Skip to Content

38 Results Found

  • Article
  • Open Access
9 Citations
4,106 Views
17 Pages

In Vitro and Predictive Computational Toxicology Methods for the Neurotoxic Pesticide Amitraz and Its Metabolites

  • Marialuce Giorgini,
  • Mercedes Taroncher,
  • María-José Ruiz,
  • Yelko Rodríguez-Carrasco and
  • Josefa Tolosa

1 February 2023

The Varroa destructor parasite is responsible for varroasis in honeybees worldwide, the most destructive disease among parasitic diseases. Thus, different insecticides/acaricides have been widely used within beehives to control these parasitic diseas...

  • Article
  • Open Access
8 Citations
3,739 Views
30 Pages

Amitraz Resistance in French Varroa Mite Populations—More Complex Than a Single-Nucleotide Polymorphism

  • Ulrike Marsky,
  • Bénédicte Rognon,
  • Alexandre Douablin,
  • Alain Viry,
  • Miguel Angel Rodríguez Ramos and
  • Abderrahim Hammaidi

27 May 2024

Resistance against amitraz in Varroa mite populations has become a subject of interest in recent years due to the increasing reports of the reduced field efficacy of amitraz treatments, especially from some beekeepers in France and the United States....

  • Review
  • Open Access
7 Citations
7,769 Views
24 Pages

20 February 2025

Resistance to amitraz in Varroa destructor mites poses a significant challenge to global beekeeping, leading to the declining efficacy of treatments and increased colony losses. This study aims to comprehensively map, characterize, and analyze the st...

  • Article
  • Open Access
6 Citations
3,609 Views
15 Pages

Amitraz and Its Metabolites: Oxidative Stress-Mediated Cytotoxicity in HepG2 Cells and Study of Their Stability and Characterization in Honey

  • Marialuce Giorgini,
  • Mercedes Taroncher,
  • Josefa Tolosa,
  • María-José Ruiz and
  • Yelko Rodríguez-Carrasco

The population decrease of bees that has been observed in recent years due to the Varroa destructor parasite may endanger the production of bee-products whose demand is on the rise. To minimize the negative effects caused by this parasite, the pestic...

  • Article
  • Open Access
27 Citations
7,546 Views
12 Pages

Influence of Amitraz and Oxalic Acid on the Cuticle Proteolytic System of Apis mellifera L. Workers

  • Aneta Strachecka,
  • Jerzy Paleolog,
  • Krzysztof Olszewski and
  • Grzegorz Borsuk

27 August 2012

This work verifies that amitraz and oxalic acid treatment affect honeybee cuticle proteolytic enzymes (CPE). Three bee groups were monitored: oxalic acid treatment, amitraz treatment, control. Electrophoresis of hydrophilic and hydrophobic CPE was pe...

  • Article
  • Open Access
3 Citations
3,886 Views
12 Pages

Molecular Characterization of Octopamine/Tyramine Receptor Gene of Amitraz-Resistant Rhipicephalus (Boophilus) decoloratus Ticks from Uganda

  • Patrick Vudriko,
  • Rika Umemiya-Shirafuji,
  • Dickson Stuart Tayebwa,
  • Joseph Byaruhanga,
  • Benedicto Byamukama,
  • Maria Tumwebaze,
  • Xuenan Xuan and
  • Hiroshi Suzuki

We previously reported the emergence of amitraz-resistant Rhipicephalus (Boophilus) decoloratus ticks in the western region of Uganda. This study characterized the octopamine/tyramine receptor gene (OCT/Tyr) of amitraz-resistant and -susceptible R. (...

  • Article
  • Open Access
5 Citations
2,762 Views
8 Pages

Determination of a Discriminant Dose to Identify Resistance to Amitraz in Rhipicephalus sanguineus s.l. (Acari: Ixodidae) from Mexico

  • Francisco Martínez-Ibañez,
  • Carlos Cruz-Vázquez,
  • Jorge Osorio-Miranda,
  • Irene Vitela-Mendoza,
  • Leticia Medina-Esparza,
  • Rodolfo Lagunes-Quintanilla and
  • Arturo Chávez-Rodríguez

24 July 2023

The brown dog tick, Rhipicephalus sanguineus s.l., is considered the most widely distributed three-host tick in the world and has medical and veterinary importance; the control of infestation is carried out with acaricides, towards which it can devel...

  • Article
  • Open Access
7 Citations
3,342 Views
16 Pages

Chemical acaricides are widely used to control ticks and tick-borne pathogens in cattle. However, prolonged and indiscriminate use of these chemicals inevitably leads to the selection of resistant ticks. In-vitro bioassays (adult and larval immersion...

  • Article
  • Open Access
4 Citations
3,978 Views
10 Pages

Disposition Kinetics of Amitraz in Lactating Does

  • Sathish Nanjundappa,
  • Suresh Narayanan Nair,
  • Darsana Udayan,
  • Sreelekha Kanapadinchareveetil,
  • Mathew Jacob,
  • Reghu Ravindran and
  • Sanis Juliet

6 August 2021

Amitraz, a member of the formamidine pesticide family, commonly used for ectoparasite control, is applied as a dip or low-pressure hand spray to cattle and swine, and the neck collar on dogs. Data on amitraz were generated mainly on laboratory animal...

  • Article
  • Open Access
3 Citations
4,196 Views
11 Pages

Influence of Amitraz-Based Product Characteristics on Varroa Mite Population Control

  • Gabrielle Almecija,
  • Benjamin Poirot,
  • Paulo Mielgo,
  • Max Watkins and
  • Christelle Suppo

The presence of the Varroa destructor mite requires the use of acaricide treatments for honeybee colonies. Amitraz is one of the most common acaricide-active ingredients used by beekeepers. Certain Varroa mite populations have developed resistance to...

  • Article
  • Open Access
56 Citations
5,696 Views
12 Pages

Large-Scale Monitoring of Resistance to Coumaphos, Amitraz, and Pyrethroids in Varroa destructor

  • Carmen Sara Hernández-Rodríguez,
  • Óscar Marín,
  • Fernando Calatayud,
  • María José Mahiques,
  • Ana Mompó,
  • Inmaculada Segura,
  • Enrique Simó and
  • Joel González-Cabrera

4 January 2021

Varroa destructor is an ectoparasitic mite causing devastating damages to honey bee colonies around the world. Its impact is considered a major factor contributing to the significant seasonal losses of colonies recorded every year. Beekeepers usually...

  • Article
  • Open Access
1 Citations
1,691 Views
16 Pages

Honey bees (Apis mellifera) are major pollinators, playing a critical role in global food production, biodiversity, and ecosystem stability. However, their populations are increasingly threatened by multiple interacting stressors, including pesticide...

  • Article
  • Open Access
2 Citations
2,580 Views
11 Pages

8 March 2023

The requirement for the protection of bee colonies against Varroa destructor invasions has been noted by many breeders and is included as an aspect of the development of beekeeping. This research aimed to check the effect of the development of a colo...

  • Article
  • Open Access
33 Citations
10,229 Views
12 Pages

11 January 2017

Since Varroa mites may cause devastating losses of honey bees through direct feeding, transmitting diseases, and increasing pathogen susceptibility, chemical and mechanical practices commonly are used to reduce mite infestation. While miticide applic...

  • Article
  • Open Access
10 Citations
2,782 Views
12 Pages

Susceptibility of Amblyomma sculptum, Vector of Rickettsia rickettsii, Ticks from a National Park and an Experimental Farm to Different Synthetic Acaricides

  • Ennya Rafaella Neves Cardoso,
  • Stephani Félix Carvalho,
  • Sarah Alves Dias,
  • Rayane Almeida Santos,
  • Mariana Avelar Tavares,
  • Lucianne Cardoso Neves,
  • Warley Vieira de Freitas Paula,
  • Gracielle Teles Pádua,
  • Nicolas Jalowitzki de Lima and
  • Felipe da Silva Krawczak
  • + 8 authors

31 October 2023

Amblyomma sculptum is a relevant tick species from a One Health perspective, playing an important role as a vector of Rickettsia rickettsii, the main agent of spotted fever rickettsiosis in Brazil. In this study, we evaluated the susceptibility of tw...

  • Article
  • Open Access
9 Citations
3,932 Views
16 Pages

9 February 2023

Invertebrates have a diverse immune system that responds differently to stressors such as pesticides and pathogens, which leads to different degrees of susceptibility. Honeybees are facing a phenomenon called colony collapse disorder which is attribu...

  • Article
  • Open Access
1,509 Views
10 Pages

Does Glycerin Used in Varroa Treatments Alter Propolis Quality?

  • Freideriki Papakosta,
  • Konstantia Graikou,
  • Leonidas Charistos,
  • Antigoni Cheilari,
  • Fani Hatjina and
  • Ioanna Chinou

22 August 2025

In the current study, the impact of different acaricide treatments against Varroa (such as amitraz strips, oxalic and formic acid strips impregnated with glycerin, or the sublimation or instillation of oxalic acid) on glycerol residue levels of propo...

  • Article
  • Open Access
5 Citations
2,553 Views
16 Pages

Transcriptome Profiling of Rhipicephalus annulatus Reveals Differential Gene Expression of Metabolic Detoxifying Enzymes in Response to Acaricide Treatment

  • Amritha Achuthkumar,
  • Shamjana Uchamballi,
  • Kumar Arvind,
  • Deepa Azhchath Vasu,
  • Sincy Varghese,
  • Reghu Ravindran and
  • Tony Grace

Ticks are hematophagous ectoparasites of economic consequence by virtue of being carriers of infectious diseases that affect livestock and other sectors of the agricultural industry. A widely prevalent tick species, Rhipicephalus (Boophilus) annulatu...

  • Article
  • Open Access
5 Citations
2,509 Views
25 Pages

Taktic, an Amitraz-based insecticide, is commonly used in sub-Saharan Africa to treat cattle for ticks. Due to misuse in rural dipping pools, some ticks are showing resistance to Taktic. This work presents a low-cost e-nose with commercial sensors to...

  • Article
  • Open Access
10 Citations
4,241 Views
8 Pages

First Description of Acaricide Resistance in Populations of Rhipicephalus microplus Tick from the Lower Amazon, Brazil

  • Ana Beatriz Barbosa de Sousa,
  • Daniela Bianchi,
  • Elisa Mota Santos,
  • Salatiel Ribeiro Dias,
  • Poliana Leão Peleja,
  • Raidel Reis Santos,
  • Nohora Mercado Caruso and
  • Antonio Humberto Hamad Minervino

26 October 2022

There is limited information on the resistance to acaricidal drugs of the cattle tick Rhipicephalus microplus in the Lower Amazon region. Thus, we aimed to determine the efficiency of three widely used acaricide products (Amitraz, Cypermethrin, and D...

  • Article
  • Open Access
1,032 Views
14 Pages

Formic Acid-Based Preparation in Varroa destructor Control and Its Effects on Hygienic Behavior of Apis mellifera

  • Marko Ristanić,
  • Uroš Glavinić,
  • Jevrosima Stevanović,
  • Tamara Cvetković,
  • Aleksa Mijatović,
  • Branislav Vejnović and
  • Zoran Stanimirović

6 December 2025

Varroa destructor remains a major threat to honey bee (Apis mellifera) health, requiring effective and sustainable control strategies. In this study, a formic acid-based product (Formic Pro™) was tested for its varroacidal efficacy and effects...

  • Article
  • Open Access
15 Citations
5,518 Views
13 Pages

8 January 2019

Widespread use of agrochemicals in the U.S. has led to nearly universal contamination of beeswax in honey bee hives. The most commonly found agrochemicals in wax include beekeeper-applied miticides containing tau-fluvalinate, coumaphos, or amitraz, a...

  • Article
  • Open Access
2 Citations
2,232 Views
15 Pages

Toxicity of Common Acaricides, Disinfectants, and Natural Compounds against Eggs of Rhipicephalus annulatus

  • Samar M. Ibrahium,
  • Abdel-Azeem S. Abdel-Baki,
  • Sahar M. Gadelhaq,
  • Shawky M. Aboelhadid,
  • Hesham A. Mahran,
  • Saleh Al-Quraishy,
  • Abdulrahman Reyad and
  • Asmaa A. Kamel

24 September 2024

Ticks pose a significant threat due to their ability to lay thousands of eggs, which can persist in the environment for extended periods. While the impact of various compounds on adult and larval ticks has been studied, research on their efficacy aga...

  • Article
  • Open Access
14 Citations
4,665 Views
18 Pages

Effects of Synthetic Acaricides and Nosema ceranae (Microsporidia: Nosematidae) on Molecules Associated with Chemical Communication and Recognition in Honey Bees

  • Martín Pablo Porrini,
  • Paula Melisa Garrido,
  • María Laura Umpiérrez,
  • Leonardo Pablo Porrini,
  • Antonella Cuniolo,
  • Belén Davyt,
  • Andrés González,
  • Martín Javier Eguaras and
  • Carmen Rossini

8 December 2020

Acaricides and the gut parasite Nosema ceranae are commonly present in most productive hives. Those stressors could be affecting key semiochemicals, which act as homeostasis regulators in Apis mellifera colonies, such as cuticular hydrocarbons (CHC)...

  • Article
  • Open Access
38 Citations
5,372 Views
11 Pages

In Vitro Evaluation of Acute Toxicity of Five Citrus spp. Essential Oils towards the Parasitic Mite Varroa destructor

  • Roberto Bava,
  • Fabio Castagna,
  • Cristian Piras,
  • Ernesto Palma,
  • Giuseppe Cringoli,
  • Vincenzo Musolino,
  • Carmine Lupia,
  • Maria Rosaria Perri,
  • Giancarlo Statti and
  • Vincenzo Musella
  • + 1 author

13 September 2021

Varroa destructor is the most important ectoparasitic mite of honey bees that has a negative impact on bee health and honey production. The control programs are mainly based on the use of synthetic acaricides that are often administered indiscriminat...

  • Article
  • Open Access
18 Citations
5,146 Views
14 Pages

Pharmacological Properties of the Type 1 Tyramine Receptor in the Diamondback Moth, Plutella xylostella

  • Haihao Ma,
  • Qingting Huang,
  • Xiaoyi Lai,
  • Jia Liu,
  • Hang Zhu,
  • Yong Zhou,
  • Xile Deng and
  • Xiaomao Zhou

Tyramine receptors (TARs) can be activated by tyramine (TA) or octopamine (OA) and have been shown to be related to physiological regulation (e.g., gustatory responsiveness, social organization, and learning behavior) in a range of insect species. A...

  • Article
  • Open Access
1 Citations
2,073 Views
14 Pages

24 June 2025

Varroa destructor, an ectoparasitic mite of honey bees, is a major contributor to global colony declines. To manage infestations, beekeepers frequently apply both synthetic and organic miticides—sometimes in combination. While much attention ha...

  • Article
  • Open Access
52 Citations
12,465 Views
16 Pages

The efficacies of various acaricides in order to control a parasitic mite, the Varroa mite, Varroa destructor, of honey bees, were measured in two different settings, namely, in laboratory caged honey bees and in queen-right honey bee colonies. The V...

  • Article
  • Open Access
38 Citations
5,870 Views
14 Pages

Pesticide Residues and Metabolites in Greek Honey and Pollen: Bees and Human Health Risk Assessment

  • Konstantinos M. Kasiotis,
  • Effrosyni Zafeiraki,
  • Electra Manea-Karga,
  • Pelagia Anastasiadou and
  • Kyriaki Machera

6 February 2023

Background: Bees encounter a plethora of environmental contaminants during nectar and pollen collection from plants. Consequently, after their entrance into the beehives, the transfer of numerous pollutants to apicultural products is inevitable. Meth...

  • Article
  • Open Access
6 Citations
2,934 Views
13 Pages

Pharmacological Properties and Function of the PxOctβ3 Octopamine Receptor in Plutella xylostella (L.)

  • Hang Zhu,
  • Zheming Liu,
  • Haihao Ma,
  • Wei Zheng,
  • Jia Liu,
  • Yong Zhou,
  • Yilong Man,
  • Xiaomao Zhou and
  • Aiping Zeng

16 August 2022

The diamondback moth (Plutella xylostella) is one of the most destructive lepidopteran pests of cruciferous vegetables, and insights into regulation of its physiological processes contribute towards the development of new pesticides against it. Thus,...

  • Article
  • Open Access
31 Citations
4,564 Views
15 Pages

Residues of Pesticides and Heavy Metals in Polish Varietal Honey

  • Monika Kędzierska-Matysek,
  • Anna Teter,
  • Piotr Skałecki,
  • Barbara Topyła,
  • Piotr Domaradzki,
  • Ewa Poleszak and
  • Mariusz Florek

6 August 2022

The levels of chemical pollutants were determined in 30 samples of varietal honey from southeastern Poland, including 223 pesticides (insecticides, herbicides, fungicides, acaricides, plant growth regulators, and veterinary drugs) and 5 heavy metals...

  • Article
  • Open Access
1,465 Views
13 Pages

22 May 2025

Beekeepers use a variety of methods to control Varroa destructor (varroa). Chemical control relies heavily on flumethrin, amitraz, coumaphos, and tau-fluvalinate products. However, increasing colony losses in recent years have been linked to the deve...

  • Article
  • Open Access
13 Citations
5,537 Views
20 Pages

The Associated Decision and Management Factors on Cattle Tick Level of Infestation in Two Tropical Areas of Ecuador

  • Valeria Paucar,
  • Ximena Pérez-Otáñez,
  • Richar Rodríguez-Hidalgo,
  • Cecilia Perez,
  • Darío Cepeda-Bastidas,
  • Jorge Grijalva,
  • Sandra Enríquez,
  • Susana Arciniegas-Ortega,
  • Sophie O. Vanwambeke and
  • Claude Saegerman
  • + 1 author

Decision-making on tick control practices is linked to the level of knowledge about livestock farming and to the social context in which individuals practice them. Tick infestation is one of the main problems in tropical livestock production. The obj...

  • Article
  • Open Access
1 Citations
2,186 Views
10 Pages

Safeguarding Bee Health: Insights from a Collaborative Monitoring and Prevention Project Against Pesticide Poisonings

  • Mara Gasparini,
  • Giovanni Prestini,
  • Franco Rainini,
  • Gabriella Cancemi,
  • Silvia De Palo,
  • Livio Colombari and
  • Michele Mortarino

6 February 2025

In recent decades, bee poisoning due to pesticides and agrochemicals has increased, posing significant challenges to honey bee health and contributing to the so-called “Colony Collapse Disorder” (CCD). Poor knowledge about the level of ex...

  • Article
  • Open Access
3 Citations
2,721 Views
14 Pages

Phenotypic and Target-Directed Screening Yields New Acaricidal Alternatives for the Control of Ticks

  • Tatiana Saporiti,
  • Mauricio Cabrera,
  • Josefina Bentancur,
  • María Elisa Ferrari,
  • Nallely Cabrera,
  • Ruy Pérez-Montfort,
  • Francisco J. Aguirre-Crespo,
  • Jorge Gil,
  • Ulises Cuore and
  • Guzmán Alvarez
  • + 2 authors

13 December 2022

Rhipicephalus microplus, the “common cattle tick”, is the most important ectoparasite in livestock worldwide due to the economic and health losses it produces. This tick is a vector for pathogens of several tick-borne diseases. In Latin A...

  • Article
  • Open Access
7 Citations
3,301 Views
16 Pages

Chemical Profile of Essential Oils of Selected Lamiaceae Plants and In Vitro Activity for Varroosis Control in Honeybees (Apis mellifera)

  • Roberto Bava,
  • Fabio Castagna,
  • Carmine Lupia,
  • Stefano Ruga,
  • Vincenzo Musella,
  • Filomena Conforti,
  • Mariangela Marrelli,
  • Maria Pia Argentieri,
  • Domenico Britti and
  • Ernesto Palma
  • + 1 author

13 December 2023

The most significant ectoparasitic mite of honeybees, Varroa destructor, has a detrimental effect on bee health and honey output. The principal strategy used by the control programs is the application of synthetic acaricides. All of this has resulted...

  • Article
  • Open Access
22 Citations
6,364 Views
15 Pages

Green Veterinary Pharmacology for Honey Bee Welfare and Health: Origanum heracleoticum L. (Lamiaceae) Essential Oil for the Control of the Apis mellifera Varroatosis

  • Fabio Castagna,
  • Roberto Bava,
  • Cristian Piras,
  • Cristina Carresi,
  • Vincenzo Musolino,
  • Carmine Lupia,
  • Mariangela Marrelli,
  • Filomena Conforti,
  • Ernesto Palma and
  • Vincenzo Musella
  • + 1 author

9 March 2022

Varroatosis, caused by the Varroa destructor mite, is currently the most dangerous parasitic disease threatening the survival of honey bees worldwide. Its adverse effect on the welfare and health of honey bees requires the regular use of specific aca...

  • Review
  • Open Access
756 Views
20 Pages

Plants Used for Tick and Tick-Borne Disease Control in South Africa: Ethnoveterinary Knowledge, Bioactivity Evidence, and Translation Pathways

  • Tsireledzo Goodwill Makwarela,
  • Nimmi Seoraj-Pillai,
  • Dikeledi Petunia Malatji and
  • Tshifhiwa Constance Nangammbi

5 December 2025

Ticks and tick-borne diseases (TBDs) impose a heavy burden on South African livestock systems, particularly in resource-limited communal areas. Conventional acaricides are effective but face rising challenges of resistance, high costs, and concerns f...