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27 Results Found

  • Review
  • Open Access
14 Citations
6,149 Views
16 Pages

5 March 2021

In recent years, efforts have been devoted to improving the welfare of laboratory animals. Scientific progress and growing concerns over animal harm have pushed institutions to strengthen their laws to make science more humane and responsible. Europe...

(This article belongs to the Special Issue Animal Experimentation: State of the Art and Future Scenarios)
  • Commentary
  • Open Access
9 Citations
3,347 Views
15 Pages

19 March 2022

Globally, it is estimated that around 10% of the fish that are caught are discarded. This is considered to be a wasteful human marine activity since these fish are often dead or dying. To reduce the high discard rates of commercial fisheries, the Eur...

(This article belongs to the Special Issue Fish Welfare in Research and Fish Farming)
  • Article
  • Open Access
46 Citations
9,510 Views
11 Pages

The aim of this paper is to describe the essential points of Italian and European legislation governing the use of animals in biomedical experimentation. A close look will be taken at the principles of the 3Rs, which represent the mainstay of the leg...

  • Conference Report
  • Open Access
1,656 Views
18 Pages

XXVIII Annual Meeting of the Italian Association for Laboratory Animal Sciences

  • Viola Galligioni,
  • Marino Campagnol,
  • Sara Fuochi,
  • Valeria Pagano,
  • Marcello Raspa,
  • Silvia Sabbioni and
  • Paola Zarattini

The Italian Association for Laboratory Animal Sciences (AISAL) held its annual meeting in September 2022. The main topic of the meeting was the section ‘Quality Control of the Components in the Study’ of the PREPARE guidelines. Among the...

(This article belongs to the Proceedings of XXVIII Annual Meeting of the Italian Association for Laboratory Animal Sciences)
  • Feature Paper
  • Article
  • Open Access
63 Citations
16,996 Views
17 Pages

29 December 2018

Basic and applied laboratory research, whenever intrusive or invasive, presents substantial ethical challenges for ethical committees, be it with human beings or with non-human animals. In this paper we discuss the use of non-human primates (NHPs), m...

  • Article
  • Open Access
16 Citations
9,236 Views
16 Pages

10 September 2021

Techniques of stereotaxic surgery are commonly used in research laboratories by a range of students, technicians, and researchers. To meet the evolving requirements imposed by international legislation, and to promote the implementation of 3R rules (...

(This article belongs to the Special Issue The Welfare of Laboratory Animals)
  • Article
  • Open Access
20 Citations
9,484 Views
13 Pages

Regulating Companion Dog Welfare: A Comparative Study of Legal Frameworks in Western Countries

  • Søren Stig Andersen,
  • Iben Meyer,
  • Björn Forkman,
  • Søren Saxmose Nielsen and
  • Peter Sandøe

2 June 2021

There appear to be growing concerns among experts, NGOs, and members of the public about the welfare of companion dogs. With farm and laboratory animals, legislative initiatives have long been considered valuable tools in the management of welfare wh...

(This article belongs to the Special Issue Legal Aspects of the Human-Animal Relationship)
  • Article
  • Open Access
5 Citations
4,348 Views
17 Pages

Biological Containment for African Swine Fever (ASF) Laboratories and Animal Facilities: The Italian Challenge in Bridging the Present Regulatory Gap and Enhancing Biosafety and Biosecurity Measures

  • Silvia Pavone,
  • Carmen Iscaro,
  • Monica Giammarioli,
  • Maria Serena Beato,
  • Cecilia Righi,
  • Stefano Petrini,
  • Silva Costarelli and
  • Francesco Feliziani

30 January 2024

The African Swine Fever Virus (ASFV) is a DNA virus of the Asfarviridae family, Asfivirus genus. It is responsible for massive losses in pig populations and drastic direct and indirect economic impacts. The ever-growing handling of ASFV pathological...

(This article belongs to the Special Issue Biosecuring Animal Populations)
  • Communication
  • Open Access
6 Citations
5,392 Views
14 Pages

Animal Research beyond the Laboratory: Report from a Workshop on Places Other than Licensed Establishments (POLEs) in the UK

  • Alexandra Palmer,
  • Beth Greenhough,
  • Pru Hobson-West,
  • Reuben Message,
  • James N. Aegerter,
  • Zoe Belshaw,
  • Ngaire Dennison,
  • Roger Dickey,
  • Julie Lane and
  • Sarah Wolfensohn
  • + 7 authors

13 October 2020

Research involving animals that occurs outside the laboratory raises an array of unique challenges. With regard to UK legislation, however, it receives only limited attention in terms of official guidelines, support, and statistics, which are unsurpr...

(This article belongs to the Special Issue Animal Experimentation: State of the Art and Future Scenarios)
  • Commentary
  • Open Access
11 Citations
6,834 Views
22 Pages

21 October 2020

Previous histories of animal experimentation, e.g., Franco (2013) have focused on ethics, the law and the personalities involved, but not on the involvement of anaesthetics or analgesics. Given that these were major subjects of (UK) Parliamentary deb...

(This article belongs to the Special Issue Refinements to Animal Models for Biomedical Research)
  • Review
  • Open Access
30 Citations
16,060 Views
13 Pages

23 June 2021

Rumen content is a complex mixture of feed, water, fermentation products, and living organisms such as bacteria, fungi, and protozoa, which vary over time and with different feeds. As it is impossible to reproduce this complex system in the laborator...

(This article belongs to the Section Animal Welfare)
  • Review
  • Open Access
451 Citations
26,642 Views
22 Pages

17 September 2014

Food wastes are produced by a variety of sources, ranging from agricultural operations to household consumption. About 38% occurs during food processing. At present, the European Union legislation encourages the exploitation of co-products. This valo...

(This article belongs to the Section Natural Products Chemistry)
  • Article
  • Open Access
16 Citations
6,318 Views
14 Pages

Characterization of Suspected Crimes against Companion Animals in Portugal

  • Diana Araújo,
  • Carla Lima,
  • João R. Mesquita,
  • Irina Amorim and
  • Cristina Ochôa

20 September 2021

Animal crimes are a widespread phenomenon with serious implications for animal welfare, individual well-being and for society in general. These crimes are universal and represent a major problem in human/animal interaction. In Portugal, current law 6...

(This article belongs to the Section Veterinary Clinical Studies)
  • Article
  • Open Access
18 Citations
9,806 Views
24 Pages

Group and Single Housing of Male Mice: Collected Experiences from Research Facilities in Sweden

  • Josefina Zidar,
  • Elin M. Weber,
  • Birgit Ewaldsson,
  • Solveig Tjäder,
  • Josefin Lilja,
  • James Mount,
  • Camilla I. Svensson,
  • Emma Svensk,
  • Eva Udén and
  • Elin Törnqvist

21 November 2019

Animals used for scientific purposes are protected by EU legislation. Social animals should be kept in stable groups that enable species-typical social behavior and provide individuals with social comfort. However, when group-housing male mice, aggre...

(This article belongs to the Special Issue 60 Years of the Three Rs and Their Impact on Animal Welfare)
  • Review
  • Open Access
22 Citations
10,582 Views
19 Pages

21 January 2014

Laboratory classes in which animals are seriously harmed or killed, or which use cadavers or body parts from ethically debatable sources, are controversial within veterinary and other biomedical curricula. Along with the development of more humane te...

  • Abstract
  • Open Access
1,453 Views
2 Pages

Revisiting Nanotoxicology Tests—Miniaturized Approaches of Nanotoxicity Tests in Daphnids

  • Anne Leung,
  • Emma Rowan,
  • Dimitrios Kakavas,
  • Konstantinos Panagiotidis,
  • Keith D. Rochfort and
  • Konstantinos Grintzalis

The great increase in nanotechnology in the last 20 years has led to the alarming presence of nanomaterials in the environment as a new category of pollutants. Given the fact that legislation on nanomaterials is not concrete, the monitoring of their...

(This article belongs to the Proceedings of International Conference EcoBalt 2023 "Chemicals & Environment")
  • Article
  • Open Access
8 Citations
5,026 Views
17 Pages

The Impact of Soil Erosion on Biodiversity Conservation in Isiala Ngwa North LGA, Southeastern Nigeria

  • Godson Chinonyerem Asuoha,
  • Uchenna Paulinus Okafor,
  • Philip Ogbonnia Phil-Eze and
  • Romanus Udegbunam Ayadiuno

16 December 2019

The impact of soil erosion on the conservation of biodiversity in Isiala Ngwa North LGA, Southeastern Nigeria was examined. Data were obtained through focus group discussions and plant species enumeration. Diversity indices of plant species were deri...

(This article belongs to the Special Issue Environmental Impacts under Sustainable Conservation Management)
  • Review
  • Open Access
18 Citations
10,587 Views
14 Pages

20 March 2014

Irritant and allergic contact dermatitis are undesired side effects in the development of drugs and cosmetics as well as after contact with environmental or industrial chemicals. Over the last decades, a great deal of progress has been made in the de...

  • Article
  • Open Access
10 Citations
3,514 Views
19 Pages

Scale-Up to Pilot of a Non-Axenic Culture of Thraustochytrids Using Digestate from Methanization as Nitrogen Source

  • Denis de la Broise,
  • Mariana Ventura,
  • Luc Chauchat,
  • Maurean Guerreiro,
  • Teo Michez,
  • Thibaud Vinet,
  • Nicolas Gautron,
  • Fabienne Le Grand,
  • Antoine Bideau and
  • Philippe Soudant
  • + 3 authors

2 August 2022

The production of non-fish based docosahexaenoic acid (DHA) for feed and food has become a critical need in our global context of over-fishing. The industrial-scale production of DHA–rich Thraustochytrids could be an alternative, if costs turne...

(This article belongs to the Special Issue Marine Thraustochytrids: Biology, Chemical Ecology and Biotechnology)
  • Review
  • Open Access
7 Citations
3,014 Views
33 Pages

Biomaterials and biomedical devices interact with the human body at different levels. At one end of the spectrum, medical devices in contact with tissue pose risks depending on whether they are deployed on the skin or implanted. On the other hand, fo...

  • Systematic Review
  • Open Access
15 Citations
3,786 Views
13 Pages

Refinement in the European Union: A Systematic Review

  • Alina Díez-Solinska,
  • Oscar Vegas and
  • Garikoitz Azkona

23 November 2022

Refining experiments and housing conditions so as to cause the minimum possible pain and distress is one of the three principles (3Rs) on which Directive 2010/63/EU is based. In this systematic review, we aimed to identify and summarize published adv...

(This article belongs to the Special Issue Implementing the 3Rs in Laboratory Animal Research—From Theory to Practice)
  • Communication
  • Open Access
8 Citations
4,275 Views
9 Pages

Food Safety Monitoring of Salmonella spp. in Northern Italy 2019–2021

  • Daniela Manila Bianchi,
  • Paola Barzanti,
  • Daniela Adriano,
  • Francesca Martucci,
  • Monica Pitti,
  • Carla Ferraris,
  • Irene Floris,
  • Roberta La Brasca,
  • Carmela Ligotti and
  • Lucia Decastelli
  • + 5 authors

Salmonella is the second most frequent bacterial pathogen involved in human gastrointestinal outbreaks in the European Union; it can enter the food-production chain from animal or environmental sources or from asymptomatic food operators. European fo...

(This article belongs to the Special Issue Women’s Special Issue Series: Pathogens)
  • Article
  • Open Access
77 Citations
15,525 Views
27 Pages

Spread of the Emerging Viral Hemorrhagic Septicemia Virus Strain, Genotype IVb, in Michigan, USA

  • Mohamed Faisal,
  • Megan Shavalier,
  • Robert K. Kim,
  • Elena V. Millard,
  • Michelle R. Gunn,
  • Andrew D. Winters,
  • Carolyn A. Schulz,
  • Alaa Eissa,
  • Michael V. Thomas and
  • James Winton
  • + 2 authors

3 May 2012

In 2003, viral hemorrhagic septicemia virus (VHSV) emerged in the Laurentian Great Lakes causing serious losses in a number of ecologically and recreationally important fish species. Within six years, despite concerted managerial preventive measures,...

(This article belongs to the Special Issue Viruses Infecting Fish, Amphibians, and Reptiles)
  • Review
  • Open Access
196 Citations
21,789 Views
25 Pages

2 August 2020

Wood is a renewable, versatile material with multiple applications and the largest terrestrial pool of sequestered carbon. However, it is susceptible to degradation, mainly caused by wood-decaying fungi. Since several traditional wood preservatives h...

(This article belongs to the Special Issue Natural Products and Their Semi-synthetic Derivatives against Bacteria, Fungi and Parasites)
  • Article
  • Open Access
16 Citations
6,102 Views
12 Pages

Monitoring of Aflatoxin M1 in Various Origins Greek Milk Samples Using Liquid Chromatography Tandem Mass Spectrometry

  • Anthi Panara,
  • Maria Katsa,
  • Marios Kostakis,
  • Erasmia Bizani and
  • Nikolaos S. Thomaidis

Aflatoxin M1(AFM1), a major metabolite of Aflatoxin B1(AFB1), has been identified as a potential contaminant in dairy products. Because of its possible carcinogenicity, the legislation limits as set by Commission Regulation (EC) No. 1881/2006 are ver...

(This article belongs to the Section Analysis of Food and Beverages)
  • Article
  • Open Access
10 Citations
3,187 Views
10 Pages

12 March 2021

Mammalian animal toxicity of ochratoxin A (OTA) has focused largely in the past half-century on pigs because of initial recognition of it as a principal cause of intermittent growth suppression and renal disease caused by mouldy feed. Subsequent clas...

(This article belongs to the Special Issue The Effects of Mycotoxins on Human and Animal Health—a Special Focus on the Cellular and Molecular Mechanisms Responsible for Mycotoxin Toxicity)
  • Article
  • Open Access
28 Citations
4,421 Views
22 Pages

Active Surveillance for Highly Pathogenic Avian Influenza Viruses in Wintering Waterbirds in Northeast Italy, 2020–2021

  • Federica Gobbo,
  • Diletta Fornasiero,
  • Maria Alessandra De Marco,
  • Bianca Zecchin,
  • Paolo Mulatti,
  • Mauro Delogu and
  • Calogero Terregino

The increasing involvement of wild waterfowl in H5 Highly Pathogenic Avian Influenza Virus (HPAIV) circulation continues to pose a threat to animal and public health worldwide. In winter 2020–2021, two field surveillance activities were carried out o...

(This article belongs to the Special Issue Ecology of Influenza A Viruses)