspect of ophthalmology, since it facilitates the measurement of several ocular parameters and aids in the diagnosis of conditions like glaucoma. The advent of the IOLMaster in 1999 marked a pivotal moment in biometry by introd...

  • Article
  • Open Access
3,203 Views
19 Pages

Validation of Binocular Vision and Ocular Surface Assessment Tools in Digital Eye Strain Syndrome: The DESIROUS Study

  • Maria João Barata,
  • Pedro Aguiar,
  • Andrzej Grzybowski,
  • Carla Lança and
  • André Moreira-Rosário

25 April 2025

Background: To understand if binocular vision disorders are associated with Digital Eye Strain Syndrome (DESS), a study protocol is needed to ensure consistency across observational studies. This study aims to test the feasibility of a protocol to as...

  • Review
  • Open Access
4 Citations
6,508 Views
21 Pages

A Review of Digital Eye Strain: Binocular Vision Anomalies, Ocular Surface Changes, and the Need for Objective Assessment

  • Maria João Barata,
  • Pedro Aguiar,
  • Andrzej Grzybowski,
  • André Moreira-Rosário and
  • Carla Lança

5 September 2025

(1) Background: This study investigates the impact of digital device usage on the visual system, with a focus on binocular vision. It also highlights the importance of objective assessment in accurately diagnosing and guiding therapeutic approaches f...

  • Article
  • Open Access
2 Citations
1,854 Views
15 Pages

Exploring Changes in Ocular Aberrations for Different Fixation and Accommodation Stimuli

  • María Mechó-García,
  • Rute J. Macedo-de-Araújo,
  • Paulo Fernandes and
  • José Manuel González-Méijome

20 November 2024

Background: Given the lack of standardization in stimulus types for assessing accommodation, we aimed to evaluate accommodative response (AR) and Zernike coefficients using four different stimuli. Methods: Sixteen healthy subjects aged 22–32 ye...

  • Review
  • Open Access
10 Citations
4,743 Views
14 Pages

7 March 2023

High-order aberrations (HOAs) are optical defects that degrade the image quality. They change with factors such as pupil diameter, age, and accommodation. The changes in optical aberrations during accommodation are mainly due to lens shape and positi...

  • Article
  • Open Access
3 Citations
2,318 Views
10 Pages

24 September 2024

Purpose: Glaucoma medication may accelerate the progression of presbyopia. The aim of this study was to compare presbyopia between controls and patients with glaucoma in their 40s. Methods: This was a cross-sectional study of bilateral phakic partici...

  • Article
  • Open Access
5 Citations
7,483 Views
16 Pages

Pupil Function in Pseudophakia: Proximal Miosis Behavior and Optical Influence

  • Elsa Fonseca,
  • Paulo Fiadeiro,
  • Renato Gomes,
  • Angel Sanchez Trancon,
  • António Baptista and
  • Pedro Serra

6 November 2019

The pseudophakic eye lacks the ability to produce a refractive change in response to object proximity. Thus, individual anatomical features such as the pupil size play an important role in achieving functional vision levels. In this work, the range o...

  • Feature Paper
  • Article
  • Open Access
2 Citations
5,302 Views
11 Pages

More than a century has passed since Allvar Gullstrand proposed his so called “mechanism of intracapsular accommodation” based on the concept that the change in lens power during accommodation can be larger if the lens is modeled by two d...

  • Article
  • Open Access
3 Citations
3,244 Views
9 Pages

19 June 2024

The university population has high visual demands. It is therefore important to assess the prevalence of symptoms in these subjects, which may affect their academic performance. In this cross-sectional study, a randomized sample of 252 subjects from...

  • Case Report
  • Open Access
1 Citations
3,549 Views
7 Pages

Influence of Blood Glycemia Levels in Refraction, Binocular Vision and Accommodation: A Case Report

  • Marc Argilés,
  • Jessica Sala-Oller,
  • Bernat Sunyer-Grau,
  • Cristina Rovira-Gay and
  • Luis Pérez-Mañá

23 March 2024

This case report provides us with insight on how blood glycemia affects refraction, vergence and accommodation in a single diabetic patient. A 21-year-old type I diabetic woman was the subject studied in this report. Refraction, near and far fusional...

  • Review
  • Open Access
256 Views
12 Pages

19 February 2026

Background: Chronic work-related stress, including exposure to mobbing, is associated with a wide range of psychological and somatic consequences. However, its potential impact on visual function, particularly in the absence of structural ocular dama...

  • Article
  • Open Access
12 Citations
5,223 Views
14 Pages

Factors Influencing Pseudo-Accommodation—The Difference between Subjectively Reported Range of Clear Focus and Objectively Measured Accommodation Range

  • Sandeep K. Dhallu,
  • Amy L. Sheppard,
  • Tom Drew,
  • Toshifumi Mihashi,
  • Juan F. Zapata-Díaz,
  • Hema Radhakrishnan,
  • D. Robert Iskander and
  • James S. Wolffsohn

28 June 2019

The key determinants of the range of clear focus in pre-presbyopes and their relative contributions to the difference between subjective range of focus and objective accommodation assessments have not been previously quantified. Fifty participants (a...

  • Article
  • Open Access
8 Citations
4,588 Views
13 Pages

The Effect of Accommodation on Peripheral Refraction under Two Illumination Conditions

  • Raquel van Ginkel,
  • María Mechó,
  • Genis Cardona and
  • José M. González-Méijome

The clinical importance of peripheral refraction as a function of accommodation has become increasingly evident in the last years with special attention given to myopia control. Low order ocular aberrations were measured with a Hartmann–Shack a...

  • Article
  • Open Access
1 Citations
1,739 Views
11 Pages

9 October 2024

This study investigated the relationship between high-order aberrations (HOAs) and accommodative dysfunctions by analyzing their changes with accommodation. Understanding this relationship is important for understanding the mechanisms underlying thes...

  • Feature Paper
  • Article
  • Open Access
4 Citations
4,184 Views
15 Pages

3 January 2022

This pseudo-experimental, prospective, and longitudinal pilot study was conducted to characterize the optical and visual changes occurring in the short-term wear of a hydrophilic contact lens (CL) based on extended focus technology (EDOF). A total of...

  • Article
  • Open Access
2 Citations
3,925 Views
12 Pages

Parafoveal and Perifoveal Accommodation Response to Defocus Changes Induced by a Tunable Lens

  • Najnin Sharmin,
  • Petros Papadogiannis,
  • Dmitry Romashchenko,
  • Linda Lundström and
  • Brian Vohnsen

27 July 2023

The accommodative response of the human eye is predominantly driven by foveal vision, but reacts also to off-foveal stimuli. Here, we report on monocular accommodation measurements using parafoveal and perifoveal annular stimuli centered around the f...

  • Article
  • Open Access
7 Citations
5,261 Views
11 Pages

Cognitive Demand and Accommodative Microfluctuations

  • Niall J. Hynes,
  • Matthew P. Cufflin,
  • Karen M. Hampson and
  • Edward A. H. Mallen

6 September 2018

Previous studies have shown cognition to have an influence on accommodation. Temporal variation in the accommodative response occurs during the fixation on a stationary target. This constantly shifting response has been called accommodative micro-flu...

  • Case Report
  • Open Access
6,635 Views
10 Pages

Visual Rehabilitation in Post Mild Traumatic Brain Injury. Case-Based Review

  • Carmen López-de-la-Fuente,
  • Hermes Barriga-Longás and
  • Elvira Orduna-Hospital

Background: Traumatic brain injury (TBI) can cause visual dysfunction affecting binocularity, spatial orientation, posture, and balance. Currently, there are several options for treating manifested visual disturbances; vision therapy is one of the po...

  • Review
  • Open Access
53 Citations
23,123 Views
24 Pages

14 January 2022

The autonomic nervous system (ANS) confers neural control of the entire body, mainly through the sympathetic and parasympathetic nerves. Several studies have observed that the physiological functions of the eye (pupil size, lens accommodation, ocular...

  • Article
  • Open Access
4 Citations
2,845 Views
9 Pages

Changes in Accommodative and Binocular Function following Phakic Intraocular Lens for High and Low-to-Moderate Myopia

  • Esther López-Artero,
  • Francisco Poyales,
  • Nuria Garzón,
  • Alicia Matamoros,
  • Alba Sáez,
  • Ying Zhou and
  • María García-Montero

The aim was to evaluate accommodative and binocular function of phakic intraocular lens implantable collamer lens (ICL) in high and low-to-moderate myopia. Prospective comparative cohort study with 38 myopic patients who underwent ICL implantation we...

  • Article
  • Open Access
23 Citations
1,922 Views
31 Pages

Eye Movements in Mild Traumatic Brain Injury: Ocular Biomarkers

  • Matthew A. McDonald,
  • Samantha J. Holdsworth and
  • Helen V. Danesh-Meyer

Mild traumatic brain injury (mTBI, or concussion), results from direct and indirect trauma to the head (i.e. a closed injury of transmitted forces), with or without loss of consciousness. The current method of diagnosis is largely based on symptom as...

  • Review
  • Open Access
22 Citations
7,974 Views
34 Pages

Nutraceuticals: A Promising Therapeutic Approach in Ophthalmology

  • Carlos Rodrigo Castro-Castaneda,
  • Francisco Altamirano-Lamarque,
  • Alan Gabriel Ortega-Macías,
  • Francisco J. Santa Cruz-Pavlovich,
  • Alejandro Gonzalez-De la Rosa,
  • Juan Armendariz-Borunda,
  • Arturo Santos and
  • Jose Navarro-Partida

25 November 2022

Oxidative stress represents one of the main factors driving the pathophysiology of multiple ophthalmic conditions including presbyopia, cataracts, dry eye disease (DED), glaucoma, age-related macular degeneration (AMD) and diabetic retinopathy (DR)....

  • Article
  • Open Access
4 Citations
3,888 Views
13 Pages

16 October 2019

Volumetric display shows promising implications for healthcare related applications as an innovative technology that creates real three-dimensional (3D) image by illuminating points in three-dimensional space to generate volumetric images without ima...

  • Review
  • Open Access
22 Citations
19,394 Views
16 Pages

Pseudomyopia: A Review

  • María García-Montero,
  • Gema Felipe-Márquez,
  • Pedro Arriola-Villalobos and
  • Nuria Garzón

4 March 2022

This review has identified evidence about pseudomyopia as the result of an increase in ocular refractive power due to an overstimulation of the eye’s accommodative mechanism. It cannot be confused with the term “secondary myopia”, w...

  • Article
  • Open Access
7 Citations
2,840 Views
12 Pages

Tweenager Computer Visual Syndrome Due to Tablets and Laptops during the Postlockdown COVID-19 Pandemic and the Influence on the Binocular and Accommodative System

  • Concepción De-Hita-Cantalejo,
  • José-María Sánchez-González,
  • Carmen Silva-Viguera and
  • María Carmen Sánchez-González

9 September 2022

The aim of our study was to compare computer visual syndrome (CVS) in a tweenager student population who use tablets and laptops only to play versus CVS in tweenagers who use these digital devices at school to study, in addition to playing. The tests...

  • Article
  • Open Access
1 Citations
1,006 Views
11 Pages

A Novel Virtual Reality-Based System for Measuring Deviation Angle in Strabismus: A Prospective Study

  • Jhih-Yi Lu,
  • Yin-Cheng Liu,
  • Jui-Bang Lu,
  • Ming-Han Tsai,
  • Wen-Ling Liao,
  • I-Ming Wang,
  • Hui-Ju Lin and
  • Yu-Te Huang

20 September 2025

Background/Objectives: To develop a new Virtual Reality (VR) system software for measuring ocular deviation in strabismus patients. Methods: This prospective study included subjects with basic-type exotropia (XT) and non-refractive accommodative esot...

  • Review
  • Open Access
4,347 Views
20 Pages

The Clinical Usefulness of Evaluating the Lens and Intraocular Lenses Using Optical Coherence Tomography: An Updated Literature Review

  • José Ignacio Fernández-Vigo,
  • Lucía De-Pablo-Gómez-de-Liaño,
  • Ignacio Almorín-Fernández-Vigo,
  • Beatriz De-Pablo-Gómez-de-Liaño,
  • Ana Macarro-Merino,
  • Julián García-Feijóo and
  • José Ángel Fernández-Vigo

22 November 2024

The Lens Dysfunction Syndrome includes two widespread ocular disorders: presbyopia and cataract. Understanding its etiology, onset, progression, impact, prevention, and treatment remains a significant scientific challenge. The lens is a fundamental s...

  • Article
  • Open Access
13 Citations
3,846 Views
18 Pages

Mechanical Load and Piezo1 Channel Regulated Myosin II Activity in Mouse Lenses

  • Ariana Allen,
  • Rupalatha Maddala,
  • Camelia Eldawy and
  • Ponugoti Vasantha Rao

The cytoarchitecture and tensile characteristics of ocular lenses play a crucial role in maintaining their transparency and deformability, respectively, which are properties required for the light focusing function of ocular lens. Calcium-dependent m...

  • Feature Paper
  • Review
  • Open Access
2 Citations
1,444 Views
12 Pages

Combined Cataract and Vitrectomy Surgery in Pediatric Patients

  • Armando J. Ruiz-Justiz,
  • Vanessa Cruz-Villegas,
  • Stephen G. Schwartz,
  • Victor M. Villegas and
  • Timothy G. Murray

29 June 2025

Purpose: To review the current literature on the combined use of cataract surgery (or lensectomy) and vitrectomy in pediatric patients, with a focus on clinical indications, surgical techniques, outcomes, and complications across various pediatric oc...

  • Article
  • Open Access
2 Citations
1,296 Views
10 Pages

Effect of Small Angle Misalignments on Ocular Wavefront Zernike Coefficients

  • Ebrahim Safarian Baloujeh,
  • Francisco J. Ávila and
  • José M. González-Méijome

27 August 2024

Purpose: To assess the possible impact of minor changes in fixation on wavefront measurements as a potential constraint in detecting subtle temporal variations in ocular wavefront error. Methods: Twelve healthy subjects with an average age of 36.3 &p...

  • Article
  • Open Access
2 Citations
1,646 Views
12 Pages

29 March 2024

Background: Determination of the number of pupils at risk of developing pre-myopia and selected ophthalmic parameters in a group of 1155 children aged 8. Material: Ophthalmic examinations were performed in Polish 8-year-old, /1518 individuals/; 1155...

  • Case Report
  • Open Access
188 Views
6 Pages

The Key Role of the Ophthalmologist in Diagnosing Botulism: Two Case Reports

  • Larisa Cujba,
  • Ovidiu Samoila,
  • Silvina Ilut,
  • Vitalie Vacaras and
  • Cristina Stan

31 December 2022

Introduction: Botulinum toxin, the strongest known neurotoxin, is the cause of a rare fatal neuroparalytic disease characterized by the so-called “four Ds”: diplopia, dysarthria, dysphagia, dry mouth. If left untreated, botulism may cause paralysis o...

  • Article
  • Open Access
12 Citations
3,529 Views
11 Pages

15 November 2021

Taiwan is commonly noted for its high prevalence of myopia, as well as a long history of more than 20 years of using atropine to control myopia. However, the clinical implications are rarely discussed. This is a cross-sectional study investigating th...

  • Article
  • Open Access
33 Citations
3,991 Views
21 Pages

Insight into the Taxonomic Resolution of the Pleosporalean Species Associated with Dead Woody Litter in Natural Forests from Yunnan, China

  • Dhanushka N. Wanasinghe,
  • Guang-Cong Ren,
  • Jian-Chu Xu,
  • Ratchadawan Cheewangkoon and
  • Peter E. Mortimer

6 April 2022

In the course of investigating the systematics of woody litter micromycete associates in Yunnan Province, China, we found one new species in Phaeoseptaceae, one new genus and three new species in Sulcatisporaceae from 16 specimens collected (ten coll...

  • Article
  • Open Access
6 Citations
5,062 Views
10 Pages

Improving Visual Comfort during Computer Gaming with Preservative-Free Hyaluronic Acid Artificial Tears Added to Ergophthalmological Measures

  • Fernando Trancoso Vaz,
  • Ester Fernández-López,
  • María José Roig-Revert,
  • Alicia Martín and
  • Cristina Peris-Martínez

11 January 2023

Digital asthenopia (DA) or Computer Vision Syndrome can occur after prolonged use of digital devices and is usually managed with ergophthalmological measures and the use of artificial tears. This prospective, controlled study evaluated the use of hya...

  • Article
  • Open Access
2,772 Views
14 Pages

Refractive Astigmatism Consistency Pre- and Post-Cycloplegia in Pediatric Population

  • Agustin Peñaranda,
  • Oscar Torrado,
  • Ana Márquez,
  • António M. Baptista and
  • Pedro M. Serra

Background: Cycloplegic refraction is crucial in pediatric eye assessments. While spherical refraction changes due to cycloplegia are well-documented, astigmatic alterations remain unclear. This study assessed the agreement between spherical and asti...

  • Article
  • Open Access
5 Citations
3,179 Views
12 Pages

Novel Application of Long Short-Term Memory Network for 3D to 2D Retinal Vessel Segmentation in Adaptive Optics—Optical Coherence Tomography Volumes

  • Christopher T. Le,
  • Dongyi Wang,
  • Ricardo Villanueva,
  • Zhuolin Liu,
  • Daniel X. Hammer,
  • Yang Tao and
  • Osamah J. Saeedi

12 October 2021

Adaptive optics—optical coherence tomography (AO-OCT) is a non-invasive technique for imaging retinal vascular and structural features at cellular-level resolution. Whereas retinal blood vessel density is an important biomarker for ocular diseases, p...

  • Article
  • Open Access
3 Citations
1,519 Views
13 Pages

Wavefront Changes during a Sustained Reading Task in Presbyopic Eyes

  • Ebrahim Safarian Baloujeh and
  • José M. González-Méijome

14 June 2024

The objective of this study was to assess the effect of sustained reading on the temporal changes in the wavefront error in the presbyopic eye. The wavefront aberration of the eyes was measured using an IRX3 Shack–Hartmann aberrometer before an...

  • Article
  • Open Access
5 Citations
2,213 Views
20 Pages

Phylogenetic Insights Reveal New Taxa in Thyridariaceae and Massarinaceae

  • Wen-Hui Tian,
  • Yan Jin,
  • Yue-Chi Liao,
  • Turki KH. Faraj,
  • Xin-Yong Guo and
  • Sajeewa S. N. Maharachchikumbura

2 August 2024

Pleosporales is a highly diverse (and the largest) order in Dothideomycetes, and it is widespread in decaying plants in various environments around the world. During a survey of fungal diversity in Sichuan Province, China, specimens of hyphomycetous...

  • Article
  • Open Access
2 Citations
1,515 Views
13 Pages

8 November 2024

Background: Bradykinin is an endogenously produced nonapeptide with many physiological and pathological functions that are mediated by two pharmacologically defined receptor subtypes, B1- and B2-receptors. Current studies sought to characterize the f...