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  • Review
  • Open Access
171 Citations
112,191 Views
34 Pages

Ashwagandha (Withania somnifera)—Current Research on the Health-Promoting Activities: A Narrative Review

  • Paulina Mikulska,
  • Marta Malinowska,
  • Miłosz Ignacyk,
  • Paweł Szustowski,
  • Joanna Nowak,
  • Karolina Pesta,
  • Monika Szeląg,
  • Damian Szklanny,
  • Eliza Judasz and
  • Gabriela Kaczmarek
  • + 4 authors

In recent years, there has been a significant surge in reports on the health-promoting benefits of winter cherry (Withania somnifera), also known as Ashwagandha. Its current research covers many aspects of human health, including neuroprotective, sed...

  • Review
  • Open Access
585 Citations
76,196 Views
46 Pages

Artificial Intelligence in Pharmaceutical Technology and Drug Delivery Design

  • Lalitkumar K. Vora,
  • Amol D. Gholap,
  • Keshava Jetha,
  • Raghu Raj Singh Thakur,
  • Hetvi K. Solanki and
  • Vivek P. Chavda

Artificial intelligence (AI) has emerged as a powerful tool that harnesses anthropomorphic knowledge and provides expedited solutions to complex challenges. Remarkable advancements in AI technology and machine learning present a transformative opport...

  • Review
  • Open Access
149 Citations
39,829 Views
27 Pages

Artificial Intelligence (AI) Applications in Drug Discovery and Drug Delivery: Revolutionizing Personalized Medicine

  • Dolores R. Serrano,
  • Francis C. Luciano,
  • Brayan J. Anaya,
  • Baris Ongoren,
  • Aytug Kara,
  • Gracia Molina,
  • Bianca I. Ramirez,
  • Sergio A. Sánchez-Guirales,
  • Jesus A. Simon and
  • Greta Tomietto
  • + 5 authors

Artificial intelligence (AI) encompasses a broad spectrum of techniques that have been utilized by pharmaceutical companies for decades, including machine learning, deep learning, and other advanced computational methods. These innovations have unloc...

  • Review
  • Open Access
4 Citations
35,616 Views
16 Pages

The mRNA- and DNA-based “genetic” COVID-19 vaccines can induce a broad range of adverse events (AEs), with statistics showing significant variation depending on the timing and data analysis methods used. Focusing only on lipid nanoparticl...

  • Review
  • Open Access
171 Citations
29,620 Views
39 Pages

Advancing Precision Medicine: A Review of Innovative In Silico Approaches for Drug Development, Clinical Pharmacology and Personalized Healthcare

  • Lara Marques,
  • Bárbara Costa,
  • Mariana Pereira,
  • Abigail Silva,
  • Joana Santos,
  • Leonor Saldanha,
  • Isabel Silva,
  • Paulo Magalhães,
  • Stephan Schmidt and
  • Nuno Vale

The landscape of medical treatments is undergoing a transformative shift. Precision medicine has ushered in a revolutionary era in healthcare by individualizing diagnostics and treatments according to each patient’s uniquely evolving health sta...

  • Review
  • Open Access
93 Citations
29,468 Views
24 Pages

Recent Advancement in mRNA Vaccine Development and Applications

  • Nojoud Al Fayez,
  • Majed S. Nassar,
  • Abdullah A. Alshehri,
  • Meshal K. Alnefaie,
  • Fahad A. Almughem,
  • Bayan Y. Alshehri,
  • Abdullah O. Alawad and
  • Essam A. Tawfik

Messenger RNA (mRNA) vaccine development for preventive and therapeutic applications has evolved rapidly over the last decade. The mRVNA vaccine has proven therapeutic efficacy in various applications, including infectious disease, immunotherapy, gen...

  • Review
  • Open Access
135 Citations
27,576 Views
22 Pages

Nanotechnology in Cancer Diagnosis and Treatment

  • Noor Alrushaid,
  • Firdos Alam Khan,
  • Ebtesam Abdullah Al-Suhaimi and
  • Abdelhamid Elaissari

Traditional cancer diagnosis has been aided by the application of nanoparticles (NPs), which have made the process easier and faster. NPs possess exceptional properties such as a larger surface area, higher volume proportion, and better targeting cap...

  • Review
  • Open Access
146 Citations
25,820 Views
52 Pages

A Guide to In Silico Drug Design

  • Yiqun Chang,
  • Bryson A. Hawkins,
  • Jonathan J. Du,
  • Paul W. Groundwater,
  • David E. Hibbs and
  • Felcia Lai

The drug discovery process is a rocky path that is full of challenges, with the result that very few candidates progress from hit compound to a commercially available product, often due to factors, such as poor binding affinity, off-target effects, o...

  • Review
  • Open Access
194 Citations
23,694 Views
36 Pages

A biomarker is any measurable biological moiety that can be assessed and measured as a potential index of either normal or abnormal pathophysiology or pharmacological responses to some treatment regimen. Every tissue in the body has a distinct biomol...

  • Review
  • Open Access
273 Citations
23,639 Views
34 Pages

Solid Lipid Nanoparticles vs. Nanostructured Lipid Carriers: A Comparative Review

  • Cláudia Viegas,
  • Ana B. Patrício,
  • João M. Prata,
  • Akhtar Nadhman,
  • Pavan Kumar Chintamaneni and
  • Pedro Fonte

Solid–lipid nanoparticles and nanostructured lipid carriers are delivery systems for the delivery of drugs and other bioactives used in diagnosis, therapy, and treatment procedures. These nanocarriers may enhance the solubility and permeability...

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Pharmaceutics - ISSN 1999-4923