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5,363 Results Found

  • Article
  • Open Access
8 Citations
3,609 Views
13 Pages

Intermediate Repeat Expansion in the ATXN2 Gene as a Risk Factor in the ALS and FTD Spanish Population

  • Daniel Borrego-Hernández,
  • Juan Francisco Vázquez-Costa,
  • Raúl Domínguez-Rubio,
  • Laura Expósito-Blázquez,
  • Elena Aller,
  • Ariadna Padró-Miquel,
  • Pilar García-Casanova,
  • María J. Colomina,
  • Cristina Martín-Arriscado and
  • Alberto García-Redondo
  • + 4 authors

Intermediate CAG expansions in the gene ataxin-2 (ATXN2) are a known risk factor for ALS, but little is known about their role in FTD risk. Moreover, their contribution to the risk and phenotype of patients might vary in populations with different ge...

  • Article
  • Open Access
1 Citations
2,489 Views
30 Pages

5 June 2025

The increasing complexity of data ecosystems demands advanced methodologies for systematic privacy risk assessment. This work introduces two complementary metrics—the privacy risk expansion factor (PREF) and the privacy exposure index (PEI)&mda...

  • Article
  • Open Access
5 Citations
2,707 Views
30 Pages

20 January 2023

This paper focused on the performance monitoring and modeling of a 6.0 kW, 2000 L hybrid direct expansion solar assisted heat pump (DX-SAHP) water heater used for the production of hot water in a university students’ accommodation with 123 fema...

  • Article
  • Open Access
5 Citations
4,931 Views
23 Pages

Conservation and Expansion of Transcriptional Factor Repertoire in the Fusarium oxysporum Species Complex

  • Houlin Yu,
  • He Yang,
  • Sajeet Haridas,
  • Richard D. Hayes,
  • Hunter Lynch,
  • Sawyer Andersen,
  • Madison Newman,
  • Gengtan Li,
  • Domingo Martínez-Soto and
  • Li-Jun Ma
  • + 4 authors

15 March 2023

The Fusarium oxysporum species complex (FOSC) includes both plant and human pathogens that cause devastating plant vascular wilt diseases and threaten public health. Each F. oxysporum genome comprises core chromosomes (CCs) for housekeeping functions...

  • Review
  • Open Access
5 Citations
5,679 Views
20 Pages

A Comprehensive Review of Urban Expansion and Its Driving Factors

  • Ming Li,
  • Yongwang Cao,
  • Jin Dai,
  • Jianxin Song and
  • Mengyin Liang

26 July 2025

Urban expansion has a profound impact on both society and the environment. In this study, VOSviewer 1.6.16 and CiteSpace 6.3.R1 were used to conduct a bibliometric analysis of 2987 articles published during the period of 1992–2022 from the Web...

  • Article
  • Open Access
42 Citations
5,987 Views
29 Pages

25 October 2019

Urban expansion is one of the most dramatic forms of land transformation in the world and it is one of the greatest challenges in achieving sustainable development in the 21st century. Previous studies analyzed urbanization patterns in areas with rap...

  • Article
  • Open Access
7 Citations
2,600 Views
23 Pages

Spatio-Temporal Features and Influencing Factors of Homesteads Expansion at Village Scale

  • Jie Zhang,
  • Shengping Liu,
  • Zijuan Zhao,
  • Bin Li,
  • Beilei Fan and
  • Guomin Zhou

1 October 2022

The current research on the change of homesteads has rarely combined spatial information, and no expansion research has been found with a scale as detailed as the level of the homestead plots. Understanding the changing rules of homesteads expansion...

  • Article
  • Open Access
62 Citations
8,211 Views
17 Pages

Urban Expansion Simulation Based on Various Driving Factors Using a Logistic Regression Model: Delhi as a Case Study

  • Muhammad Salem,
  • Arghadeep Bose,
  • Bashar Bashir,
  • Debanjan Basak,
  • Subham Roy,
  • Indrajit R. Chowdhury,
  • Abdullah Alsalman and
  • Naoki Tsurusaki

28 September 2021

During the last three decades, Delhi has witnessed extensive and rapid urban expansion in all directions, especially in the East South East zone. The total built-up area has risen dramatically, from 195.3 sq. km to 435.1 sq. km, during 1989–2020, whi...

  • Article
  • Open Access
9 Citations
3,979 Views
24 Pages

14 October 2022

Studying the expansion of urban construction land is necessary to promote rational land use and scientific territorial spatial planning. To reveal urban built-up areas, this study uses 1990–2020 Landsat remote sensing images, superimposed with...

  • Article
  • Open Access
2 Citations
1,490 Views
23 Pages

Expansion of Naturally Grown Phyllostachys edulis (Carrière) J. Houzeau Forests into Diverse Habitats: Rates and Driving Factors

  • Juan Wei,
  • Yongde Zhong,
  • Dali Li,
  • Jinyang Deng,
  • Zejie Liu,
  • Shuangquan Zhang and
  • Zhao Chen

23 August 2024

Moso bamboo (Phyllostachys edulis (Carrière) J. Houzeau), which is native to China, is considered to be an invasive species due to its powerful asexual reproductive capabilities that allow it to rapidly spread into neighboring ecosystems and r...

  • Article
  • Open Access
5 Citations
2,470 Views
20 Pages

Studying construction land expansion (CLE) characteristics and driving factors in resource-based cities (RBCs) is important to promote efficient land use and maintain ecological equilibrium in RBCs. This study explores the CLE and its driving factors...

  • Article
  • Open Access
64 Citations
8,307 Views
16 Pages

Exploring Annual Urban Expansions in the Guangdong-Hong Kong-Macau Greater Bay Area: Spatiotemporal Features and Driving Factors in 1986–2017

  • Jie Zhang,
  • Le Yu,
  • Xuecao Li,
  • Chenchen Zhang,
  • Tiezhu Shi,
  • Xiangyin Wu,
  • Chao Yang,
  • Wenxiu Gao,
  • Qingquan Li and
  • Guofeng Wu

13 August 2020

The Guangdong–Hong Kong–Macau Greater Bay Area (GBA) of China is one of the largest bay areas in the world. However, the spatiotemporal characteristics and driving mechanisms of urban expansions in this region are poorly understood. Here...

  • Article
  • Open Access
58 Citations
10,197 Views
14 Pages

The peri-urban area (PUA) of the Greater Cairo Region (GCR) in Egypt has witnessed a rapid urban expansion during the last few years. This urban expansion has led to the loss of wide, areas of agriculture lands and the annexation of many peripheral v...

  • Article
  • Open Access
14 Citations
4,531 Views
15 Pages

10 August 2017

In this paper, built-up land expansion patterns and the associated factors were characterized in urban and non-urban areas across the Wen-Tai region of eastern China. Fractal dimension can be used as a reliable indicator of the complexity of built-up...

  • Article
  • Open Access
9 Citations
3,908 Views
19 Pages

Estimating Carbon Stocks and Biomass Expansion Factors of Urban Greening Trees Using Terrestrial Laser Scanning

  • Linlin Wu,
  • Yongjun Shi,
  • Fanyi Zhang,
  • Yufeng Zhou,
  • Zhentian Ding,
  • Shixin Lv and
  • Lin Xu

31 August 2022

Urban forest carbon sequestration represents an important component of the global forest carbon pool; however, accurate measurements are limited by the inability of existing field stand models to match the specificity of urban greening species. Herei...

  • Article
  • Open Access
1 Citations
2,105 Views
17 Pages

10 October 2021

The Simplified Spherical Harmonic (SPN) approximation was first introduced as a three-dimensional (3D) extension of the plane-geometry Spherical Harmonic (PN) equations. A third order SPN (SP3) solver, recently implemented in the Nodal Expansion Meth...

  • Review
  • Open Access
10 Citations
3,410 Views
16 Pages

Gene expansion is a common phenomenon in plant transcription factor families; however, the underlying molecular mechanisms remain elusive. Examples of gene expansion in transcription factors are found in all eukaryotes. One example is plant nuclear f...

  • Article
  • Open Access
1 Citations
1,785 Views
24 Pages

13 November 2024

A systematic understanding of the spatial-temporal evolution patterns of cultivated land fragmentation (CLF), its driving factors, and its relationship with the expansion of urban and rural construction land is essential for identifying strategies to...

  • Article
  • Open Access
15 Citations
3,628 Views
15 Pages

16 January 2023

Using data from 30 provinces and cities in China from 2005–2018, panel regression models, mediation models, quantile regressions and threshold regressions were used to examine the relationship between graduate student size expansion, innovative...

  • Article
  • Open Access
15 Citations
3,161 Views
41 Pages

28 February 2024

In this study, a series of ester-linked tetracarboxylic dianhydrides (TCDAs) with 2,6-naphthalene-containing longitudinally extended structures consisting of different numbers of aromatic rings (NAr = 6–8) was synthesized to obtain novel modifi...

  • Article
  • Open Access
1 Citations
2,786 Views
22 Pages

The Human Factor in Transmission Network Expansion Planning: The Grid That a Sustainable Energy System Needs

  • Sara Lumbreras,
  • Jesús David Gómez,
  • Erik Francisco Alvarez and
  • Sebastien Huclin

31 May 2022

The decarbonization of the energy sector puts additional pressure on the transmission network. The main cause for this is that renewable sources are often more abundant in geographical areas far away from the main demand centers, so new transmission...

  • Article
  • Open Access
1 Citations
2,778 Views
22 Pages

H3 Acetylation-Induced Basal Progenitor Generation and Neocortex Expansion Depends on the Transcription Factor Pax6

  • Godwin Sokpor,
  • Cemil Kerimoglu,
  • Pauline Antonie Ulmke,
  • Linh Pham,
  • Hoang Duy Nguyen,
  • Beate Brand-Saberi,
  • Jochen F. Staiger,
  • Andre Fischer,
  • Huu Phuc Nguyen and
  • Tran Tuoc

23 January 2024

Enrichment of basal progenitors (BPs) in the developing neocortex is a central driver of cortical enlargement. The transcription factor Pax6 is known as an essential regulator in generation of BPs. H3 lysine 9 acetylation (H3K9ac) has emerged as a cr...

  • Article
  • Open Access
7 Citations
5,255 Views
9 Pages

3 January 2014

By phenomenologically assuming a slow temporal variation of the percent acceleration rate S̈S -1 of the cosmic scale factor S(t), it is shown that the orbit of a local binary undergoes a secular expansion. To first order in the power expansion of S̈S...

  • Article
  • Open Access
211 Views
14 Pages

Anatomical and Transcriptomic Analyses Revealed the Key Genes Associated with Tuber Expansion in Cyperus esculentus L.

  • Xiangge Zhang,
  • Chen Chen,
  • Shan Cheng,
  • Meng Wang,
  • Shufeng Wang,
  • Yi Du,
  • Xiangong Chen,
  • Xin Wang,
  • Chuanjun Zhang and
  • Huiwei Wang
  • + 1 author

23 January 2026

Background: Cyperus esculentus L. is a unique tuber oil crop, in which tuber size directly determines both yield and oil storage capacity. It is crucial to clarify the tuber expansion pattern and explore the key genes associated with tuber expan...

  • Article
  • Open Access
46 Citations
4,602 Views
16 Pages

Expansion of CD4 T Lymphocytes Expressing Interleukin 17 and Tumor Necrosis Factor in Patients with Major Depressive Disorder

  • Miguel Angel Alvarez-Mon,
  • Ana Maria Gómez-Lahoz,
  • Arancha Orozco,
  • Guillermo Lahera,
  • David Diaz,
  • Miguel A. Ortega,
  • Agustin Albillos,
  • Javier Quintero,
  • Enrique Aubá and
  • Melchor Alvarez-Mon
  • + 1 author

19 March 2021

Background: We have investigated the distribution of the Th1, Th2 and Th17 subsets in circulating CD4+ T lymphocytes and their naïve (TN), effector (TE), central (TCM) and effector memory (TEM) activation/differentiation stages in patients with major...

  • Article
  • Open Access
677 Views
27 Pages

Spatiotemporal Trends and Driving Factors of Global Impervious Surface Area Changes from 2001 to 2020

  • Yihan Xia,
  • Yanning Guan,
  • Tao Yang,
  • Jiaqi Qian,
  • Zhishou Wei,
  • Wutao Yao,
  • Rui Deng,
  • Chunyan Zhang and
  • Shan Guo

26 September 2025

The change in impervious surface area (ISA) is an important factor reflecting urban expansion. This study used the global ISA dataset to analyze the spatiotemporal changes in ISA from 2001 to 2020 worldwide, explored the hotspots and patterns of ISA...

  • Article
  • Open Access
6 Citations
2,213 Views
20 Pages

Effect of Sulfate Attack on the Expansion Behavior of Cement-Treated Aggregates

  • Qi Wang,
  • Jiankun Liu,
  • Pengcheng Wang,
  • Jiangxin Liu and
  • Mingzhi Sun

29 January 2024

The expansion induced by sulfate attack on cement-treated aggregates (SACA) is a well-known problem that can be solved. It causes obvious heaves in road bases and railway subgrades. In this paper, the effects of the sodium sulfate content, cement con...

  • Article
  • Open Access
252 Views
26 Pages

Quantifying Urban Expansion and Its Driving Forces in the Indus River Basin Using Multi-Source Spatial Data

  • Wenfei Luan,
  • Jingyao Zhu,
  • Wensheng Wang,
  • Chunfeng Ma,
  • Qingkai Liu,
  • Yu Wang,
  • Haitao Jing,
  • Bing Wang and
  • Hui Li

14 January 2026

Urban expansion and its driving factors are frequently analyzed within administrative regions to inform regional urban planning, yet such analyses often fall short at the natural basin scale (referring to the spatial extent defined by hydrological dr...

  • Article
  • Open Access
3 Citations
1,901 Views
18 Pages

14 September 2023

Based on nighttime light data from 2000, 2005, 2010, 2015 and 2020, the urban built-up area of 90 prefecture-level cities in the Yellow River Basin was extracted, and the urban spatial expansion characteristics of 90 prefecture-level cities were expl...

  • Article
  • Open Access
1 Citations
1,389 Views
18 Pages

6 July 2024

A non-periodic “step-like” variation in displacement is exhibited owing to the repeated instability of expansive soil landslides. The dynamic prediction of deformation for expansive soil landslides has become a challenge in actual enginee...

  • Article
  • Open Access
31 Citations
4,161 Views
16 Pages

7 February 2021

Rural residential land is the main space of a farmer’s life, rural culture, and social relations. Prior research of rural residential land has focused more on its evolvement in plain and traditional agricultural areas. Yet, there is no clear picture...

  • Article
  • Open Access
1 Citations
1,403 Views
15 Pages

14 March 2025

Cone penetration test often uses the cone factor to calculate the undrained shear strength of silty clay base on the cone tip resistance data, but the accurate determination of the cone factor is challenging due to its wide range of values. This stud...

  • Article
  • Open Access
1 Citations
3,013 Views
12 Pages

Spatiotemporal Analysis of Urban Expansion in Beijing, China

  • Jing Zhang,
  • Jichang Han,
  • Yanan Li and
  • Na Lei

14 October 2024

Using Landsat TM/OLI remote sensing images and social statistical data from 1995, 2000, 2005, 2010, 2015, and 2020, construction land information in Beijing’s main urban area was extracted with ArcGIS 10.4.1 and other software. Based on calcula...

  • Article
  • Open Access
4 Citations
2,248 Views
18 Pages

8 February 2025

It is well established that China’s rapid urban expansion has led to a substantial loss of cropland. However, few studies have examined how different urban expansion patterns contribute to cropland consumption, which has hindered the formulatio...

  • Article
  • Open Access
5 Citations
3,013 Views
15 Pages

19 December 2023

The purpose of this paper is to compare the differential impact of Taiwan High-speed Railway (T-HSR) and Hainan East Ring High-speed Railway (HER-HSR) stations on the surrounding construction land expansion, reveal the underlying institutional reason...

  • Article
  • Open Access
7 Citations
3,279 Views
14 Pages

Comparative Transcriptome Profiling Reveals the Genes Involved in Storage Root Expansion in Sweetpotato (Ipomoea batatas (L.) Lam.)

  • Weihan Song,
  • Hui Yan,
  • Meng Ma,
  • Meng Kou,
  • Chen Li,
  • Wei Tang,
  • Yicheng Yu,
  • Qixian Hao,
  • Thanhliem Nguyen and
  • Qiang Li
  • + 5 authors

27 June 2022

Sweetpotato (Ipomoea batatas (L.) Lam.) is recognized as one of the most important root crops in the world by the Food and Agriculture Organization of the United Nations. The yield of sweetpotato is closely correlated with the rate of storage root (S...

  • Article
  • Open Access
6 Citations
2,315 Views
17 Pages

12 July 2023

Escalating urban issues in Beijing call for comprehensive exploration of urban construction land expansion towards the goal of carbon neutrality. Firstly, urban construction land in Beijing during the period 2005–2020 was accurately detected us...

  • Article
  • Open Access
16 Citations
3,219 Views
34 Pages

18 September 2024

The rapid increase in population and economic activities has greatly influenced land use and spatial development. In urban agglomerations where socioeconomic activities are densely concentrated, the clash between ecological protection and economic gr...

  • Article
  • Open Access
2 Citations
1,750 Views
19 Pages

24 August 2024

Panax ginseng taproot serves as a crucial storage organ and constitutes a significant component of Chinese herbal medicine. In China, ginseng is cultivated using two primary methods: under-forest planting and farmland planting. These methods create d...

  • Article
  • Open Access
15 Citations
4,163 Views
15 Pages

The expansion and evolution of urban areas are the most perceptible manifestations of the transformation of the urban spatial form. This study uses remote sensing images of Nanjing from 2001, 2006, 2011, 2016, and 2021, along with socio-economic data...

  • Article
  • Open Access
1,513 Views
28 Pages

20 September 2025

Parkinson’s disease (PD), the second most common neurodegenerative disorder globally, has a notably high prevalence in Sweden (136/105). Although monogenic forms represent only a small subset of PD cases, several genetic factors—including...

  • Article
  • Open Access
31 Citations
6,806 Views
20 Pages

Expansion of Impervious Surfaces and Their Driving Forces in Highly Urbanized Cities in Kyrgyzstan

  • Gulkaiyr Omurakunova,
  • Anming Bao,
  • Wenqiang Xu,
  • Eldiiar Duulatov,
  • Liangliang Jiang,
  • Peng Cai,
  • Farkhod Abdullaev,
  • Vincent Nzabarinda,
  • Khaydar Durdiev and
  • Makhabat Baiseitova

The expansion of urban areas due to population increase and economic expansion creates demand and depletes natural resources, thereby causing land use changes in the main cities. This study focuses on land cover datasets to characterize impervious su...

  • Article
  • Open Access
4 Citations
2,972 Views
15 Pages

With the continuous intensification of global climate warming, the carbon cycle has become the focus of global climate change, and the calculation and value evaluation of forest carbon reserves is a key link in promoting the global carbon cycle syste...

  • Article
  • Open Access
43 Citations
7,598 Views
19 Pages

19 September 2021

The current glacial lake datasets in the High Mountain Asia (HMA) region still need to be improved because their boundary divisions in the land–water transition zone are not precisely delineate, and also some very small glacial lakes have been lost d...

  • Review
  • Open Access
7 Citations
6,615 Views
15 Pages

Role of Cytokines and Growth Factors in the Manufacturing of iPSC-Derived Allogeneic Cell Therapy Products

  • Chen-Yuan Kao,
  • Jason A. Mills,
  • Carl J. Burke,
  • Barry Morse and
  • Bruno F. Marques

Cytokines and other growth factors are essential for cell expansion, health, function, and immune stimulation. Stem cells have the additional reliance on these factors to direct differentiation to the appropriate terminal cell type. Successful manufa...

  • Article
  • Open Access
816 Views
18 Pages

Yam (Dioscorea spp.) provides various nutritional and medicinal benefits, including a high starch content, dietary fiber, essential micronutrients, and bioactive compounds. The molecular mechanisms underlying tuber expansion have not yet been clarifi...

  • Communication
  • Open Access
515 Views
17 Pages

3 September 2025

In this article, we study a directed version of Douglas–Rachford splitting method in real Hilbert spaces. By using new, self-contained, and simplified techniques, we prove its weak convergence. The major innovation is that we exploit the firm n...

  • Article
  • Open Access
3 Citations
3,263 Views
7 Pages

14 January 2021

A study on the coefficient of thermal expansion (CTE) of single-wall carbon nanotube (SWCNT)-reinforced nanocomposites is presented in this paper. An interfacial adhesion factor (IAF) is introduced for the purpose of modelling the adhesion between SW...

  • Case Report
  • Open Access
7 Citations
1,187 Views
2 Pages

Use of Recombinant Factor VIIa in Symptomatic Intracerebral Hemorrhage Following Intravenous Thrombolysis

  • Shadi Yaghi,
  • Aya Haggiagi,
  • Ayesha Sherzai,
  • Randolph S. Marshall and
  • Sachin Agarwal

Symptomatic intracerebral hemorrhage (sICH) occurs in up to 7% of stroke patients treated with thrombolytic therapy. There are limited data on the effectiveness of the reversal agents used for intravenous tissue plasminogen activator related intracra...

  • Article
  • Open Access
5 Citations
1,661 Views
21 Pages

4 September 2024

In recent years, China’s urbanization has accelerated, significantly impacting ecosystems and the carbon balance due to changes in urban land use. The spatial patterns of CO2 emissions from urban land are essential for devising strategies to mi...

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