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950 Results Found

  • Article
  • Open Access
19 Citations
3,532 Views
17 Pages

Presenting diet quality of patients with metabolic syndrome (MetS), using a holistic approach is more useful than investigating dietary individual components, but there is still a small amount of research in this area. The aim of this study assessed...

  • Article
  • Open Access
110 Citations
17,066 Views
12 Pages

Higher HEI-2015 Score Is Associated with Reduced Risk of Depression: Result from NHANES 2005–2016

  • Kai Wang,
  • Yudi Zhao,
  • Jiaqi Nie,
  • Haoling Xu,
  • Chuanhua Yu and
  • Suqing Wang

25 January 2021

Globally, the total estimated number of people living with depression increased by 18.4% between 2005 and 2015, with the prevalence being 4.8% in 2015. Many nutrient and diet patterns are proven to be correlated to depression, so we conducted this an...

  • Article
  • Open Access
13 Citations
5,928 Views
13 Pages

17 December 2020

Amid the strain related to the necessity of distance learning and related organizational adjustments in higher education institutions (HEIs), this paper re-examines the problem-focused coping strategy and its efficiency in addressing work-related str...

  • Article
  • Open Access
2,161 Views
26 Pages

Notch-Dependent Expression of the Drosophila Hey Gene Is Supported by a Pair of Enhancers with Overlapping Activities

  • Maria Monastirioti,
  • Ioanna Koltsaki,
  • Ioanna Pitsidianaki,
  • Emilia Skafida,
  • Nikolaos Batsiotos and
  • Christos Delidakis

14 August 2024

Drosophila Hey is a basic helix–loop–helix–orange (bHLH-O) protein with an important role in the establishment of distinct identities of postmitotic cells. We have previously identified Hey as a transcriptional target and effector o...

  • Article
  • Open Access
7 Citations
5,004 Views
18 Pages

Identification and Prioritization of Lean Waste in Higher Education Institutions (HEI): A Proposed Framework

  • Ig. Jaka Mulyana,
  • Moses Laksono Singgih,
  • Sri Gunani Partiwi and
  • Yustinus Budi Hermanto

28 January 2023

Waste in HEIs is difficult to identify, so identifying and prioritizing waste is challenging. This research aims to develop a framework within which to identify and prioritize waste reduction in HEIs. The novelty of this study is that it analyzes and...

  • Article
  • Open Access
5 Citations
3,503 Views
17 Pages

Analysis of UNESCO ESD Priority Areas’ Implementation in Romanian HEIs

  • Corina-Ionela Dumitrescu,
  • Georgiana Moiceanu,
  • Razvan-Mihai Dobrescu and
  • Mirona Ana Maria Popescu

Higher education institutions (HEIs) are adopting sustainable development (SD) in their strategies for the future. The roadmap by UNESCO is the path to follow to reach success. The approach is different for every HEI, thus the objective of this paper...

  • Article
  • Open Access
7 Citations
5,394 Views
11 Pages

rLj-RGD3 Suppresses the Growth of HeyA8 Cells in Nude Mice

  • Yuanyuan Zheng,
  • Li Lv,
  • Longda Yi,
  • Rui Wu,
  • Rong Xiao and
  • Jihong Wang

15 December 2017

In the previous study, rLj-RGD3, a recombinant toxin protein which contains three RGD motifs, was reported to not only inhibit the proliferation of an ovarian cancer cell line, HeyA8 cells, by inducing apoptosis, but also block their adhesion, migrat...

  • Article
  • Open Access
11 Citations
4,596 Views
13 Pages

Impaired Glycolysis Promotes Alcohol Exposure-Induced Apoptosis in HEI-OC1 Cells via Inhibition of EGFR Signaling

  • Hyunsook Kang,
  • Seong Jun Choi,
  • Kye Hoon Park,
  • Chi-Kyou Lee and
  • Jong-Seok Moon

Glucose metabolism is an important metabolic pathway in the auditory system. Chronic alcohol exposure can cause metabolic dysfunction in auditory cells during hearing loss. While alcohol exposure has been linked to hearing loss, the mechanism by whic...

  • Article
  • Open Access
26 Citations
4,792 Views
12 Pages

19 February 2022

Whether there is an association between dietary quality and sleep disorder in American adults is unclear. We conducted this study to analyze whether dietary quality, using the Healthy Eating Index-2015 (HEI-2015) scores as the measure, was associated...

  • Article
  • Open Access
2,907 Views
24 Pages

14 November 2024

The antidiabetic drugs metformin, glipizide and gliclazide have been used for many years to control blood glucose levels. In recent years, they have gained importance in non-diabetic pharmacological purposes including cancer and hearing loss treatmen...

  • Article
  • Open Access
4 Citations
3,065 Views
24 Pages

Modeling of the Factors of Higher Education Institutions (HEIs) Influencing the Strategic Linking Decisions with the Industrial Sector: Whole-Institution Approach

  • Karina Cecilia Arredondo-Soto,
  • Jean Paul Serrano-Manrrique,
  • Julio Blanco-Fernandez,
  • Guadalupe Hernández-Escobedo,
  • Marco Augusto Miranda-Ackerman and
  • Jorge Luis García-Alcaraz

12 April 2020

Higher Education Institutions (HEIs) are dedicated to the professionalization of human capital; to accomplish this, the link with the productive sector is an active component that must be strengthened through formal mechanisms. The purpose of this pa...

  • Article
  • Open Access
17 Citations
5,165 Views
23 Pages

24 July 2022

Interest in plant-based nutrition has steadily increased in the western world in the recent years. The number of people following a meat-reduced, flexitarian diet is growing continuously. However, little is known about the diet quality of flexitarian...

  • Article
  • Open Access
9 Citations
6,993 Views
43 Pages

8 March 2022

A rapid spread of the COVID-19 outbreak has recently shifted teaching and learning at higher education institutions (HEIs) worldwide from the traditional classroom to the online process. During the educational disruption, online teaching and learning...

  • Article
  • Open Access
12 Citations
3,649 Views
11 Pages

26 October 2021

Educational needs are changing worldwide. Social aspects and the impact of knowledge and education on changing society are already taken into consideration from some viewpoints. However, the social impact of different models of education that bring n...

  • Article
  • Open Access
1,071 Views
21 Pages

Azvudine Suppresses Epithelial–Mesenchymal Transition in Hepatocellular Carcinoma by Targeting the Notch–HEY Signalling Pathway

  • Yao Meng,
  • Peiyi Sun,
  • Yixin Ren,
  • Guoqing Li,
  • Xiujun Liu,
  • Chunjie Xu,
  • Luyao Dong,
  • Hanhan Li,
  • Zhonghui Zheng and
  • Xinyi Yang

Azvudine (FNC) is a novel cytidine analogue that is widely used in the treatment of infectious diseases such as AIDS and COVID-19. Previous studies have demonstrated its anticancer activity in various cancer cell lines, including non-Hodgkin’s lympho...

  • Article
  • Open Access
21 Citations
7,222 Views
24 Pages

12 September 2019

In the last years, a shift in the promotion of sustainable development in Higher Education from a focus on universities’ core areas of teaching and research to “whole institution approaches” with an emphasis on the operational manag...

  • Article
  • Open Access
4 Citations
3,829 Views
22 Pages

Did the Quality of Digital Communication Skills in Education Improve after the Pandemic? Evidence from HEIs

  • Anna Urbanek,
  • Anna Losa,
  • Monika Wieczorek-Kosmala,
  • Karel Hlaváček and
  • Aleš Lokaj

2 August 2023

In the global transition, digital technologies are perceived as important drivers of change. Contemporary IT technologies help to enhance the productivity and efficiency of numerous systems on the way to achieving sustainable development goals. Wider...

  • Article
  • Open Access
4 Citations
2,880 Views
21 Pages

HOCI Probe CPP Induces the Differentiation of Human Dermal Fibroblasts into Vascular Endothelial Cells through PHD2/HIF-1α/HEY1 Signaling Pathway

  • Xiaoling Cui,
  • Jie Wen,
  • Nan Li,
  • Xuxiao Hao,
  • Shangli Zhang,
  • Baoxiang Zhao,
  • Xunwei Wu and
  • Junying Miao

4 October 2022

Human dermal fibroblasts (HDFs) have the potential to differentiate into endothelial cells (VECs). In our previous research, we reported that a hypochlorous acid (HOCl) probe CPP efficiently induced the differentiation of HDFs into VECs, however, the...

  • Article
  • Open Access
3 Citations
3,148 Views
18 Pages

Effects of Nutraceuticals on Cisplatin-Induced Cytotoxicity in HEI-OC1 Cells

  • Lorenzo Guidotti,
  • Elena Tomassi,
  • Silvia Marracci,
  • Michele Lai,
  • Dominga Lapi,
  • Rossana Pesi,
  • Laura Pucci,
  • Ettore Novellino,
  • Elisabetta Albi and
  • Mercedes Garcia-Gil

12 December 2023

Cisplatin is a chemotherapeutic drug for the treatment of several solid tumors, whose use is limited by its nephrotoxicity, neurotoxicity, ototoxicity, and development of resistance. The toxicity is caused by DNA cross-linking, increase in reactive o...

  • Article
  • Open Access
3 Citations
2,481 Views
14 Pages

1 September 2022

Lipid transporter protein apolipoprotein E (APOE) has contributed to functional studies of various organ functions. Animals with ApoE knockout (KO) have been used to study atherosclerosis and hyperlipidemia while an increasing number of researchers h...

  • Article
  • Open Access
765 Views
14 Pages

Association Analysis of the FTO Gene Polymorphisms with Growth and Carcass Traits of Heying Black Chicken and Tissue Expression Profile

  • Hao Ding,
  • Lan Chen,
  • Can Chen,
  • Tao Zhang,
  • Weilin Chen,
  • Genxi Zhang,
  • Jinyu Wang and
  • Kaizhou Xie

17 September 2025

Fat volume and obesity-related genes (e.g., the FTO gene) are important candidate genes affecting energy metabolism. Single nucleotide polymorphisms (SNPs) in the FTO gene are associated with carcass, growth and meat quality traits of pigs, cattle, s...

  • Article
  • Open Access
51 Citations
9,697 Views
19 Pages

21 August 2017

The Healthy Eating Index (HEI) is a diet quality index shown to be associated with reduced chronic disease risk. Older versions of the HEI have been adapted for Canadian populations; however, no Canadian modification of the Healthy Eating Index-2010...

  • Article
  • Open Access
15 Citations
5,350 Views
14 Pages

Associations of Pre-Defined Dietary Patterns with Obesity Associated Phenotypes in Tehranian Adolescents

  • Sahar Mohseni-Takalloo,
  • Firoozeh Hosseini-Esfahani,
  • Parvin Mirmiran and
  • Fereidoun Azizi

18 August 2016

Obesity has become a public health problem in adolescents and could be a risk factor for both short-term and long-term health consequences. This study aimed to evaluate the relationship of Dietary Guidelines for Americans Adherence Index (DGAI), Heal...

  • Article
  • Open Access
13 Citations
5,635 Views
13 Pages

15 September 2017

Terrestrial vegetation dynamics are closely influenced by both hydrological process and climate change. This study investigated the relationships between vegetation pattern and hydro-meteorological elements. The joint entropy method was employed to e...

  • Article
  • Open Access
1,292 Views
22 Pages

Rates of Mitochondrial Metabolism of Glucose, Amino Acids, and Fatty Acids by the HEI-OC1 Inner Ear Cell Line

  • Kento Koda,
  • Teru Kamogashira,
  • Ken Hayashi,
  • Chisato Fujimoto,
  • Shinichi Iwasaki,
  • Tatsuya Yamasoba and
  • Kenji Kondo

24 August 2025

Background: Mitochondrial substrate switching plays an important role in aging. The substrate metabolic rate is closely related to mitochondrial activity, as mitochondria are the primary site for substrate oxidation and ATP production. Different subs...

  • Article
  • Open Access
16 Citations
4,042 Views
16 Pages

Few studies have examined the dietary intake of low-income pregnant women participating in the Special Supplemental Nutrition Program for Women, Infants, and Children (WIC). The aim of this study was to assess the dietary quality of WIC-enrolled preg...

  • Brief Report
  • Open Access
1,147 Views
13 Pages

Validation of the Texas School Physical Activity and Nutrition (SPAN) Dietary Index Against the Healthy Eating Index Among Elementary-Aged Students

  • Ethan T. Hunt,
  • Allison N. Marshall,
  • Raja Malkani,
  • Nalini Ranjit,
  • Adriana Pérez,
  • David J. Badillo,
  • Danielle J. Gartner,
  • Ashley Schelfhout,
  • Vijay R. Narayanan and
  • Deanna M. Hoelscher

10 June 2025

Objective: Assess the accuracy of the Texas School Physical Activity and Nutrition (SPAN) survey’s diet quality index against the 24 h recall-based Healthy Eating Index (HEI-2020). Methods: Fifty-one rising third and fourth graders (mean age 9....

  • Article
  • Open Access
2 Citations
2,402 Views
12 Pages

Association between the Healthy Eating Index-2015 and Developmental Disabilities in Children: A Cross-Sectional Analysis

  • Jianxiong Gui,
  • Lingman Wang,
  • Ziyao Han,
  • Ran Ding,
  • Xiaoyue Yang,
  • Jiaxin Yang,
  • Hanyu Luo,
  • Dishu Huang,
  • Jie Liu and
  • Li Jiang

21 September 2023

Few studies have examined the association between dietary quality and the risk of developmental disabilities (DDs). This study aimed to investigate the association between dietary quality and the risk of DDs in US children aged 5 to 15. We employed d...

  • Article
  • Open Access
11 Citations
4,738 Views
11 Pages

31 August 2021

Due to the transition process in Croatia that started about three decades ago, higher education institutions (HEIs) are forced to intensively involve themselves in market competition and become market and entrepreneurial oriented in order to keep up...

  • Article
  • Open Access
1,063 Views
23 Pages

National Context Impacts on SDG Mapping Needs and Approaches in Higher Education, a Tri-National Comparison

  • Morgane Bousquet,
  • Ashley Byrne,
  • Daniel Forget,
  • Georgina Gough,
  • Louis-René Rheault,
  • Stéphane Roche and
  • David Siaussat

16 July 2025

Since 2015 and the Paris Agreements, several countries have committed to sustainable development (SD) and the Sustainable Development Goals (SDGs). Higher Education Institutions (HEIs) have an important role to play in providing education and support...

  • Article
  • Open Access
6 Citations
4,670 Views
28 Pages

Transforming Higher-Education-Intitutes: Impact of Change Management on Sustainable Performance Through Transformational Leadership and Knowledge Management

  • Shahawati Binti Umar,
  • Jawaria Ahmad,
  • Muhammad Anas Bin Mohd Bukhori,
  • Khairul Anuar Mohd Ali and
  • Wan Mohd Hirwani Wan Hussain

11 March 2025

Change management plays a key role in enhancing sustainable organizational performance in a dynamic global business environment. This study investigates the dimensions of change management (i.e., readiness of change, climate for change, and change pr...

  • Article
  • Open Access
46 Citations
9,595 Views
24 Pages

Development and Validation of the Short Healthy Eating Index Survey with a College Population to Assess Dietary Quality and Intake

  • Sarah Colby,
  • Wenjun Zhou,
  • Chelsea Allison,
  • Anne E. Mathews,
  • Melissa D. Olfert,
  • Jesse Stabile Morrell,
  • Carol Byrd-Bredbenner,
  • Geoffrey Greene,
  • Onikia Brown and
  • Karla Shelnutt

27 August 2020

Because diet quality (DQ) is associated with risk of chronic disease and is a common construct assessed in health-related research, validated tools to assess DQ are needed that have low respondent and researcher burden. Thus, content experts develop...

  • Review
  • Open Access
2,939 Views
33 Pages

16 July 2025

Higher education institutions (HEIs) are increasingly called upon to both respond to and drive societal change. To better understand how HEIs can enhance their ability to innovate, an integrative literature review was conducted, examining the concept...

  • Article
  • Open Access
10 Citations
6,505 Views
18 Pages

6 April 2022

Lean management has generated new approaches to reduce non-value-adding activities in different sectors of the economy, including in higher education systems. Lean principles in higher education institutions (HEIs) contribute positively to sustainabi...

  • Review
  • Open Access
7 Citations
3,542 Views
20 Pages

14 October 2023

This study focuses on the use of urban living labs (ULLs) as a teaching and learning strategy toward education for sustainable development (ESD) in higher education institutions (HEIs). The article presents an exhaustive literature review on the ESD...

  • Article
  • Open Access
27 Citations
9,420 Views
23 Pages

7 January 2021

This research reviews and analyzes prior corporate social responsibility (CSR) studies centered on its implications and disclosure in higher education institutions (HEIs). Nine major databases were analyzed to review research articles from various bu...

  • Article
  • Open Access
5 Citations
3,791 Views
12 Pages

Canadians Adults Fail Their Dietary Quality Examination Twice

  • Gerard Ngueta,
  • Caty Blanchette,
  • Myrto Mondor,
  • Jean-Claude Moubarac and
  • Michel Lucas

26 January 2023

For many years, dietary quality among Canadians has been assessed using an index that gives criticized scores and does not allow for comparison with Americans. In Canadians aged ≥19 years, we aimed to (1) determine the dietary quality by using a m...

  • Article
  • Open Access
11 Citations
4,057 Views
17 Pages

19 April 2017

This paper divides the typical social scientific research process into two stages: the research development stage and the research innovation stage, with personnel as a shared input between them. We construct an input-shared multi-period two-stage DE...

  • Article
  • Open Access
35 Citations
7,870 Views
30 Pages

12 August 2020

Higher education institutions (HEIs) in both early and mature stages of sustainable development (SD) have been moving toward sustainability. Methods for assessing SD have been developed from global and regional contexts to support sustainability effo...

  • Article
  • Open Access
25 Citations
5,318 Views
12 Pages

Pre-Pregnancy BMI Influences the Association of Dietary Quality and Gestational Weight Gain: The SECOST Study

  • Heng Yaw Yong,
  • Zalilah Mohd Shariff,
  • Barakatun Nisak Mohd Yusof,
  • Zulida Rejali,
  • Yvonne Yee Siang Tee,
  • Jacques Bindels and
  • Eline M. van der Beek

Poor diet quality in pregnancy could impact gestational weight gain (GWG) and consequently fetal growth and development. But today there is limited data available on gestational diet quality. This study investigated the association between diet quali...

  • Article
  • Open Access
13 Citations
3,990 Views
12 Pages

26 January 2023

In order to explore the relationship between the Healthy Eating Index (HEI-2015) and cardiovascular disease (CVD), and the mediating role of obesity and depressive symptoms, we used the data from the 2011–2018 National Health and Nutrition Exam...

  • Article
  • Open Access
15 Citations
5,568 Views
11 Pages

Mediating Bullying and Strain in Higher Education Institutions: The Case of Pakistan

  • Ambreen Anjum,
  • Amina Muazzam,
  • Farkhanda Manzoor,
  • Anna Visvizi and
  • Raheel Nawaz

15 April 2019

Although workplace bullying is a well-researched phenomenon, the specific way it unfolds in higher education institutions (HEI) remains largely underdiscussed. Based on the outcomes of a survey conducted across HEI in Pakistan, by reference to struct...

  • Article
  • Open Access
25 Citations
10,548 Views
19 Pages

Performance Appraisal in Universities—Assessing the Tension in Public Service Motivation (PSM)

  • Łukasz Sułkowski,
  • Sylwia Przytuła,
  • Colin Borg and
  • Konrad Kulikowski

Performance appraisal (PA) has become a prominent feature on the agenda of higher education institutions (HEIs). However, the traditional culture of the typical university is based on individual commitment, scientific teamwork, dedication to public s...

  • Article
  • Open Access
3 Citations
2,528 Views
16 Pages

26 April 2024

This study analyzed the social media communication of six higher education institutions (HEIs) in Poland during the COVID-19 pandemic within the context of university social responsibility (USR). The study used a mixed-method approach, conducting bot...

  • Article
  • Open Access
38 Citations
7,181 Views
23 Pages

Despite the many benefits of blockchain technology in higher education, this technology is not widely adopted by Higher Education Institutions (HEIs). Therefore, instead of providing additional motives for adopting blockchain technology, this researc...

  • Article
  • Open Access
41 Citations
7,164 Views
27 Pages

16 November 2020

Cloud-based technology, which is now well established, helps in reducing costs and providing accessibility, reliability and flexibility. However, the Yemen higher educational institutions (HEIs) have not yet embraced the technology due to security an...

  • Proceeding Paper
  • Open Access
31 Citations
4,888 Views
7 Pages

Sustainability Assessment of Higher Education Institutions: A Systematic Literature Review

  • Alok Bihari Singh,
  • Himanshu Kumar Meena,
  • Chandni Khandelwal and
  • Govind Sharan Dangayach

Higher education institutions (HEIs) are crucial social organizations that foster innovation, disseminate knowledge, and train future leaders in various fields. Higher education institutions are essential for implementing the Education for Sustainabl...

  • Article
  • Open Access
18 Citations
4,512 Views
19 Pages

Competences for Strengthening Entrepreneurial Capabilities in Europe

  • Tatjana Ņikitina,
  • Inga Lapiņa,
  • Modris Ozoliņš,
  • Madara Mara Irbe,
  • Martijn Priem,
  • Matthijs Smits and
  • Mikhail Nemilentsev

Authors in previous studies pointed out that the professional competences of managers overlap with the competences and skills that are attributed to entrepreneurs. The goal of this study is to analyze the correlation between the actual market demand...

  • Article
  • Open Access
5 Citations
3,270 Views
14 Pages

Caregiver Status and Diet Quality in Community-Dwelling Adults

  • Sharmin Hossain,
  • May A. Beydoun,
  • Michele K. Evans,
  • Alan B. Zonderman and
  • Marie F. Kuczmarski

26 May 2021

Objective: We investigated cross-sectional and longitudinal associations of diet quality with middle-aged caregiver status. Methods: Caregiving in the Healthy Aging in Neighborhoods of Diversity across the Life Span (HANDLS) study (57.7% women, 62% A...

  • Article
  • Open Access
33 Citations
7,056 Views
16 Pages

21 October 2019

We examined the reproducibility and relative validity of two measures of overall diet quality, the Healthy Eating Index-2015 (HEI-2015) and Nutrient-Rich Food Index 9.3 (NRF9.3), as estimated by well-established self-administered dietary assessment q...

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