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37 Results Found

  • Article
  • Open Access
765 Views
19 Pages

20 March 2026

A new universal construction of intermediate-layer-free solid-contact ion-selective electrodes using a novel inner electrode, namely microelectrodes array composed of a large number of individual microelectrodes, was developed. This approach eliminat...

  • Abstract
  • Open Access
1,189 Views
3 Pages

Influence of Ultrasonic Bath on Mold-Assisted Electrodeposition of Gold Microelectrode Arrays

  • Neeraj Yadav,
  • Flavio Giacomozzi,
  • Alessandro Cian,
  • Damiano Giubertoni and
  • Leandro Lorenzelli

This study investigates the potential of ultrasonic baths to enhance mold-assisted electrodeposition for fabricating three-dimensional (3D) microelectrode arrays (MEAs) with improved quality and reliability. Focusing on gold microstructures, commonly...

(This article belongs to the Proceedings of XXXV EUROSENSORS Conference)
  • Article
  • Open Access
651 Views
17 Pages

7 July 2026

The present study reports the application of a gold microelectrode array to determine copper(II) ions by anodic stripping voltammetry (ASV). The microelectrode characterization of the presented working electrode was investigated. Moreover, the way of...

(This article belongs to the Section Environmental Sensing)
  • Article
  • Open Access
8 Citations
2,595 Views
15 Pages

13 February 2024

This article presents a new working electrode based on a bismuth-plated, gold-based microelectrode array, which is suitable for determining thallium(I) species using anodic stripping voltammetry (ASV). It allowed a significant increase in the sensiti...

(This article belongs to the Section Sensors Development)
  • Article
  • Open Access
10 Citations
7,923 Views
13 Pages

Robust Functionalization of Large Microelectrode Arrays by Using Pulsed Potentiostatic Deposition

  • Joerg Rothe,
  • Olivier Frey,
  • Rajtarun Madangopal,
  • Jenna Rickus and
  • Andreas Hierlemann

23 December 2016

Surface modification of microelectrodes is a central step in the development of microsensors and microsensor arrays. Here, we present an electrodeposition scheme based on voltage pulses. Key features of this method are uniformity in the deposited ele...

(This article belongs to the Special Issue Integrated Sensor Arrays and Array Signal Processing)
  • Article
  • Open Access
15 Citations
6,524 Views
16 Pages

15 August 2019

Microelectrodes offer higher current density and lower ohmic drop due to increased radial diffusion. They are beneficial for electroanalytical applications, particularly for the detection of analytes at trace concentrations. Microelectrodes can be fa...

  • Article
  • Open Access
31 Citations
10,838 Views
13 Pages

Sensing Arrays Constructed from Nanoparticle Thin Films and Interdigitated Microelectrodes

  • Lingyan Wang,
  • Nancy N. Kariuki,
  • Mark Schadt,
  • Derrick Mott and ,
  • Jin Luo,
  • Chuan-Jian Zhong,
  • Xiajing Shi,
  • Chen Zhang,
  • Weibing Hao and
  • Jian-Q. Wang
  • + 7 authors+ 2 authors

22 June 2006

This paper describes the results of a study of a few design parameters influencingthe performance of sensor arrays constructed from nanostructured thin films andinterdigitated microelectrodes (IMEs). The nanostructured thin films on the IME deviceswe...

  • Article
  • Open Access
19 Citations
7,760 Views
11 Pages

An Electrochemical Microsensor Based on a AuNPs-Modified Microband Array Electrode for Phosphate Determination in Fresh Water Samples

  • Fangfang Wang,
  • Jianhua Tong,
  • Yang Li,
  • Chao Bian and ,
  • Jizhou Sun and
  • Shanhong Xia
  • + 1 author+ 0 author

19 December 2014

This work describes the fabrication, characterization, and application of a gold microband array electrode (MAE) for the determination of phosphate in fresh water samples. The working principle of this MAE is based on the reduction of a molybdophosph...

(This article belongs to the Section Chemical Sensors)
  • Proceeding Paper
  • Open Access
2 Citations
4,894 Views
8 Pages

A Novel Low-Cost Method for Fabrication of 2D Multi-Electrode Array (MEA) to Evaluate Functionality of Neuronal Cells

  • Tala Ahmadvand,
  • Sara Mirsadeghi,
  • Faezeh Shanehsazzadeh,
  • Sahar Kiani and
  • Mehdi Fardmanesh

2 November 2020

In this paper, a fabrication method for two-dimensional multi-electrode arrays (MEAs) using inexpensive material and method is proposed. The focus in this work is on the design and fabrication of 2D Microelectrode arrays using metallic electrodes on...

(This article belongs to the Proceedings of The 1st International Electronic Conference on Biosensors)
  • Article
  • Open Access
20 Citations
11,636 Views
11 Pages

Electrochemical Characterisation and Application of Multi Microelectrode Array Devices to Biological Electrochemistry

  • Michael Kudera,
  • H. Allen O. Hill,
  • Peter J. Dobson,
  • Peter A. Leigh and
  • William S. McIntire

20 June 2001

A new design for microelectrode array (MEA) devices fabricated by semiconductor-processing techniques is presented. The microelectrode surfaces consist of gold and are surrounded by an insulating silicon nitride layer. Each chip of these so-called Mu...

  • Feature Paper
  • Article
  • Open Access
4 Citations
3,714 Views
13 Pages

Electrodeformation of White Blood Cells Enriched with Gold Nanoparticles

  • Nicholas G. Hallfors,
  • Jeremy C. M. Teo,
  • Peter M. Bertone,
  • Chakra P. Joshi and ,
  • Ajymurat Orozaliev,
  • Matthew N. Martin and
  • A. F. Isakovic
  • + 2 authors+ 0 author

10 January 2022

The elasticity of white blood cells (WBCs) provides valuable insight into the condition of the cells themselves, the presence of some diseases, as well as immune system activity. In this work, we describe a novel process of refined control of WBCs&rs...

(This article belongs to the Section Biological Processes and Systems)
  • Article
  • Open Access
436 Views
17 Pages

Electrochemical Stability of Electrodeposited PEDOT:PSS Neural Stimulation Electrodes

  • Amirhossein Azami,
  • Yupeng Wu,
  • Christopher K. Nguyen,
  • Justin R. Abbott and ,
  • Mark E. Orazem,
  • Kevin J. Otto,
  • Stuart F. Cogan and
  • Brian N. Kim
  • + 3 authors+ 0 author

17 October 2026

Microelectrode arrays are used for neural stimulation and recording; however, their performance is limited by the high impedance and low charge-injection capacity of conventional metallic interfaces. To overcome these challenges, a variety of coating...

(This article belongs to the Special Issue Integrated Bioelectronic Interfaces for Neuroengineering)
  • Article
  • Open Access
15 Citations
5,995 Views
13 Pages

A Minimally Invasive Microsensor Specially Designed for Simultaneous Dissolved Oxygen and pH Biofilm Profiling

  • Xavier Guimerà,
  • Ana Moya,
  • Antonio David Dorado,
  • Xavi Illa and ,
  • Rosa Villa,
  • David Gabriel,
  • Xavier Gamisans and
  • Gemma Gabriel
  • + 3 authors+ 0 author

1 November 2019

A novel sensing device for simultaneous dissolved oxygen (DO) and pH monitoring specially designed for biofilm profiling is presented in this work. This device enabled the recording of instantaneous DO and pH dynamic profiles within biofilms, improvi...

(This article belongs to the Section Chemical Sensors)
  • Article
  • Open Access
8 Citations
2,747 Views
12 Pages

18 October 2022

A microfluidic impedance sensor embedded with gold interdigitated array microelectrodes was utilized to rapidly detect Tomato Ringspot Virus (ToRSV) and achieve efficient and precise detection. The electrochemical impedance spectrum was obtained by i...

(This article belongs to the Section B1: Biosensors)
  • Article
  • Open Access
965 Views
12 Pages

A Multichannel Solid-State Potentiometric Sensor Array for Heavy Metal Ions

  • Zongfeng Wei,
  • Guanliang Li,
  • Zhuqing Wang,
  • Shicai Xu and ,
  • Enguang Lv and
  • Weiwei Yue
  • + 1 author+ 0 author

10 May 2026

Heavy metal ions are common environmental contaminants that threaten aquatic ecosystems and human health. However, conventional analytical techniques often require expensive instrumentation and complex sample pretreatment. This work presents a peptid...

(This article belongs to the Special Issue Electrochemical Sensors and Biosensors: Materials, Methods and Applications)
  • Communication
  • Open Access
4 Citations
3,918 Views
11 Pages

Low-Cost Impedance Camera for Cell Distribution Monitoring

  • Bo Tang,
  • Mengxi Liu and
  • Andreas Dietzel

16 February 2023

Electrical impedance spectroscopy (EIS) is widely recognized as a powerful tool in biomedical research. For example, it allows detection and monitoring of diseases, measuring of cell density in bioreactors, and characterizing the permeability of tigh...

(This article belongs to the Section Biosensor and Bioelectronic Devices)
  • Article
  • Open Access
9 Citations
3,895 Views
14 Pages

Dopamine Measurement Using Engineered CNT–CQD–Polymer Coatings on Pt Microelectrodes

  • Mahdieh Darroudi,
  • Kevin A. White,
  • Matthew A. Crocker and
  • Brian N. Kim

15 March 2024

This study aims to develop a microelectrode array-based neural probe that can record dopamine activity with high stability and sensitivity. To mimic the high stability of the gold standard method (carbon fiber electrodes), the microfabricated platinu...

(This article belongs to the Section Biosensors)
  • Article
  • Open Access
37 Citations
11,623 Views
18 Pages

Application of an E-Tongue to the Analysis of Monovarietal and Blends of White Wines

  • Manuel Gutiérrez,
  • Andreu Llobera,
  • Andrey Ipatov,
  • Jordi Vila-Planas and ,
  • Santiago Mínguez,
  • Stefanie Demming,
  • Stephanus Büttgenbach,
  • Fina Capdevila,
  • Carme Domingo and
  • Cecilia Jiménez-Jorquera
  • + 5 authors+ 0 author

3 May 2011

This work presents a multiparametric system capable of characterizing and classifying white wines according to the grape variety and geographical origin. Besides, it quantifies specific parameters of interest for quality control in wine. The system,...

(This article belongs to the Special Issue Bioinspired Sensor Systems)
  • Article
  • Open Access
7 Citations
6,597 Views
19 Pages

Proof of Concept for Sustainable Manufacturing of Neural Electrode Array for In Vivo Recording

  • Szu-Ying Li,
  • Hsin-Yi Tseng,
  • Bo-Wei Chen,
  • Yu-Chun Lo and ,
  • Huai-Hsuan Shao,
  • Yen-Ting Wu,
  • Ssu-Ju Li,
  • Ching-Wen Chang,
  • Ta-Chung Liu and
  • You-Yin Chen
  • + 9 authors+ 4 authors

16 February 2023

Increasing requirements for neural implantation are helping to expand our understanding of nervous systems and generate new developmental approaches. It is thanks to advanced semiconductor technologies that we can achieve the high-density complementa...

(This article belongs to the Special Issue Multimodal, Multifunctional Biosensors or Imaging Systems and Their Biomedical Applications)
  • Article
  • Open Access
9 Citations
6,750 Views
15 Pages

A Multipurpose CMOS Platform for Nanosensing

  • Alberto Bonanno,
  • Alessandro Sanginario,
  • Simone L. Marasso,
  • Beatrice Miccoli and ,
  • Katarzyna Bejtka,
  • Simone Benetto and
  • Danilo Demarchi
  • + 2 authors+ 0 author

30 November 2016

This paper presents a customizable sensing system based on functionalized nanowires (NWs) assembled onto complementary metal oxide semiconductor (CMOS) technology. The Micro-for-Nano (M4N) chip integrates on top of the electronics an array of aluminu...

(This article belongs to the Special Issue System-Integrated Intelligence and Intelligent Systems)
  • Article
  • Open Access
2 Citations
1,471 Views
21 Pages

Enhanced Response of ZnO Nanorod-Based Flexible MEAs for Recording Ischemia-Induced Neural Activity in Acute Brain Slices

  • José Ignacio Del Río De Vicente,
  • Valeria Marchetti,
  • Ivano Lucarini,
  • Elena Palmieri and ,
  • Davide Polese,
  • Luca Montaina,
  • Francesco Maita,
  • Jan Kriska,
  • Jana Tureckova and
  • Luca Maiolo
  • + 6 authors+ 1 author

30 July 2025

Brain ischemia is a severe condition caused by reduced cerebral blood flow, leading to the disruption of ion gradients in brain tissue. This imbalance triggers spreading depolarizations, which are waves of neuronal and glial depolarization propagatin...

(This article belongs to the Section Biology and Medicines)
  • Article
  • Open Access
10 Citations
11,177 Views
20 Pages

Design, Fabrication and Characterization of a Low-Impedance 3D Electrode Array System for Neuro-Electrophysiology

  • Mihaela Kusko,
  • Florea Craciunoiu,
  • Bogdan Amuzescu,
  • Ferdinand Halitzchi and ,
  • Tudor Selescu,
  • Antonio Radoi,
  • Marian Popescu,
  • Monica Simion,
  • Adina Bragaru and
  • Teodora Ignat
  • + 5 authors+ 0 author

3 December 2012

Recent progress in patterned microelectrode manufacturing technology and microfluidics has opened the way to a large variety of cellular and molecular biosensor-based applications. In this extremely diverse and rapidly expanding landscape, silicon-ba...

(This article belongs to the Special Issue Live Cell-Based Sensors)
  • Article
  • Open Access
10 Citations
4,660 Views
20 Pages

Proliferation and Cluster Analysis of Neurons and Glial Cell Organization on Nanocolumnar TiN Substrates

  • Alice Abend,
  • Chelsie Steele,
  • Sabine Schmidt,
  • Ronny Frank and ,
  • Heinz-Georg Jahnke and
  • Mareike Zink
  • + 1 author+ 0 author

28 August 2020

Biomaterials employed for neural stimulation, as well as brain/machine interfaces, offer great perspectives to combat neurodegenerative diseases, while application of lab-on-a-chip devices such as multielectrode arrays is a promising alternative to a...

(This article belongs to the Special Issue Nano-Materials and Methods 2.0)
  • Article
  • Open Access
6 Citations
3,361 Views
19 Pages

15 February 2024

In the pursuit of refining the fabrication of three-dimensional (3D) microelectrode arrays (MEAs), this study investigates the application of ultrasonic vibrations in template-assisted electrodeposition. This was driven by the need to overcome limita...

(This article belongs to the Special Issue Eurosensors 2023 Selected Papers)
  • Article
  • Open Access
6 Citations
3,036 Views
11 Pages

Quantifying Deformation and Migration Properties of U87 Glioma Cells Using Dielectrophoretic Forces

  • Meltem Elitas,
  • Monsur Islam,
  • Jan G. Korvink,
  • Esra Sengul and ,
  • Pouya Sharbati,
  • Beyzanur Ozogul and
  • Sumeyra Vural Kaymaz
  • + 2 authors+ 0 author

31 October 2022

Glioblastoma multiforme is one of the most aggressive malignant primary brain tumors. To design effective treatment strategies, we need to better understand the behavior of glioma cells while maintaining their genetic and phenotypic stability. Here,...

(This article belongs to the Section Wearable Biosensors)
  • Article
  • Open Access
23 Citations
12,024 Views
16 Pages

Organoleptic Analysis of Drinking Water Using an Electronic Tongue Based on Electrochemical Microsensors

  • Manuel Gutiérrez-Capitán,
  • Marta Brull-Fontserè and
  • Cecilia Jiménez-Jorquera

23 March 2019

The standards that establish water’s quality criteria for human consumption include organoleptic analysis. These analyses are performed by taste panels that are not available to all water supply companies with the required frequency. In this wo...

(This article belongs to the Special Issue Multivariate Data Analysis for Sensors and Sensor Arrays)
  • Article
  • Open Access
26 Citations
7,809 Views
12 Pages

Portable Electronic Tongue Based on Microsensors for the Analysis of Cava Wines

  • Pablo Giménez-Gómez,
  • Roger Escudé-Pujol,
  • Fina Capdevila,
  • Anna Puig-Pujol and ,
  • Cecilia Jiménez-Jorquera and
  • Manuel Gutiérrez-Capitán
  • + 1 author+ 0 author

27 October 2016

Cava is a quality sparkling wine produced in Spain. As a product with a designation of origin, Cava wine has to meet certain quality requirements throughout its production process; therefore, the analysis of several parameters is of great interest. I...

(This article belongs to the Special Issue Olfactory and Gustatory Sensors)
  • Article
  • Open Access
60 Citations
9,646 Views
16 Pages

Development of Amperometric Biosensors Based on Nanostructured Tyrosinase-Conducting Polymer Composite Electrodes

  • Stelian Lupu,
  • Cecilia Lete,
  • Paul Cătălin Balaure,
  • Dan Ion Caval and ,
  • Constantin Mihailciuc,
  • Boris Lakard,
  • Jean-Yves Hihn and
  • Francisco Javier del Campo
  • + 3 authors+ 0 author

21 May 2013

Bio-composite coatings consisting of poly(3,4-ethylenedioxythiophene) (PEDOT) and tyrosinase (Ty) were successfully electrodeposited on conventional size gold (Au) disk electrodes and microelectrode arrays using sinusoidal voltages. Electrochemical p...

(This article belongs to the Special Issue Ultramicroelectrode Electrochemistry - Theory and Applications)
  • Article
  • Open Access
10 Citations
4,668 Views
12 Pages

Highly Localized Enrichment of Trypanosoma brucei Parasites Using Dielectrophoresis

  • Devin Keck,
  • Callie Stuart,
  • Josie Duncan,
  • Emily Gullette and
  • Rodrigo Martinez-Duarte

26 June 2020

Human African trypanosomiasis (HAT), also known as sleeping sickness, is a vector-borne neglected tropical disease endemic to rural sub-Saharan Africa. Current methods of early detection in the affected rural communities generally begin with general...

(This article belongs to the Special Issue Micromachines for Dielectrophoresis)
  • Article
  • Open Access
1,032 Views
24 Pages

27 August 2026

Electrochemical detection is widely acknowledged as a promising technique for quantifying neuroactive molecules, credited to its low cost, portable hardware, and distinctive ability to enable in vivo real-time dynamic monitoring. However, key hurdles...

(This article belongs to the Special Issue Functional Low-Dimensional Materials for Optical and Electrochemical Sensing)
  • Article
  • Open Access
8 Citations
3,379 Views
15 Pages

Artificial Intelligence Algorithms Enable Automated Characterization of the Positive and Negative Dielectrophoretic Ranges of Applied Frequency

  • Matthew Michaels,
  • Shih-Yuan Yu,
  • Tuo Zhou,
  • Fangzhou Du and ,
  • Mohammad Abdullah Al Faruque and
  • Lawrence Kulinsky
  • + 1 author+ 0 author

28 February 2022

The present work describes the phenomenological approach to automatically determine the frequency range for positive and negative dielectrophoresis (DEP)—an electrokinetic force that can be used for massively parallel micro- and nano-assembly....

(This article belongs to the Special Issue Micro and Nano Manufacturing (WCMNM 2021))
  • Article
  • Open Access
5 Citations
4,630 Views
15 Pages

Adhesion of Neurons and Glial Cells with Nanocolumnar TiN Films for Brain-Machine Interfaces

  • Alice Abend,
  • Chelsie Steele,
  • Heinz-Georg Jahnke and
  • Mareike Zink

10 August 2021

Coupling of cells to biomaterials is a prerequisite for most biomedical applications; e.g., neuroelectrodes can only stimulate brain tissue in vivo if the electric signal is transferred to neurons attached to the electrodes’ surface. Besides, cell su...

(This article belongs to the Special Issue Nano-Materials and Methods 3.0)
  • Article
  • Open Access
8 Citations
6,381 Views
11 Pages

A Novel 3D Helical Microelectrode Array for In Vitro Extracellular Action Potential Recording

  • Negar Geramifard,
  • Jennifer Lawson,
  • Stuart F. Cogan and
  • Bryan James Black

8 October 2022

Recent advances in cell and tissue engineering have enabled long-term three-dimensional (3D) in vitro cultures of human-derived neuronal tissues. Analogous two-dimensional (2D) tissue cultures have been used for decades in combination with substrate...

(This article belongs to the Section B: Biology and Biomedicine)
  • Article
  • Open Access
17 Citations
3,874 Views
14 Pages

A Molecularly Imprinted Polypyrrole/GO@Fe3O4 Nanocomposite Modified Impedimetric Sensor for the Routine Monitoring of Lysozyme

  • Pablo Montoro-Leal,
  • Isaac A. M. Frías,
  • Elisa Vereda Alonso,
  • Abdelhamid Errachid and
  • Nicole Jaffrezic-Renault

5 September 2022

Lysozyme (LYS) applications encompass anti-bacterial activity, analgesic, and anti-inflammatory effects. In this work, a porous framework that was based on the polymerization of pyrrole (PPy) in the presence of multi-functional graphene oxide/iron ox...

(This article belongs to the Section Biosensor Materials)
  • Article
  • Open Access
5 Citations
5,483 Views
13 Pages

PEDOT Coated Thick Film Electrodes for In Situ Detection of Cell Adhesion in Cell Cultures

  • Heike Bartsch,
  • Ralf Peipmann,
  • Maren Klett,
  • Dana Brauer and ,
  • Andreas Schober and
  • Jens Müller
  • + 1 author+ 0 author

2 November 2018

Low temperature cofired ceramics (LTCC) provide a technology for the 3-dimensional integration of sensor arrays into bioreactors covering dimensions of several hundred micrometers. Since optical control in such assemblies is not possible, the in situ...

  • Review
  • Open Access
15 Citations
5,800 Views
23 Pages

Review of Underwater In Situ Voltammetry Analyzers for Trace Metals

  • Jian Zhang,
  • Shijun Wu,
  • Ziying Wu,
  • Feng Zhang and ,
  • Bo Jin and
  • Canjun Yang
  • + 1 author+ 0 author

This review is a comprehensive overview of recent advancements in underwater in situ heavy metal voltammetric analyzers (UIHVAs). It explores various types of in situ voltammetric analyzers, including the voltammetric in situ profiling system, submer...

(This article belongs to the Special Issue Advances in Electrochemical Sensing and Analysis)
  • Article
  • Open Access
22 Citations
6,673 Views
15 Pages

28 August 2017

Salmonella Typhimurium is one of the most dangerous foodborne pathogens and poses a significant threat to human health. The objective of this study was to develop a portable impedance immunosensing system for rapid and sensitive detection of S. Typhi...

(This article belongs to the Special Issue Sensors for Toxic and Pathogen Detection)