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3,708 Results Found

  • Article
  • Open Access
28 Citations
4,401 Views
11 Pages

Prognostic Value of Malondialdehyde (MDA) in the Temporal Progression of Chronic Spinal Cord Injury

  • Sergio Haro Girón,
  • Jorge Monserrat Sanz,
  • Miguel A. Ortega,
  • Cielo Garcia-Montero,
  • Oscar Fraile-Martínez,
  • Ana M. Gómez-Lahoz,
  • Diego Liviu Boaru,
  • Diego de Leon-Oliva,
  • Luis G. Guijarro and
  • Melchor Álvarez-Mon
  • + 2 authors

2 April 2023

Background: Oxidative stress is a major signature of spinal cord injury (SCI). The altered levels of various oxidative stress markers have been demonstrated in acute and chronic SCI. However, the variation of these markers in patients with chronic SC...

  • Article
  • Open Access
5 Citations
2,794 Views
9 Pages

29 May 2022

Trichloroethylene (TCE) is commonly used in various industries. If wastewater in factories is not effectively treated, the inflow into and subsequent contamination of underground water is likely. Our study assessed the association of exposure to TCE...

  • Article
  • Open Access
25 Citations
6,543 Views
14 Pages

An Improved GC-MS Method for Malondialdehyde (MDA) Detection: Avoiding the Effects of Nitrite in Foods

  • Wenjie Wang,
  • Zhiwen Zhang,
  • Xiaoying Liu,
  • Xiaoji Cao,
  • Lianzhu Wang,
  • Yuting Ding and
  • Xuxia Zhou

19 April 2022

Malondialdehyde (MDA) is one of the representative end products under lipid peroxidation, indicating the degree of lipid oxidation in foods. However, compounds in pickled products, especially the nitrite in salted lean pork can react with MDA under t...

  • Systematic Review
  • Open Access
58 Citations
8,301 Views
16 Pages

Urinary Malondialdehyde (MDA) Concentrations in the General Population—A Systematic Literature Review and Meta-Analysis

  • Antonio Toto,
  • Pascal Wild,
  • Mélanie Graille,
  • Veronica Turcu,
  • Camille Crézé,
  • Maud Hemmendinger,
  • Jean-Jacques Sauvain,
  • Enrico Bergamaschi,
  • Irina Guseva Canu and
  • Nancy B. Hopf

29 March 2022

Oxidative stress has been associated with various inflammation-related human diseases. It is defined as an imbalance between the production and elimination of reactive oxygen species (ROS). ROS can oxidize proteins, lipids, and DNA, and some of these...

  • Article
  • Open Access
5 Citations
1,839 Views
14 Pages

A systematic theoretical study was conducted on the triel bonds (TrB) within the BH3∙∙∙M(MDA)2 and C5H4BX∙∙∙M(MDA)2 (M = Ni, Pd, Pt, X = H, CN, F, CH3, NH2, MDA = enolated malondialdehyde) complexes, with BH3 and C...

  • Article
  • Open Access
6 Citations
3,218 Views
12 Pages

The simultaneous detection of atherosclerotic cardiovascular disease (ACSVD) biomarkers was recently of great scientific interest. In this work, magnetic beads-based immunosensors for the simultaneous detection of low density lipoprotein (LDL) and ma...

  • Systematic Review
  • Open Access
7 Citations
2,381 Views
16 Pages

Increased Blood Concentrations of Malondialdehyde in Plasmodium Infection: A Systematic Review and Meta-Analysis

  • Onchuma Mueangson,
  • Aongart Mahittikorn,
  • Nsoh Godwin Anabire,
  • Wanida Mala and
  • Manas Kotepui

Several studies have evaluated the relationship between malondialdehyde (MDA) concentrations and Plasmodium infections; however, the findings remain inconclusive. This study synthesized differences in MDA concentrations among patients with different...

  • Article
  • Open Access
3 Citations
2,500 Views
12 Pages

Association of Plasma Carotenoid and Malondialdehyde Levels with Physical Performance in Korean Adolescents

  • Heeyeon Joo,
  • Jiyoung Hwang,
  • Ji Yeon Kim,
  • Saejong Park,
  • Hyesook Kim and
  • Oran Kwon

Increased oxidative stress has been shown to lead to muscle damage and reduced physical performance. The antioxidant mechanism is most likely to reduce these relationships, but in the context of the action of carotenoids, more research is needed. Thi...

  • Article
  • Open Access
16 Citations
4,390 Views
19 Pages

Reactive Dicarbonyl Scavenging Effectively Reduces MPO-Mediated Oxidation of HDL and Restores PON1 Activity

  • Jiansheng Huang,
  • Patricia G. Yancey,
  • Huan Tao,
  • Mark S. Borja,
  • Loren E. Smith,
  • Valentina Kon,
  • Sean S. Davies and
  • MacRae F. Linton

30 June 2020

Atheroprotective functions of high-density lipoproteins (HDL) are related to the activity of HDL-associated enzymes such as paraoxonase 1 (PON1). We examined the impact of inhibition of myeloperoxidase (MPO)-mediated HDL oxidation by PON1 on HDL malo...

  • Communication
  • Open Access
5 Citations
1,781 Views
10 Pages

Clearance and Utilization of Dicarbonyl-Modified LDL in Monkeys and Humans

  • Vadim Z. Lankin,
  • Galina G. Konovalova,
  • Sergey P. Domogatsky,
  • Alla K. Tikhaze,
  • Igor N. Klots and
  • Marat V. Ezhov

The kinetics of elimination of various dicarbonyl-modified low-density lipoproteins from the bloodstream of Macaca mulatta monkeys were investigated. The low-density lipoproteins (LDL) in the monkey blood plasma were isolated by density gradient ultr...

  • Review
  • Open Access
17 Citations
6,423 Views
20 Pages

(1) Background: Malondialdehyde (MDA) is a major and stable product of oxidative stress. MDA circulates in the blood and is excreted in the urine in its free and conjugated forms, notably with L-lysine and L-serine. MDA is the most frequently measure...

  • Article
  • Open Access
4,518 Views
17 Pages

1 October 2024

Background: The function of olive oil polyphenols in suppressing the oxidation of low-density lipoprotein (LDL) is well-known in Europeans. However, it remains unclear whether olive oil polyphenols exert antioxidant effects in Japanese people. Object...

  • Article
  • Open Access
8 Citations
2,767 Views
12 Pages

Hormonal changes associated with pregnancy promote oral bacterial growth, which may affect salivary nitric oxide (NO) levels, oxidative stress (OS), and antioxidant capacity (AC). We hypothesized that caries-related bacterial load, NO level, and OS i...

  • Article
  • Open Access
2 Citations
2,919 Views
16 Pages

23 February 2022

We evaluated the growth potential of three minor fruit species (Grewia asiatica L., Syzgium cummini and Tamarindus indica L.) after exposure to increasing Ni levels (0, 10, 20 and 40 µg kg−1 soil). The growth attributes, lipid peroxidatio...

  • Article
  • Open Access
69 Citations
6,841 Views
17 Pages

10 November 2022

Some physiological, oxidative, and antioxidant enzymatic patterns were assessed in plants of three local Sicilian landraces of long shelf-life tomatoes (‘Custonaci’, ‘Salina’, and ‘Vulcano’), as compared to the com...

  • Article
  • Open Access
1 Citations
2,974 Views
13 Pages

Background: The association between the biomarkers of environmental exposure, oxidative stress, and health-related behaviors in community residents living in an endemic viral hepatitis area and near petrochemical industrial complexes remains unclear....

  • Article
  • Open Access
15 Citations
2,320 Views
21 Pages

Strawberry and Drupe Fruit Wines Antioxidant Activity and Protective Effect Against Induced Oxidative Stress in Rat Synaptosomes

  • Uroš Čakar,
  • Mirjana Čolović,
  • Danijela Milenković,
  • Maja Pagnacco,
  • Jelena Maksimović,
  • Danijela Krstić and
  • Brižita Đorđević

28 January 2025

The aim of this study was to investigate the antioxidant capacity of fruit wines and their protective effects against hydrogen peroxide-induced oxidative stress in rat synaptosomes in vitro. The wines were produced from strawberries and drupe fruits...

  • Article
  • Open Access
4 Citations
2,353 Views
16 Pages

Biochemical and Physiological Responses of Weeds to the Application of a Botanical Herbicide Based on Cinnamon Essential Oil

  • Sofiene Ben Kaab,
  • Juan Antonio Fernández Pierna,
  • Berenice Foncoux,
  • Philippe Compère,
  • Vincent Baeten and
  • M. Haïssam Jijakli

6 December 2024

The use of chemical herbicides induces negative impacts on the environment, animals, and human health. It also leads to the development of herbicide-resistant weeds. In this context, natural and efficacious herbicides are highly sought after. Essenti...

  • Article
  • Open Access
15 Citations
2,891 Views
12 Pages

Biomarkers of Oxidative Stress in Systemic Lupus Erythematosus Patients with Active Nephritis

  • Lu Liu,
  • Karina de Leeuw,
  • Suzanne Arends,
  • Berber Doornbos-van der Meer,
  • Marian L. C. Bulthuis,
  • Harry van Goor and
  • Johanna Westra

17 August 2023

Oxidative stress plays an important role in systemic lupus erythematosus (SLE) and especially in lupus nephritis (LN). The aim of this study was to compare redox-related biomarkers between patients with active LN, quiescent SLE (Q-SLE) and healthy co...

  • Article
  • Open Access
7 Citations
4,033 Views
17 Pages

Effects of Dietary Supplementation of Salvia officinalis L. in Organic Laying Hens on Egg Quality, Yolk Oxidative Stability and Eggshell Microbiological Counts

  • Dimitrios Galamatis,
  • Georgios A. Papadopoulos,
  • Diamanto Lazari,
  • Dimitrios Fletouris,
  • Evanthia Petridou,
  • Georgios I. Arsenos and
  • Paschalis Fortomaris

26 August 2021

Aromatic plants of Labiatae family are used in poultry diets because of their antimicrobial and antioxidant activity. The notion is that hens raised in organic systems face several health and environmental challenges. Hence, the objective here was to...

  • Article
  • Open Access
43 Citations
5,189 Views
15 Pages

Effects of Hot Air Treatments on Postharvest Storage of Newhall Navel Orange

  • Chunpeng Wan,
  • İbrahim Kahramanoğlu,
  • Jinyin Chen,
  • Zengyu Gan and
  • Chuying Chen

1 February 2020

The effects of hot air flow (HAF) treatment on the postharvest storage of ‘Newhall’ navel oranges were investigated in this study. Studies were conducted with two separate sections. First of all, the effects of HAF at 37 °C for 36 h,...

  • Article
  • Open Access
21 Citations
6,322 Views
9 Pages

Comparative Effect of Bergamot Polyphenolic Fraction and Red Yeast Rice Extract in Rats Fed a Hyperlipidemic Diet: Role of Antioxidant Properties and PCSK9 Expression

  • Rocco Mollace,
  • Roberta Macrì,
  • Annamaria Tavernese,
  • Micaela Gliozzi,
  • Vincenzo Musolino,
  • Cristina Carresi,
  • Jessica Maiuolo,
  • Massimo Fini,
  • Maurizio Volterrani and
  • Vincenzo Mollace

22 January 2022

Elevated serum cholesterol levels, either associated or not with increased triglycerides, represent a risk of developing vascular injury, mostly leading to atherothrombosis-related diseases including myocardial infarction and stroke. Natural products...

  • Article
  • Open Access
1,683 Views
13 Pages

5-Hydroxymethylfurfural: A Particularly Harmful Molecule Inducing Toxic Lipids and Proteins?

  • Joachim Greilberger,
  • Georg Feigl,
  • Matthias Greilberger,
  • Simona Bystrianska and
  • Michaela Greilberger

26 September 2025

Introduction: 5-HMF is a molecule found in carbohydrate-rich foods that is associated not only with cancer and anaphylactic reactions, but also with anti-oxidant properties. Questions arose as to whether 5-HMF exhibited a catalytic effect in relation...

  • Article
  • Open Access
1 Citations
2,127 Views
12 Pages

Effect of Etanercept on Plasmodium yoelii MDR-Induced Liver Lipid Infiltration

  • Bhavana Singh Chauhan,
  • Sarika Gunjan,
  • Sunil Kumar Singh,
  • Swaroop Kumar Pandey and
  • Renu Tripathi

The lipid is a vital metabolic and structural component of the malaria parasite. Malaria parasite-induced liver lipid deposits undergo peroxidation, which ultimately causes tissue damage and histopathological changes, which further lead to many compl...

  • Article
  • Open Access
5 Citations
2,425 Views
17 Pages

16 July 2023

Waste cement, a common by-product of urban construction, is often wasted in huge quantities and is worthless. However, some studies have confirmed that waste cement can be used as an alternative heavy metal immobilizing agent. Waste cements, derived...

  • Article
  • Open Access
5 Citations
2,834 Views
19 Pages

Allelopathy, a biological phenomenon where plants release chemicals that influence the growth and development of neighboring flora, offers potential natural alternatives for weed management in agriculture. This study investigated the allelopathic eff...

  • Article
  • Open Access
28 Citations
5,136 Views
13 Pages

Flavonoids: Antiplatelet Effect as Inhibitors of COX-1

  • Cristina Zaragozá,
  • Miguel Ángel Álvarez-Mon,
  • Francisco Zaragozá and
  • Lucinda Villaescusa

8 February 2022

Flavonoids are compounds with a benzopyranic structure that exhibits multiple pharmacological activities. They are known for their venotonic activity, but their mechanism of action remains unclear. It is thought that, as this mechanism is mediated by...

  • Article
  • Open Access
12 Citations
4,192 Views
13 Pages

The Effect of Molecular Hydrogen on Functional States of Erythrocytes in Rats with Simulated Chronic Heart Failure

  • Anna Vyacheslavovna Deryugina,
  • Darya Andreevna Danilova,
  • Vladimir Viktorovich Pichugin and
  • Yurii Dmitrievich Brichkin

2 February 2023

Molecular hydrogen has an anti-inflammatory and cardioprotective effect, which is associated with its antioxidant properties. Erythrocytes are subjected to oxidative stress in pathologies of the cardiovascular system, which is the cause of a violatio...

  • Article
  • Open Access
2 Citations
4,205 Views
26 Pages

The involvement of stress ethylene in early chilling injury (CI) symptom development of mature-green (MG) banana fruit was examined using the ethylene action inhibitor, 1-methyclopropene (1-MCP). MG banana fruit pretreated with 0 or 50 μg L−...

  • Article
  • Open Access
845 Views
12 Pages

20 February 2025

Soil salinity is a pervasive challenge in agricultural regions, significantly impacting plant growth and productivity. Addressing the adverse implications of soil salinization and capitalizing on organic waste resources has the potential to yield sub...

  • Article
  • Open Access
29 Citations
4,947 Views
15 Pages

Protective Effect of Antioxidants in Nitric Oxide/COX-2 Interaction during Inflammatory Pain: The Role of Nitration

  • Sara Ilari,
  • Concetta Dagostino,
  • Valentina Malafoglia,
  • Filomena Lauro,
  • Luigino Antonio Giancotti,
  • Antonella Spila,
  • Stefania Proietti,
  • Domenica Ventrice,
  • Milena Rizzo and
  • Carolina Muscoli
  • + 4 authors

16 December 2020

In clinical practice, inflammatory pain is an important, unresolved health problem, despite the utilization of non-steroidal anti-inflammatory drugs (NSAIDs). In the last decade, different studies have proven that reactive oxygen species (ROS) and re...

  • Article
  • Open Access
20 Citations
4,035 Views
18 Pages

Phytotoxic Activity of Alkaloids in the Desert Plant Sophora alopecuroides

  • Lijing Lei,
  • Yu Zhao,
  • Kai Shi,
  • Ying Liu,
  • Yunxia Hu and
  • Hua Shao

6 October 2021

Sophora alopecuroides is known to produce relatively large amounts of alkaloids; however, their ecological consequences remain unclear. In this study, we evaluated the allelopathic potential of the main alkaloids, including aloperine, matrine, oxymat...

  • Review
  • Open Access
936 Views
38 Pages

The Redox–Adhesion–Exosome (RAX) Hub in Cancer: Lipid Peroxidation-Driven EMT Plasticity and Ferroptosis Defense with HNE/MDA Signaling and Lipidomic Perspectives

  • Moon Nyeo Park,
  • Jinwon Choi,
  • Rosy Iara Maciel de Azambuja Ribeiro,
  • Domenico V. Delfino,
  • Seong-Gyu Ko and
  • Bonglee Kim

8 December 2025

Cancer cell plasticity drives metastasis and therapy resistance through dynamic transitions between epithelial, mesenchymal, and neural crest stem-like (NCSC) states; however, a unifying mechanism that stabilizes these transitions remains undefined....

  • Article
  • Open Access
50 Citations
7,453 Views
17 Pages

Liposomal Curcumin is Better than Curcumin to Alleviate Complications in Experimental Diabetic Mellitus

  • Adriana Elena Bulboacă,
  • Alina S. Porfire,
  • Lucia R. Tefas,
  • Paul Mihai Boarescu,
  • Sorana D. Bolboacă,
  • Ioana C. Stănescu,
  • Angelo Corneliu Bulboacă and
  • Gabriela Dogaru

27 February 2019

Curcumin (CC) is known to have anti-inflammatory and anti-oxidative properties and has already been tested for its efficiency in different diseases including diabetes mellitus (DM). New formulations and route administration were designed to obtain pr...

  • Article
  • Open Access
2 Citations
3,080 Views
9 Pages

2 March 2020

During cold storage, packed red blood cells (PRBCs) undergo slow detrimental changes that are collectively termed storage lesion. The aging of the cells causes alterations in the composition of the storage-medium in the PRBC unit. In this paper, we p...

  • Article
  • Open Access
33 Citations
10,431 Views
15 Pages

The Effects of Tocotrienol-Rich Vitamin E (Tocovid) on Diabetic Neuropathy: A Phase II Randomized Controlled Trial

  • Yeek Tat Ng,
  • Sonia Chew Wen Phang,
  • Gerald Chen Jie Tan,
  • En Yng Ng,
  • Nevein Philip Botross Henien,
  • Uma Devi M. Palanisamy,
  • Badariah Ahmad and
  • Khalid Abdul Kadir

23 May 2020

Chronic hyperglycemia increases oxidative stress, activates inflammatory pathways and reduces nerve growth factor (NGF) among diabetic patients, which contribute to development of diabetic peripheral neuropathy (DPN). Tocotrienol-Rich Vitamin E (Toco...

  • Article
  • Open Access
25 Citations
3,607 Views
9 Pages

Oxidant/Antioxidant Status of Breast Cancer Patients in Pre- and Post-Operative Periods

  • Janina Didžiapetrienė,
  • Birutė Kazbarienė,
  • Renatas Tikuišis,
  • Audrius Dulskas,
  • Daiva Dabkevičienė,
  • Vaida Lukosevičienė,
  • Eglė Kontrimavičiūtė,
  • Kęstutis Sužiedėlis and
  • Valerijus Ostapenko

11 February 2020

Background and Objectives: The purpose of this study is to evaluate the level of oxidative stress before and after breast cancer surgery. Materials and Methods: Malondialdehyde (MDA) level was tested using a thiobarbituric acid (TBA) assay based on t...

  • Systematic Review
  • Open Access
21 Citations
3,534 Views
18 Pages

Circulating Malondialdehyde Concentrations in Obstructive Sleep Apnea (OSA): A Systematic Review and Meta-Analysis with Meta-Regression

  • Maria Carmina Pau,
  • Elisabetta Zinellu,
  • Sara S. Fois,
  • Barbara Piras,
  • Gianfranco Pintus,
  • Ciriaco Carru,
  • Arduino A. Mangoni,
  • Alessandro G. Fois,
  • Angelo Zinellu and
  • Pietro Pirina

Oxidative stress induced by nocturnal intermittent hypoxia plays a significant pathophysiological role in obstructive sleep apnea (OSA). Malondialdehyde (MDA), one of the most commonly investigated markers of lipid peroxidation, might assist with the...

  • Article
  • Open Access
9 Citations
2,794 Views
16 Pages

30 September 2023

Polyunsaturated fatty acids (PUFAs) undergo lipid peroxidation and conversion into malondialdehyde (MDA). MDA reacts with acetaldehyde to form malondialdehyde-modified low-density lipoprotein (MDA-LDL). We studied unsettled issues in the association...

  • Review
  • Open Access
92 Citations
8,505 Views
20 Pages

The Advanced Lipoxidation End-Product Malondialdehyde-Lysine in Aging and Longevity

  • Mariona Jové,
  • Natàlia Mota-Martorell,
  • Irene Pradas,
  • Meritxell Martín-Gari,
  • Victoria Ayala and
  • Reinald Pamplona

15 November 2020

The nonenzymatic adduction of malondialdehyde (MDA) to the protein amino groups leads to the formation of malondialdehyde-lysine (MDALys). The degree of unsaturation of biological membranes and the intracellular oxidative conditions are the main fact...

  • Article
  • Open Access
8 Citations
11,126 Views
7 Pages

31 August 2005

The present study examined the influence of synthetic N-(1,3-benzothiazol-2-yl)-N-(4,5-dihydro-1H-imidazol-2-yl) amine (2-Amdz) on levels of vitamins A, E and C and malondialdehyde (MDA) in rats. A total of 30 rats, divided into two groups, were used...

  • Article
  • Open Access
17 Citations
3,113 Views
11 Pages

6 October 2022

This paper focuses on the effect of malondialdehyde-induced oxidative modification (MiOM) on the gel properties of duck myofibrillar proteins (DMPs). DMPs were first prepared and treated with oxidative modification at different concentrations of malo...

  • Review
  • Open Access
61 Citations
13,762 Views
22 Pages

Alcohol, Aldehydes, Adducts and Airways

  • Muna Sapkota and
  • Todd A. Wyatt

5 November 2015

Drinking alcohol and smoking cigarettes results in the formation of reactive aldehydes in the lung, which are capable of forming adducts with several proteins and DNA. Acetaldehyde and malondialdehyde are the major aldehydes generated in high levels...

  • Article
  • Open Access
12 Citations
13,928 Views
10 Pages

Effect of Sodium Fluoride Ingestion on Malondialdehyde Concentration and the Activity of Antioxidant Enzymes in Rat Erythrocytes

  • José A. Morales-González,
  • José Gutiérrez-Salinas,
  • Liliana García-Ortiz,
  • María Del Carmen Chima-Galán,
  • Eduardo Madrigal-Santillán,
  • Jaime Esquivel-Soto,
  • César Esquivel-Chirino and
  • Manuel García-Luna y González-Rubio

11 June 2010

Fluoride intoxication has been shown to produce diverse deleterious metabolic alterations within the cell. To determine the effects of sodium fluoride (NaF) treatment on malondialdehyde (MDA) levels and on the activity of antioxidant enzymes in rat e...

  • Article
  • Open Access
1,133 Views
13 Pages

Time-Dependent Changes in Malondialdehyde and Free-Hemoglobin in Leukoreduced and Non-Leukoreduced Canine Packed Red Blood Cells Units During Storage

  • Arianna Miglio,
  • Aurora Barbetta,
  • Valentina Cremonini,
  • Olimpia Barbato,
  • Giovanni Ricci,
  • Valeria Toppi,
  • Luca Avellini,
  • Valentina Cavani and
  • Maria Teresa Antognoni

30 August 2025

Storage of Blood units determines the accumulation of harmful substances, such as malondialdehyde (MDA) and free hemoglobin (fHb). These may lead to several complications, including cardiovascular, neurodegenerative, and metabolic disorders in recipi...

  • Article
  • Open Access
11 Citations
4,378 Views
12 Pages

Plasma Malondialdehyde and Risk of New-Onset Diabetes after Transplantation in Renal Transplant Recipients: A Prospective Cohort Study

  • Manuela Yepes-Calderón,
  • Camilo G. Sotomayor,
  • António W. Gomes-Neto,
  • Rijk O.B. Gans,
  • Stefan P. Berger,
  • Gerald Rimbach,
  • Tuba Esatbeyoglu,
  • Ramón Rodrigo,
  • Johanna M. Geleijnse and
  • Stephan J.L. Bakker

New-onset diabetes after transplantation (NODAT) is a frequent complication in renal transplant recipients (RTR). Although oxidative stress has been associated with diabetes mellitus, data regarding NODAT are limited. We aimed to prospectively invest...

  • Article
  • Open Access
9 Citations
3,900 Views
15 Pages

Association of Serum Malondialdehyde Levels with Lipid Profile and Liver Function in Patients with Inflammatory Bowel Disease

  • Nayra Merino de Paz,
  • Marta Carrillo-Palau,
  • Alejandro Hernández-Camba,
  • Pedro Abreu-González,
  • Antonia de Vera-González,
  • Alejandra González-Delgado,
  • Candelaria Martín-González,
  • Miguel Á. González-Gay and
  • Iván Ferraz-Amaro

26 September 2024

Malondialdehyde (MDA) is a naturally occurring organic compound produced as a byproduct of lipid peroxidation. It serves as one of the most widely recognized biomarkers for oxidative stress. Elevated levels of MDA have been observed in patients with...

  • Article
  • Open Access
33 Citations
5,616 Views
10 Pages

Association between Pre-Transplant Serum Malondialdehyde Levels and Survival One Year after Liver Transplantation for Hepatocellular Carcinoma

  • Leonardo Lorente,
  • Sergio T. Rodriguez,
  • Pablo Sanz,
  • Pedro Abreu-González,
  • Dácil Díaz,
  • Antonia M. Moreno,
  • Elisa Borja,
  • María M. Martín,
  • Alejandro Jiménez and
  • Manuel A. Barrera

Previous studies have found higher levels of serum malondialdehyde (MDA) in hepatocellular carcinoma (HCC) patients compared to healthy controls and higher MDA concentrations in tumoral tissue of HCC patients than in non-tumoral tissue. However, the...

  • Article
  • Open Access
24 Citations
2,997 Views
15 Pages

22 July 2022

Lipid oxidation and protein oxidation occur side by side in meat. Here, the effect of malondialdehyde (MDA), the major product of lipid oxidation, on the digestibility of beef myofibrillar proteins (MP) was studied. MP samples were incubated with 0,...

  • Article
  • Open Access
6 Citations
2,594 Views
21 Pages

Monocytic Cell Adhesion to Oxidised Ligands: Relevance to Cardiovascular Disease

  • Robin N. Poston,
  • Jenna Chughtai,
  • Desara Ujkaj,
  • Huguette Louis,
  • David S. Leake and
  • Dianne Cooper

30 November 2022

Atherosclerosis, the major cause of vascular disease, is an inflammatory process driven by entry of blood monocytes into the arterial wall. LDL normally enters the wall, and stimulates monocyte adhesion by forming oxidation products such as oxidised...

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