- Article
Synthesis, ADMET Properties, and In Vitro Antimicrobial and Antibiofilm Activity of 5-Nitro-2-thiophenecarbaldehyde N-((E)-(5-Nitrothienyl)methylidene)hydrazone (KTU-286) against Staphylococcus aureus with Defined Resistance Mechanisms
- Povilas Kavaliauskas,
- Birute Grybaite,
- Vytautas Mickevicius,
- Ruta Petraitiene,
- Ramune Grigaleviciute,
- Rita Planciuniene,
- Philip Gialanella,
- Alius Pockevicius and
- Vidmantas Petraitis
The emergence of drug-resistant Staphylococcus aureus is responsible for high morbidity and mortality worldwide. New therapeutic options are needed to fight the increasing antimicrobial resistance among S. aureus in the clinical setting. We, therefor...