162 Results Found

Drought can seriously hinder the growth of plants, resulting in reduced crop yield and quality. At present, the tolerance of DEAD-box helicases (DHC) to abiotic stresses, such as drought, high salinity, low temperature, and high temperature, has been...

This paper presents a novel 400 V–50 V bidirectional DHC-LT resonant DC-DC converter. By adding a resonant capacitor and an auxiliary transformer based on LLC, zero-voltage switching (ZVS) and zero-current switching (ZCS) are achieved, while th...

Dynein is a multi-subunit motor protein that moves toward the minus-end of microtubules, and plays important roles in fly development. We identified Dhc64Cm115, a new mutant allele of the fly Dynein heavy chain 64C (Dhc64C) gene whose heterozygotes s...

Smith–Lemli–Opitz syndrome (SLOS) is a developmental disability arising from bi-allelic pathogenic variants in the 7-dehydrocholestrol reductase (DHCR7) enzyme and the accumulation of 7-dehydrocholesterol (7-DHC). 7-DHC spontaneously oxid...

Effective DNA repair enables cancer cells to survive DNA damage induced by chemotherapeutic or radiotherapeutic treatments. Therefore, inhibiting DNA repair pathways is a promising therapeutic strategy for increasing the efficacy of such treatments....

The objective of the work presented in this paper is to overcome several major shortcomings of the recently introduced 3D composites (3DCs) and their fiber–metal-laminate renditions (3DFMLs). A new class of lightweight, stiff, and resilient thr...

(1) Background: To support the energy transition in Europe, the EU has launched multiple initiatives. Supporting the “Green Deal” is the New European Bauhaus (NEB). District heating and cooling (DHC) is an important part of a decarbonized...

Stroke is a leading threat to human life. Metabolic dysfunction of glucose may play a key role in stroke pathophysiology. Pharmacological hypothermia (PH) is a potential neuroprotective strategy for stroke, in which the temperature is decreased safel...

De novo sterol synthesis is a critical homeostatic mechanism in the brain that begins during early embryonic development and continues throughout life. Multiple medications have sterol-biosynthesis-inhibiting side effects, with potentially detrimenta...

There is a large potential to integrate substantial shares of renewable energy and waste heat sources in district heating and/or cooling networks (DHC), reducing dependency of DHC on fossil fuels and ultimately leading to a more efficient and sustain...

Fifth-generation district heating and cooling (5th DHC) systems offer promising approaches to decarbonizing space heating, cooling and domestic hot water supply. By using these systems, clustered buildings combined with industrial waste heat can achi...

This study assessed the prevalence of orthodontic treatment needs and oral health-related quality of life (OHRQoL) in 12–18-year-old adolescents and explored the association between OHRQoL and treatment needs, gender, education level and family...

Using data from the German Hepatitis C-Registry (Deutsche Hepatitis C-Register, DHC-R), we report the real-world safety and effectiveness of glecaprevir/pibrentasvir (GLE/PIB) treatment and its impact on patient-reported outcomes (PROs) in underserve...

Chronic hepatitis C can be treated very effectively with direct-acting antivirals (DAA) with only minor side effects compared to an interferon-containing treatment regimen. The significance of metabolic comorbidities after HCV cure is not well define...

Dehydrocorydaline (DHC), a quaternary alkaloid from Corydalis yanhusuo, has been demonstrated to be the active constituent in the treatment of coronary heart disease. In this study, a high-performance liquid chromatography–electrospray ionization–tri...

Copper–zirconia catalysts find many applications in different reactions owing to their unique surface properties and relatively easy manufacture. The so-called methanol economy, which includes the CO2 and CO valorization and the hydrogen production,...

Dynamic simulation of district heating and cooling networks has an increased importance in the transition towards renewable energy sources and lower temperature district heating grids, as both temporal and spatial behavior need to be considered. Even...

Capsaicinoids are a unique chemical species resulting from a particular biosynthesis pathway of hot chilies (Capsicum spp.) that gives rise to 22 analogous compounds, all of which are TRPV1 agonists and, therefore, responsible for the pungency of Cap...

Considering the resistance of weeds to different herbicides with different mechanisms of action, the search for new, more selective compounds with low toxicity to other species in nature has been very important for the development of agriculture. Bec...

From September 8th to 12th, 2024, the 19th SDEWES Conference on Sustainable Development of Energy, Water, and Environment Systems was successfully held in Rome. This event drew 700 researchers, scientists, and practitioners from 62 nations across six...

The ontogenetic variation of total and individual capsaicinoids (nordihydrocapsaicin (n-DHC), capsaicin (C), dihydrocapsaicin (DHC), homocapsaicin (h-C) and homodihydrocapsaicin (h-DHC)) present in Malagueta pepper (Capsicum frutescens) during fruit...

This study explored short- and mid-term functional outcomes in patients undergoing decompressive hemicraniectomy (DHC) due to space-occupying cerebral infarction and asked whether there is a potentially harmful effect of a priorly performed endovascu...

7α,25-dihydroxycholesterol (7α,25-DHC) is an oxysterol synthesized from 25-hydroxycholesterol by cytochrome P450 family 7 subfamily B member 1 (CYP7B1) and is a monooxygenase (oxysterol-7α-hydroxylase) expressed under inflammatory c...

The paper presents the results of in situ studies of marine particles of different nature using a submersible digital holographic camera (DHC) during the Arctic expedition. It also describes the features, performance specifications, and possibilities...

Citrinin (CIT) is a nephrotoxic mycotoxin produced by Aspergillus, Penicillium, and Monascus genera. It appears as a contaminant in grains, fruits, and spices. After oral exposure to CIT, its major urinary metabolite, dihydrocitrinone (DHC) is formed...

Dihydrocapsaicin (DHC), a prominent capsaicinoid derived from red chili peppers, has shown cytotoxic effects against various cancer cell types. However, its role in modulating cytokine-induced survival and apoptotic signaling in cancer cells remains...

Excessive release of glutamate induces excitotoxicity and causes neuronal damage in several neurodegenerative diseases. Natural products have emerged as potential neuroprotective agents for preventing and treating neurological disorders. Dehydrocoryd...

Nowadays conventional district heating and cooling (DHC) systems face the challenge of reducing fossil fuel dependency while maintaining profitability. To address these issues, this study examines the possibility of retrofitting DHC systems with refu...

Background: The Index of Orthodontic Treatment Need (IOTN) is widely used to assess the need for orthodontic treatment. IOTN consists of the Dental Health Component (DHC) and the Aesthetic Component (AC), evaluating malocclusion morphologically and a...

5,8-Dihydroxycoumarin (5,8-DHC) was isolated from aerial parts of sweet grass (Hierochloë odorata L.) and screened for antioxidant and genotoxic activities. A clear linear dependency of radical scavenging capacity in DPPH• and ABTS•+ assays was deter...

A rapid, sensitive and selective liquid chromatography/tandem mass spectrometry method (LC-MS/MS) was developed and validated for determination of dehydrocorydaline (DHC) in rat plasma using nitidine chloride as an internal standard. The analytes wer...

This study investigated the nutritional composition, antinutritional factors, oxidative stability, microbiological safety, and sensory characteristics of hempseed cake (HC) derived from Cannabis sativa L. cv. ‘Henola’. The effects of dehu...

Dihydrochalcones (DHCs) constitute a specific class of flavonoids widely known for their various health-related advantages. Melatonin (MLT) has received attention worldwide as a master regulator in plants, but its roles in DHC accumulation remain unc...

Osteoarthritis (OA) causes severe degeneration of the meniscus and cartilage layer in the knee and endangers joint integrity and function. In this study, we utilized tumor necrosis factor α (TNFα) to establish in vitro OA models and analy...

Neutral-temperature district heating and cooling (NT-DHC) is a recent concept in the district heating sector. The current literature does not directly address the ability to create comprehensive master plans for NT-DHC systems and reliably model thei...

The present study assesses the validity and reproducibility of two occlusal indices for epidemiological studies—the Dental Aesthetic Index (DAI) and the Dental Health Component of the Index of Orthodontic Treatment Need (DHC-IOTN) for the identificat...

Smith-Lemli-Opitz syndrome (SLOS) is a severe monogenic disorder resulting in low cholesterol and high 7-dehydrocholesterol (7-DHC) levels. 7-DHC-derived oxysterols likely contribute to disease pathophysiology, and thus antioxidant treatment might be...

The paper presents an underwater holographic sensor to study marine particles—a miniDHC digital holographic camera, which may be used as part of a hydrobiological probe for accompanying (background) measurements. The results of field measurements of...

Daylily (Hemerocallis citrina Baroni) is an edible plant widely distributed worldwide, especially in Asia. It has traditionally been considered a potential anti-constipation vegetable. This study aimed to investigate the anti-constipation effects of...

A hydronic pavement system (HPS) is an alternative method to clear snow and ice, which avoids the use of salt, sand, and fossil fuel in conventional snow clearance, and minimizes the risk of accidents. The aim is to analyze the performance of differe...

Subacromial impingement syndrome (SIS) is one of the most common causes of shoulder pain in adults and is caused by muscle imbalance around the shoulder joint, which is referred to as secondary SIS. Centralization of the glenohumeral joint (CGH), one...

The emergence of antimicrobial resistance and rapid acclimation allows Vibrio vulnificus to rapidly propagate in the host. This problematic pathological scenario can be circumvented by employing an antivirulence strategy, treating Vibrio infections w...

Many researchers are devoted to improving the prediction accuracy of daily load profiles, so as to optimize day-ahead operation strategies to achieve the most efficient operation of district heating and cooling (DHC) systems; however, studies on load...

Saline stress impairs germination and initial plant growth. However, discontinuous hydration cycles induce osmotic tolerance in seeds and can improve the response of maize seeds to saline stress. The objective of this study was to evaluate the action...

Pilotis structures consisting of upper concrete bearing-walls and a soft first story have been well used in residential and office buildings in urban areas to primarily accommodate parking lots. In this research, drift-hardening concrete (DHC) column...

District heating and cooling (DHC) systems play an important role under the new European Union (EU) energy transition strategy. Thermal energy networks are helping to stimulate the development of alternative technologies based on a broad range of ren...

The cesarean section (CS) on maternal request increased sharply in China, bringing pressure to medical resources and national insurance. We assessed the use of clinical pathways (CPWs) for CS compared with conventional medical care by outcomes of len...

Vitamin D3 synthesis in human skin is initiated by solar ultraviolet radiation (UVR) exposure of precursor 7-dehydrocholesterol (7DHC), but influence of age on the early stage of vitamin D3 metabolism is uncertain. We performed a prospective standard...

Patients after orthopic liver transplantation (OLT) are at risk of developing graft dysfunction. Sphingolipids (SL’s) have been identified to play a pivotal role in the regulation of hepatocellular apoptosis, inflammation and immunity. We aimed to in...

20(S)-Hydroxyvitamin D3 (20(OH)D3) is an endogenous metabolite produced by the action of CYP11A1 on the side chain of vitamin D3 (D3). 20(OH)D3 can be further hydroxylated by CYP11A1, CYP27A1, CYP24A1 and/or CYP27B1 to several hydroxyderivatives. CYP...