Special Issues

Pharmaceutics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Pathophysiological Influences on Pharmacokinetics and Pharmacodynamics
edited by Geraldo Duarte, Fernanda de Lima Moreira and Jhohann Richard de Lima Benzi
submission deadline 20 Nov 2025 | 3 articles | Viewed by 8645 | Submission Open
Keywords: drug– disease interactions; pharmacokinetics; pharmacodynamics; pharmacotherapy
(This special issue belongs to the Section Pharmacokinetics and Pharmacodynamics)
Novel Drug Delivery Systems for the Treatment of Skin Disorders submission deadline 20 Nov 2025 | 4 articles | Viewed by 6723 | Submission Open
Keywords: drug delivery; nanoparticles; vesicular systems; 3D-printed drugs; topical dosage form; skin disorder; penetration
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Nanotechnology and RNA-Based Technologies Applied to Prophylaxis and Advanced Therapies
edited by and Vinicius Pinto Costa Rocha
submission deadline 20 Nov 2025 | 1 articles | Viewed by 4606 | Submission Open
Keywords: RNA-technologies; nanotechnology; messenger RNA (mRNA); interference RNA (RNAi); vaccines; treatment
(This special issue belongs to the Section Gene and Cell Therapy)
Long Acting Drug Delivery Formulations
edited by Thierry Vandamme
submission deadline 20 Nov 2025 | 1 articles | Viewed by 4585 | Submission Open
Keywords: improvement in patient adherence; steady state; drug bioavailability; reduced side effect; targeted delivery; long acting; sustained release; prolonged release; pulse release; compliance
(This special issue belongs to the Section Physical Pharmacy and Formulation)
Biomaterials: Pharmaceutical Applications
edited by
submission deadline 20 Nov 2025 | 3 articles | Viewed by 3555 | Submission Open
Keywords: natural biomaterials; synthetic biomaterials; drug delivery systems; tissue engineering; disease diagnosis; wound healing
(This special issue belongs to the Section Biopharmaceutics)
“The Power of Light” in Biomedical and Pharmaceutics: New Approaches for Photodynamic Purposes submission deadline 20 Nov 2025 | 1 articles | Viewed by 962 | Submission Open
Keywords: light; photosensitizers; photochemistry; photobiology; photodynamic therapy
(This special issue belongs to the Section Drug Targeting and Design)
Antibody–Drug Conjugates Therapeutics submission deadline 20 Nov 2025 | 1 articles | Viewed by 724 | Submission Open
Keywords: antibody– drug conjugate; drug delivery; antibody; payload; linker; protein conjugation
(This special issue belongs to the Section Biologics and Biosimilars)
Recent Advances in Drug Formulation for Antiviral Therapy
edited by Chiara Medaglia
submission deadline 20 Nov 2025 | Viewed by 436 | Submission Open
Keywords: antiviral drugs development; infection; host-pathogen interactions; functional genomics
(This special issue belongs to the Section Drug Targeting and Design)
Drug Product Performance: Bioavailability, Relative Bioavailability and Bioequivalence, 2nd Edition
edited by
submission deadline 30 Nov 2025 | 10 articles | Viewed by 23144 | Submission Open
Keywords: bioavailability; relative bioavailability; bioequivalence; biowaivers; statistical issues; regulatory issues; in vitro– in vivo correlations; physiologically-based biopharmaceutical models; physiologically-based pharmacokinetic models; qualification of models; population pharmacokinetic models; biopharmaceutical classification system; in vitro dissolution; dissolution metrics; predictive dissolution; clinical trial simulations; clinical trial optimization; healthy subjects in BA/BE trials; patients in BA/BE trials; pharmacokinetic parameters for BA/BE assessment; narrow therapeutic index drugs; highly variable drug products; immediate-release formulations; modified-release formulations; multiphasic drug products; extravascular routes of administration
(This special issue belongs to the Section Biopharmaceutics)
Advances in Drug Delivery Systems for the Treatment of Chronic Wound Healing
edited by Carolina Martinez and María Jimena Prieto
submission deadline 30 Nov 2025 | 10 articles | Viewed by 18085 | Submission Open
Keywords: wound healing; chronic diseases; wound repair and regeneration; drug delivery; topical formulations; biomaterial; nanotechnology; wound dressing; scar
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Inorganic Nanomaterials for the Development of Drug Delivery and Biomedical Applications
edited by
submission deadline 30 Nov 2025 | 3 articles | Viewed by 8517 | Submission Open
Keywords: inorganic nanoparticles; drug delivery; disease diagnosis; disease treatment; nano-biosensor; cancer theranostics; cancer imaging
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Advancements and Innovations in Antibody Drug Conjugates
edited by , Shivaji Edupuganti and Ebaston Thankarajan
submission deadline 30 Nov 2025 | 5 articles | Viewed by 8443 | Submission Open
Keywords: antibody– drug conjugates; monoclonal antibodies; targeted therapies; linker technologies; site-specific conjugation; bioimaging; pharmacokinetics; therapeutic index; next-generation ADCs; drug resistance; bispecific antibodies; combination therapies; off-target toxicity; efficacy and safety; tumor-specific antigens
(This special issue belongs to the Section Drug Targeting and Design)
Hybrid Nanoparticles for Cancer Therapy
edited by Jacy Gameiro
submission deadline 30 Nov 2025 | 5 articles | Viewed by 7300 | Submission Open
Keywords: hybrid nanoparticles; cancer therapy; targeted drug delivery; nanomedicine; tumor microenvironment; gene therapy; immunotherapy; diagnostics; nanomaterials
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Naturally Derived Materials-Based Drug Delivery Systems and Their Biomedical Applications
edited by and
submission deadline 30 Nov 2025 | 3 articles | Viewed by 6673 | Submission Open
Keywords: naturally derived material; drug delivery systems; tissue engineering; regenerative medicine
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Advances in Granulation Processes in Pharmaceutical Formulation Systems
edited by Krunoslav Žižek and
submission deadline 30 Nov 2025 | 3 articles | Viewed by 5331 | Submission Open
Keywords: granulation; drug formulation; tableting; process modelling; process optimization; scale-up
(This special issue belongs to the Section Pharmaceutical Technology, Manufacturing and Devices)
Microneedles for Drug and Vaccine Delivery
edited by
submission deadline 30 Nov 2025 | 2 articles | Viewed by 4153 | Submission Open
Keywords: physical enhancement technologies; fabrication; characterization; applications; drug delivery; cosmetic applications; diagnostic; vaccination
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Brain Tumors Treatment: Current and Future Challenges from Drug Formulations to Delivery Methods
edited by , Sara Badodi and
submission deadline 30 Nov 2025 | 1 articles | Viewed by 3459 | Submission Open
Keywords: blood– brain barrier pathophysiology in different tumors; pediatric brain tumors; adult brain tumors; considerations for adult vs. pediatric drug delivery development; nanocarriers and nanoparticles; focused ultrasound; convection enhanced delivery; intranasal delivery; intra-arterial delivery; combination strategies
(This special issue belongs to the Section Drug Targeting and Design)
Natural Compounds in Drug Delivery Systems submission deadline 30 Nov 2025 | 2 articles | Viewed by 3111 | Submission Open
Keywords: natural products; extraction techniques; phytochemical analyses; natural compounds; biological active compounds; new formulations; encapsulated technics; biotechnology; drug delivery systems; bioavailability; pharmacy
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Advances in Solid and Semi-Solid Dosage Form Design for Enhanced Biopharmaceutical Performance submission deadline 30 Nov 2025 | 2 articles | Viewed by 2761 | Submission Open
Keywords: solid dosage forms (tablets; capsules; pellets); novel formulation strategies; bioavailability enhancement; amorphous solid dispersions; lipid-based formulations; pharmaceutical cocrystals; excipient functionality and drug release; 3D printing in pharmaceuticals; hot melt extrusion (HME); spray drying in drug formulation; co-processing techniques; controlled and sustained drug release; targeted drug delivery systems; in vitro/in vivo correlation (IVIVC); quality-by-design (QbD) in pharmaceutics
(This special issue belongs to the Section Biopharmaceutics)
In Vitro and In Vivo Biopharmaceutics Assessment of Silica-Based Drug Delivery Systems: Characterization, Drug Release, and Biological Performance submission deadline 30 Nov 2025 | 2 articles | Viewed by 2584 | Submission Open
Keywords: drug delivery systems; mesoporous silica nanoparticles; biopharmaceutics evaluation; controlled drug release; drug release kinetics; in vivo performance; in vitro methodologies; pharmaceutical nanotechnology; stimuli-responsive systems; therapeutic efficacy
(This special issue belongs to the Section Biopharmaceutics)
Controlled Delivery of Cosmeceuticals Using Nanotechnology submission deadline 30 Nov 2025 | 1 articles | Viewed by 2406 | Submission Open
Keywords: cosmeceuticals; skin; targeting; cosmetics; nanotechnology; delivery; formulation
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Nanosystems for Advanced Diagnostics and Therapy submission deadline 30 Nov 2025 | 1 articles | Viewed by 2114 | Submission Open
Keywords: nanosystems; theranostics; nanomedicine; molecular imaging; targeted drug delivery; radiolabeled nanoparticles; image guided therapy; smart nanocarriers; nanoradiopharmaceuticals; nanotechnology in diagnostics
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Nanoemulsions for Nose-to-Brain Drug Delivery
edited by Clóvis Orlando Pereira Da Fonseca and
submission deadline 30 Nov 2025 | 1 articles | Viewed by 2087 | Submission Open
Keywords: nanoemulsion; intranasal; pharmacokinetics; nose-to-brain; neurology; olfactory; nanomedicine
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
In Silico Approaches of Drug–Target Interactions
edited by
submission deadline 30 Nov 2025 | 1 articles | Viewed by 2002 | Submission Open
Keywords: in silico drug discovery; drug– target interactions; virtual screening; molecular modeling; machine learning in drug design; ADME predictions
(This special issue belongs to the Section Drug Targeting and Design)
Advances in Vaccine Delivery and Vaccine Administration submission deadline 30 Nov 2025 | 1 articles | Viewed by 1965 | Submission Open
Keywords: vaccine delivery; vaccination; vaccine immunity; humoral immune response; cell-mediated immunity; infectious diseases; vaccine administration; novel routes of vaccination; nanoparticles
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Therapeutic Drug Monitoring as a Useful Tool in Therapy Improvement, 3rd Edition submission deadline 30 Nov 2025 | 2 articles | Viewed by 1752 | Submission Open
Keywords: drug– drug interactions; pharmacokinetics; therapeutic drug monitoring; machine learning
(This special issue belongs to the Section Clinical Pharmaceutics)
Alternative Animal Models for Nanoparticle-Based Drug Delivery: Efficacy and Toxicity Assessment submission deadline 30 Nov 2025 | 1 articles | Viewed by 1742 | Submission Open
Keywords: alternative animal models; nanoparticle drug delivery; nanomedicine; toxicity assessment; bioavailability; in vivo models; biodistribution studies; therapeutic efficacy; pharmaceutical testing
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Novel Therapeutic Agents and Innovative Delivery Systems Against Infectious Diseases
edited by Sara Consalvi
submission deadline 30 Nov 2025 | 1 articles | Viewed by 1709 | Submission Open
Keywords: medicinal chemistry; antibacterials; antivirals; antimicrobials; drug resistance; drug delivery; drug candidate; drug repurposing
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Innovative Drug Delivery Systems: From Nanotechnology to Smart Devices
edited by Mahdi Ghavami and
submission deadline 30 Nov 2025 | 1 articles | Viewed by 1644 | Submission Open
Keywords: smart nanoparticles; innovative drug delivery; ingestible devices; targeted delivery systems; controlled release; microfabrication techniques; nano and microtechnology; biocompatible materials; bioavailability
(This special issue belongs to the Section Pharmaceutical Technology, Manufacturing and Devices)
Innovations in Advanced Drug Delivery Systems: Overcoming Challenges for Personalized Medicine
edited by Hélcio Silva Dos Santos
submission deadline 30 Nov 2025 | 1 articles | Viewed by 1392 | Submission Open
Keywords: drug administration; polymers; structural characterization; nanoparticles; in silico studies; toxicity; bioavailability
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Advanced Drug Delivery Systems for Natural Products submission deadline 30 Nov 2025 | 1 articles | Viewed by 1311 | Submission Open
Keywords: natural products; advanced drug delivery systems; liposomes; niosomes; phytosomes; lipid nanoparticles; smart polymers; biodegradable nanoparticles; polymeric nanoparticles; drug carriers
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Recent Advances in Physiologically Based Biopharmaceutics Modeling
edited by Atsushi Kambayashi
submission deadline 30 Nov 2025 | 1 articles | Viewed by 1000 | Submission Open
Keywords: oral drug absorption; bioavailability; bioequivalence; modeling and simulation; physiologically based biopharmaceutics modeling
(This special issue belongs to the Section Pharmacokinetics and Pharmacodynamics)
Engineering and Characterisation of Novel Nanomedicine Formulations, 3rd Edition
edited by and Raquel Fernández García
submission deadline 30 Nov 2025 | 1 articles | Viewed by 679 | Submission Open
Keywords: nanoparticles; liposomes; solid lipid nanocapsules; drug targeting; cancer; infectious diseases; nanovaccines
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Carbon-Based Nanomaterials for Pharmaceutical Applications
edited by and Ivana Borišev
submission deadline 30 Nov 2025 | Viewed by 644 | Submission Open
Keywords: carbon-based nanomaterials; drug delivery; fullerenes; graphene; carbon nanotubes; nanodiamonds; carbon dots; biocompatibility; pharmaceutical applications
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Anti-Inflammatory Effects from Natural Bioactive Compounds—from Bench to Bedside, 3rd Edition
edited by
submission deadline 30 Nov 2025 | 1 articles | Viewed by 520 | Submission Open
Keywords: inflammation; bioproducts; isolated compounds; cytokines; macrophages; autoimmune diseases; in vivo assay; in vitro assay
(This special issue belongs to the Section Drug Targeting and Design)
Developing Drug Delivery Approaches for Both Phage Therapeutics and Phage-Based Vectors
edited by and Daniel De Vos
submission deadline 30 Nov 2025 | Viewed by 441 | Submission Open
Keywords: phage vector; drug delivery; phage therapy; phage technology
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Smart Drug Delivery Systems for Immunotherapeutic Agents submission deadline 30 Nov 2025 | Viewed by 372 | Submission Open
Keywords: immunotherapy; drug delivery systems; nanomedicine; targeted therapy; cancer immunotherapy; lipid nanoparticles; biomaterials; controlled rel ease; immunoengineering; translational medicine
(This special issue belongs to the Section Gene and Cell Therapy)
Metal Nanoparticles in Therapeutics: Pioneering Drug Delivery Systems and Tissue Engineering submission deadline 30 Nov 2025 | Viewed by 285 | Submission Open
Keywords: metal nanoparticles; drug delivery systems; tissue engineering; cancer therapy; nanomedicine
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Biomaterials for Skin Drug Delivery
edited by
submission deadline 30 Nov 2025 | Viewed by 281 | Submission Open
Keywords: skin drug delivery; transdermal delivery; topical delivery; skin permeation; biomaterials; hydrogels; microneedles; nanocarriers; bioresponsive materials
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Advancing Block Co-Polymer Nanomedicines: Innovations in Effective Drug Delivery submission deadline 30 Nov 2025 | Viewed by 271 | Submission Open
Keywords: pluronic-based nanomedicines and hydrogels; gene delivery; advanced drug delivery systems; radiotherapy and photodynamic therapy; combination therapy; polymeric nanomedicines; immunotherapy; nanogels; small-molecule delivery systems; block co-polymers nanomedicines
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
A New Generation of Metal Anticancer Drugs
edited by
submission deadline 30 Nov 2025 | Viewed by 239 | Submission Open
Keywords: metal-based drugs; cytotoxicity; cancer; nanoparticles; drug delivery
(This special issue belongs to the Section Physical Pharmacy and Formulation)
Biocompatible Polymer-Based Nanocarriers and Nanocomposites as Drug Delivery Systems
edited by
submission deadline 30 Nov 2025 | Viewed by 208 | Submission Open
Keywords: biocompatible nanocomposites; polymer-based nanocomposites; drug delivery; controlled-release systems; nanocarriers; nanomedicine; nanocomposite toxicity; vaccines; gene delivery; cancer therapy; neurodegenerative diseases
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Formulation of Lipid-Based Nanocapsules: Drug Release, Permeability, Biocompatibility, and Stability Studies
edited by and Carolina Arrúa
submission deadline 30 Nov 2025 | Viewed by 207 | Submission Open
Keywords: drug delivery; lipid nanocapsules; permeability; biocompatibility; therapeutic efficacy
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Next-Generation Non-Viral Vectors for Gene Therapy and DNA Vaccination
edited by
submission deadline 30 Nov 2025 | Viewed by 204 | Submission Open
Keywords: non-viral vectors; gene therapy; DNA vectors; plasmid vectors; mRNA vectors; lipid nanoparticles (LNPs); cell-free DNA synthesis; gene electrotransfer; targeted gene delivery; non-viral vector manufacturing; clinical translation of gene therapies
(This special issue belongs to the Section Gene and Cell Therapy)
The Preparation of an Exosome/Liposomal Nano-Drug Delivery System and Its Application in the Treatment of Inflammatory Bowel Disease
edited by and
submission deadline 30 Nov 2025 | Viewed by 171 | Submission Open
Keywords: exosomes; liposomes; nano-drug delivery systems; inflammatory bowel disease (IBD); targeted therapy; mucosal drug delivery; drug encapsulation; immunomodulation; nanomedicine; extracellular vesicles; personalized medicine
(This special issue belongs to the Section Drug Delivery and Controlled Release)
The Exciting Opportunities That Radiopharmaceuticals Have to Offer: Nuclear Medicine Imaging, Therapy and Drug Delivery Systems
edited by Yanli Wang and
submission deadline 30 Nov 2025 | Viewed by 163 | Submission Open
Keywords: PET imaging; theranostics; molecular imaging probes; radionuclide therapy; neuroimaging; radiochemistry
(This special issue belongs to the Section Drug Targeting and Design)
Model-Based Formulation Strategies for Controlled Release of Active Ingredients
edited by , Patrick D. Sinko and
submission deadline 30 Nov 2025 | Viewed by 160 | Submission Open
Keywords: in vitro and in vivo correlation; simultaneous dissolution– absorption evaluation; controlled release; sustained release; drug delivery systems; nanoparticles; micelles; liposomes; nanomaterials; amorphous solid dispersions; molecular dynamics simulations; computational fluid dynamics; computationally designed proteins; computationally designed peptides; pharmacokinetic model; pharmacometric model; 3D printing (personalized medicines/materials development/printing technologies)
(This special issue belongs to the Section Physical Pharmacy and Formulation)
Smart Radiotherapy Biomaterials for Cancer Therapy and Imaging submission deadline 10 Dec 2025 | 1 articles | Viewed by 1261 | Submission Open
Keywords: multifunctional biomaterials; theranostic biomaterials; smart drug delivery systems; nanobiomaterials; cancer radiotherapy; polymer-based biomaterials nanocarriers customizable biomaterials for cancer therapy and imaging smart nanomaterials
(This special issue belongs to the Section Drug Targeting and Design)
PLGA Implants for Controlled Drug Release
edited by Emma Portnoy
submission deadline 10 Dec 2025 | 1 articles | Viewed by 554 | Submission Open
Keywords: nanoparticles; drug delivery; liposomes; lipid nanoparticles; PLGA nanoparticles; PLA nanoparticles
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Chitosan in Modern Pharmacotherapy: From Drug Encapsulation to Targeted Delivery Systems
edited by Robertas Lazauskas, Dalia Adukauskienė, and Inga Staneviciene
submission deadline 10 Dec 2025 | Viewed by 159 | Submission Open
Keywords: chitosan-based nanoparticles; oxidative stress; targeted drug delivery; biopharmaceutical applications; clinical translation
(This special issue belongs to the Section Drug Delivery and Controlled Release)
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