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  • Review
  • Open Access
29 Citations
22,166 Views
40 Pages

Phenyliodine(III)diacetate (PIDA): Applications in Organic Synthesis

  • Ravi Varala,
  • Vittal Seema and
  • Narsimhaswamy Dubasi

23 December 2022

One of the hypervalent iodines most widely used as an oxidizing agent in organic chemistry is (diacetoxyiodo)benzene (PhI(OAc)2), also known as (DAIB), phenyliodine(III) diacetate (PIDA). In this septennial mini-review, the authors have concisely and...

  • Review
  • Open Access
18 Citations
21,669 Views
48 Pages

A Review on Barbituric Acid and Its Derivatives: Synthesis, Reactions, and Bio-Applications

  • Navneet Kaur,
  • Manvinder Kaur,
  • Harvinder Singh Sohal,
  • Haesook Han and
  • Pradip K. Bhowmik

5 September 2024

Barbituric acid is a heterocyclic compound with various pharmacological and biological applications. This review paper provides a comprehensive overview of barbituric acid’s synthesis, reactions, and bio-applications, highlighting its multiface...

  • Review
  • Open Access
20 Citations
19,661 Views
34 Pages

Aldehydes: What We Should Know About Them

  • Alessia Catalano,
  • Annaluisa Mariconda,
  • Assunta D’Amato,
  • Domenico Iacopetta,
  • Jessica Ceramella,
  • Maria Marra,
  • Carmela Saturnino,
  • Maria Stefania Sinicropi and
  • Pasquale Longo

21 October 2024

From Egyptian mummies to the Chanel N° 5 perfume, aldehydes have been used for a long time and continue to impact our senses in a wide range of perfumes, foods, and beverages. Aldehydes represent one of the categories of volatile organic compound...

  • Review
  • Open Access
6 Citations
10,378 Views
49 Pages

An Overview of Quinolones as Potential Drugs: Synthesis, Reactivity and Biological Activities

  • Ayoub El-mrabet,
  • Amal Haoudi,
  • Youssef Kandri-Rodi and
  • Ahmed Mazzah

3 April 2025

Quinolones represent one of the largest classes of synthetic antibiotics used in both human and veterinary medicine. Since the discovery of nalidixic acid, a substantial body of research has been carried out on quinolones, resulting in the synthesis...

  • Review
  • Open Access
14 Citations
9,671 Views
22 Pages

Recent Developments Towards the Synthesis of Triazole Derivatives: A Review

  • Issam Ameziane El Hassani,
  • Khouloud Rouzi,
  • Anouar Ameziane El Hassani,
  • Khalid Karrouchi and
  • M’hammed Ansar

24 October 2024

The triazole scaffold is a crucial component of heterocyclic chemistry, serving as a basic building block in organic synthesis, materials science, and medicinal chemistry. Triazole is a five-membered ring composed of three nitrogen atoms and two carb...

  • Review
  • Open Access
35 Citations
7,961 Views
41 Pages

Advances in Organic Materials for Next-Generation Optoelectronics: Potential and Challenges

  • Ghazi Aman Nowsherwan,
  • Qasim Ali,
  • Umar Farooq Ali,
  • Muhammad Ahmad,
  • Mohsin Khan and
  • Syed Sajjad Hussain

11 November 2024

This review provides a comprehensive overview of recent advancements in the synthesis, properties, and applications of organic materials in the optoelectronics sector. The study emphasizes the critical role of organic materials in the development of...

  • Review
  • Open Access
1 Citations
7,859 Views
41 Pages

Synthesis and Biological Activity of 5-Substituted-2,4-dihydro-1,2,4-triazole-3-thiones and Their Derivatives

  • Abdukhakim A. Ziyaev,
  • Sobirdjan A. Sasmakov,
  • Turdibek T. Toshmurodov,
  • Jaloliddin M. Abdurakhmanov,
  • Saidazim A. Ikramov,
  • Shukhrat Sh. Khasanov,
  • Oybek N. Ashirov,
  • Mavluda A. Ziyaeva and
  • Dilrabo B. Begimqulova

4 September 2025

Derivatives of 1,2,4-triazole-3-thione exhibit a variety of biological activities, including antimicrobial (e.g., compounds 31d–k, 32d, 36f), antitumor (e.g., 71, 77a–c, 82g, 94h), anti-inflammatory, analgesic (100a, 102, 105), antidiabet...

  • Review
  • Open Access
9 Citations
7,106 Views
23 Pages

5 December 2024

Pyrazole and tetrazole are among the most important heterocyclic members of the azole family. Over the past decade, these N-heterocycles and their derivatives have demonstrated specific properties that give them potent applications in several fields...

  • Communication
  • Open Access
4 Citations
6,978 Views
10 Pages

27 April 2023

We describe a novel two-step approach for the synthesis of compounds with a hydroxyl-amide group (hydroxamic acids), which are widely known for their biological activity (histone deacetylase inhibitors, matrix metalloproteinases inhibitors and others...

  • Review
  • Open Access
2 Citations
6,836 Views
23 Pages

4-Hydroxy-2-pyrones: Synthesis, Natural Products, and Application

  • Vladislav V. Fedin,
  • Dmitrii L. Obydennov,
  • Sergei A. Usachev and
  • Vyacheslav Y. Sosnovskikh

15 December 2023

4-Hydroxy-2-pyrones are of interest as potential biorenewable molecules for a sustainable transition from biomass feedstock to valuable chemical products. This review focuses on the methodologies for the synthesis of 4-hydroxy-2-pyrones published ove...

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Organics - ISSN 2673-401X