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Most Cited

  • Review
  • Open Access
585 Citations
76,196 Views
46 Pages

Artificial Intelligence in Pharmaceutical Technology and Drug Delivery Design

  • Lalitkumar K. Vora,
  • Amol D. Gholap,
  • Keshava Jetha,
  • Raghu Raj Singh Thakur,
  • Hetvi K. Solanki and
  • Vivek P. Chavda

Artificial intelligence (AI) has emerged as a powerful tool that harnesses anthropomorphic knowledge and provides expedited solutions to complex challenges. Remarkable advancements in AI technology and machine learning present a transformative opport...

  • Review
  • Open Access
417 Citations
21,510 Views
69 Pages

Chitosan: A Potential Biopolymer in Drug Delivery and Biomedical Applications

  • Nimeet Desai,
  • Dhwani Rana,
  • Sagar Salave,
  • Raghav Gupta,
  • Pranav Patel,
  • Bharathi Karunakaran,
  • Amit Sharma,
  • Jyotsnendu Giri,
  • Derajram Benival and
  • Nagavendra Kommineni

Chitosan, a biocompatible and biodegradable polysaccharide derived from chitin, has surfaced as a material of promise for drug delivery and biomedical applications. Different chitin and chitosan extraction techniques can produce materials with unique...

  • Review
  • Open Access
273 Citations
23,639 Views
34 Pages

Solid Lipid Nanoparticles vs. Nanostructured Lipid Carriers: A Comparative Review

  • Cláudia Viegas,
  • Ana B. Patrício,
  • João M. Prata,
  • Akhtar Nadhman,
  • Pavan Kumar Chintamaneni and
  • Pedro Fonte

Solid–lipid nanoparticles and nanostructured lipid carriers are delivery systems for the delivery of drugs and other bioactives used in diagnosis, therapy, and treatment procedures. These nanocarriers may enhance the solubility and permeability...

  • Review
  • Open Access
273 Citations
19,358 Views
26 Pages

Triple Negative Breast Cancer Treatment Options and Limitations: Future Outlook

  • Onyinyechi Obidiro,
  • Gantumur Battogtokh and
  • Emmanuel O. Akala

Triple negative breast cancer (TNBC) has a negative expression of estrogen receptors (ER), progesterone receptors (PR), and human epidermal growth factor receptors (HER2). The survival rate for TNBC is generally worse than other breast cancer subtype...

  • Review
  • Open Access
244 Citations
22,381 Views
22 Pages

Advances in Oral Drug Delivery Systems: Challenges and Opportunities

  • Jie Lou,
  • Hongli Duan,
  • Qin Qin,
  • Zhipeng Teng,
  • Fengxu Gan,
  • Xiaofang Zhou and
  • Xing Zhou

The oral route is the most preferred route for systemic and local drug delivery. However, the oral drug delivery system faces the harsh physiological and physicochemical environment of the gastrointestinal tract, which limits the bioavailability and...

  • Review
  • Open Access
194 Citations
23,694 Views
36 Pages

A biomarker is any measurable biological moiety that can be assessed and measured as a potential index of either normal or abnormal pathophysiology or pharmacological responses to some treatment regimen. Every tissue in the body has a distinct biomol...

  • Review
  • Open Access
191 Citations
11,729 Views
31 Pages

Natural Polymer-Based Hydrogels: From Polymer to Biomedical Applications

  • Lingling Zhao,
  • Yifan Zhou,
  • Jiaying Zhang,
  • Hongze Liang,
  • Xianwu Chen and
  • Hui Tan

Hydrogels prepared from natural polymer have attracted extensive attention in biomedical fields such as drug delivery, wound healing, and regenerative medicine due to their good biocompatibility, degradability, and flexibility. This review outlines t...

  • Review
  • Open Access
177 Citations
16,504 Views
28 Pages

Recent Advances in Targeted Drug Delivery Strategy for Enhancing Oncotherapy

  • Jianmin Li,
  • Qingluo Wang,
  • Guoyu Xia,
  • Nigela Adilijiang,
  • Ying Li,
  • Zhenqing Hou,
  • Zhongxiong Fan and
  • Jinyao Li

Targeted drug delivery is a precise and effective strategy in oncotherapy that can accurately deliver drugs to tumor cells or tissues to enhance their therapeutic effect and, meanwhile, weaken their undesirable side effects on normal cells or tissues...

  • Review
  • Open Access
173 Citations
12,091 Views
33 Pages

Chitosan-Based Biomaterials for Tissue Regeneration

  • Yevgeniy Kim,
  • Zharylkasyn Zharkinbekov,
  • Kamila Raziyeva,
  • Laura Tabyldiyeva,
  • Kamila Berikova,
  • Dias Zhumagul,
  • Kamila Temirkhanova and
  • Arman Saparov

Chitosan is a chitin-derived biopolymer that has shown great potential for tissue regeneration and controlled drug delivery. It has numerous qualities that make it attractive for biomedical applications such as biocompatibility, low toxicity, broad-s...

  • Review
  • Open Access
171 Citations
112,191 Views
34 Pages

Ashwagandha (Withania somnifera)—Current Research on the Health-Promoting Activities: A Narrative Review

  • Paulina Mikulska,
  • Marta Malinowska,
  • Miłosz Ignacyk,
  • Paweł Szustowski,
  • Joanna Nowak,
  • Karolina Pesta,
  • Monika Szeląg,
  • Damian Szklanny,
  • Eliza Judasz and
  • Gabriela Kaczmarek
  • + 4 authors

In recent years, there has been a significant surge in reports on the health-promoting benefits of winter cherry (Withania somnifera), also known as Ashwagandha. Its current research covers many aspects of human health, including neuroprotective, sed...

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Pharmaceutics - ISSN 1999-4923