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  • Article
  • Open Access
15 Citations
4,969 Views
30 Pages

Solanum dulcamara L. Berries: A Convenient Model System to Study Redox Processes in Relation to Fruit Ripening

  • Milica Milutinović,
  • Đura Nakarada,
  • Jelena Božunović,
  • Miloš Todorović,
  • Uroš Gašić,
  • Suzana Živković,
  • Marijana Skorić,
  • Đurđa Ivković,
  • Jelena Savić and
  • Danijela Mišić
  • + 4 authors

1 February 2023

The present study provides, for the first time, a physicochemical and biochemical characterization of the redox processes associated with the ripening of Solanum dulcamara L. (bittersweet) berries. Electron Paramagnetic Resonance Spectroscopy (EPRS)...

(This article belongs to the Special Issue Antioxidant Capacity of Phenolic Compounds in Foods, Plants and Related By-Products)
  • Editorial
  • Open Access
1 Citations
2,001 Views
4 Pages

The Bittersweet Beat: Diabetes Complications

  • Joana Rossell,
  • Marina Idalia Rojo-López,
  • Josep Julve and
  • Didac Mauricio

13 June 2023

In this Editorial, we are focusing on a selection of articles recently published in the Journal of Clinical Medicine dealing with relevant aspects of cardiometabolic complications of diabetes mellitus [...]

(This article belongs to the Section Endocrinology & Metabolism)
  • Article
  • Open Access
11 Citations
2,964 Views
18 Pages

Metabolite Profiling and Identification of Sweet/Bitter Taste Compounds in the Growth of Cyclocarya Paliurus Leaves Using Multiplatform Metabolomics

  • Liang Chen,
  • Dai Lu,
  • Yuxi Wan,
  • Yaqian Zou,
  • Ruiyi Zhang,
  • Tao Zhou,
  • Bin Long,
  • Kangming Zhu,
  • Wei Wang and
  • Xing Tian

27 September 2024

Cyclocarya paliurus tea, also known as “sweet tea”, an herbal tea with Cyclocarya paliurus leaves as raw material, is famous for its unique nutritional benefits and flavor. However, due to the unique “bittersweet” of Cyclocary...

(This article belongs to the Special Issue Production, Quality, Flavor Characteristics and Health Benefits of Tea)
  • Review
  • Open Access
16 Citations
6,419 Views
22 Pages

A Bittersweet Computational Journey among Glycosaminoglycans

  • Giulia Paiardi,
  • Maria Milanesi,
  • Rebecca C. Wade,
  • Pasqualina D’Ursi and
  • Marco Rusnati

Glycosaminoglycans (GAGs) are linear polysaccharides. In proteoglycans (PGs), they are attached to a core protein. GAGs and PGs can be found as free molecules, associated with the extracellular matrix or expressed on the cell membrane. They play a ro...

(This article belongs to the Special Issue Structural and Functional Approach to the Glycan Diversity)
  • Communication
  • Open Access
28 Citations
6,620 Views
11 Pages

1 February 2018

An increasing body of literature demonstrates that consumers associate visual information with specific gustatory elements. This phenomenon is better known as cross-modal correspondence. A specific correspondence that has received attention of late i...

(This article belongs to the Special Issue Beverage Sensory Modification)
  • Review
  • Open Access
13 Citations
6,102 Views
18 Pages

Due to the global crisis caused by the dramatic rise of drug resistance among Gram-negative bacteria, there is an urgent need for a thorough understanding of the pathogenesis of infections of such an etiology. In light of the limited availability of...

(This article belongs to the Section Medical Microbiology)
  • Article
  • Open Access
5 Citations
3,160 Views
12 Pages

The Bittersweet Symphony of COVID-19: Associations between TAS1Rs and TAS2R38 Genetic Variations and COVID-19 Symptoms

  • Aurora Santin,
  • Beatrice Spedicati,
  • Alessandro Pecori,
  • Giuseppe Giovanni Nardone,
  • Maria Pina Concas,
  • Gioia Piatti,
  • Anna Menini,
  • Giancarlo Tirelli,
  • Paolo Boscolo-Rizzo and
  • Giorgia Girotto

3 February 2024

The innate immune system is crucial in fighting SARS-CoV-2 infection, which is responsible for coronavirus disease 2019 (COVID-19). Therefore, deepening our understanding of the underlying immune response mechanisms is fundamental for the development...

(This article belongs to the Section Physiology and Pathology)
  • Opinion
  • Open Access
2 Citations
2,576 Views
8 Pages

Bittersweet Sugars: How Unusual Glycan Structures May Connect Epithelial-to-Mesenchymal Transition and Multidrug Resistance in Cancer

  • Leonardo Marques da Fonseca,
  • Israel Diniz-Lima,
  • Marcos André Rodrigues da Costa Santos,
  • Tatiany Nunes Franklim,
  • Kelli Monteiro da Costa,
  • Ariely Costa dos Santos,
  • Alexandre Morrot,
  • Debora Decote-Ricardo,
  • Raphael do Carmo Valente and
  • Leonardo Freire-de-Lima
  • + 2 authors

Cancer cells are characterized by metabolic reprogramming, which enables their survival in of-ten inhospitable conditions. A very well-documented example that has gained attraction in re-cent years and is already considered a hallmark of transformed...

(This article belongs to the Section Cancer Biology and Anticancer Therapeutics)
  • Article
  • Open Access
36 Citations
6,192 Views
11 Pages

The Bittersweet Effects of COVID-19 on Mental Health: Results of an Online Survey among a Sample of the Dutch Population Five Weeks after Relaxation of Lockdown Restrictions

  • Mandy Gijzen,
  • Laura Shields-Zeeman,
  • Marloes Kleinjan,
  • Hans Kroon,
  • Henriëtte van der Roest,
  • Linda Bolier,
  • Filip Smit and
  • Derek de Beurs

Previous research shows that crises can have both negative and positive mental health effects on the population. The current study explored these effects in the context of the COVID-19 pandemic after relaxation of governmental measures. An online sur...

(This article belongs to the Special Issue Mental Health in the Time of COVID-19)
  • Article
  • Open Access
4 Citations
2,974 Views
17 Pages

Genetic Loci of Plant Pathogenic Dickeya solani IPO 2222 Expressed in Contact with Weed-Host Bittersweet Nightshade (Solanum dulcamara L.) Plants

  • Robert Czajkowski,
  • Dorota M. Krzyżanowska,
  • Daryna Sokolova,
  • Łukasz Rąbalski,
  • Maciej Kosiński,
  • Sylwia Jafra and
  • Aleksandra Królicka

28 February 2024

Dickeya solani, belonging to the Soft Rot Pectobacteriaceae, are aggressive necrotrophs, exhibiting both a wide geographic distribution and a wide host range that includes many angiosperm orders, both dicot and monocot plants, cultivated under all cl...

(This article belongs to the Section Molecular Plant Sciences)
  • Feature Paper
  • Review
  • Open Access
46 Citations
13,967 Views
14 Pages

20 February 2021

The fruit of the blackcurrant (Ribes nigrum L.) is round-shaped, dark purple, bittersweet, and seed-containing edible berries. The blackcurrant has been used as a traditional medicine in both Asia and European countries. It is known as a rich source...

(This article belongs to the Section Food Science and Technology)
  • Article
  • Open Access
12 Citations
5,882 Views
11 Pages

18 March 2016

A series of insecticidal dihydroagarofuran sesquiterpene polyesters were isolated from the root bark of Chinese bittersweet (Celastrus angulatus Max). A previous study indicated that these compounds affect the digestive system of insects, and aminope...

(This article belongs to the Section Plant Toxins)
  • Article
  • Open Access
27 Citations
6,065 Views
11 Pages

19 May 2015

Celangulin V, an insecticidal compound isolated from the root bark of Chinese bittersweet, can affect the digestive system of insects. However, the mechanism of how Celangulin V induces a series of symptoms is still unknown. In this study, affinity c...

  • Article
  • Open Access
17 Citations
14,128 Views
8 Pages

28 November 2013

The potential for dynamic chirality of an azapeptide nitrogen was examined by substitution of nitrogen for the α-carbon of the aspartate residue in the sweetener S,S-aspartame. Considering that S,S- and R,S-aspartame possess sweet and bitter tastes...

(This article belongs to the Special Issue Dynamic Stereochemistry)
  • Article
  • Open Access
9 Citations
5,234 Views
13 Pages

Effect of Three Post-Harvest Methods at Different Altitudes on the Organoleptic Quality of C. canephora Coffee

  • Sofía Velásquez,
  • Carlos Banchón,
  • Willian Chilán and
  • José Guerrero-Casado

13 December 2022

C. canephora (syn. C. robusta) is distinctive due to its rising industrial value and pathogen resistance. Both altitude and post-harvest methods influence coffee cup quality; however, modest information is known about this coffee species. Therefore,...

(This article belongs to the Section Tea, Coffee, Water, and Other Non-Alcoholic Beverages)
  • Article
  • Open Access
24 Citations
9,350 Views
12 Pages

“Maybe it’s Not Just the Food?” A Food and Mood Focus Group Study

  • Megan F. Lee,
  • Douglas Angus,
  • Hayley Walsh and
  • Sally Sargeant

Epidemiological and intervention studies in nutritional psychiatry suggest that the risk of mood disorders is associated with what we eat. However, few studies use a person-centred approach to explore the food and mood relationship. In this qualitati...

(This article belongs to the Special Issue Diet and Its Role in Preventing and Managing Health Disparities in People Living with Mental Illness)
  • Essay
  • Open Access
1 Citations
3,449 Views
15 Pages

This paper recounts the author’s reluctant journey of translating Matthew Fuller and Eyal Weizman’s Investigative Aesthetics: Conflicts and Commons in the Politics of Truth into Japanese, a process that turned out to be a mix of philosoph...

(This article belongs to the Special Issue The Aesthetics of the Performing Arts in the Contemporary Landscape)
  • Article
  • Open Access
2 Citations
3,899 Views
16 Pages

11 December 2023

The raspberry (Rubus idaeus L.) is a soft red fruit consumed worldwide due to its bitter-sweet taste and phenolics-associated health benefits. During plant dormancy, raspberry fruits are discarded. However, this work hypothesised that these fruits ha...

(This article belongs to the Special Issue Agro-Food Chain By-Products and Plant Origin Food to Obtain High-Value-Added Foods)
  • Article
  • Open Access
27 Citations
6,924 Views
14 Pages

Ethylene Differentially Modulates Hypoxia Responses and Tolerance across Solanum Species

  • Sjon Hartman,
  • Nienke van Dongen,
  • Dominique M.H.J. Renneberg,
  • Rob A.M. Welschen-Evertman,
  • Johanna Kociemba,
  • Rashmi Sasidharan and
  • Laurentius A.C.J. Voesenek

13 August 2020

The increasing occurrence of floods hinders agricultural crop production and threatens global food security. The majority of vegetable crops are highly sensitive to flooding and it is unclear how these plants use flooding signals to acclimate to impe...

(This article belongs to the Special Issue Plant Responses to Hypoxia)
  • Feature Paper
  • Article
  • Open Access
15 Citations
2,749 Views
13 Pages

Evaluation of the Photocatalytic Activity of Distinctive-Shaped ZnO Nanocrystals Synthesized Using Latex of Different Plants Native to the Amazon Rainforest

  • Robert S. Matos,
  • John M. Attah-Baah,
  • Michael D. S. Monteiro,
  • Benilde F. O. Costa,
  • Marcelo A. Mâcedo,
  • Simone P. A. Da Paz,
  • Rômulo S. Angélica,
  • Tiago M. de Souza,
  • Ştefan Ţălu and
  • Nilson S. Ferreira
  • + 1 author

22 August 2022

ZnO nanocrystals with three different morphologies have been synthesized via a simple sol-gel-based method using Brosimum parinarioides (bitter Amapá) and Parahancornia amapa (sweet Amapá) latex as chelating agents. X-ray diffraction (XRD) and electr...

(This article belongs to the Special Issue Nanomaterial Application in Environmental Monitoring and Water Treatment)
  • Article
  • Open Access
16 Citations
5,305 Views
12 Pages

11 October 2017

Celangulin V (CV), one of dihydroagarofuran sesquiterpene polyesters isolated from Chinese bittersweet (Celastrus angulatus Maxim), is famous natural botanical insecticide. Decades of research suggests that is displays excellent insecticidal activity...

(This article belongs to the Section Bioorganic Chemistry)
  • Article
  • Open Access
37 Citations
6,017 Views
10 Pages

13 April 2020

In this study, the feasibility of non-targeted UHPLC-HRMS fingerprints as chemical descriptors to address the classification and authentication of paprika samples was evaluated. Non-targeted UHPLC-HRMS fingerprints were obtained after a simple sample...

(This article belongs to the Special Issue Recent Developments in the Applications of Fingerprinting Technology in the Food Field)
  • Article
  • Open Access
6 Citations
4,691 Views
12 Pages

Identification of Human Brain Proteins for Bitter-Sweet Taste Perception: A Joint Proteome-Wide and Transcriptome-Wide Association Study

  • Wenming Wei,
  • Bolun Cheng,
  • Dan He,
  • Yijing Zhao,
  • Xiaoyue Qin,
  • Qingqing Cai,
  • Na Zhang,
  • Xiaoge Chu,
  • Sirong Shi and
  • Feng Zhang

23 May 2022

Objective: Bitter or sweet beverage perception is associated with alterations in brain structure and function. Our aim is to analyze the genetic association between bitter or sweet beverage perception and human brain proteins. Materials and methods:...

(This article belongs to the Special Issue Implications of Taste and Olfaction in Nutrition and Health)
  • Article
  • Open Access
22 Citations
5,431 Views
19 Pages

Flavor traits in citrus are the result of a blend of low molecular weight metabolites including sugars, acids, flavonoids and limonoids, these latter being mainly responsible for the characteristic bitter flavor in citrus. In this work, the genotype-...

(This article belongs to the Special Issue Plant Metabolism in Crops: A Systems Biology Perspective)
  • Review
  • Open Access
48 Citations
15,666 Views
24 Pages

In vivo X-Ray Computed Tomographic Imaging of Soft Tissue with Native, Intravenous, or Oral Contrast

  • Connor A. Wathen,
  • Nathan Foje,
  • Tony Van Avermaete,
  • Bernadette Miramontes,
  • Sarah E. Chapaman,
  • Todd A. Sasser,
  • Raghuraman Kannan,
  • Steven Gerstler and
  • W. Matthew Leevy

27 May 2013

X-ray Computed Tomography (CT) is one of the most commonly utilized anatomical imaging modalities for both research and clinical purposes. CT combines high-resolution, three-dimensional data with relatively fast acquisition to provide a solid platfo...

(This article belongs to the Special Issue Medical & Biological Imaging)
  • Review
  • Open Access
9 Citations
4,508 Views
24 Pages

Looking for Resistance to Soft Rot Disease of Potatoes Facing Environmental Hypoxia

  • Tomasz Maciag,
  • Edmund Kozieł,
  • Katarzyna Otulak-Kozieł,
  • Sylwia Jafra and
  • Robert Czajkowski

Plants are exposed to various stressors, including pathogens, requiring specific environmental conditions to provoke/induce plant disease. This phenomenon is called the “disease triangle” and is directly connected with a particular plant&...

(This article belongs to the Special Issue Advances in Plant–Pathogen Interactions: 3rd Edition)