You are currently on the new version of our website. Access the old version .

44 Results Found

  • Article
  • Open Access
7 Citations
4,414 Views
15 Pages

Multiple Genetic Loci Associated with Pug Dog Thoracolumbar Myelopathy

  • Gustaf Brander,
  • Cecilia Rohdin,
  • Matteo Bianchi,
  • Kerstin Bergvall,
  • Göran Andersson,
  • Ingrid Ljungvall,
  • Karin Hultin Jäderlund,
  • Jens Häggström,
  • Åke Hedhammar and
  • Kerstin Lindblad-Toh
  • + 1 author

1 February 2023

Pug dogs with thoracolumbar myelopathy (PDM) present with a specific clinical phenotype that includes progressive pelvic limb ataxia and paresis, commonly accompanied by incontinence. Vertebral column malformations and lesions, excessive scar tissue...

  • Article
  • Open Access
137 Views
17 Pages

Prospective Comparative Study of Topical Tacrolimus and Sirolimus for the Treatment of Pigmentary Keratitis in Pug Dogs

  • Diana Sarmiento Quintana,
  • Inmaculada Morales Fariña,
  • Jéssica González Pérez,
  • Manuel Morales Doreste,
  • José Raduan Jaber and
  • Juan Alberto Corbera

5 January 2026

Pigmentary keratitis (PK) is a prevalent ocular surface disease in Pug dogs, yet comparative evidence on topical immunosuppressants remains limited. This prospective comparative clinical study evaluated the efficacy and safety of two agents with dist...

  • Case Report
  • Open Access
2 Citations
8,906 Views
6 Pages

Dysuria Associated with Non-Neoplastic Bone Hyperplasia of the Os Penis in a Pug Dog

  • Noritaka Maeta,
  • Takako Shimokawa Miyama,
  • Kenji Kutara,
  • Teppei Kanda,
  • Ikki Mitsui,
  • Akihiro Ohnishi,
  • Masahiro Miyabe,
  • Yuki Shimizu,
  • Kaori Saeki and
  • Yasuhiko Okamura
  • + 1 author

2 January 2021

A three-year-old male Pug presented with a three-year history of urolithiasis and repeated urethral obstruction. Biochemical analysis, ultrasonography, and retrograde urethrocystography revealed probable portosystemic shunt and incomplete urethral ob...

  • Article
  • Open Access
2 Citations
3,104 Views
16 Pages

Ocular Surface Characteristics in Pugs with Pigmentary Keratitis in the Canary Islands, Spain

  • Diana Sarmiento Quintana,
  • Inmaculada Morales Fariña,
  • Jéssica González Pérez,
  • José Raduan Jaber and
  • Juan Alberto Corbera

9 February 2024

This study investigated the prevalence of pigmentary keratitis (PK) in Pug-breed dogs and described the ocular surface characteristics associated with this disease. A total of 219 eyes from 110 dogs were examined, with 94.5% of them affected by PK. A...

  • Article
  • Open Access
17 Citations
5,662 Views
13 Pages

2 March 2021

Relative macroglossia has been identified in brachycephalic compared to mesaticephalic dogs. This study assessed the tongue volume comparing three common brachycephalic breeds, including 30 French bulldogs, 30 pugs, and 15 English bulldogs. Computed...

  • Article
  • Open Access
13 Citations
3,948 Views
18 Pages

25 August 2023

In rapidly expanding Indian cities, the current provisions for public urban green spaces (PUGS) falls below the minimum standards recommended by the WHO, linked with the well-being of urban dwellers. The local authorities are struggling to fulfill th...

  • Communication
  • Open Access
13 Citations
4,519 Views
11 Pages

Pug-Headedness Anomaly in a Wild and Isolated Population of Native Mediterranean Trout Salmo trutta L., 1758 Complex (Osteichthyes: Salmonidae)

  • Francesco Palmas,
  • Tommaso Righi,
  • Alessio Musu,
  • Cheoma Frongia,
  • Cinzia Podda,
  • Melissa Serra,
  • Andrea Splendiani,
  • Vincenzo Caputo Barucchi and
  • Andrea Sabatini

15 September 2020

Skeletal anomalies are commonplace among farmed fish. The pug-headedness anomaly is an osteological condition that results in the deformation of the maxilla, pre-maxilla, and infraorbital bones. Here, we report the first record of pug-headedness in a...

  • Article
  • Open Access
3,143 Views
17 Pages

21 February 2025

Pugs are a popular brachycephalic breed that suffer from multiple chronic disorders linked to their exaggerated phenotypic traits. The contribution of these disorders to early death and euthanasia have not been described and would add urgency to addr...

  • Feature Paper
  • Article
  • Open Access
2 Citations
2,408 Views
49 Pages

23 July 2025

This paper investigates the cultural landscapes established by nineteenth-century German immigrants in South Australia and the southern Riverina of New South Wales, with particular attention to settlement patterns, architectural traditions and topony...

  • Feature Paper
  • Article
  • Open Access
1 Citations
1,528 Views
18 Pages

13 February 2025

Pugs are highly predisposed to corneal disorders, such as brachycephalic ocular syndrome (BOS), due to their disproportionate skull, reduced corneal sensitivity and eyelid anomalies such as distichiasis, entropion and lagophthalmos. The risk of corne...

  • Brief Report
  • Open Access
11 Citations
2,832 Views
9 Pages

26 October 2022

Numerous large dark plaques developed over the ventrum, legs and head of a 9-year-old pug dog over a 4-year-period. Histology confirmed a diagnosis of viral pigmented plaque and a short section of a novel papillomavirus (PV) type was amplified using...

  • Article
  • Open Access
7 Citations
5,553 Views
20 Pages

19 June 2023

Brachycephalic breeds have increased in popularity despite growing awareness of their predisposition to a wide range of conformation-related diseases. The extreme facial conformation of many popular brachycephalic breeds compromises their ocular surf...

  • Brief Report
  • Open Access
5 Citations
7,637 Views
10 Pages

1 October 2024

Background: Chiari-like malformation (CM), Syringomyelia (SM) and middle ear effusion (MEE) are frequently observed disorders in Cavalier King Charles Spaniels (CKCSs), Pomeranians, and less frequently the Griffon. There are a few reports in which sm...

  • Article
  • Open Access
13 Citations
6,201 Views
18 Pages

19 June 2022

Despite efforts of veterinarians and breeders, brachycephalic obstructive airway syndrome (BOAS) is still a common problem in pugs, underlining the need for objective tests to identify and prevent breeding with affected dogs. In the current study, a...

  • Article
  • Open Access
12 Citations
2,059 Views
17 Pages

Flexural Response of Concrete Specimen Retrofitted with PU Grout Material: Experimental and Numerical Modeling

  • Sadi Ibrahim Haruna,
  • Yasser E. Ibrahim,
  • Zhu Han and
  • Abdulwarith Ibrahim Bibi Farouk

17 October 2023

Polyurethane (PU) composite is increasingly used as a repair material for civil engineering infrastructure, including runway, road pavement, and buildings. Evaluation of polyurethane grouting (PUG) material is critical to achieve a desirable maintena...

  • Article
  • Open Access
13 Citations
3,160 Views
14 Pages

Prunetinoside Inhibits Lipopolysaccharide-Provoked Inflammatory Response via Suppressing NF-κB and Activating the JNK-Mediated Signaling Pathway in RAW264.7 Macrophage Cells

  • Abuyaseer Abusaliya,
  • Pritam Bhagwan Bhosale,
  • Hun Hwan Kim,
  • Sang Eun Ha,
  • Min Yeong Park,
  • Se Hyo Jeong,
  • Preethi Vetrivel,
  • Joon-Suk Park and
  • Gon Sup Kim

Inflammation is a multifaceted response of the immune system at the site of injury or infection caused by pathogens or stress via immune cells. Due to the adverse effects of chemical drugs, plant-based compounds are gaining interest in current resear...

  • Review
  • Open Access
46 Citations
7,467 Views
20 Pages

Punicalagin in Cancer Prevention—Via Signaling Pathways Targeting

  • Izabela Berdowska,
  • Małgorzata Matusiewicz and
  • Izabela Fecka

9 August 2021

The extract of pomegranate (Punica granatum) has been applied in medicine since ancient times due to its broad-spectrum health-beneficial properties. It is a rich source of hydrolyzable tannins and anthocyanins, exhibiting strong antioxidative, anti-...

  • Article
  • Open Access
14 Citations
7,183 Views
11 Pages

The fast and steady economic growth and social changes in recent years in Cambodia have brought rapid expansion and restructuring to its cities. These phenomena have brought numerous challenges including threats to urban green spaces (UGS’s). This st...

  • Article
  • Open Access
64 Citations
6,444 Views
11 Pages

2 January 2020

Digital light processing (DLP)-type 3D printing ensures several advantages, such as an easy solution process, a short printing time, high-quality printing, and selective light curing. Furthermore, polyurethane (PU) is among the promising candidates f...

  • Article
  • Open Access
3 Citations
4,505 Views
9 Pages

Assessment of Nasal Structure Using CT Imaging of Brachycephalic Dog Breeds

  • Ryo Oshita,
  • Sakie Katayose,
  • Eiichi Kanai and
  • Satoshi Takagi

25 June 2022

The response to treatment of brachycephalic airway syndrome (BAS) varies among brachycephalic dog breeds. We hypothesized that variations in nasal structure are one of the factors responsible for this difference. To confirm this variation, we measure...

  • Article
  • Open Access
5 Citations
3,521 Views
24 Pages

A Comparative Phylogeography of Three Marine Species with Different PLD Modes Reveals Two Genetic Breaks across the Southern Caribbean Sea

  • Juan Carlos Narváez-Barandica,
  • Julián F. Quintero-Galvis,
  • Juan Carlos Aguirre-Pabón,
  • Lyda R. Castro,
  • Ricardo Betancur and
  • Arturo Acero Pizarro

5 August 2023

The comparative phylogeography of marine species with contrasting dispersal potential across the southern Caribbean Sea was evaluated by the presence of two putative barriers: the Magdalena River plume (MRP) and the combination of the absence of a ro...

  • Article
  • Open Access
2 Citations
2,531 Views
16 Pages

Evaluation of the Submaximal Treadmill-Based Fitness Test in Six Brachycephalic Breeds—A Follow-Up Study

  • Jana D. Türkcü,
  • Sebastian Meller,
  • Pia S. Wiegel,
  • Ingo Nolte and
  • Holger A. Volk

3 November 2023

Brachycephalic obstructive airway syndrome (BOAS) in dogs challenges veterinary surgeons both with a complex clinical picture as well as wide-ranging ways to diagnose the disease, often not easily implemented nor standardised in clinical practice. Th...

  • Feature Paper
  • Article
  • Open Access
1 Citations
1,148 Views
22 Pages

5 September 2025

Lawns have evolved from medieval European grasslands into globally accepted urban green surfaces, serving recreational, aesthetic and cultural purposes. Today lawn surfaces are essential components of public urban green space (PUGS), fulfilling ecosy...

  • Article
  • Open Access
10 Citations
5,355 Views
18 Pages

Microclimate Classification of Bologna (Italy) as a Support Tool for Urban Services and Regeneration

  • Marianna Nardino,
  • Letizia Cremonini,
  • Teodoro Georgiadis,
  • Emanuele Mandanici and
  • Gabriele Bitelli

A microclimate classification of the entire Bologna Municipality has been carried out in order to give a tool to the local administration in the drafting of the General Urbanistic Plan (PUG). The city was classified considering the variation of air t...

  • Review
  • Open Access
13 Citations
18,368 Views
25 Pages

Dermatological Problems of Brachycephalic Dogs

  • Stefan Hobi,
  • Vanessa R. Barrs and
  • Paweł M. Bęczkowski

16 June 2023

Brachycephalic dogs are not only affected by brachycephalic obstructive airway syndrome (BOAS), but are also frequently referred to veterinary dermatologists for skin conditions, with English bulldogs and pugs particularly over-represented. Some skin...

  • Article
  • Open Access
2,417 Views
25 Pages

4 October 2023

Since the entry of Emilia-Romagna Regional Law No. 24/2017 Disciplina regionale sulla tutela e l’uso del territorio, the processes guiding the development of the territory have profoundly changed, in principle, in the structuring through proces...

  • Article
  • Open Access
7 Citations
4,858 Views
14 Pages

Proposal of an Initial Environmental Management and Land Use for Critical Cemeteries in Central Ecuador

  • Geomara Flores Gómez,
  • Tania Crisanto-Perrazo,
  • Theofilos Toulkeridis,
  • Greta Fierro-Naranjo,
  • Paulina Guevara-García,
  • Eduardo Mayorga-Llerena,
  • Diego Vizuete-Freire,
  • Esthela Salazar and
  • Izar Sinde-Gonzalez

29 January 2022

Cemeteries are sites for the final disposal of human bodies that constitute a source of contamination of soil and water as a result of the cadaveric decomposition generated. The current research performed an initial study on the contamination of soil...

  • Article
  • Open Access
1,438 Views
14 Pages

Immobilization and Kinetic Properties of ß-N-Acetylhexosaminidase from Penicillium oxalicum

  • Vladimír Štefuca,
  • Mária Bláhová,
  • Helena Hronská and
  • Michal Rosenberg

16 October 2024

The application of immobilized enzymes often plays a key role in successfully implementing an economically feasible biocatalytic process at an industrial scale. Designing an immobilized biocatalyst involves solving several tasks, from the selection o...

  • Case Report
  • Open Access
2,642 Views
14 Pages

Clinical Approach to Cleft Lip and Palate with or Without Surgical Correction in Ten Brachycephalic Puppies

  • Gleice Mendes Xavier,
  • Keylla Helena Nobre Pacífico Pereira,
  • Kárita da Mata Fuchs,
  • Júlia Cosenza Mendonça,
  • Rebeca Bastos Abibe,
  • Claudia Valéria Seullner Brandão,
  • Maricy Apparício,
  • Fabiana Ferreira de Souza,
  • Matheus Gabriel Crema and
  • Vânia Maria de Vasconcelos Machado
  • + 1 author

Congenital defects are among the leading causes of neonatal mortality in small animals. Among them, cleft palate is one of the most commonly found malformations in dogs. Appropriate clinical management and surgical correction are determining factors...

  • Article
  • Open Access
2 Citations
4,070 Views
16 Pages

Personalized Strategy for Animal-Assisted Therapy for Individuals Based on the Emotions Induced by the Images of Different Animal Species and Breeds

  • Jovita Luksaite,
  • Egle Zokaityte,
  • Vytaute Starkute,
  • Sonata Sidlauskiene,
  • Gintare Zokaityte and
  • Elena Bartkiene

27 February 2022

The aim of this study was to apply the FaceReader technique to select the animal species and breed for a personalized AAT based on the emotions (‘neutral’, ‘happy’, ‘sad’, ‘angry’, ‘surprised&rsqu...

  • Article
  • Open Access
38 Citations
3,750 Views
16 Pages

Astragalus Polysaccharide Promotes Doxorubicin-Induced Apoptosis by Reducing O-GlcNAcylation in Hepatocellular Carcinoma

  • Mingzhe Li,
  • Fangfang Duan,
  • Zhiqiang Pan,
  • Xiaomei Liu,
  • Wenli Lu,
  • Chao Liang,
  • Zhaoqin Fang,
  • Peike Peng and
  • Dongwei Jia

10 March 2023

The toxicity and side effects of chemotherapeutic drugs remain a crucial obstacle to the clinical treatment of hepatocellular carcinoma (HCC). Identifying combination therapy from Chinese herbs to enhance the sensitivity of tumors to chemotherapeutic...

  • Feature Paper
  • Article
  • Open Access
1 Citations
1,179 Views
31 Pages

29 August 2025

This study addresses the challenge of reliably identifying Public Urban Green Spaces (PUGS) in metropolitan areas, a key requirement for advancing equitable access to green infrastructure and monitoring progress toward SDG 11.7 and WHO recommendation...

  • Feature Paper
  • Article
  • Open Access
36 Citations
5,013 Views
27 Pages

Efficient Recovery of Rare Earth Elements (Pr(III) and Tm(III)) From Mining Residues Using a New Phosphorylated Hydrogel (Algal Biomass/PEI)

  • Chunlin He,
  • Khalid A.M. Salih,
  • Yuezhou Wei,
  • Hamed Mira,
  • Adel A.-H. Abdel-Rahman,
  • Khalid Z. Elwakeel,
  • Mohammed F. Hamza and
  • Eric Guibal

8 February 2021

With the target of recovering rare earth elements (REEs) from acidic leachates, a new functionalized hydrogel was designed, based on the phosphorylation of algal/polyethyleneimine beads. The functionalization strongly increased the sorption efficienc...

  • Article
  • Open Access
5 Citations
2,124 Views
19 Pages

The inherent brittle behavior of cementitious composite is considered one of its weaknesses in structural applications. This study evaluated the impact strength and failure modes of composite U-shaped normal concrete (NC) specimens strengthened with...

  • Article
  • Open Access
6 Citations
3,514 Views
11 Pages

Tools for Urban Climate Adaptation Plans: A Case Study on Bologna and Outcomes for Heat Wave Impact Reduction

  • Letizia Cremonini,
  • Teodoro Georgiadis,
  • Marianna Nardino,
  • Federica Rossi,
  • Alessandro Rossi,
  • Giovanna Pinca and
  • Massimiliano Fazzini

29 November 2023

The purpose of this paper is to describe the process of building a coherent frame for the identification of local environmental urban vulnerabilities, coping with heat waves’ increasing threats, and adopting specific adaptation policies in the...

  • Feature Paper
  • Article
  • Open Access
590 Views
23 Pages

Every Tumour Counts: A Comprehensive Overview of Canine Oncology in Portugal

  • Paula Brilhante-Simões,
  • Ricardo Lopes,
  • Leonor Delgado,
  • Augusto Silva,
  • Isabel Pires,
  • Ricardo Marcos,
  • Felisbina Queiroga and
  • Justina Prada

23 December 2025

Robust nationwide data on canine oncology in Portugal are scarce. We retrospectively reviewed 17,773 biopsy submissions received by a nationwide veterinary laboratory (2020–2024). After applying inclusion criteria, 6359 histopathology-confirmed...

  • Article
  • Open Access
1,670 Views
15 Pages

5 August 2025

The recent surge in the popularity of brachycephalic dog breeds has raised concerns about their predisposition to serious health issues linked to breed-specific morphological traits. This study examined the demographic characteristics, motivations, a...

  • Feature Paper
  • Article
  • Open Access
1,833 Views
15 Pages

24 March 2025

This study, which involved 868 patients, focused on size-dependent features (body size, pinna formation, brachycephaly, overweight) and their associations with the occurrence of canine Otitis externa. Breed, sex, and neuter status were also included....

  • Article
  • Open Access
8 Citations
3,047 Views
20 Pages

The Behaviour of Sheep around a Natural Waterway and Impact on Water Quality during Winter in New Zealand

  • Aloyce Bunyaga,
  • Rene Corner-Thomas,
  • Ina Draganova,
  • Paul Kenyon and
  • Lucy Burkitt

25 April 2023

Access of livestock, such as cattle, to waterways has been shown to be a cause of poor water quality due to pugging damage and excretion entering the water. In New Zealand, regulations require that cattle, deer, and pigs are excluded from accessing w...

  • Article
  • Open Access
1,536 Views
24 Pages

Evaluating the Greenness of Sanandaj City Using Sentinel Imagery in Google Earth Engine

  • Werya Lotfi,
  • Neda Abbasi,
  • Ali Cheshmehzangi,
  • Loghman Khodakarami and
  • Hamideh Nouri

13 April 2025

Urban greenery and cooling initiatives have become top priorities for municipalities worldwide as they contribute to improved environmental quality and urban resilience. This study leverages advancements in remote sensing (RS) and cloud-based process...

  • Article
  • Open Access
908 Views
20 Pages

The monolithic composite action of structures relies on the interface bond strength between concrete and the repair material. This study uses explainable deep learning techniques to evaluate the ultimate strength capacity (Us) of U-shaped normal conc...

  • Article
  • Open Access
4,984 Views
21 Pages

Current policy recommendations for initial teacher education encourage teaching code-related literacy (phonics, phonological awareness, and phonemic awareness) over pedagogical knowledge, and engaging practice in learning to read. To enhance early ch...

  • Review
  • Open Access
1 Citations
1,968 Views
12 Pages

Management of High Urogenital Sinus in Adults: A Scoping Review

  • Muhammed A. Moukhtar Hammad,
  • Nardeen Magdy Samaan and
  • Gamal Ghoniem

22 January 2025

Background and Objectives: Persistent urogenital sinus (PUGS) is a rare congenital anomaly resulting from disruptions in urogenital development during embryogenesis. Characterized by the confluence of the vaginal canal and urethra into a single chann...

  • Brief Report
  • Open Access
2 Citations
12,332 Views
9 Pages

Battle of the Sexes in Best of Breed: Sex Influences Dogs’ Success in the Show Ring

  • Bethany J. Wilson,
  • Alicia J. Kasbarian,
  • Navneet Dhand and
  • Paul D. McGreevy

18 December 2018

Much of the research on pedigree dog breeding has been directed towards understanding the implications of reduced genetic diversity and the prevalence of inherited disorders. An example is the potential role of the popular sire effect in perpetuating...