Special Issues

Pharmaceutics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advanced Pediatric Drug Formulation Strategies
edited by and Okhee Yoo
submission deadline 10 Aug 2025 | 5 articles | Viewed by 12631 | Submission Open
Keywords: paediatric/pediatric; taste masking; 3D printing; nanotechnology; PK-informed personalized medicines; non-oral pediatric formulations; AI-directed pediatric formulations
(This special issue belongs to the Section Physical Pharmacy and Formulation)
Microarray Patches for Transdermal Drug Delivery
edited by and Aaron Hutton
submission deadline 20 Aug 2025 | 8 articles | Viewed by 24830 | Submission Open
Keywords: microarray patches; manufacturing methods; biotherapeutic agents; long-acting transdermal drug delivery; end-user microarray patch designs
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Drug Formulation and Controlled Release Systems for the Gastrointestinal Tract
edited by Borislav S. Tzankov, and Teodora Popova
submission deadline 20 Aug 2025 | 3 articles | Viewed by 6889 | Submission Open
Keywords: gastrointestinal diseases; gastrointestinal tract; gastrointestinal cancer; colorectal cancer; rectal cancer; nanomedicine; drug formulation; drug delivery systems; nanocarriers; targeted drug delivery; nanotechnology; pharmaceutical science; nano-bioengineering
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Application of Nanomedicine in Metabolic and Chronic Diseases
edited by Mehrnaz Abbasi
submission deadline 20 Aug 2025 | 2 articles | Viewed by 4781 | Submission Open
Keywords: nanomedicine; metabolic diseases; chronic diseases; drug delivery; nanoscale materials; targeted therapy; controlled release
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Advances in Inhaled Formulations for Pulmonary Drug Delivery
edited by and
submission deadline 20 Aug 2025 | 1 articles | Viewed by 2131 | Submission Open
Keywords: inhaled biologic; inhaled combination therapy; inhaled gene therapy; inhaled nanoparticles; novel inhalable nano-formulation; stability; solubility; smart inhalers; three-dimensional printing
(This special issue belongs to the Section Physical Pharmacy and Formulation)
Small-Molecule Inhibitors for Novel Therapeutics
edited by and Simone Giovannuzzi
submission deadline 20 Aug 2025 | 1 articles | Viewed by 2091 | Submission Open
Keywords: small molecules; enzyme inhibition/activation; protein modulation; novel therapeutics; high-throughput screening; target proteins; drug delivery
(This special issue belongs to the Section Drug Targeting and Design)
The Role of Freeze-Drying in Biopharmaceutical Manufacturing: Stability and Efficacy submission deadline 20 Aug 2025 | Viewed by 467 | Submission Open
Keywords: freeze-drying; biopharmaceuticals; process scale-up; technology transfer; and validation; process analytical technology; analytical techniques for FD products
(This special issue belongs to the Section Pharmaceutical Technology, Manufacturing and Devices)
Pharmaceutical Nanotechnology for the Treatment of Leishmaniasis and Chagas Diseases
edited by , Gustavo Henrique Bianco de Souza and Janaína Brandão Seibert
submission deadline 20 Aug 2025 | Viewed by 378 | Submission Open
Keywords: nanoformulation; leishmaniasis; chagas disease; nanotechnology; drug toxicity; bioavailability; nanomedicine; dosage form
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Targeted Delivery of Genes submission deadline 20 Aug 2025 | Viewed by 311 | Submission Open
Keywords: targeting; disease targeting; organ targeting; tissue or cell targeting; oligonucleotides; mRNA; CRISPR; nanoparticle; lipid nanoparticle (LNP); delivery system; siRNA; microRNA; antisense RNA; plasmid DNA; delivery vector
(This special issue belongs to the Section Gene and Cell Therapy)
Nanomaterials for Immunotherapeutic Improvement in Cancer Chemotherapy submission deadline 20 Aug 2025 | Viewed by 246 | Submission Open
Keywords: cancer immunotherapy; chemotherapeutics; nanomaterials; drug delivery and targeting; clinical translation
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Advances in Nanomaterials for Wound Healing
edited by and
submission deadline 20 Aug 2025 | Viewed by 238 | Submission Open
Keywords: controlled drug release; nanoparticles and antibacterial properties; nanomedicine; wound dressing
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Innovative 3D Printing Techniques for Personalized Anti-Cancer Therapy
edited by Kejing Shi and
submission deadline 20 Aug 2025 | Viewed by 233 | Submission Open
Keywords: 3D printing; personalized medicine; anti-cancer therapy; bioprinting; tumor treatment; additive manufacturing; drug delivery
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Bio-Based Hydrogels: Sustainable and Efficient Drug Delivery Solutions
edited by Vesna V. Panić, Rada Pjanović and
submission deadline 20 Aug 2025 | 1 articles | Viewed by 180 | Submission Open
Keywords: bio-based hydrogel; drug delivery system; hydrogel composites; controlled delivery; targeted delivery; drug loading; drug release kinetics; degradation; administration routes; oral delivery; transdermal delivery; in vitro and in vivo analyses
(This special issue belongs to the Section Drug Delivery and Controlled Release)
State of the Art of Drug–Membrane Interactions: Advancing Drug Delivery Systems and Therapeutic Efficacy submission deadline 20 Aug 2025 | Viewed by 131 | Submission Open
Keywords: drug– lipid interaction; molecular interactions; membrane-active drugs; drug side effects; drug delivery
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Targeted Biomolecule Delivery via Extracellular Vesicles in Inter-Organ Cross-Talk and Neuroinflammation submission deadline 20 Aug 2025 | Viewed by 89 | Submission Open
Keywords: extracellular vesicles; targeted biomolecules delivery; brain-gut axis; brain-muscle communication; periphery-brain crosstalk; bilateral communication; central nervous system disorders; neuroinflammation
(This special issue belongs to the Section Biologics and Biosimilars)
Next-Generation Antibody-Drug Conjugates (ADCs)
edited by Yasuaki Anami
submission deadline 30 Aug 2025 | 2 articles | Viewed by 9444 | Submission Open
Keywords: antibody– drug conjugate; bioconjugation; vancer therapy; targeted therapy; bystander effect
(This special issue belongs to the Section Drug Targeting and Design)
State of the Art of Membrane Active Peptides, 2nd Edition submission deadline 30 Aug 2025 | 3 articles | Viewed by 5536 | Submission Open
Keywords: cell-penetrating peptides; antimicrobial peptides; homing peptides; drug delivery system; cellular internalization; nanoparticles; cellular targeting; therapeutics; diagnostics
(This special issue belongs to the Section Drug Targeting and Design)
Advances in Colloidal Drug Delivery Systems
edited by
submission deadline 30 Aug 2025 | 1 articles | Viewed by 1408 | Submission Open
Keywords: colloidal drug delivery; liposomes; nanoparticles; micelles; solubility enhancement; bioavailability; targeted delivery; controlled release
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Emerging Trends and Advancements in Anticancer Photodynamic Therapy: Innovative Delivery Systems, Translational Insights, and Breakthroughs
edited by Anine Crous and
submission deadline 30 Aug 2025 | Viewed by 146 | Submission Open
Keywords: photodynamic therapy (PDT); anticancer therapy; photosensitizers; nanotechnology; immune modulation; imaging-guided therapy; combination therapies; preclinical studies; clinical translation; light-based therapy
(This special issue belongs to the Section Clinical Pharmaceutics)
Advanced Polymeric Materials as Therapeutic Agents
edited by , William Facchinatto and Regiane Godoy de Lima
submission deadline 31 Aug 2025 | 2 articles | Viewed by 4234 | Submission Open
Keywords: biomaterial; biopolymers; photodynamic inactivation; nanotechnology; drug delivery; polymer– drug conjugates; spectroscopic characterization; theragnostic; tissue engineering
(This special issue belongs to the Section Pharmaceutical Technology, Manufacturing and Devices)
Graphene and Graphene Family Nanomaterials for Biomedical Applications submission deadline 31 Aug 2025 | 2 articles | Viewed by 3672 | Submission Open
Keywords: graphene; graphene oxide; biomedical applications; cancer; regeneration; drug delivery; antimicrobial effect
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Pharmaceutical Solid Dosage Forms: Manufacturing, Design, Development, and Biomedical Applications
edited by
submission deadline 31 Aug 2025 | 5 articles | Viewed by 3667 | Submission Open
Keywords: pharmaceutical solid dosage forms; pharmaceutical manufacturing; hot-melt extrusion; formulation development; 3D printing; film coating; biomaterials; polymers; drug delivery systems
(This special issue belongs to the Section Physical Pharmacy and Formulation)
New Advances and Applications of Cryogels in Drug Delivery and Regenerative Medicine submission deadline 31 Aug 2025 | 2 articles | Viewed by 3415 | Submission Open
Keywords: cryogels; drug delivery; regenerative medicine; tissue engineering; controlled release; modeling and computation
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Drug Delivery for Natural Extract Applications
edited by , , Milica Radan and Jelena Mudrić
submission deadline 31 Aug 2025 | 2 articles | Viewed by 3350 | Submission Open
Keywords: natural-based extracts; natural-based products; bioactive compounds; optimization of extraction; green and conventional extraction methods; by-product; waste; unexploited; underutilized products; antioxidants; biological activities; mode of action; encapsulation; carriers and biopolymers; drug delivery system; therapeutics
(This special issue belongs to the Section Biopharmaceutics)
ROS-Mediated Nano Drug Delivery for Antitumor Therapy
edited by Yanjuan Huang and Xiaoyu Xu
submission deadline 31 Aug 2025 | 3 articles | Viewed by 3077 | Submission Open
Keywords: antitumor therapy; reactive oxygen species (ROS); ROS-mediated biomedical nanotechnology; ROS-responsive nano drug delivery; ROS-mediated immunotherapy; ROS-mediated combination therapy; oxidation therapy; photodynamic therapy (PDT); sonodynamic therapy (SDT); chemodynamic therapy (CDT); radiodynamic therapy (RDT); microdynamic therapy (MDT); electrodynamic therapy (EDT)
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Development and Evaluation of Inhalable Dry Powder Formulations, 2nd Edition submission deadline 31 Aug 2025 | 2 articles | Viewed by 3066 | Submission Open
Keywords: respiratory delivery; dry powder inhalation; particle engineering design; physicochemical characterization; aerosolization; lung delivery; nasal delivery
(This special issue belongs to the Section Physical Pharmacy and Formulation)
Nano-Based Delivery Systems for Topical Applications submission deadline 31 Aug 2025 | 2 articles | Viewed by 3024 | Submission Open
Keywords: nanoparticles; topical delivery; lipid-based nanoparticles; polymeric nanoparticles; psoriasis; drug delivery to nails; topical ocular diseases; skin cancers; nanoparticles in cosmetics
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Recent Advances in Cocrystal and Nano-Cocrystal Technologies for Pharmaceutical and Nutraceutical Applications
edited by Jiamei Chen
submission deadline 31 Aug 2025 | 2 articles | Viewed by 1700 | Submission Open
Keywords: crystal engineering; multicomponent crystals; cocrystal; nanococrystal; controllable synthesis; poorly soluble active ingredient; solubilization; bioavailability; pharmaceutical; nutraceutical; co-delivery; combination product
(This special issue belongs to the Section Physical Pharmacy and Formulation)
Electroporation-Mediated Drug and Gene Delivery submission deadline 31 Aug 2025 | 2 articles | Viewed by 1671 | Submission Open
Keywords: electroporation; drug delivery; gene electrotransfer; electrochemotherapy; pulsed electric field; gene delivery
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Nanoparticle-Based Drug Delivery Systems for the Treatment of Ocular Diseases
edited by Daniela Alejandra Quinteros
submission deadline 31 Aug 2025 | 1 articles | Viewed by 1551 | Submission Open
Keywords: anterior segment; posterior segment; drug delivery systems; nanotechnology; ocular diseases; ocular barriers
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Hormonal Medications: Clinical Approaches and Technological Advancements
edited by Roberto Pontarolo, and
submission deadline 31 Aug 2025 | 1 articles | Viewed by 1472 | Submission Open
Keywords: hormonal medications; drug monitoring; cancer; diabetes; drug delivery; hormone therapies; clinical studies
(This special issue belongs to the Section Clinical Pharmaceutics)
Pharmaceutical Applications of Vesicle and Nanocarrier Delivery Strategies
edited by Paul Meers, Patrick L. Ahl and Shaukat Ali
submission deadline 31 Aug 2025 | 1 articles | Viewed by 1391 | Submission Open
Keywords: nanoscale vesicles; outer membrane vesicles; delivery systems; liposome; delivery vehicle; nanocarrier; nanoparticle technologies; drug delivery
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Development and Optimization of Buccal Films Formulations
edited by and Krisztián Pamlényi
submission deadline 31 Aug 2025 | 1 articles | Viewed by 1081 | Submission Open
Keywords: buccal drug delivery; mucoadhesive; polymer films; buccal tablets; solid dosage forms; controlled drug release; fast dissolving formulations; permeability enhancement; pediatric formulations; geriatric formulations
(This special issue belongs to the Section Physical Pharmacy and Formulation)
Advancing Cancer Therapy: Magnetic Nanoparticles for Enhanced Targeted Drug Delivery submission deadline 31 Aug 2025 | 1 articles | Viewed by 989 | Submission Open
Keywords: cancer therapy; drug delivery; magnetic drug targeting; superparamagnetism; hyperthermia; magnetite; ferrite; iron oxide magnetic nanoparticles; superparamagnetic iron oxide nanoparticles; cytotoxicity; apoptosis; magnetic biosensors; magnetic imaging; theranostics
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Innovative Applications of Nanotechnology and Photothermal Therapy in Cancer Treatment and Drug Delivery submission deadline 31 Aug 2025 | 1 articles | Viewed by 945 | Submission Open
Keywords: photothermal therapy; drug delivery; chemotherapy; nanomaterials; local and systemic delivery; in situ delivery; nanoscale dosage forms; nanomedicine; pre-clinical studies; in vitro models; regulatory affairs
(This special issue belongs to the Section Clinical Pharmaceutics)
Applications of Nanotechnology in Veterinary Drug Delivery submission deadline 31 Aug 2025 | 2 articles | Viewed by 827 | Submission Open
Keywords: nanotechnology; veterinary medicine; drug delivery
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Nanocarriers in Cardiovascular Medicine: Current Applications and Future Perspectives
edited by and Francislaine Aparecida Dos Reis Lívero
submission deadline 31 Aug 2025 | 1 articles | Viewed by 647 | Submission Open
Keywords: drug delivery; biopharmaceutical; quality control; nanocarriers; nanoparticle; cardioprotection; hypertension; drug development; arteriosclerosis; thrombosis
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Nanotechnology in the Treatment of Neglected Parasitic Diseases submission deadline 31 Aug 2025 | 1 articles | Viewed by 618 | Submission Open
Keywords: neglected disease; nanotechnology; parasitic disease; modified release; sustained release; nanoparticles; liposomes; nanoemulsions
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Advanced Research on Amorphous Drugs
edited by
submission deadline 31 Aug 2025 | 1 articles | Viewed by 598 | Submission Open
Keywords: high-throughput screening; combinatorial chemistry; poorly water-soluble compounds; poor water solubility; bioavailability; innovative preparation methods; amorphous drug formulations; free energy; novel evaluation techniques; advanced predictive models; physical stability; mechanistic insights
(This special issue belongs to the Section Physical Pharmacy and Formulation)
Advancements in Tablet Formulation and Technological Innovations in Pharmaceutical Manufacturing submission deadline 31 Aug 2025 | Viewed by 439 | Submission Open
Keywords: tablets; capsules; granules; powders; oral solid dosage forms; OSDF; pharmaceutical technology; direct compression; granulation; pharmaceutical manufacturing; excipients
(This special issue belongs to the Section Physical Pharmacy and Formulation)
Development of Vectors for Drug and Gene Delivery via the Nasal Route
edited by Flávia Nathiely Silveira Fachel and Roselena Silvestri Schuh
submission deadline 31 Aug 2025 | Viewed by 411 | Submission Open
Keywords: nasal route; nose-to-brain; nanotechnology-based delivery systems; nanoparticles; nanoemulsions; liposomes; viral vectors; nonviral vectors; mucoadhesive polymers; permeation enhancers; transmucosal delivery
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Targeting Protein Aggregation and Degradation in Age-Related Diseases
edited by Martín Hugo and
submission deadline 31 Aug 2025 | Viewed by 342 | Submission Open
Keywords: aging; aggregation inhibitor; alzheimer disease; amyloidoses; antioxidant compounds; anti-inflammatory; autophagy; α -synucleinopathies; cell signaling; cysteine; drug delivery; drug discovery; high-throughput screening; nanotechnology; neurodegenerative diseases; oxidation; parkinson’ s disease; phase separation; protease inhibitor; proteasome; proteostasis; protein aggregation; redox; stress granule
(This special issue belongs to the Section Drug Targeting and Design)
Advanced Drug Delivery Systems for Targeted Immunotherapy
edited by , and Peng Zhang
submission deadline 31 Aug 2025 | Viewed by 339 | Submission Open
Keywords: drug delivery systems; Immunotherapy; nanocarrier; bioavailability
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Effects of Obesity on Pharmacokinetics
edited by Stefan Engeli
submission deadline 31 Aug 2025 | Viewed by 337 | Submission Open
Keywords: obesity; pharmacokinetics; ADME
(This special issue belongs to the Section Pharmacokinetics and Pharmacodynamics)
Research on Protein-Based Nanoparticles and Their Pharmaceutical Applications
edited by and Hachemi Kadri
submission deadline 31 Aug 2025 | Viewed by 336 | Submission Open
Keywords: nanoparticles; protein; protein derivatives; targeted delivery; therapeutics; diagnostics
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Advancing Biomedical Research: The Critical Role of Novel Alternative Methods (NAMs) in Replacing Animal Models in Pharmaceutical Research submission deadline 31 Aug 2025 | Viewed by 303 | Submission Open
Keywords: 3R policy; 2D models using cell lines; cell and tissue culture; 3D models of cell and tissue culture; organs-on-a-chip; stem cell research; computational and mathematical models; non-invasive diagnostic imaging; stem cell research; toxicology; drug delivery systems; drug delivery
(This special issue belongs to the Section Pharmaceutical Technology, Manufacturing and Devices)
Research on the Design and Development of Anti-Tumor Drug Delivery Vehicles
edited by
submission deadline 31 Aug 2025 | Viewed by 290 | Submission Open
Keywords: anti-tumor drugs; drug delivery vehicles; nanoparticles; cancer treatment; targeted therapy; drug efficacy; delivery system optimization; tumor microenvironment; neurocognitive aspects; drug design
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Targeting the Lungs: The Potential of Aerosolized Medications in Gene Therapy
edited by Tristan Montier and Rosy Ghanem
submission deadline 31 Aug 2025 | Viewed by 280 | Submission Open
Keywords: aerosol delivery; gene therapy; lipid-based gene delivery; viral vectors; pulmonary disease; nucleic acid-based vaccines
(This special issue belongs to the Section Gene and Cell Therapy)
Advanced Algorithms for Small-Molecule Therapeutics Development
edited by and Corina Andrei
submission deadline 31 Aug 2025 | Viewed by 268 | Submission Open
Keywords: small-molecule drug development; advanced computational algorithms; pharmacokinetics modeling; toxicity prediction algorithms; multi-target drug development; predictive modeling for drug efficacy; algorithm-driven pharmacology; computational drug development; drug safety profiling
(This special issue belongs to the Section Pharmacokinetics and Pharmacodynamics)
Polymeric Hydrogels and Bioactive Matrices for Drug Delivery and Wound Management
edited by
submission deadline 31 Aug 2025 | Viewed by 231 | Submission Open
Keywords: polymeric hydrogels; bioactive matrices; drug delivery systems; wound management; biocompatibility; hydrogel scaffolds; controlled release; tissue engineering; bioactive matrices
(This special issue belongs to the Section Drug Delivery and Controlled Release)
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