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37 Results Found

  • Article
  • Open Access
819 Views
16 Pages

IGSMNet: Ingredient-Guided Semantic Modeling Network for Food Nutrition Estimation

  • Donglin Zhang,
  • Weixiang Shi,
  • Boyuan Ma,
  • Weiqing Min and
  • Xiao-Jun Wu

30 October 2025

In recent years, food nutrition estimation has received growing attention due to its critical role in dietary analysis and public health. Traditional nutrition assessment methods often rely on manual measurements and expert knowledge, which are time-...

  • Article
  • Open Access
32 Citations
7,773 Views
12 Pages

Bioassay-Guided Isolation of DPP-4 Inhibitory Fractions from Extracts of Submerged Cultured of Inonotus obliquus

  • Yan Geng,
  • Zhen-Ming Lu,
  • Wei Huang,
  • Hong-Yu Xu,
  • Jin-Song Shi and
  • Zheng-Hong Xu

16 January 2013

Inonotus obliquus is a medicinal mushroom used in Russian and Eastern European folk medicine for the treatment of gastrointestinal cancer, cardiovascular disease and diabetes. Previous studies in our laboratory have demonstrated that the mycelium pow...

  • Article
  • Open Access
4 Citations
3,520 Views
16 Pages

26 November 2024

Food semantic segmentation is of great significance in the field of computer vision and artificial intelligence, especially in the application of food image analysis. Due to the complexity and variety of food, it is difficult to effectively handle th...

  • Article
  • Open Access
2 Citations
2,824 Views
16 Pages

Seaweed-Based Bioplastics: Data Mining Ingredient–Property Relations from the Scientific Literature

  • Fernanda Véliz,
  • Thulasi Bikku,
  • Davor Ibarra-Pérez,
  • Valentina Hernández-Muñoz,
  • Alysia Garmulewicz and
  • Felipe Herrera

1 February 2025

Automated analysis of the scientific literature using natural language processing (NLP) can accelerate the identification of potentially unexplored formulations that enable innovations in materials engineering with fewer experimentation and testing c...

  • Review
  • Open Access
51 Citations
10,576 Views
26 Pages

Term Infant Formulas Influencing Gut Microbiota: An Overview

  • Valentina Fabiano,
  • Flavia Indrio,
  • Elvira Verduci,
  • Valeria Calcaterra,
  • Tudor Lucian Pop,
  • Alessandra Mari,
  • Gian Vincenzo Zuccotti,
  • Fugen Cullu Cokugras,
  • Massimo Pettoello-Mantovani and
  • Olivier Goulet

23 November 2021

Intestinal colonization of the neonate is highly dependent on the term of pregnancy, the mode of delivery, the type of feeding [breast feeding or formula feeding]. Postnatal immune maturation is dependent on the intestinal microbiome implementation a...

  • Article
  • Open Access
2 Citations
2,818 Views
13 Pages

28 April 2023

Systematic treatment descriptions to standardize and evaluate management of fatigue after acquired brain injury (ABI) are lacking. The purpose of this multi-phase qualitative study was to formulate a treatment model for promoting self-management of f...

  • Article
  • Open Access
1,220 Views
18 Pages

Targeting Melanin Production: The Safety of Tyrosinase Inhibition

  • Steffen Erler,
  • Ludger Kolbe,
  • Abdulkarim Najjar,
  • Andreas Schepky,
  • Ahmed Kamal,
  • Daniela Lange and
  • Tamara Rogers

Hyperpigmentation remains a persistent dermatological challenge with limited treatment options. Among available strategies, tyrosinase inhibition stands out as the current most effective and safest approach for suppressing melanin synthesis. Thiamido...

  • Article
  • Open Access
20 Citations
6,219 Views
21 Pages

Insights into Drivers of Liking for Avocado Pulp (Persea americana): Integration of Descriptive Variables and Predictive Modeling

  • Luis Martín Marín-Obispo,
  • Raúl Villarreal-Lara,
  • Dariana Graciela Rodríguez-Sánchez,
  • Armando Del Follo-Martínez,
  • María de la Cruz Espíndola Barquera,
  • Jesús Salvador Jaramillo-De la Garza,
  • Rocío I. Díaz de la Garza and
  • Carmen Hernández-Brenes

6 January 2021

Trends in new food products focus on low-carbohydrate ingredients rich in healthy fats, proteins, and micronutrients; thus, avocado has gained worldwide attention. This study aimed to use predictive modeling to identify the potential sensory drivers...

  • Article
  • Open Access
2 Citations
1,109 Views
22 Pages

Navigating the Deep Eutectic Solvent Landscape: Experimental and Machine Learning Solubility Explorations of Syringic, p-Coumaric, and Caffeic Acids

  • Piotr Cysewski,
  • Tomasz Jeliński,
  • Maciej Przybyłek,
  • Natalia Gliniewicz,
  • Marcel Majkowski and
  • Michał Wąs

16 October 2025

Efficiently identifying suitable solvents for active pharmaceutical ingredients (APIs) is critical in drug formulation, yet the vast number of possible solvent-solute combinations presents a significant experimental challenge. This study addresses th...

  • Review
  • Open Access
96 Citations
21,033 Views
20 Pages

Infant Formula Supplemented with Biotics: Current Knowledge and Future Perspectives

  • Seppo Salminen,
  • Bernd Stahl,
  • Gabriel Vinderola and
  • Hania Szajewska

30 June 2020

Breastfeeding is natural and the optimal basis of infant nutrition and development, with many benefits for maternal health. Human milk is a dynamic fluid fulfilling an infant’s specific nutritional requirements and guiding the growth, developme...

  • Article
  • Open Access
8 Citations
3,551 Views
27 Pages

1 April 2020

This study follows from Maurel et al., Phys. Rev. B 98, 134311 (2018), where we reported on direct numerical observations of out-of-plane shear surface waves propagating along an array of plates atop a guiding layer, as a model for a forest of trees....

  • Article
  • Open Access
4,873 Views
23 Pages

Unlocking Nature’s Anti-Aging Secrets: The Potential of Natural Mineral Waters Combined with Plant Extracts in Cosmetics

  • Ana Rita Gama,
  • Carolina P. Gomes,
  • Cátia Caetano,
  • Ana Sofia Oliveira,
  • Joana Rolo,
  • Lillian Barros,
  • Paula Plasencia,
  • Juliana Garcia,
  • Daniela Correia and
  • Rita Palmeira-de-Oliveira
  • + 3 authors

Skin aging is influenced by intrinsic and extrinsic factors, leading to structural changes in the skin. Current anti-aging cosmetic trends emphasize innovative natural ingredients, including plant extracts, thermal waters, and botanical hydrolats. Th...

  • Article
  • Open Access
5 Citations
2,106 Views
15 Pages

22 August 2024

This study aimed to evaluate the digestive efficiency of food matrices supplemented with milk fat globule membrane isolated from buttermilk (BM-MFGM), using the INFOGEST in vitro digestion protocol hyphenated with the assessment of the digested mater...

  • Article
  • Open Access
21 Citations
5,609 Views
25 Pages

In Silico Drug Screening Based Development of Novel Formulations for Onychomycosis Management

  • Mahak Fatima,
  • Sadia Monawwar,
  • Sradhanjali Mohapatra,
  • Thomson Santosh Alex,
  • Abdulrahman Ahmed,
  • Mohamad Taleuzzaman,
  • Asgar Ali,
  • Mohammad Javed Ansari,
  • Mohd. Aamir Mirza and
  • Zeenat Iqbal

18 November 2021

Onychomycosis is a prominent fungal infection that causes discoloration, thickening, and mutilation leading to the separation of the nail from the nail bed. Treatment modalities for onychomycosis may include oral, topical, or combination therapy with...

  • Article
  • Open Access
30 Citations
4,132 Views
28 Pages

An Updated Risk Assessment as Part of the QbD-Based Liposome Design and Development

  • Zsófia Németh,
  • Edina Pallagi,
  • Dorina Gabriella Dobó,
  • Gábor Kozma,
  • Zoltán Kónya and
  • Ildikó Csóka

Liposomal formulation development is a challenging process. Certain factors have a critical influence on the characteristics of the liposomes, and even the relevant properties can vary based on the predefined interests of the research. In this paper,...

  • Article
  • Open Access
13 Citations
3,704 Views
18 Pages

Magnaporthe oryzae (M. oryzae) is a typical cause of rice blast in agricultural production. Isobavachalcone (IBC), an active ingredient of Psoralea corylifolia L. extract, is an effective fungicide against rice blast. To determine the mechanism of IB...

  • Feature Paper
  • Article
  • Open Access
4 Citations
3,933 Views
23 Pages

Superfluid Neutron Matter with a Twist

  • Georgios Palkanoglou and
  • Alexandros Gezerlis

26 January 2021

Superfluid neutron matter is a key ingredient in the composition of neutron stars. The physics of the inner crust are largely dependent on those of its S-wave neutron superfluid, which has made its presence known through pulsar glitches and modificat...

  • Article
  • Open Access
2,297 Views
25 Pages

Unraveling Biotic and Abiotic Factors Shaping Sugarcane Straw Polyphenolic Richness: A Gateway to Artificial Intelligence-Driven Crop Management

  • Ana L. S. Oliveira,
  • Maria João Carvalho,
  • Poliana Silva,
  • Manuela Pintado and
  • Ana Raquel Madureira

27 December 2023

Sugarcane straw (Saccharum officinarum) is a valuable coproduct renowned for its abundant polyphenolic content. However, extracting these polyphenols for natural ingredients faces challenges due to their inherent variability, influenced by biotic str...

  • Article
  • Open Access
20 Citations
4,234 Views
22 Pages

9 October 2021

Solubility enhancement of poorly soluble active pharmaceutical ingredients is of crucial importance for drug development and processing. Extensive experimental screening is limited due to the vast number of potential solvent combinations. Hence, theo...

  • Review
  • Open Access
45 Citations
8,403 Views
24 Pages

This review systematically examines the pivotal applications of the Density Functional Theory (DFT) in drug formulation design, emphasizing its capability to elucidate molecular interaction mechanisms through quantum mechanical calculations. By solvi...

  • Review
  • Open Access
1 Citations
1,445 Views
23 Pages

14 October 2025

Background: Gut microbiome dysbiosis is implicated in numerous chronic diseases. While quinoa possesses a rich nutritional profile with prebiotic potential, the specific capacity of its bioactive peptides to modulate gut microbial communities is not...

  • Article
  • Open Access
33 Citations
7,220 Views
12 Pages

Sustainability of Palm Oil: Drivers of Consumers’ Preferences

  • Massimiliano Borrello,
  • Azzurra Annunziata and
  • Riccardo Vecchio

4 September 2019

In recent years, the public debate on the health and sustainability of palm oil and its use by food industries has strongly influenced consumer choices. Consequently, palm oil-free products have asserted their image as healthier and more sustainable...

  • Article
  • Open Access
1 Citations
1,884 Views
13 Pages

Design and Optimization of 3D-Printed Tablets Containing Mucuna Extracts for Erectile Dysfunction Management: A DoE-Guided Study

  • Ratchapoom Wattanawiggan,
  • Sunee Chansakaow,
  • Pensak Jantrawut,
  • Pattaraporn Panraksa,
  • Jutamas Jiaranaikulwanitch,
  • Suruk Udomsom,
  • Patnarin Worajittiphon and
  • Pratchaya Tipduangta

18 August 2024

Erectile dysfunction (ED) refers to the inability of the penis to maintain a firm erection during sexual activity. Mucuna, or M. pruriens, contains levodopa, a compound showing promise in ED treatment. However, formulating Mucuna extract into tablet...

  • Article
  • Open Access
1 Citations
2,031 Views
15 Pages

Transforming Agri-Waste into Health Innovation: A Circular Framework for Sustainable Food Design

  • Smita Mortero,
  • Jirarat Anuntagool,
  • Achara Chandrachai and
  • Sanong Ekgasit

23 July 2025

This study addresses the problem of agricultural waste utilization and nutrition for older adults by developing a food product based on a circular design approach. Pineapple core was used to produce a clean-label dietary powder without chemical or en...

  • Article
  • Open Access
280 Views
28 Pages

29 December 2025

Urban welfare can deteriorate over a few weeks, yet most official indicators are only updated quarterly. This mismatch in time scales leaves city administrations effectively blind to the early stages of emerging crises, especially in areas where vuln...

  • Article
  • Open Access
12 Citations
3,827 Views
16 Pages

RSM Optimization for the Recovery of Technofunctional Protein Extracts from Porcine Hearts

  • Dolors Parés,
  • Mònica Toldrà,
  • Estel Camps,
  • Juan Geli,
  • Elena Saguer and
  • Carmen Carretero

25 November 2020

Meat byproducts, such as the internal organs from slaughtered animals, are usually underutilized materials with low commercial value. The functional (emulsifying, gelling, and foaming) properties of soluble protein extracts derived from pork hearts w...

  • Article
  • Open Access
34 Citations
13,766 Views
17 Pages

Agar Biopolymer Films for Biodegradable Packaging: A Reference Dataset for Exploring the Limits of Mechanical Performance

  • Valentina Hernández,
  • Davor Ibarra,
  • Johan F. Triana,
  • Bastian Martínez-Soto,
  • Matías Faúndez,
  • Diego A. Vasco,
  • Leonardo Gordillo,
  • Felipe Herrera,
  • Claudio García-Herrera and
  • Alysia Garmulewicz

1 June 2022

This article focuses on agar biopolymer films that offer promise for developing biodegradable packaging, an important solution for reducing plastics pollution. At present there is a lack of data on the mechanical performance of agar biopolymer films...

  • Article
  • Open Access
4 Citations
2,671 Views
13 Pages

18 February 2024

This study aimed to develop a fermented puree mixture containing plant-based ingredients and potential probiotic strains Lacticaseibacillus rhamnosusK3 and Lactobacillus johnsonii K4. The survival of potential probiotic strains, changes in sugar and...

  • Article
  • Open Access
16 Citations
4,956 Views
16 Pages

27 January 2023

Healthy eating is vital in preventing obesity and long-term non-communicable diseases. This study explores potential family facilitators of, barriers to and strategies for healthy eating among adolescents in Chinese families to guide the development...

  • Article
  • Open Access
1,191 Views
20 Pages

Background/Objectives: Fixed-dose combinations (FDCs) hold significant clinical value for the management of hypertension, diabetes and other chronic diseases. However, since the complexity of formulations, generic compounds require both in vitro phar...

  • Article
  • Open Access
6 Citations
3,035 Views
14 Pages

Preparation of Slow-Release Insecticides from Biogas Slurry: Effectiveness of Ion Exchange Resin in the Adsorption and Release of Ammonia Nitrogen

  • Quanguo Zhang,
  • Zexian Liu,
  • Francesco Petracchini,
  • Chaoyang Lu,
  • Yameng Li,
  • Zhiping Zhang,
  • Valerio Paolini and
  • Huan Zhang

21 August 2021

The insecticidal ingredient in a biogas solution being fully utilized by cation exchange resin to produce slow-release insecticide is of great social value. In this work, the feasibility of ammonia nitrogen in a biogas slurry loaded on resin as a slo...

  • Article
  • Open Access
1 Citations
2,083 Views
14 Pages

Metastable Racemic Ibuprofen Supercooled Liquid

  • Tuanjia Li,
  • Wangchuan Xiao,
  • Shizhao Ren,
  • Rongrong Xue and
  • Fenghua Chen

28 November 2024

Amorphous solid dispersions are good candidates for improving solubility in water and the oral bioavailability of poorly water-soluble active pharmaceutical ingredients (APIs). Amorphous solids become supercooled liquids when the temperature reaches...

  • Review
  • Open Access
29 Citations
3,817 Views
22 Pages

Neutrino Flavor Model Building and the Origins of Flavor and CP Violation

  • Yahya Almumin,
  • Mu-Chun Chen,
  • Murong Cheng,
  • Víctor Knapp-Pérez,
  • Yulun Li,
  • Adreja Mondol,
  • Saúl Ramos-Sánchez,
  • Michael Ratz and
  • Shreya Shukla

12 December 2023

The neutrino sector offers one of the most sensitive probes of new physics beyond the Standard Model of Particle Physics (SM). The mechanism of neutrino mass generation is still unknown. The observed suppression of neutrino masses hints at a large sc...

  • Article
  • Open Access
1,131 Views
18 Pages

23 November 2025

Reactive oxygen species (ROS) generated by ultraviolet (UV) radiation accelerate skin aging by activating matrix metalloproteinase-1 (MMP-1) and mitogen-activated protein kinase (MAPK) signaling pathways. Therefore, antioxidants that can suppress ROS...

  • Article
  • Open Access
3 Citations
2,542 Views
13 Pages

6 August 2022

The Kleier model and Carrier-mediated theory are effective for molecularly designing pesticides with phloem mobility. However, the single Kleier model or Carrier-mediated theory cannot achieve a reliable explanation of the phloem mobility of all exog...

  • Article
  • Open Access
2 Citations
5,877 Views
25 Pages

From Sea to Science: Coral Aquaculture for Sustainable Anticancer Drug Development

  • Hung-Yu Lin,
  • Tsen-Ni Tsai,
  • Kai-Cheng Hsu,
  • Yu-Ming Hsu,
  • Lin-Chien Chiang,
  • Mohamed El-Shazly,
  • Ken-Ming Chang,
  • Yu-Hsuan Lin,
  • Shang-Yi Tu and
  • Mei-Chin Lu
  • + 3 authors

19 July 2024

Marine natural products offer immense potential for drug development, but the limited supply of marine organisms poses a significant challenge. Establishing aquaculture presents a sustainable solution for this challenge by facilitating the mass produ...

  • Article
  • Open Access
214 Views
19 Pages

2 January 2026

The widespread use of antibiotics, combined with pervasive exposure to diverse environmental media, has intensified the global challenge of antibiotic resistance. Accumulating evidence reveals that beyond direct antibiotic pressure, residual non-anti...