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44 Results Found

  • Article
  • Open Access
2 Citations
3,249 Views
12 Pages

An automated compounding device can be a useful tool for the rapid and accurate production of small batches for personalized medicine as well as for clinical batches. A novel electronic liquid dispensing system (ELDS) was investigated to produce hard...

  • Article
  • Open Access
1 Citations
2,183 Views
17 Pages

Repackaging and Performance Analysis of Implantable Pressure Sensor

  • Liu Cui,
  • Shuangkui Wang,
  • Kai Zhao and
  • Zhisen Si

22 January 2025

In recent years, repackaging technology has been widely used in miniaturized implantable pressure sensors. However, the current packaging structure still has significant problems regarding biocompatibility, environmental adaptability, and measurement...

  • Article
  • Open Access
15 Citations
3,455 Views
16 Pages

Automated Bowel Polyp Detection Based on Actively Controlled Capsule Endoscopy: Feasibility Study

  • Manh Cuong Hoang,
  • Kim Tien Nguyen,
  • Jayoung Kim,
  • Jong-Oh Park and
  • Chang-Sei Kim

12 October 2021

This paper presents an active locomotion capsule endoscope system with 5D position sensing and real-time automated polyp detection for small-bowel and colon applications. An electromagnetic actuation system (EMA) consisting of stationary electromagne...

  • Review
  • Open Access
39 Citations
9,119 Views
20 Pages

Preparation, Properties and Potential of Carrageenan-Based Hard Capsules for Replacing Gelatine: A Review

  • Muhammad Al Rizqi Dharma Fauzi,
  • Pratiwi Pudjiastuti,
  • Arief Cahyo Wibowo and
  • Esti Hendradi

10 August 2021

Intense efforts to develop alternative materials for gelatine as a drug-delivery system are progressing at a high rate. Some of the materials developed are hard capsules made from alginate, carrageenan, hypromellose and cellulose. However, there are...

  • Feature Paper
  • Article
  • Open Access
17 Citations
3,210 Views
22 Pages

Conductive Compartmented Capsules Encapsulating a Bitumen Rejuvenator

  • Amir Tabaković,
  • Joseph Mohan and
  • Aleksandar Karač

3 August 2021

This paper explores the potential use of conductive alginate capsules encapsulating a bitumen rejuvenator as a new extrinsic self-healing asphalt method. The capsules combine two existing self-healing asphalt technologies: (1) rejuvenator encapsulati...

  • Article
  • Open Access
55 Citations
6,574 Views
12 Pages

Optimization of the Calcium Alginate Capsules for Self-Healing Asphalt

  • Shi Xu,
  • Amir Tabaković,
  • Xueyan Liu,
  • Damian Palin and
  • Erik Schlangen

30 January 2019

It has been demonstrated that calcium alginate capsules can be used as an asphalt healing system by pre-placing rejuvenator (healing agent) into the asphalt mix and releasing the rejuvenator on demand (upon cracking). This healing mechanism relies on...

  • Article
  • Open Access
10 Citations
3,052 Views
15 Pages

Development of Submicrocapsules Based on Co-Assembled Like-Charged Silica Nanoparticles and Detonation Nanodiamonds and Polyelectrolyte Layers

  • Konstantin V. Palamarchuk,
  • Tatiana N. Borodina,
  • Anastasia V. Kostenko,
  • Yury M. Chesnokov,
  • Roman A. Kamyshinsky,
  • Natalya P. Palamarchuk,
  • Elena B. Yudina,
  • Elena D. Nikolskaya,
  • Nikita G. Yabbarov and
  • Mariia R. Mollaeva
  • + 1 author

Capsules with shells based on nanoparticles of different nature co-assembled at the interface of liquid phases of emulsion are promising carriers of lipophilic drugs. To obtain such capsules, theoretically using the Derjaguin–Landau–Verwe...

  • Article
  • Open Access
5 Citations
2,098 Views
17 Pages

Tracking and Dynamic Tuning of a Wireless Powered Endoscopic Capsule

  • Lucas Murliky,
  • Gustavo Oliveira,
  • Fernando Rangel de Sousa and
  • Valner João Brusamarello

13 September 2022

This work presents an inductive wireless power transfer system for powering an endoscopy capsule supplying energy to power electronic devices allocated inside a capsule of ≈26.1 mm × 9 mm. A receiver with three coils in quadrature with di...

  • Feature Paper
  • Article
  • Open Access
54 Citations
10,032 Views
16 Pages

Development of a Compact, IoT-Enabled Electronic Nose for Breath Analysis

  • Akira Tiele,
  • Alfian Wicaksono,
  • Sai Kiran Ayyala and
  • James A. Covington

In this paper, we report on an in-house developed electronic nose (E-nose) for use with breath analysis. The unit consists of an array of 10 micro-electro-mechanical systems (MEMS) metal oxide (MOX) gas sensors produced by seven manufacturers. Breath...

  • Article
  • Open Access
5 Citations
2,531 Views
17 Pages

14 June 2023

Melon seed oil (MSO) possesses plenty of long-chain fatty acids (LFCAs, oleic–linoleic acid 90%), remarkable antioxidant activity (DPPH (0.37 ± 0.40 µmol TE/g), ABTS (4.98 ± 0.18 µmol TE/g), FRAP (0.99 ± 0.02 &m...

  • Article
  • Open Access
18 Citations
7,365 Views
15 Pages

23 July 2019

Polyurea (PU) nano-capsules have received voluminous interest in various fields due to their biocompatibility, high mechanical properties, and surface functionality. By incorporating magnetic nanoparticle (MNPs) into the polyurea system, the attribut...

  • Article
  • Open Access
27 Citations
4,453 Views
21 Pages

2 April 2019

Micro-/nanomotors colloidal particles have attracted increasing interest as composite surfactants, owing to the combined advantages of both Janus solid surfactants and micro-/nanomotors. Here we put micro-/nanomotors colloidal particles into hollow p...

  • Article
  • Open Access
4 Citations
1,694 Views
22 Pages

23 December 2011

In the present study, asymmetric membrane capsules (AMCs) with two com-partments were successfully developed for simultaneous delivery of two poorly water-soluble drugs, Atenolol and Amlodipine Besylate, by using solubility modulation approach. Scann...

  • Article
  • Open Access
7 Citations
3,401 Views
16 Pages

Chitosan and Sodium Alginate Implementation as Pharmaceutical Excipients in Multiple-Unit Particulate Systems

  • Martina Čierna,
  • Pavel Mučaji,
  • Miroslava Špaglová,
  • Mária Čuchorová and
  • Oliver Macho

11 July 2022

This study aimed to prepare and evaluate pellets containing acyclovir as a model drug. Pellets were prepared by the extrusion–spheronization process. Aqueous solutions of natural marine polymers (sodium alginate, chitosan) were compared to semi...

  • Article
  • Open Access
16 Citations
7,478 Views
15 Pages

Power Supply Solution for Ultrahigh Speed Hyperloop Trains

  • Marcos Lafoz,
  • Gustavo Navarro,
  • Jorge Torres,
  • Álvaro Santiago,
  • Jorge Nájera,
  • Miguel Santos-Herran and
  • Marcos Blanco

The paper analyses the alternatives for the power supply of a Hyperloop type railway transport. The particular case of the technology of the Spanish company ZELEROS was studied. Based on previous technical specifications related to both the first pro...

  • Article
  • Open Access
20 Citations
4,632 Views
15 Pages

Preparation of Phase Change Microcapsules with the Enhanced Photothermal Performance

  • Sara Tahan Latibari,
  • Jacco Eversdijk,
  • Ruud Cuypers,
  • Vassiliki Drosou and
  • Mina Shahi

16 September 2019

The performance of solar-thermal conversion systems can be improved by incorporation of encapsulated phase change materials. In this study, for the first time, CrodathermTM 60 as a phase change material (PCM) was successfully encapsulated within poly...

  • Perspective
  • Open Access
2,234 Views
5 Pages

Creating Data Standards to Support the Electronic Transmission of Compounded Nonsterile Preparations (CNSPs): Perspectives of a United States Pharmacopeia Expert Panel

  • Richard H. Parrish,
  • Scott Ciarkowski,
  • David Aguero,
  • Sandra Benavides,
  • Donna Z. Bohannon,
  • Roy Guharoy and
  • on behalf of the United States Pharmacopeia Compounded Drug Preparation Information Exchange Expert Panel

29 September 2022

The perspectives of the Compounded Drug Preparation Information Exchange Expert Panel of the United States Pharmacopeia (CDPIE-EP) on the urgent need to create and maintain data standards to support the electronic transmission of an interoperable dat...

  • Article
  • Open Access
32 Citations
4,770 Views
14 Pages

Vinblastine (VBL) is a major chemotherapeutic drug; however, in some cases, it may cause severe side effects in patients with cancer. Designing a novel VBL pharmaceutical formulation is a crucial and emerging concern among researchers for reducing th...

  • Article
  • Open Access
48 Citations
6,189 Views
16 Pages

Fast-Dissolving Nifedipine and Atorvastatin Calcium Electrospun Nanofibers as a Potential Buccal Delivery System

  • Hassa A. Alshaya,
  • Ahmed J. Alfahad,
  • Fatemah M. Alsulaihem,
  • Alhassan H. Aodah,
  • Abdullah A. Alshehri,
  • Fahad A. Almughem,
  • Haya A. Alfassam,
  • Ahmad M. Aldossary,
  • Abdulrahman A. Halwani and
  • Haitham A. Bukhary
  • + 4 authors

Geriatric patients are more likely to suffer from multiple chronic diseases that require using several drugs, which are commonly ingested. However, to enhance geriatric patients’ convenience, the electrospun nanofiber system was previously prov...

  • Article
  • Open Access
45 Citations
8,339 Views
13 Pages

5 January 2020

The mechanical and barrier properties of plant-based enteric polymer films were enhanced by synergistic interactions between binary gum mixtures and adding plasticizers. The results indicated that the best ratio of gellan gum (GG) and xanthan gum (XG...

  • Article
  • Open Access
2 Citations
2,609 Views
18 Pages

Advancements in PCB Components Recognition Using WaferCaps: A Data Fusion and Deep Learning Approach

  • Dmitrii Starodubov,
  • Sebelan Danishvar,
  • Abd Al Rahman M. Abu Ebayyeh and
  • Alireza Mousavi

Microelectronics and electronic products are integral to our increasingly connected world, facing constant challenges in terms of quality, security, and provenance. As technology advances and becomes more complex, the demand for automated solutions t...

  • Article
  • Open Access
1,328 Views
22 Pages

Ionotropic Gelation and Chemical Crosslinking as Tools to Obtain Gellan Gum-Based Beads with Mesalazine

  • Piotr Gadziński,
  • Agnieszka Skotnicka,
  • Natalia Lisiak,
  • Ewa Totoń,
  • Błażej Rubiś,
  • Ewa Florek,
  • Dariusz T. Mlynarczyk,
  • Mirosław Szybowicz,
  • Ewelina Nowak and
  • Tomasz Osmałek

Introduction: Many orally administered drugs are either unstable in the acidic environment of the stomach or cause moderate to severe side effects in the upper gastrointestinal tract (GIT). These limitations can reduce therapeutic efficacy, discourag...

  • Communication
  • Open Access
11 Citations
4,460 Views
15 Pages

Development of an Easy-to-Operate Underwater Raman System for Deep-Sea Cold Seep and Hydrothermal Vent In Situ Detection

  • Qingsheng Liu,
  • Jinjia Guo,
  • Wangquan Ye,
  • Kai Cheng,
  • Fujun Qi,
  • Ronger Zheng,
  • Zhilei Sun and
  • Xilin Zhang

27 July 2021

As a powerful in situ detection technique, Raman spectroscopy is becoming a popular underwater investigation method, especially in deep-sea research. In this paper, an easy-to-operate underwater Raman system with a compact design and competitive sens...

  • Article
  • Open Access
17 Citations
5,385 Views
12 Pages

Impact of Nanocapsules on Red Blood Cells Interplay Jointly Assessed by Optical Tweezers and Microscopy

  • Tatiana Avsievich,
  • Yana Tarakanchikova,
  • Ruixue Zhu,
  • Alexey Popov,
  • Alexander Bykov,
  • Ilya Skovorodkin,
  • Seppo Vainio and
  • Igor Meglinski

23 December 2019

In the framework of novel medical paradigm the red blood cells (RBCs) have a great potential to be used as drug delivery carriers. This approach requires an ultimate understanding of the peculiarities of mutual interaction of RBC influenced by nano-m...

  • Article
  • Open Access
4 Citations
3,333 Views
19 Pages

16 July 2022

The Order Coleoptera provides good examples of morphological specializations in the reproductive apparatus, gonadic maturation, and allometry differing between the sexes. The female and male reproductive apparatus has been modified to ensure reproduc...

  • Article
  • Open Access
1 Citations
1,227 Views
14 Pages

Introduction: The consumption of systemic antifungals is on the rise. However, a significant proportion of systemic antifungal prescriptions is inappropriate. Inappropriately prescribed antifungals are problematic, but there has been minimal emphasis...

  • Article
  • Open Access
3 Citations
1,890 Views
18 Pages

Assessing the In Vitro Potential of Glatiramer Acetate (Copaxone®) as a Chemotherapeutic Candidate for the Treatment of Cryptococcus neoformans Infection

  • Vinicius Alves,
  • Pedro Henrique Martins,
  • Bruna Miranda,
  • Iara Bastos de Andrade,
  • Luiza Pereira,
  • Christina Takiya Maeda,
  • Glauber Ribeiro de Sousa Araújo and
  • Susana Frases

25 July 2023

Cryptococcosis is a systemic mycosis affecting immunosuppressed individuals, caused by various Cryptococcus species. The current treatment utilizes a combination of antifungal drugs, but issues such as nephrotoxicity, restricted or limited availabili...

  • Article
  • Open Access
1 Citations
1,526 Views
28 Pages

Synthesis and Investigation of Physicochemical and Microbial Properties of Composites Containing Encapsulated Propolis and Sea Buckthorn Oil in Pectin Matrix

  • Liliana Woszczak,
  • Gohar Khachatryan,
  • Karen Khachatryan,
  • Mariusz Witczak,
  • Anna Lenart-Boroń,
  • Klaudia Stankiewicz,
  • Kinga Dworak,
  • Greta Adamczyk,
  • Agata Pawłowska and
  • Ireneusz Kapusta
  • + 3 authors

5 September 2025

This study explored the synthesis and characterization of pectin-based composites containing encapsulated propolis and sea buckthorn oil. Both propolis and sea buckthorn oil are well known for their antioxidant and antimicrobial properties. To mitiga...

  • Article
  • Open Access
5 Citations
4,783 Views
21 Pages

The Two-Component System 09 of Streptococcus pneumoniae Is Important for Metabolic Fitness and Resistance during Dissemination in the Host

  • Stephanie Hirschmann,
  • Alejandro Gómez-Mejia,
  • Thomas P. Kohler,
  • Franziska Voß,
  • Manfred Rohde,
  • Max Brendel and
  • Sven Hammerschmidt

The two-component regulatory system 09 of Streptococcus pneumoniae has been shown to modulate resistance against oxidative stress as well as capsule expression. These data and the implication of TCS09 in cell wall integrity have been shown for seroty...

  • Article
  • Open Access
10 Citations
5,354 Views
18 Pages

29 November 2020

Micron-sized core-shell particles consisting of a calcium carbonate (CaCO3) mineral shell and a fluidic core were generated using a biomimetic approach, for the purpose of use as biodegradable microcapsules for release of active agents. Dinoflagellat...

  • Article
  • Open Access
2 Citations
2,220 Views
17 Pages

30 September 2023

A drug-delivery system consisting of an inorganic host—layered double hydroxide (LDH)—and an anticancer drug—methotrexate (MTX)—was prepared via the intercalation route (MTX-LDH), and its hematocompatibility was investigated....

  • Feature Paper
  • Article
  • Open Access
4 Citations
3,914 Views
15 Pages

21 October 2024

In this work, multiwalled carbon nanotubes (MWCNTs) were melt-compounded into a novel thermal energy storage system consisting of a microencapsulated paraffin, with a melting temperature of 6 °C (M6D), dispersed within a flexible thermoplastic po...

  • Article
  • Open Access
20 Citations
7,501 Views
12 Pages

Ground Calcium Carbonate as a Low Cost and Biosafety Excipient for Solubility and Dissolution Improvement of Praziquantel

  • Ana Borrego-Sánchez,
  • Rita Sánchez-Espejo,
  • Beatrice Albertini,
  • Nadia Passerini,
  • Pilar Cerezo,
  • César Viseras and
  • C. Ignacio Sainz-Díaz

Calcium carbonate is an abundant mineral with several advantages to be a successful carrier to improve oral bioavailability of poorly water-soluble drugs, such as praziquantel. Praziquantel is an antiparasitic drug classified in group II of the Bioph...

  • Article
  • Open Access
4 Citations
7,206 Views
19 Pages

Histomorphology and Chemical Constituents of Interdigital Gland of Vembur Sheep, Ovis aries

  • Thangavel Rajagopal,
  • Selvam Mahalakshmi,
  • Thirukonda Ravindhran Gayathri,
  • Naganathan Muruganantham,
  • Marimuthu Muthukatturaja,
  • Durairaj Rajesh,
  • Kamatchi Rameshkumar,
  • Ponnirul Ponmanickam,
  • Mohammad Abdulkader Akbarsha and
  • Govindaraju Archunan

21 November 2022

The interdigital gland is a specialized skin gland located between the digits of Artiodactyla (i.e., even-toed ungulates). Its secretion participates in semiochemical communication, and protects from ultraviolet radiation as well as fungal and bacter...

  • Article
  • Open Access
7 Citations
3,300 Views
26 Pages

27 February 2024

Background: Theophylline (THN), a bronchodilator with potential applications in emerging conditions like COVID-19, requires a controlled-release delivery system due to its narrow therapeutic range and short half-life. This need is particularly crucia...

  • Article
  • Open Access
5 Citations
2,397 Views
12 Pages

15 January 2023

Many recent studies have revealed that PoL (Point of Load) converters’ output capacitors are a paramount component from a reliability point of view. To receive the maximum degree of reliability in many applications, designers are often advised...

  • Article
  • Open Access
8 Citations
4,189 Views
20 Pages

Morphometric, Histochemical, and Ultrastructural Analysis of the Reproductive System and Spermatogenic Stages of Male Blue Crab (Callinectessapidus Rathbun, 1896)

  • Awatef Ali,
  • Soheir El Sherif,
  • Jamila Abd Alla,
  • Sahya Maulu,
  • Ahmed A. Tantawy,
  • Mahmoud F. K. Soliman,
  • Mohamed M. Hassan,
  • Montaser M. Hassan and
  • Hala Saber Khalil

12 October 2021

The blue crab, Callinectes sapidus Rathbun, 1896, is considered to be a luxury meal, especially in touristic cities. It contains more than 20 types of amino acids and provides all the needed amounts for human growth. This study describes the morpholo...

  • Article
  • Open Access
6 Citations
3,575 Views
16 Pages

Enhanced Catalytic Dye Decolorization by Microencapsulation of Laccase from P. Sanguineus CS43 in Natural and Synthetic Polymers

  • Natalia Lopez-Barbosa,
  • Ana Lucía Campaña,
  • Juan C. Cruz,
  • Nancy Ornelas-Soto and
  • Johann F. Osma

16 June 2020

Polymeric microcapsules with the fungal laccase from Pycnoporus sanguineus CS43 may represent an attractive avenue for the removal or degradation of dyes from wastewaters. Microcapsules of alginate/chitosan (9.23 ± 0.12 µm) and poly(styr...

  • Article
  • Open Access
2 Citations
1,588 Views
22 Pages

In Situ Evaluation of Epoxy Self-Healing Coating by Encapsulated Linseed Oil in Poly(Urea–Formaldehyde–Melamine) Microcapsules

  • Lucas Henrique de Oliveira Souza,
  • Michele Fedel,
  • Fernando Cotting and
  • Wagner Reis da Costa Campos

23 April 2025

The development of self-healing coatings represents a promising approach to enhance the durability of metal substrates exposed to corrosive environments, demanding thorough in situ investigations. In this study, poly(urea–formaldehyde–mel...

  • Article
  • Open Access
11 Citations
6,652 Views
20 Pages

17 May 2018

Replacement of albite by sodium-rich, secondary phases is a common phenomenon, observed in different geological settings and commonly attributed to alkaline metasomatism. We investigated growth of nepheline and sodalite on albite in time series exper...

  • Article
  • Open Access
1,115 Views
27 Pages

27 September 2025

Objectives: The current work aimed to formulate and optimize a self-emulsifying microemulsion drug delivery system (SEME) for acemetacin (ACM) to increase ACM’s aqueous solubility, improve oral bioavailability, and reduce gastrointestinal compl...

  • Article
  • Open Access
18 Citations
8,414 Views
32 Pages

A Novel Melt-Dispersion Technique for Simplistic Preparation of Chlorpromazine-Loaded Polycaprolactone Nanocapsules

  • Thiresen Govender,
  • Yahya E. Choonara,
  • Pradeep Kumar,
  • Lisa C. Du Toit,
  • Girish Modi,
  • Dinesh Naidoo and
  • Viness Pillay

19 June 2015

The aim of this study was to design, synthesize and optimize chlorpromazine hydrochloride (CPZ)-loaded, poly-ε-caprolactone (PCL) based nanocapsules, intended for site specific delivery to the frontal lobe, using a novel melt-dispersion technique tha...

  • Article
  • Open Access
711 Views
18 Pages

The Development of Risperidone-Loaded Microfibers via Centrifugal Spinning to Enhance the Palatability of a Potential Drug for Autistic Children

  • Sarah H. Alqahtani,
  • Alhassan H. Aodah,
  • Yasser A. Alshawakir,
  • Bayan Y. Alshehri,
  • Ali A. Alamer,
  • Haya A. Alfassam,
  • Fahad A. Almughem,
  • Abdullah A. Alshehri and
  • Essam A. Tawfik

Background/Objectives: Children with autism spectrum disorder (ASD) frequently experience poor compliance with oral medication due to bitterness, unpleasant taste, and unsuitable dosage forms such as large tablets or capsules. Risperidone, a widely p...

  • Article
  • Open Access
21 Citations
3,077 Views
16 Pages

Introduction of Curdlan Optimizes the Comprehensive Properties of Methyl Cellulose Films

  • Liang Zhang,
  • Liang Xu,
  • Jin-Ke Ma,
  • Yun-Yue Ye,
  • Ying Chen and
  • Jian-Ya Qian

26 January 2023

The good oxygen barrier and hydrophobic properties of curdlan (CL) film might be suitable complements for MC film, and its similar glucose unit and thermal-gel character might endow the methyl cellulose (MC)/CL blended system with compatibility and g...