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23 Results Found

  • Article
  • Open Access
1 Citations
1,480 Views
23 Pages

9 February 2026

In most AFM nanoindentation experiments on soft biological samples, classical contact mechanics models, such as Hertz or Sneddon’s equations, are commonly employed to determine the Young’s modulus. However, biological materials are inhere...

(This article belongs to the Section Materials Engineering)
  • Article
  • Open Access
15 Citations
4,646 Views
16 Pages

AFM Indentation on Highly Heterogeneous Materials Using Different Indenter Geometries

  • Stylianos Vasileios Kontomaris,
  • Andreas Stylianou,
  • Georgios Chliveros and
  • Anna Malamou

18 April 2023

Hertzian mechanics is the most frequently used theory for data processing in Atomic Force Microscopy (AFM) indentation experiments on soft biological samples, due to its simplicity and significant scientific results previously published. For instance...

(This article belongs to the Special Issue Feature Papers in Material Mechanics)
  • Article
  • Open Access
1 Citations
1,848 Views
19 Pages

5 November 2025

Soft robots demonstrate great potential for underwater exploration, particularly in tasks such as locomotion and biological sampling in fragile marine habitats. However, developing new forms of interaction with underwater life remains a challenge due...

(This article belongs to the Special Issue Soft Sensors and Sensing Techniques)
  • Review
  • Open Access
1 Citations
2,630 Views
12 Pages

Adjunctive Use of Biologics in Alveolar Ridge Preservation: A Narrative Review

  • Celine Soon,
  • Pradeep Koppolu and
  • Leticia Algarves Miranda

15 August 2025

Background: The purpose of alveolar ridge preservation (ARP) is to minimise the physiological alveolar ridge reduction occurring after dental extraction, which can prevent the need for future alveolar ridge augmentation. Biologic materials (biologics...

  • Review
  • Open Access
1,822 Views
25 Pages

Hydroxyapatite-Based Biomaterials in Dentistry: Functional Performance and Clinical Relevance—A Narrative Review

  • Daniela Argatu,
  • Andrei Georgescu,
  • Ionut Luchian,
  • Florin Razvan Curca and ,
  • Monica Mihaela Scutariu,
  • Dana Gabriela Budala,
  • Nicoleta Tofan,
  • Vlad Constantin,
  • Cristian Cojocaru and
  • Florinel Cosmin Bida
  • + 5 authors+ 0 author

18 May 2026

Hydroxyapatite-based biomaterials are widely investigated for oral-tissue-healing applications; however, the available literature is heterogeneous in terms of material design, experimental models, and reported outcomes. This narrative review synthesi...

(This article belongs to the Collection Synthesis, Testing and Mechanical Behavior of Dental Biomaterials at Different Clinical Parameters)
  • Review
  • Open Access
26 Citations
6,863 Views
16 Pages

1 December 2020

Structured heterogeneous materials are ubiquitous in a biological system and are now adopted in structural engineering to achieve tailor-made properties in metallic materials. The present paper is an overview of the unique network type heterogeneous...

(This article belongs to the Special Issue News Trends in Powder Metallurgy: Microstructures, Properties, Durability)
  • Review
  • Open Access
108 Views
17 Pages

28 October 2026

Titanium and Ti-based alloys are widely used in dentistry, where their interfaces face chemical, microbial, mechanical, and tissue challenges. This focused narrative review considers endosseous and transmucosal implant interfaces, crowns, orthodontic...

(This article belongs to the Special Issue Surface Engineering and Protective Coatings for Light Metals: Processing, Properties, and Applications)
  • Review
  • Open Access
17 Citations
5,804 Views
28 Pages

Cross-Scale Biological Models of Species for Future Biomimetic Composite Design: A Review

  • Wenda Song,
  • Zhengzhi Mu,
  • Zhiyan Zhang,
  • Yufei Wang and ,
  • Handong Hu,
  • Zhe Ma,
  • Liewei Huang,
  • Ze Wang,
  • Binjie Zhang and
  • Luquan Ren
  • + 11 authors+ 6 authors

26 October 2021

The rise in structural performance requirements in engineering is driving the research and development of stronger, stiffer, and lighter materials. However, most traditional artificial materials are unable to meet the needs of modern industrial and t...

(This article belongs to the Special Issue Mechanical Bionic and Bio-Inspired Interface Materials)
  • Review
  • Open Access
21 Citations
5,271 Views
29 Pages

More than a Confinement: “Soft” and “Hard” Enzyme Entrapment Modulates Biological Catalyst Function

  • Grazia Cottone,
  • Sergio Giuffrida,
  • Stefano Bettati,
  • Stefano Bruno and ,
  • Barbara Campanini,
  • Marialaura Marchetti,
  • Stefania Abbruzzetti,
  • Cristiano Viappiani,
  • Antonio Cupane and
  • Luca Ronda
  • + 6 authors+ 1 author

4 December 2019

Catalysis makes chemical and biochemical reactions kinetically accessible. From a technological point of view, organic, inorganic, and biochemical catalysis is relevant for several applications, from industrial synthesis to biomedical, material, and...

(This article belongs to the Special Issue Immobilization of Enzymes)
  • Article
  • Open Access
5 Citations
3,770 Views
14 Pages

Nanoscale Material Heterogeneity of Glowworm Capture Threads Revealed by AFM

  • Dakota Piorkowski,
  • Bo-Ching He,
  • Sean J. Blamires,
  • I-Min Tso and
  • Deborah M. Kane

Adhesive materials used by many arthropods for biological functions incorporate sticky substances and a supporting material that operate synergistically by exploiting substrate attachment and energy dissipation. While there has been much focus on the...

(This article belongs to the Special Issue Frontiers in Silk Science-How Silks/Biomimetic Polymers Solve Specific Challenges?)
  • Article
  • Open Access
34 Citations
7,806 Views
14 Pages

30 May 2022

Flexible and soft bioelectronics used on skin tissue have attracted attention for the monitoring of human health. In addition to typical metal-based rigid electronics, soft polymeric materials, particularly conductive hydrogels, have been actively de...

(This article belongs to the Special Issue Advances in Cellulose-Based Hydrogels)
  • Review
  • Open Access
41 Citations
8,933 Views
31 Pages

Biological structures optimized through natural selection provide valuable insights for engineering load-bearing components. This paper reviews six key strategies evolved in nature for efficient mechanical load handling: hierarchically structured com...

(This article belongs to the Special Issue Learning from Nature—2nd Edition: Bionics in Design Practice)
  • Review
  • Open Access
3 Citations
1,805 Views
51 Pages

Brick by Brick the Wall Is Being Built: Particle-Based Scaffolds for Regenerative Medicine

  • Viktor Korzhikov-Vlakh,
  • Lei Wang,
  • Sofia Morozova,
  • Ekaterina Sinitsyna and ,
  • Tatiana Tennikova and
  • Evgenia Korzhikova-Vlakh
  • + 1 author+ 0 author

4 December 2025

Tissue engineering offers a promising solution by developing scaffolds that mimic the extracellular matrix and guide cellular growth and differentiation. Recent evidence suggests that scaffolds must provide not only biocompatibility and appropriate m...

(This article belongs to the Section Polymer Applications)
  • Systematic Review
  • Open Access
629 Views
15 Pages

31 August 2026

Background and Objectives: Platelet-rich fibrin (PRF) has been widely investigated as a biological material to enhance healing after tooth extraction; however, its clinical effectiveness remains uncertain. This systematic review evaluates the availab...

(This article belongs to the Special Issue Oral and Maxillofacial Surgery: Clinical Advances and Future Directions)
  • Article
  • Open Access
18 Citations
5,382 Views
13 Pages

Magnetoelastic Sensor Optimization for Improving Mass Monitoring

  • William S. Skinner,
  • Sunny Zhang,
  • Robert E. Guldberg and
  • Keat Ghee Ong

22 January 2022

Magnetoelastic sensors, typically made of magnetostrictive and magnetically-soft materials, can be fabricated from commercially available materials into a variety of shapes and sizes for their intended applications. Since these sensors are wirelessly...

(This article belongs to the Section Physical Sensors)
  • Review
  • Open Access
4 Citations
2,199 Views
12 Pages

Chest Wall Resection and Reconstruction Following Cancer

  • Francesco Petrella,
  • Andrea Cara,
  • Enrico Mario Cassina,
  • Lidia Libretti and ,
  • Emanuele Pirondini,
  • Federico Raveglia,
  • Maria Chiara Sibilia and
  • Antonio Tuoro
  • + 3 authors+ 0 author

16 December 2025

The chest wall represents a complex musculoskeletal structure that provides protection to intrathoracic organs, mechanical support for respiration, and mobility for the upper limbs. Neoplastic diseases of the chest wall encompass a heterogeneous grou...

(This article belongs to the Section Thoracic Oncology)
  • Review
  • Open Access
1,200 Views
49 Pages

Multinuclear NMR and MRI Beyond Proton Imaging: Principles, Contrast Mechanisms, and Applications in Materials and Biomedicine

  • Dorota Bartusik-Aebisher,
  • Klaudia Dynarowicz,
  • Barbara Smolak,
  • Rostyslav Marunych and ,
  • Wiesław Guz and
  • David Aebisher
  • + 1 author+ 0 author

Magnetic resonance techniques have evolved beyond conventional proton-based imaging, enabling access to a broader range of nuclei that provide complementary structural, functional, and molecular information. This review presents a comprehensive overv...

(This article belongs to the Special Issue Application of NMR Spectroscopy in Biomolecules: 2nd Edition)
  • Review
  • Open Access
31 Citations
5,298 Views
24 Pages

30 November 2021

Biomineralization is the process by which organisms produce hard inorganic matter from soft tissues with outstanding control of mineral deposition in time and space. For this purpose, organisms deploy a sophisticated “toolkit” that has re...

(This article belongs to the Collection Feature Papers in 'Macromolecules')
  • Review
  • Open Access
812 Views
33 Pages

Silk-Derived 3D-Bioprinted Scaffolds for Neural Repair and Nerve Regeneration: A Comprehensive Review

  • Alynah J. Adams,
  • Sanjana Challa,
  • Cynthia Yan,
  • Isabella Beltz and ,
  • Alexa Kambol,
  • Kaavian Shariati,
  • Jocelyn Hunt,
  • Charlotte Thomas,
  • Dorien I. Schonebaum and
  • Samuel J. Lin
  • + 7 authors+ 2 authors

26 May 2026

Traumatic injuries often result in nerve tissue damage and functional deficits due to limited regeneration. Silk fibroin, a biopolymer with inherent biocompatibility and tunable properties, is a promising material for 3D-bioprinted neural tissue scaf...

(This article belongs to the Section Medical Research)
  • Communication
  • Open Access
4 Citations
3,104 Views
13 Pages

“From Drowning to Treading Water”: Adolescents and Young Adults Living with Incurable and Indolent Metastatic Soft Tissue Sarcoma for More than Two Years

  • Paul R. D’Alessandro,
  • Caitlin E. Homanick,
  • Brittany D. Cooper,
  • Katelyn Ferguson and ,
  • Hillary Rutan and
  • Joseph G. Pressey
  • + 1 author+ 0 author

28 January 2025

Introduction: Adolescent/young adult (AYA) patients with metastatic soft tissue sarcoma (STS) typically face a dismal prognosis. However, a subset of patients with incurable disease lives beyond two years. Due to the rarity of diagnoses and inherent...

(This article belongs to the Special Issue Quality of Life and Side Effects Management in Cancer Treatment (Volume II))
  • Review
  • Open Access
4 Citations
2,193 Views
20 Pages

The Emerging Role of Hyaluronic Acid as a Multifunctional Regenerative Agent in Periodontal Healing

  • Andrei-Mario Bădărău-Șuster,
  • Amelia Tero-Vescan and
  • Mark Slevin

28 February 2026

Periodontitis is a multifactorial inflammatory disease characterized by dysbiotic microbial communities and progressive destruction of the supporting periodontal tissues, ultimately leading to alveolar bone loss. Achieving predictable periodontal reg...

(This article belongs to the Special Issue Recent Advances in Hydrogels for Tissue Engineering Applications)
  • Article
  • Open Access
578 Views
22 Pages

An Approximate Force–Indentation Equation for n-Sided Blunt Pyramidal Indenters

  • Stylianos Vasileios Kontomaris,
  • Ioannis Psychogios,
  • Anna Malamou and
  • Andreas Stylianou

1 September 2026

Accurate AFM nanoindentation analysis requires models that account for the rounded apex of real pyramidal indenters. Although exact force-indentation equations for n-sided blunt pyramids exist, their numerical complexity limits routine use. In this w...

  • Article
  • Open Access
584 Views
10 Pages

Preoperative HALP Score as a Marker of Tumor Aggressiveness and Survival in Surgically Treated Soft Tissue Sarcoma: A Retrospective Cohort Study

  • Hüseyin Pülat,
  • Oğuzhan Söyler,
  • Ünal Öner,
  • Deniz Öztaşan and ,
  • Cüneyt Akyüz and
  • Cemil Yüksel
  • + 1 author+ 0 author

16 April 2026

Objectives: Soft tissue sarcomas (STS) are biologically heterogeneous malignancies with unpredictable clinical behavior. Although tumor size, histological grade, and surgical margin status remain the main determinants of prognosis, additional biomark...

(This article belongs to the Section Oncology)