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86 Results Found

  • Article
  • Open Access
1 Citations
1,703 Views
15 Pages

Local Orientation Transitions to a Lying Helix State in Negative Dielectric Anisotropy Cholesteric Liquid Crystal

  • Ivan V. Simdyankin,
  • Artur R. Geivandov,
  • Irina V. Kasyanova and
  • Serguei P. Palto

13 October 2024

Orientation transitions in a cholesteric liquid crystal (CLC) layer with negative dielectric anisotropy, under the influence of a non-uniform spatially periodic electric field created using a planar system of interdigitated electrodes, were studied e...

  • Article
  • Open Access
30 Citations
6,093 Views
25 Pages

Sustainable Milling of Ti-6Al-4V: Investigating the Effects of Milling Orientation, Cutter′s Helix Angle, and Type of Cryogenic Coolant

  • Asif Iqbal,
  • Hazwani Suhaimi,
  • Wei Zhao,
  • Muhammad Jamil,
  • Malik M Nauman,
  • Ning He and
  • Juliana Zaini

17 February 2020

Ti-6Al-4V, the most commonly used alloy of titanium, possesses excellent mechanical properties and corrosion resistance, which is the prime reason for the continual rise in its industrial demand worldwide. The extraordinary mechanical properties of t...

  • Article
  • Open Access
1 Citations
1,880 Views
18 Pages

PolSAR Image Classification by Introducing POA and HA Variances

  • Zeying Lan,
  • Yang Liu,
  • Jianhua He and
  • Xin Hu

11 September 2023

A polarimetric synthetic aperture radar (PolSAR) has great potential in ground target classification. However, current methods experience difficulties in separating forests and buildings, especially oriented buildings. To address this issue, inspired...

  • Article
  • Open Access
7 Citations
3,440 Views
11 Pages

8 November 2021

The introduction of α-helical structure with a specific helix–helix interaction into an amphipathic molecule enables the determination of the molecular packing in the assembly and the morphological control of peptide assemblies. We previously reporte...

  • Article
  • Open Access
6 Citations
3,734 Views
15 Pages

Measuring Entrepreneurial Orientation of University Employees in Developing Countries Using the ENTRE-U Scale

  • Jovana Tatarski,
  • Sandra Brkanlić,
  • Javier Sanchez Garcia,
  • Edgar Breso Esteve,
  • Ivana Brkić,
  • Marko Petrović and
  • Andrea Okanović

27 October 2020

This research examines the difference in the level of entrepreneurial orientation among university employees within the European Union compared to university employees in non-EU countries. The EU Member States included in the research are the Republi...

  • Article
  • Open Access
13 Citations
3,913 Views
13 Pages

Entrepreneurial Orientation of Public Universities in Republic of Serbia-Empirical Study

  • Mirjana Cvijić,
  • Jovana Tatarski,
  • Ivana Katić,
  • Aleksandar Vekić and
  • Jelena Borocki

13 March 2019

This study explores the impact of entrepreneurial orientation on the activities of state universities in the Republic of Serbia. Using the ENTRE-U scale, the researchers have graded the entrepreneurial orientation (EO) of the employees at state unive...

  • Article
  • Open Access
4 Citations
3,169 Views
17 Pages

11 February 2020

Charged and aromatic amino acid residues, being enriched toward the terminals of membrane-spanning helices in membrane proteins, help to stabilize particular transmembrane orientations. Among them, histidine is aromatic and can be positively charge a...

  • Article
  • Open Access
3 Citations
6,288 Views
21 Pages

8 July 2014

This paper improves van Zyl’s Nonnegative Eigenvalue Decomposition (NNED). Orientation angle compensation and helix scattering are introduced to the decomposition. The volume scattering parameters that explain the most cross-polarized power are selec...

  • Article
  • Open Access
12 Citations
3,022 Views
13 Pages

8 September 2019

Waveguide optical properties of a cholesteric liquid crystal (CLC) layer with a deformed lying helix (DLH) have been studied by numerical simulations using the finite difference time domain method. The DLH structure, when the helix’s axis is or...

  • Article
  • Open Access
7 Citations
3,787 Views
16 Pages

Molecular Modeling for Structural Insights Concerning the Activation Mechanisms of F1174L and R1275Q Mutations on Anaplastic Lymphoma Kinase

  • Cheng-Han Jiang,
  • Chong-Xian Huang,
  • Ya-Jyun Chen,
  • Yu-Chung Chuang,
  • Bo-Yen Huang and
  • Chia-Ning Yang

Anaplastic lymphoma kinase (ALK) is a receptor tyrosine kinase involved in various cancers. In its basal state, the structure of ALK is in an autoinhibitory form stabilized by its A-loop, which runs from the N-lobe to the C-lobe of the kinase. Specif...

  • Article
  • Open Access
1 Citations
2,599 Views
31 Pages

21 July 2022

Eric Lord has observed: “In nature, helical structures arise when identical structural subunits combine sequentially, the orientational and translational relation between each unit and its predecessor remaining constant.” This paper prove...

  • Article
  • Open Access
4 Citations
2,510 Views
8 Pages

18 August 2022

The lack of tools particularly designed for the quantification of the fiber morphology in nonwovens, especially the multi-level structured fibers, is the main reason for the limited research studies on the establishment of realistic nonwoven structur...

  • Article
  • Open Access
7 Citations
3,710 Views
14 Pages

Verification of the Saccharina japonica Translocon Tic20 and its Localization in the Chloroplast Membrane in Diatoms

  • Zhihang Chen,
  • Xiuliang Wang,
  • Shuang Li,
  • Jianting Yao,
  • Zhanru Shao and
  • Delin Duan

16 August 2019

Tic20 is an important translocon protein that plays a role in protein transport in the chloroplast. The sequence of Tic20 was determined in the lower brown alga Saccharina japonica. Structural analysis of SjTic20 revealed a noncanonical structure con...

  • Article
  • Open Access
9 Citations
4,071 Views
15 Pages

21 January 2022

The antimicrobial peptide magainin 2 (M2) interacts with and induces structural damage in bacterial cell membranes. Although extensive biophysical studies have revealed the interaction mechanism between M2 and membranes, the mechanism of membrane-med...

  • Article
  • Open Access
12 Citations
3,669 Views
20 Pages

The Mechanism of Action of SAAP-148 Antimicrobial Peptide as Studied with NMR and Molecular Dynamics Simulations

  • Morgane Adélaïde,
  • Evgeniy Salnikov,
  • Francisco Ramos-Martín,
  • Christopher Aisenbrey,
  • Catherine Sarazin,
  • Burkhard Bechinger and
  • Nicola D’Amelio

Background: SAAP-148 is an antimicrobial peptide derived from LL-37. It exhibits excellent activity against drug-resistant bacteria and biofilms while resisting degradation in physiological conditions. Despite its optimal pharmacological properties,...

  • Article
  • Open Access
13 Citations
3,854 Views
16 Pages

27 August 2019

The triple helix (university-industry-government) is a dynamic cooperation model in the area of regional innovation. With the application of this model, the authors aim to address the mechanism of how multiple participants affect innovation efficienc...

  • Article
  • Open Access
1 Citations
1,217 Views
11 Pages

Anomalous Spectral Shift of o-Modes in Multilayer Photonic Structure Induced by Homeotropic–Homeoplanar Transition in Chiral–Nematic Defect Layer

  • Vladimir A. Gunyakov,
  • Vitaly S. Sutormin,
  • Ivan V. Timofeev,
  • Vasily F. Shabanov and
  • Victor Ya. Zyryanov

22 August 2023

A chiral nematic is embedded between multilayer mirrors to obtain voltage-inducible polarized resonance spectra. Initially, the nematic director is uniformly oriented perpendicular to the mirrors’ surfaces because the chiral nematic helix is co...

  • Article
  • Open Access
5 Citations
3,225 Views
19 Pages

Investigation of Helix-Pultruded CFRP Rebar Geometry Variants for Carbon-Reinforced Concrete Structures

  • Daniel Wohlfahrt,
  • Hannes Franz Maria Peller,
  • Steffen Müller,
  • Niels Modler and
  • Viktor Mechtcherine

3 August 2023

Carbon concrete is a new, promising class of materials in the construction industry. This corrosion-resistant reinforcement material leads to a reduction in the concrete cover required for medial shielding. This enables lean construction and the cons...

  • Article
  • Open Access
3 Citations
2,482 Views
16 Pages

Helical versus Flat Bis-Ferrocenyl End-Capped Peptides: The Influence of the Molecular Skeleton on Redox Properties

  • Saverio Santi,
  • Barbara Biondi,
  • Roberta Cardena,
  • Annalisa Bisello,
  • Renato Schiesari,
  • Silvia Tomelleri,
  • Marco Crisma and
  • Fernando Formaggio

19 September 2022

Despite the fact that peptide conjugates with a pendant ferrocenyl (Fc) have been widely investigated, bis-ferrocenyl end-capped peptides are rarely synthetized. In this paper, in addition to the full characterization of the Fc-CO-[L-Dap(Boc)]n-NH-Fc...

  • Article
  • Open Access
10 Citations
3,277 Views
12 Pages

Voltage Sensing in Bacterial Protein Translocation

  • Denis G. Knyazev,
  • Roland Kuttner,
  • Ana-Nicoleta Bondar,
  • Mirjam Zimmerman,
  • Christine Siligan and
  • Peter Pohl

3 January 2020

The bacterial channel SecYEG efficiently translocates both hydrophobic and hydrophilic proteins across the plasma membrane. Translocating polypeptide chains may dislodge the plug, a half helix that blocks the permeation of small molecules, from its p...

  • Article
  • Open Access
37 Citations
10,133 Views
24 Pages

Alpha-Bulges in G Protein-Coupled Receptors

  • Rob Van der Kant and
  • Gert Vriend

6 May 2014

Agonist binding is related to a series of motions in G protein-coupled receptors (GPCRs) that result in the separation of transmembrane helices III and VI at their cytosolic ends and subsequent G protein binding. A large number of smaller motions als...

  • Article
  • Open Access
8 Citations
5,694 Views
21 Pages

13 July 2019

The interaction of antigenic peptides (p) and major histocompatibility complexes (pMHC) with T-cell receptors (TCR) is one of the most important steps during the immune response. Here we present a molecular dynamics simulation study of bound and unbo...

  • Article
  • Open Access
2 Citations
4,320 Views
20 Pages

NMR Structure of the FIV gp36 C-terminal Heptad Repeat and Membrane-Proximal External Region

  • Manuela Grimaldi,
  • Michela Buonocore,
  • Mario Scrima,
  • Ilaria Stillitano,
  • Gerardino D’Errico,
  • Angelo Santoro,
  • Giuseppina Amodio,
  • Daniela Eletto,
  • Antonio Gloria and
  • Teresa Russo
  • + 5 authors

Feline immunodeficiency virus (FIV), a lentivirus causing an immunodeficiency syndrome in cats, represents a relevant model of pre-screening therapies for human immunodeficiency virus (HIV). The envelope glycoproteins gp36 in FIV and gp41 in HIV medi...

  • Article
  • Open Access
1,334 Views
24 Pages

26 September 2025

This study focuses on tourist-oriented urban historic districts. In recent years, many such districts have experienced commercial intensification and homogenization, placing pressure on sustainable development. The prior work is largely descriptive a...

  • Article
  • Open Access
6 Citations
4,437 Views
15 Pages

Engineering the Uniform Lying Helical Structure in Chiral Nematic Liquid Crystals: From Morphology Transition to Dimension Control

  • Zhixuan Jia,
  • Tejal Pawale,
  • Guillermo I. Guerrero-García,
  • Sid Hashemi,
  • José A. Martínez-González and
  • Xiao Li

12 April 2021

Chiral nematic liquid crystals (CLCs), with a unique helix structure, have attracted immense recognition over the last few decades owing to the abundant presence in natural phenomena and their diverse applications. However, the optical properties of...

  • Article
  • Open Access
7 Citations
2,952 Views
11 Pages

A Biallelic Truncating Variant in the TPR Domain of GEMIN5 Associated with Intellectual Disability and Cerebral Atrophy

  • Nazia Ibrahim,
  • Shagufta Naz,
  • Francesca Mattioli,
  • Nicolas Guex,
  • Saima Sharif,
  • Afia Iqbal,
  • Muhammad Ansar and
  • Alexandre Reymond

13 March 2023

GEMIN5 is a multifunctional RNA-binding protein required for the assembly of survival motor neurons. Several bi-allelic truncating and missense variants in this gene are reported to cause a neurodevelopmental disorder characterized by cerebellar atro...

  • Article
  • Open Access
9 Citations
4,681 Views
19 Pages

Bone is a highly hierarchical complex structure that consists of organic and mineral components represented by collagen molecules (CM) and hydroxyapatite crystals (HAC), respectively. The nanostructure of bone can significantly affect its mechanical...

  • Article
  • Open Access
2 Citations
1,730 Views
27 Pages

Experimental Analysis of Effect of Machined Material on Cutting Forces during Drilling

  • Josef Sklenička,
  • Jan Hnátík,
  • Jaroslava Fulemová,
  • Miroslav Gombár,
  • Alena Vagaská and
  • Aneta Jirásko

6 June 2024

Current research studies devoted to cutting forces in drilling are oriented toward predictive model development, however, in the case of mechanistic models, the material effect on the drilling process itself is mostly not considered. This research st...

  • Article
  • Open Access
31 Citations
12,080 Views
25 Pages

30 August 2019

At the European Union (EU) level, innovation matter is acknowledged as crucial for progress and sustainability. Related policy action is materialized through Horizon Europe, the 9th Framework Program (FP) for research and development (R&D). The p...

  • Article
  • Open Access
8 Citations
4,421 Views
25 Pages

Toll-like receptor 3 (TLR3) provides the host with antiviral defense by initiating an immune signaling cascade for the production of type I interferons. The X-ray structures of isolated TLR3 ectodomain (ECD) and transmembrane (TM) domains have been r...

  • Article
  • Open Access
14 Citations
4,292 Views
8 Pages

How Resources of Universities influence Industry Cooperation

  • Gyeong Min Nam,
  • Dae Geon Kim and
  • Sang Ok Choi

In Korea, cooperation between university and company is mainly encouraged by government policy as the Triple Helix’s statist model. Since 2003, the government started a variety of university financial support program, and in 2014, it reached to...

  • Feature Paper
  • Article
  • Open Access
8 Citations
5,817 Views
25 Pages

14 November 2017

Membrane-interacting proteins are polyphilic polymers that engage in dynamic protein–protein and protein–lipid interactions while undergoing changes in conformation, orientation and binding interfaces. Predicting the sites of interactions between suc...

  • Article
  • Open Access
14 Citations
4,124 Views
15 Pages

19 August 2021

DNA is a polymeric macromolecule that can display a variety of backbone conformations. While the classical B-DNA is a right-handed double helix, Z-DNA is a left-handed helix with a zig-zag orientation. The Z conformation depends upon the base sequenc...

  • Article
  • Open Access
1 Citations
2,915 Views
23 Pages

8 December 2021

Catalytic MATα1 subunits associate into kinetically distinct homo-dimers (MAT III) and homo-tetramers (MAT I) that synthesize S-adenosylmethionine in the adult liver. Pathological reductions in S-adenosylmethionine levels correlate with MAT III...

  • Article
  • Open Access
17 Citations
6,397 Views
11 Pages

Optically Controllable Linear-Polarization Rotator Using Chiral-Azobenzene-Doped Liquid Crystals

  • Cheng-Kai Liu,
  • Chian-Yu Chiu,
  • Stephen M. Morris,
  • Min-Cheng Tsai,
  • Chii-Chang Chen and
  • Ko-Ting Cheng

13 November 2017

A linear-polarization rotator based on the optically tunable pitch of chiral-azobenzene-doped liquid crystals (CAdLCs) has been investigated. It is shown that the orientation of linearly polarized (LP) light can be optically tuned using CAdLCs and th...

  • Article
  • Open Access
35 Citations
9,437 Views
18 Pages

19 March 2013

Protein misfolding and aggregation cause serious degenerative diseases, such as Alzheimer’s and type II diabetes. Human islet amyloid polypeptide (hIAPP) is the major component of amyloid deposits found in the pancreas of type II diabetic patients. I...

  • Article
  • Open Access
14 Citations
5,321 Views
23 Pages

4 September 2019

The human cytochrome P450 (CYP) 2C9 and 2C19 enzymes are two highly similar isoforms with key roles in drug metabolism. They are anchored to the endoplasmic reticulum membrane by their N-terminal transmembrane helix and interactions of their cytoplas...

  • Article
  • Open Access
17 Citations
5,739 Views
33 Pages

Towards Citizen Co-Created Public Service Apps

  • Mikel Emaldi,
  • Unai Aguilera,
  • Diego López-de-Ipiña and
  • Jorge Pérez-Velasco

2 June 2017

WeLive project’s main objective is about transforming the current e-government approach by providing a new paradigm based on a new open model oriented towards the design, production and deployment of public services and mobile apps based on the colla...

  • Article
  • Open Access
1 Citations
3,641 Views
19 Pages

13 November 2020

By introducing a suitable renormalization process, the charge carrier and phonon dynamics of a double-stranded helical DNA molecule are expressed in terms of an effective Hamiltonian describing a linear chain, where the renormalized transfer integral...

  • Article
  • Open Access
5 Citations
3,133 Views
11 Pages

Polymer-Dispersed Cholesteric Liquid Crystal under Homeotropic Anchoring: Electrically Induced Structures with λ1/2-Disclination

  • Anna P. Gardymova,
  • Mikhail N. Krakhalev,
  • Vladimir Yu. Rudyak,
  • Vadim A. Barbashov and
  • Victor Ya. Zyryanov

2 April 2022

Orientational structures of polymer-dispersed cholesteric liquid crystal under homeotropic anchoring and their transformations under the action of an electric field are studied. The switching of cholesteric droplets between different topological stat...

  • Article
  • Open Access
39 Citations
3,789 Views
18 Pages

13 May 2021

When the use of optical images is not practical due to cloud cover, Synthetic Aperture Radar (SAR) imagery is a preferred alternative for monitoring coastal wetlands because it is unaffected by weather conditions. Polarimetric SAR (PolSAR) enables th...

  • Feature Paper
  • Article
  • Open Access
49 Citations
10,393 Views
26 Pages

10 February 2020

This paper discusses the need for societal innovation as a systemic form of innovation for sustainable development. Sustainable development requires collective action from stakeholders in the form of system building activities, which in its turn req...

  • Article
  • Open Access
9 Citations
3,568 Views
19 Pages

13 February 2020

The fluorescent base guanine analog, 8-vinyl-deoxyguanosine (8vdG), is studied in solution using a combination of optical spectroscopies, notably femtosecond fluorescence upconversion and quantum chemical calculations, based on time-dependent density...

  • Article
  • Open Access
7 Citations
4,231 Views
19 Pages

Polarization Control with Helical Metasurfaces

  • Ihar Faniayeu,
  • Viktar Asadchy and
  • Ivan Fanyaev

20 August 2020

The ability to fully control the polarization of light using chiral metadevices has drawn considerable attention in various applications of integrated photonics, communication systems, and life sciences. In this work, we propose a comprehensive appro...

  • Communication
  • Open Access
8 Citations
3,327 Views
9 Pages

26 February 2022

We report the result of an accurate calculation of optical transmission of a light beam traveling along the helix direction of a heliconical cholesteric liquid crystal when the light intensity is affecting the director orientation by an effective opt...

  • Feature Paper
  • Article
  • Open Access
8 Citations
4,752 Views
17 Pages

1 February 2023

Climate change, energy transition needs and the current energy crisis have prompted cities to implement far-reaching changes in public energy supply. The present paper seeks to map out the conditions for sustainable energy provision and use, with a p...

  • Article
  • Open Access
1 Citations
2,388 Views
15 Pages

10 October 2023

In recent years, transport policy has strongly been oriented to develop more inclusive cities and to design mobility services aligned to specific users’ needs. In an attempt to guarantee an adequate level of accessibility, especially to vulnera...

  • Article
  • Open Access
21 Citations
4,590 Views
23 Pages

A Hierarchical Extension of General Four-Component Scattering Power Decomposition

  • Sinong Quan,
  • Deliang Xiang,
  • Boli Xiong,
  • Canbin Hu and
  • Gangyao Kuang

18 August 2017

The overestimation of volume scattering (OVS) is an intrinsic drawback in model-based polarimetric synthetic aperture radar (PolSAR) target decomposition. It severely impacts the accuracy measurement of scattering power and leads to scattering mechan...

  • Article
  • Open Access
11 Citations
4,180 Views
27 Pages

26 October 2022

This paper presents a robust proportional derivative adaptive nonsingular finite-time synergetic tracking control (PDAFS) for a parallel Delta robot system. First, a finite-time synergetic controller combined with a proportional derivative (PD) contr...

  • Article
  • Open Access
16 Citations
6,960 Views
24 Pages

Nanoconfinement-Induced Structures in Chiral Liquid Crystals

  • Michael Melle,
  • Madlona Theile,
  • Carol K. Hall and
  • Martin Schoen

28 August 2013

We employ Monte Carlo simulations in a specialized isothermal-isobaric and in the grand canonical ensemble to study structure formation in chiral liquid crystals as a function of molecular chirality. Our model potential consists of a simple Lennard-J...

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