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Oral and Maxillofacial Surgery: Clinical Advances and Future Directions

A Special Issue of Medicina (ISSN 1648-9144) belonging to the section "Dentistry and Oral Health".

Deadline for manuscript submissions: 25 March 2027 | Viewed by 724

Editors


E-Mail Website
Guest Editor
Department of Maxillofacial Surgery, Medical University of Lodz, 251 Pomorska Str., 92-213 Lodz, Poland
Interests: oral and maxillofacial surgery; implants; bone regeneration; texture analysis; bone augmentation; traumatology; custom made temporomandibular joint replacements; maxillofacial individual implants; head and neck oncology
Special Issues, Collections and Topics in MDPI journals
*
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Guest Editor
Department of Maxillofacial Surgery, Medical University of Lodz, 251 Pomorska Str., 92-213 Lodz, Poland
Interests: maxillofacial surgery; traumatology; deformation treatment; head and neck oncology; infections treatment; human orbital reconstructions; mandibular condyle fixing material; custom-made temporomandibular joint replacements; bone substitute materials; implantology; surgery-first facial deformation algorithm
* We dedicate this Special Issue to the memory of our editor, Prof. Dr. Marcin Kozakiewicz, who passed away while it remains in progress.
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

This Special Issue, ‘Oral and Maxillofacial Surgery: Clinical Advances and Future Directions’, highlights the latest developments, innovative techniques, and emerging trends shaping the field. It brings together cutting-edge research and clinical insights addressing the full spectrum of oral and maxillofacial surgery, from trauma management and reconstructive procedures to implantology, oncologic surgery, and digital innovations such as 3D printing and artificial intelligence.

Emphasis is placed on interdisciplinary approaches that integrate surgical expertise with biomedical engineering, regenerative medicine, and precision diagnostics. The Issue also explores challenges in postoperative care, complication management, and patient-centered outcomes. By showcasing both established and experimental methodologies, this collection aims to advance clinical practice and inspire future research directions. It serves as a comprehensive resource for surgeons, clinicians, and researchers committed to improving patient outcomes and shaping the next generation of oral and maxillofacial surgical care.

Dr. Tomasz Wach
Prof. Dr. Marcin Kozakiewicz
Guest Editors

Manuscript Submission Information

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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • oral and maxillofacial surgery
  • trauma management
  • reconstructive procedures
  • implantology
  • oncologic surgery
  • digital innovations
  • 3D printing
  • artificial intelligence
  • cutting-edge research
  • RTG analysis
  • diagnostics
  • texture analyses
  • anatomy

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Published Papers (1 paper)

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15 pages, 1951 KB  
Systematic Review
The Clinical Effectiveness of Platelet-Rich Fibrin in Post-Extraction Healing: A Systematic Review of Randomized Controlled Trials
by Liene Janaite, Irina Vasilcenko, Ingrida Cema and Ieva Bagante
Medicina 2026, 62(9), 1672; https://doi.org/10.3390/medicina62091672 - 31 Aug 2026
Viewed by 270
Abstract
Background and Objectives: Platelet-rich fibrin (PRF) has been widely investigated as a biological material to enhance healing after tooth extraction; however, its clinical effectiveness remains uncertain. This systematic review evaluates the available evidence on its effectiveness in post-extraction socket management. Materials and [...] Read more.
Background and Objectives: Platelet-rich fibrin (PRF) has been widely investigated as a biological material to enhance healing after tooth extraction; however, its clinical effectiveness remains uncertain. This systematic review evaluates the available evidence on its effectiveness in post-extraction socket management. Materials and Methods: A literature search was conducted across eight electronic databases for English-language studies published between 2015 and 2025. Only randomized controlled trials, including parallel-group randomized trials and randomized split-mouth trials, involving PRF with a control group were considered. The methodological quality of the included studies was assessed using the Cochrane Risk of Bias tool (RoB 1). Due to substantial clinical heterogeneity in PRF preparation protocols, outcome measures, and follow-up periods, a narrative synthesis was performed instead of a meta-analysis. Results: A total of 174 records were identified, of which 9 studies met the inclusion criteria. The methodological quality of the studies included was evaluated to assess the risk of bias, in accordance with the recommendations of the Cochrane Handbook for Systematic Reviews of Interventions. Overall, 394 patients underwent 817 tooth extractions: 414 sockets were treated with different types of PRF, 251 were left to heal after suturing, and 143 were filled with a hemostatic sponge prior to suturing. Conclusions: PRF demonstrated superior outcomes in soft tissue healing and radiographic new bone density, although no statistically significant differences were observed in other parameters. Therefore, the available evidence does not allow us to draw definitive conclusions regarding the clinical effectiveness of PRF for socket filling after tooth extraction. The literature indicates that it may promote soft and hard tissue healing and reduce pain, swelling, and the risk of alveolar osteitis; however, evidence regarding its therapeutic effect on alveolar socket healing remains contradictory. Full article
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