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493 Results Found

  • Article
  • Open Access
16 Citations
4,099 Views
20 Pages

Radon Mitigation Applications at the Laboratorio Subterráneo de Canfranc (LSC)

  • Javier Pérez-Pérez,
  • Julio Cesar Amare,
  • Iulian Catalin Bandac,
  • Alberto Bayo,
  • Silvia Borjabad-Sánchez,
  • Jose Maria Calvo-Mozota,
  • Laura Cid-Barrio,
  • Rebecca Hernández-Antolín,
  • Beatriz Hernández-Molinero and
  • Grzegorz Zuzel
  • + 9 authors

9 February 2022

The Laboratorio Subterráneo de Canfranc (LSC) is the Spanish national hub for low radioactivity techniques and the associated scientific and technological applications. The concentration of the airborne radon is a major component of the radioa...

  • Article
  • Open Access
6 Citations
3,932 Views
16 Pages

The Mechanism of Layer Stacked Clamping (LSC) for Polishing Ultra-Thin Sapphire Wafer

  • Zhixiang Chen,
  • Linlin Cao,
  • Julong Yuan,
  • Binghai Lyu,
  • Wei Hang and
  • Jiahuan Wang

6 August 2020

Double-sides polishing technology has the advantages of high flatness and parallelism, and high polishing efficiency. It is the preferred polishing method for the preparation of ultra-thin sapphire wafer. However, the clamping method is a fundamental...

  • Article
  • Open Access
2 Citations
2,204 Views
21 Pages

The water balance in the very shallow subsurface can be influenced by capillary rise due to a high groundwater table. Since moisture content is an important factor for the thermal conductivity of soils, this can also have an influence on the very sha...

  • Article
  • Open Access
5 Citations
2,545 Views
21 Pages

21 January 2023

The design, energetic performance, and thermal impact of large-scale geothermal collector systems (LSCs) are dependent on the thermal conductivity of unsaturated soils (λ). The aim of this study was to investigate the benefits of two different...

  • Article
  • Open Access
1 Citations
958 Views
12 Pages

Least Significant Change (LSC) for Serum Concentrations of 25-Hydroxyvitamin D

  • Pawel Pludowski,
  • Marek Wójcik,
  • Maciej Jaworski,
  • Agnieszka Ochocińska,
  • William B. Grant and
  • Michael F. Holick

7 July 2025

Background: The least significant change (LSC) method should be introduced and considered a proper method to define the smallest clinically important difference between two consecutive measurements. Methods: The LSC was calculated based on 150 patien...

  • Review
  • Open Access
45 Citations
7,029 Views
21 Pages

An Insight into the Difficulties in the Discovery of Specific Biomarkers of Limbal Stem Cells

  • Zhi Hou Guo,
  • Wei Zhang,
  • Yang Yan Sheng Jia,
  • Qing Xiu Liu,
  • Zhao Fa Li and
  • Jun Sheng Lin

Keeping the integrity and transparency of the cornea is the most important issue to ensure normal vision. There are more than 10 million patients going blind due to the cornea diseases worldwide. One of the effective ways to cure corneal diseases is...

  • Article
  • Open Access
5 Citations
2,758 Views
26 Pages

GOCE Downward Continuation to the Earth’s Surface and Improvements to Local Geoid Modeling by FFT and LSC

  • Dimitrios A. Natsiopoulos,
  • Elisavet G. Mamagiannou,
  • Eleftherios A. Pitenis,
  • Georgios S. Vergos and
  • Ilias N. Tziavos

10 February 2023

One of the main applications of the gravity field and steady-state Ocean Circulation Explorer (GOCE) satellite data is their combination with local gravity anomalies for geoid and gravity field modeling purposes. The aim of the present paper was the...

  • Review
  • Open Access
5 Citations
3,864 Views
26 Pages

5 November 2024

In this work, the recent achievements in the application of solid oxides fuel cells (SOFCs) are discussed. This paper summarizes the progress in two major topics: the materials for the electrolytes, anode, and cathode, and the fuels used, such as hyd...

  • Review
  • Open Access
12 Citations
3,967 Views
11 Pages

CD26/DPP-4 in Chronic Myeloid Leukemia

  • Anna Sicuranza,
  • Donatella Raspadori and
  • Monica Bocchia

11 February 2022

CD26 expression is altered in many solid tumors and hematological malignancies. Recently, it has been demonstrated that it is a specific marker expressed on LSCs of CML, both in BM and PB samples, and absent on CD34+/CD38− stem cells in normal...

  • Feature Paper
  • Article
  • Open Access
19 Citations
5,242 Views
10 Pages

Simulation of a Novel Configuration for Luminescent Solar Concentrator Photovoltaic Devices Using Bifacial Silicon Solar Cells

  • Mohammadreza Aghaei,
  • Marcello Nitti,
  • Ned J. Ekins-Daukes and
  • Angèle H.M.E. Reinders

28 January 2020

In this study, a novel configuration for luminescent solar concentrator photovoltaic (LSC PV) devices is presented, with vertically placed bifacial PV solar cells made of mono-crystalline silicon (mono c-Si). This LSC PV device comprises multiple rec...

  • Article
  • Open Access
9 Citations
3,048 Views
23 Pages

Detection of Limbal Stem Cells Adhered to Melt Electrospun Silk Fibroin and Gelatin-Modified Polylactic Acid Scaffolds

  • Emilija Zdraveva,
  • Krešo Bendelja,
  • Luka Bočkor,
  • Tamara Dolenec and
  • Budimir Mijović

3 February 2023

Limbal stem cells (LSCs) are of paramount importance in corneal epithelial tissue repair. The cornea becomes opaque in case of limbal stem cell deficiency (LSCD), which may cause serious damage to the ocular visual function. There are many techniques...

  • Article
  • Open Access
16 Citations
7,628 Views
27 Pages

Daytime Low Stratiform Cloud Detection on AVHRR Imagery

  • Jan Pawel Musial,
  • Fabia Hüsler,
  • Melanie Sütterlin,
  • Christoph Neuhaus and
  • Stefan Wunderle

5 June 2014

The near-real time retrieval of low stratiform cloud (LSC) coverage is of vital interest for such disciplines as meteorology, transport safety, economy and air quality. Within this scope, a novel methodology is proposed which provides the LSC occurre...

  • Article
  • Open Access
3 Citations
6,602 Views
21 Pages

The Role of Self-Control in Cyberbullying Bystander Behavior

  • Revital Sela-Shayovitz,
  • Michal Levy and
  • Jonathan Hasson

18 January 2024

The present study examined the association between general low self-control (LSC) and its three subcomponents: risk taking, self-centeredness, and impulsivity and various bystander behaviors of cyberbullying. The study utilized a bifactor modeling ap...

  • Review
  • Open Access
9 Citations
3,929 Views
18 Pages

Acute Myeloid Leukemia Stem Cells in Minimal/Measurable Residual Disease Detection

  • Kritika Srinivasan Rajsri,
  • Nainita Roy and
  • Sohini Chakraborty

22 May 2023

Acute myeloid leukemia (AML) is a hematological malignancy characterized by an abundance of incompletely matured or immature clonally derived hematopoietic precursors called leukemic blasts. Rare leukemia stem cells (LSCs) that can self-renew as well...

  • Review
  • Open Access
4 Citations
3,814 Views
24 Pages

Acute myeloid leukemia (AML) is the most common and incurable leukemia subtype. Despite extensive research into the disease’s intricate molecular mechanisms, effective treatments or expanded diagnostic or prognostic markers for AML have not yet...

  • Communication
  • Open Access
1,109 Views
13 Pages

22 October 2025

Efficient O2 transport through the ionomer film in cathode catalyst layers (CCLs) is a critical factor for the output performance of proton exchange membrane fuel cells (PEMFCs), yet the molecular mechanisms of gas transport in ionomers remain elusiv...

  • Article
  • Open Access
5 Citations
2,792 Views
22 Pages

2 December 2021

For distributed drive autonomous vehicles, adding lateral stability control (LSC) to the trajectory tracking control (TTC) can optimize the distribution of the driving torque of each wheel, so that the vehicle can track the planned trajectory while m...

  • Review
  • Open Access
6 Citations
5,067 Views
29 Pages

Acute myeloid leukemia (AML) is a rare subtype of acute leukemia in the pediatric and adolescent population but causes disproportionate morbidity and mortality in this age group. Standard chemotherapeutic regimens for AML have changed very little in...

  • Review
  • Open Access
16 Citations
6,401 Views
10 Pages

Understanding the Notch Signaling Pathway in Acute Myeloid Leukemia Stem Cells: From Hematopoiesis to Neoplasia

  • Daniel Láinez-González,
  • Juana Serrano-López and
  • Juan Manuel Alonso-Dominguez

12 March 2022

The Notch signaling pathway is fundamental to early fetal development, but its role in acute myeloid leukemia is still unclear. It is important to elucidate the function that contains Notch, not only in acute myeloid leukemia, but in leukemic stem ce...

  • Article
  • Open Access
7 Citations
2,696 Views
13 Pages

Leuconostoc Citreum Inhibits Adipogenesis and Lipogenesis by Inhibiting p38 MAPK/Erk 44/42 and Stimulating AMPKα Signaling Pathways

  • Hyo-Shim Han,
  • Ilavenil Soundharrajan,
  • Mariadhas Valan Arasu,
  • Dahye Kim and
  • Ki-Choon Choi

Probiotics provide a range of health benefits. Several studies have shown that using probiotics in obesity treatment can reduce bodyweight. However, such treatments are still restricted. Leuconostoc citreum, an epiphytic bacterium, is widely used in...

  • Review
  • Open Access
103 Citations
15,971 Views
40 Pages

Targeting PI3K/Akt/mTOR in AML: Rationale and Clinical Evidence

  • Salihanur Darici,
  • Hazem Alkhaldi,
  • Gillian Horne,
  • Heather G. Jørgensen,
  • Sandra Marmiroli and
  • Xu Huang

11 September 2020

Acute myeloid leukemia (AML) is a highly heterogeneous hematopoietic malignancy characterized by excessive proliferation and accumulation of immature myeloid blasts in the bone marrow. AML has a very poor 5-year survival rate of just 16% in the UK; h...

  • Article
  • Open Access
2 Citations
1,475 Views
16 Pages

Long-Term Reliability of Semi-Transparent Photovoltaic Panels Based on Luminescent Solar Concentrators

  • Giulio Mangherini,
  • Leonardo Sollazzo,
  • Valentina Diolaiti,
  • Malgorzata Gawronska,
  • Carla Sanna,
  • Alfonso Damiano and
  • Donato Vincenzi

31 January 2025

Long-term reliability is crucial for the commercialization of semi-transparent photovoltaic panels based on Luminescent Solar Concentrators (LSCs). This study addresses key challenges such as photodegradation and hail resistance using glazed LSC prot...

  • Article
  • Open Access
866 Views
30 Pages

14 November 2025

Dry Eye Disease (DED) is a multifactorial condition of the ocular surface, with one potential cause being damage from eye drops containing preservatives such as benzalkonium chloride (BAC). Current treatments for DED are unsatisfactory; therefore, it...

  • Article
  • Open Access
1 Citations
1,118 Views
16 Pages

Comparative Analysis of the Chloroplast Genomes of Cypripedium: Assessing the Roles of SSRs and TRs in the Non-Coding Regions of LSC in Shaping Chloroplast Genome Size

  • Huanchu Liu,
  • Hans Jacquemyn,
  • Yanlin Wang,
  • Yuanman Hu,
  • Xingyuan He,
  • Ying Zhang,
  • Yue Zhang,
  • Yanqing Huang and
  • Wei Chen

Cypripedium is renowned for its high morphological diversity and complex genetic and evolutionary characteristics. The chloroplast genome serves as a valuable tool for investigating phylogenetic relationships and evolutionary processes in plants. Cur...

  • Article
  • Open Access
8 Citations
7,636 Views
23 Pages

Live streaming commerce (LSC) effectively combines the traditional real economy and e-commerce. Based on more than half a million unique GIS data values on LSC activities sourced via Taobao (Alibaba), we traced the spatial distribution of different p...

  • Article
  • Open Access
7 Citations
3,751 Views
21 Pages

10 July 2018

Recently, low-frequency oscillation (LFO) has occurred many times in high-speed railways and has led to traction blockades. Some of the literature has found that the stability of the vehicle-grid coupling system could be improved by optimizing the co...

  • Article
  • Open Access
5 Citations
3,693 Views
16 Pages

18 November 2019

High-precision, high-reliability, and high-density GPS crustal velocity are extremely important requirements for geodynamic analysis. The least-squares collocation algorithm (LSC) has unique advantages over crustal movement models to overcome observa...

  • Article
  • Open Access
3 Citations
1,950 Views
14 Pages

Tyrosine Kinase Inhibitor Therapy Enhances Stem Cells Profile and May Contribute to Survival of Chronic Myeloid Leukemiastem Cells

  • Simone Rocco,
  • Alessandro Maglione,
  • Valentina Schiavo,
  • Alessandro Ferrando,
  • Carmen Fava,
  • Daniela Cilloni,
  • Barbara Pergolizzi and
  • Cristina Panuzzo

10 January 2025

Background/Objectives: Treatment with tyrosine kinase inhibitors (TKIs) in chronic myeloid leukemia (CML) has revolutionized disease management and has transformed CML from a life-threatening disease to a chronic condition for many patients. However,...

  • Review
  • Open Access
4 Citations
3,008 Views
15 Pages

A Leukemic Target with a Thousand Faces: The Mitochondria

  • Beatrice Maffeo,
  • Cristina Panuzzo,
  • Amedeo Moraca and
  • Daniela Cilloni

22 August 2023

In the era of personalized medicine greatly improved by molecular diagnosis and tailor-made therapies, the survival rate of acute myeloid leukemia (AML) at 5 years remains unfortunately low. Indeed, the high heterogeneity of AML clones with distinct...

  • Article
  • Open Access
2 Citations
2,784 Views
18 Pages

Persistence of Chronic Lymphocytic Leukemia Stem-like Populations under Simultaneous In Vitro Treatment with Curcumin, Fludarabine, and Ibrutinib: Implications for Therapy Resistance

  • Àngel Bistué-Rovira,
  • Laura G. Rico,
  • Jorge Bardina,
  • Jordi Juncà,
  • Isabel Granada,
  • Jolene A. Bradford,
  • Michael D. Ward,
  • Roser Salvia,
  • Francesc Solé and
  • Jordi Petriz

7 February 2024

Leukemic stem cells (LSCs) possess similar characteristics to normal hematopoietic stem cells, including self-renewal capacity, quiescence, ability to initiate leukemia, and drug resistance. These cells play a significant role in leukemia relapse, pe...

  • Article
  • Open Access
5 Citations
3,012 Views
19 Pages

Groundwater temperature (GWT) is usually measured using screened monitoring wells (MWs). The aim of this study was to investigate whether MWs are suitable for monitoring the effects of large-scale geothermal collector systems (LSCs) on GWT, focusing...

  • Article
  • Open Access
10 Citations
3,325 Views
13 Pages

In recent years, the ultra-dense low Earth orbit (LEO) satellite communication (UD-LSC) networks such as SpaceX and OneWeb are under rapid development to provide worldwide and broadband services. However, the deployment of thousands of LEO satellites...

  • Communication
  • Open Access
23 Citations
2,522 Views
10 Pages

Minimal Residual Disease Detection at RNA and Leukemic Stem Cell (LSC) Levels: Comparison of RT-qPCR, d-PCR and CD26+ Stem Cell Measurements in Chronic Myeloid Leukemia (CML) Patients in Deep Molecular Response (DMR)

  • Elisabetta Abruzzese,
  • Monica Bocchia,
  • Malgorzata Monika Trawinska,
  • Donatella Raspadori,
  • Francesco Bondanini,
  • Anna Sicuranza,
  • Paola Pacelli,
  • Federica Re,
  • Alessia Cavalleri and
  • Simona Bernardi
  • + 4 authors

15 August 2023

A Deep Molecular Response (DMR), defined as a BCR::ABL1 transcript at levels ≤ 0.01% by RT-qPCR, is the prerequisite for the successful interruption of treatment among patients with Chronic Myeloid Leukemia (CML). However, approximately 50% of pat...

  • Article
  • Open Access
10 Citations
2,599 Views
17 Pages

The Reliability of PCL/Anti-VEGF Electrospun Scaffolds to Support Limbal Stem Cells for Corneal Repair

  • Emilija Zdraveva,
  • Tamara Dolenec,
  • Mirna Tominac Trcin,
  • Emi Govorčin Bajsić,
  • Tamara Holjevac Grgurić,
  • Antoneta Tomljenović,
  • Iva Dekaris,
  • Josip Jelić and
  • Budimir Mijovic

13 June 2023

Since only few reported studies propose anti-vascular endothelial growth factor (anti-VEGF) delivery through electrospun scaffolds, this study greatly contributes to the potential prevention of patient’s vision loss, as it explores electrospun...

  • Review
  • Open Access
22 Citations
10,515 Views
35 Pages

Location First: Targeting Acute Myeloid Leukemia Within Its Niche

  • Alice Pievani,
  • Marta Biondi,
  • Chiara Tomasoni,
  • Andrea Biondi and
  • Marta Serafini

Despite extensive research and development of new treatments, acute myeloid leukemia (AML)-backbone therapy has remained essentially unchanged over the last decades and is frequently associated with poor outcomes. Eradicating the leukemic stem cells...

  • Article
  • Open Access
6 Citations
3,332 Views
15 Pages

19 December 2024

This research addresses the need for enhanced thermal management in building-integrated photovoltaic systems, specifically focusing on semi-transparent PV panels based on luminescent solar concentrator (LSC) technology. In pursuit of optimal thermal...

  • Review
  • Open Access
8 Citations
4,456 Views
10 Pages

26 October 2022

The complexity of the bone marrow (BM) microenvironment makes studying hematological malignancies in vitro a challenging task. Three-dimensional cell cultures are being actively studied, particularly due to their ability to serve as a bridge of the g...

  • Review
  • Open Access
12 Citations
4,901 Views
12 Pages

Understanding the Wnt Signaling Pathway in Acute Myeloid Leukemia Stem Cells: A Feasible Key against Relapses

  • Daniel Láinez-González,
  • Ana Belén Alonso-Aguado and
  • Juan Manuel Alonso-Dominguez

Wnt signaling is a highly conserved pathway in evolution which controls important processes such as cell proliferation, differentiation and migration, both in the embryo and in the adult. Dysregulation of this pathway can favor the development of dif...

  • Article
  • Open Access
8 Citations
4,126 Views
20 Pages

Involvement of ORAI1/SOCE in Human AML Cell Lines and Primary Cells According to ABCB1 Activity, LSC Compartment and Potential Resistance to Ara-C Exposure

  • Clara Lewuillon,
  • Aurélie Guillemette,
  • Sofia Titah,
  • Faruk Azam Shaik,
  • Nathalie Jouy,
  • Ossama Labiad,
  • Valerio Farfariello,
  • Marie-Océane Laguillaumie,
  • Thierry Idziorek and
  • Yasmine Touil
  • + 7 authors

Acute myeloid leukemia (AML) is a hematological malignancy with a high risk of relapse. This issue is associated with the development of mechanisms leading to drug resistance that are not yet fully understood. In this context, we previously showed th...

  • Review
  • Open Access
38 Citations
10,009 Views
30 Pages

14 October 2022

In the past decade, there has been an increase in the environmental performance assessment in earth construction through the life cycle assessment (LCA) methodology. A Systematic Literature Review verified LCA methodology trends of five earth constru...

  • Article
  • Open Access
4 Citations
5,178 Views
11 Pages

26 February 2023

Background: The “Guidelines for the Management of Specific Learning Disorders” provide clear diagnostic and evaluative guidance on Reading Comprehension Disorder (RCD), as suggested by the DSM-5. The present study investigated the relatio...

  • Article
  • Open Access
3 Citations
2,722 Views
15 Pages

Glass Substrate Dust Removal Using 233 fs Laser-Generated Shockwave

  • Myeongjun Kim,
  • Philgong Choi,
  • Jae Heung Jo and
  • Kyunghan Kim

10 November 2021

Eliminating dust is gaining importance as a critical requirement in the display panel manufacturing process. The pixel resolution of display panels is increasing rapidly, which means that even small dust particles on the order of a few micrometers ca...

  • Article
  • Open Access
13 Citations
3,309 Views
13 Pages

2 April 2020

The research aims to describe the micro-machining characteristics in a high-speed magnetic abrasive finishing, which is applicable for achieving the high surface accuracy and dimensional accuracy of fine ceramic bars that are typically characterized...

  • Article
  • Open Access
7 Citations
2,777 Views
15 Pages

A Superimposed QD-Based Optical Antenna for VLC: White LED Source

  • Shaghayegh Chamani,
  • Ali Rostami and
  • Peyman Mirtaheri

27 July 2022

Visible light communication (VLC) is a versatile enabling technology for following high-speed wireless communication because of its broad unlicensed spectrum. In this perspective, white light-emitting diodes (LED) provide both illumination and data t...

  • Article
  • Open Access
7 Citations
2,492 Views
19 Pages

Automatic ROI Setting Method Based on LSC for a Traffic Congestion Area

  • Yang He,
  • Lisheng Jin,
  • Huanhuan Wang,
  • Zhen Huo,
  • Guangqi Wang and
  • Xinyu Sun

2 December 2022

Congested regions in videos put forward higher requirements for target detection algorithms, and the key detection of congested regions provides optimization directions for improving the accuracy of detection algorithms. In order to make the target d...

  • Review
  • Open Access
65 Citations
8,671 Views
22 Pages

Review of Core/Shell Quantum Dots Technology Integrated into Building’s Glazing

  • Amira R. AbouElhamd,
  • Khaled A. Al-Sallal and
  • Ahmed Hassan

19 March 2019

Skylights and windows are building openings that enhance human comfort and well-being in various ways. Recently, a massive drive is witnessed to replace traditional openings with building integrated photovoltaic (BIPV) systems to generate power in a...

  • Article
  • Open Access
1 Citations
2,860 Views
21 Pages

Variable-Scale Visualization of High-Density Polygonal Buildings on a Tile Map

  • Zhixiong Chen,
  • Yilang Shen,
  • Xinlin Lv,
  • Qiaolin Qin and
  • Xin Chen

To better satisfy user’s needs for the accurate visualization of massive amounts of geographic data, the variable-scale expression of map content based on multilevel data organization has attracted increasing attention. Traditional methods base...

  • Article
  • Open Access
4 Citations
4,290 Views
22 Pages

A Practicable Guideline for Predicting the Thermal Conductivity of Unconsolidated Soils

  • David Bertermann,
  • Mario Rammler,
  • Mark Wernsdorfer and
  • Hannes Hagenauer

For large infrastructure projects, such as high-voltage underground cables or for evaluating the very shallow geothermal potential (vSGP) of small-scale horizontal geothermal systems, large-scale geothermal collector systems (LSCs), and fifth generat...

  • Article
  • Open Access
9 Citations
3,836 Views
14 Pages

Synthesis and Spectroscopic Characterization of Thienopyrazine-Based Fluorophores for Application in Luminescent Solar Concentrators (LSCs)

  • Xheila Yzeiri,
  • Massimo Calamante,
  • Alessio Dessì,
  • Daniele Franchi,
  • Andrea Pucci,
  • Francesco Ventura,
  • Gianna Reginato,
  • Lorenzo Zani and
  • Alessandro Mordini

7 September 2021

Organic fluorophores have found broad application as emitters in luminescent solar concentrators (LSCs) for silicon photovoltaics. In particular, the preparation of organic conjugated systems with intense light-harvesting ability, emissions in the de...

  • Article
  • Open Access
5 Citations
2,389 Views
22 Pages

Intelligent Segmentation and Change Detection of Dams Based on UAV Remote Sensing Images

  • Haimeng Zhao,
  • Xiaojian Yin,
  • Anran Li,
  • Huimin Zhang,
  • Danqing Pan,
  • Jinjin Pan,
  • Jianfang Zhu,
  • Mingchun Wang,
  • Shanlin Sun and
  • Qiang Wang

27 November 2023

Guilin is situated in the southern part of China with abundant rainfall. There are 137 reservoirs, which are widely used for irrigation, flood control, water supply and power generation. However, there has been a lack of systematic and full-coverage...

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