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  • Article
  • Open Access

Remote Induction Heating of Metal Implants for Noninvasive Elimination of Pseudomonas aeruginosa Biofilm, Augmented by Tobramycin

  • Haydar A. S. Aljaafari,
  • Parham Parnian,
  • Nadia I. Abdulwahhab,
  • Jaymes Van Dyne and
  • Eric Nuxoll

Thermal shock is a promising new approach to eliminating biofilm infections on medical implants without surgically replacing the device. Most studies determining the minimum necessary thermal shock used immersion in hot media to provide precise, rapi...

(This article belongs to the Special Issue Antibacterial Research and Biofilm Formation)
  • Article
  • Open Access

Genomic Analysis of an IMP-1-Producing Atlantibacter hermannii Bloodstream Isolate Carrying a Transferable blaIMP-1-Harbouring IncHI2/pST1 Plasmid Related to Historical Enterobacterales Plasmids in Japan

  • Takashi Okanda,
  • Natsuki Yumura,
  • Daishu Fukushima,
  • Niinyo Nakajima,
  • Tetsuo Yamaguchi,
  • Yosuke Tanaka,
  • Kenta Katsumata,
  • Kotaro Aoki,
  • Takuro Koshikawa and
  • Hiromu Takemura
  • + 4 authors

Atlantibacter hermannii is an uncommon member of the Enterobacterales rarely associated with human infection, and genomic data on antimicrobial resistance in this species remain limited. Carbapenemase-producing A. hermannii isolates have rarely been...

(This article belongs to the Special Issue Advances in Clinical Infections and Antimicrobial Resistance)
  • Review
  • Open Access

Entomopathogenic fungi (EPF) are promising microbial control agents, but high laboratory virulence alone does not ensure successful development into reliable mycoinsecticides. This review proposes a sequential multi-trait framework organized around t...

(This article belongs to the Section Plant Microbe Interactions)
  • Article
  • Open Access

Analysis of Microbial Communities Associated with Drought-Resistant Plants Using 16S rRNA Sequencing

  • Irina Lyapina,
  • Igor Fesenko,
  • Elena Chizhevskaya,
  • Margarita Khudyaeva,
  • Nina Lapenko,
  • Igor Tikhonovich and
  • Vladimir K. Chebotar

Microbial communities associated with plants influence their growth, physiological functions, and resistance to pathogens and environmental stresses. Nevertheless, the identification of beneficial bacterial taxa that support plant resilience to envir...

(This article belongs to the Section Molecular Microbiology and Immunology)
  • Review
  • Open Access

Aeromonas salmonicida is an important threat to the sustainability of aquaculture production and a major contributor to antimicrobial resistance, which has encouraged bacteriophage therapy. This review evaluated the current evidence base for bacterio...

(This article belongs to the Special Issue Research on Bacterial Pathogens in Fish)
  • Article
  • Open Access

High Lipid Yield and Efficient Biodiesel Production from Fusarium solani 102F Using Waste Eggshell as Biocatalyst

  • Doaa M. A. Khalil,
  • Mostafa Abdelrahman,
  • Ha Duc Chu,
  • Sudisha Jogaiah,
  • Lam-Son Phan Tran and
  • Noha M. Kamel

Oleaginous fungi offer a sustainable alternative to plant-based feedstocks for biodiesel production, yet their industrial potential remains limited due to high processing costs and strain-dependent performance. Here, we report that the endophytic fun...

(This article belongs to the Section Microbial Biotechnology)
  • Review
  • Open Access

Barrier Protection, Skin Microbiome, and Diaper Dermatitis in Infants: Current Evidence and Future Perspectives—A Narrative Review

  • Oznur Ozlem Ibrahimoglu,
  • Mehmet Serhan Boduroglu,
  • Ismail Aslan,
  • Ertugrul Osman Bursalıoğlu,
  • Ayse Nilhan Atsu and
  • Ronayi Coskun

Diaper dermatitis is one of the most common inflammatory skin conditions in infancy. It develops through the combined effects of moisture, friction, irritants, and disruption of the epidermal barrier. This review aimed to evaluate recent evidence on...

(This article belongs to the Special Issue Skin Microbiome)
  • Article
  • Open Access

Genomic Characterization of the Probiotic Limosilactobacillus mucosae CRL2069 Isolated from Feedlot Cattle Feces

  • Cecilia M. Aristimuño Ficoseco,
  • Natalia Carrasco,
  • Marco Montemurro,
  • Daniele Chieffi,
  • Silvina G. Fadda,
  • Maria E. F. Nader-Macias,
  • Vincenzina Fusco,
  • Graciela M. Vignolo and
  • Francesca Fanelli

Limosilactobacillus mucosae (L.) CRL2069, isolated from feedlot cattle feces, has previously exhibited high performance when used as a probiotic in animals. To investigate the genetic bases underlying its probiotic potential, complete genome sequenci...

(This article belongs to the Special Issue Characterizing Microorganisms Across Food, Feed and Environmental Systems: A One Health Perspective)
  • Article
  • Open Access

Changes in Antimicrobial Resistance in Bloodstream Infections During the COVID-19 Pandemic—A Retrospective Study from a Tertiary Care Hospital

  • Rodica Stela Lumpan,
  • Daniela Tălăpan,
  • Alina Maria Borcan,
  • Mihai Stoica,
  • Mihai Octavian Dan,
  • Alexandru Rafila and
  • Victoria Aramă

The COVID-19 pandemic led to major repurposing of healthcare settings, especially Infectious Diseases hospitals, by redirecting care towards SARS-CoV-2-infected patients. However, frequent bacterial infections overlapping the viral background led to...

(This article belongs to the Special Issue Infectious Disease Surveillance in Romania: Third Edition)
  • Article
  • Open Access

Schizochytrium oil (SO) is rich in docosahexaenoic acid (DHA), but its ruminal effects in sheep remain unclear. Twenty Hu lambs were fed CK or SO diets for 84 d. The CK diet contained 4% palm oil, 31.43% neutral detergent fiber (NDF), and 5.58% ether...

(This article belongs to the Special Issue Rumen Microorganisms)
  • Article
  • Open Access

Horizontal transfer of blaKPC-bearing plasmids contributes significantly to the dissemination of carbapenem resistance among Enterobacterales; however, the influence of mechanistically distinct antibiotics on this process remains incompletely underst...

(This article belongs to the Special Issue Current Updates on Multidrug-Resistant Gram-Negative Bacterial Infections)
  • Article
  • Open Access

Contrasting Seed Protein Phenotypes Are Associated with Nodulation and Rhizosphere Microbiome Assembly in Soybean

  • Jiyuan Guo,
  • Lixue Wang,
  • Song Liu,
  • Hong Xue,
  • Weiwei Zhang,
  • Xuepeng Fu and
  • Quanzhong Dong

Soybean seed protein content varies with genotype, nitrogen acquisition, and environmental conditions. Associations between belowground microbiota and seed protein content remain insufficiently characterized. We compared three high-protein cultivars...

(This article belongs to the Section Plant Microbe Interactions)
  • Article
  • Open Access

Salivary Microbiota and Network Alterations in Oral Lichen Planus with Candida Compared to Healthy Controls

  • Hye-Min Ju,
  • Yong-Woo Ahn,
  • Soo-Min Ok,
  • Sung-Hee Jeong,
  • Ji-Young Joo and
  • Hee Sam Na

Background: Oral lichen planus (OLP) is a chronic immune-mediated mucosal disorder frequently accompanied by Candida colonization. However, the polymicrobial interactions and network alterations underlying this association remain poorly understood. T...

(This article belongs to the Special Issue Oral Microbiomes and Host Health)
  • Article
  • Open Access

Site- and Compartment-Associated Differentiation of Root Microbiomes in Rhododendron yunnanense

  • Jian Dong,
  • Zhaosheng Gao,
  • Liu Yang,
  • Yawen Wu,
  • Tian Bai,
  • Yan Dong and
  • Jingli Zhang

Root-associated microbiomes vary across environmental settings and root compartments, but these patterns remain poorly understood in wild woody plants. Here, we compared bacterial and fungal communities in the rhizosphere and root endosphere of Rhodo...

(This article belongs to the Special Issue Advances in the Plant Microbiome: Rhizosphere, Endosphere and Phyllosphere, Second Edition)
  • Article
  • Open Access

Molecular and Histopathological Findings of Giardia duodenalis in Rodents and Bats from the Atlantic Forest and Cerrado of Southeastern Brazil

  • Marcos Tobias de Santana Miglionico,
  • Bruno Pires Miranda,
  • Sócrates Fraga da Costa Neto,
  • Ricardo Moratelli,
  • João Marcos da Silva Barbosa,
  • Teresa Cristina Bergamo do Bomfim and
  • Helena Lúcia Carneiro Santos

Giardia duodenalis is a globally distributed intestinal protozoan infecting humans and animals. This study investigated its occurrence, genetic diversity, and histopathological findings in rodents and bats from the Atlantic Forest and Cerrado of sout...

(This article belongs to the Topic Advances in Infectious and Parasitic Diseases of Animals)
  • Article
  • Open Access

Neurological Complications and Viral Myositis in Pediatric Patients with Influenza Infection Attending a Tertiary Hospital in Madrid

  • Paula Cabrera Cascajero,
  • Nieves Dueñas Sánchez-Valdemoro,
  • Alessandra G. Villanueva Guerra,
  • Guillermo F. Ruiz-Ocaña de las Cuevas,
  • Marta Illán Ramos,
  • Adrián García Ron,
  • Arantxa Berzosa Sánchez,
  • Eva Arias Vivas and
  • José T. Ramos Amador

Background: Influenza infection in children may be associated with neurological complications, including seizures and encephalitis, as well as suspected acute viral myositis, which may result in significant morbidity. Objective: This study aimed to e...

(This article belongs to the Special Issue Diagnosis, Treatment and Prevention of Viral Infections)
  • Article
  • Open Access

Epidemiology and Predictors of 90-Day Mortality in Patients with Clostridioides difficile Infection: A Retrospective Single-Center Study from Galati, Romania

  • Pantelie Nicolcescu,
  • Gabriel-Valeriu Popa,
  • Mădălina-Nicoleta Matei,
  • Alina Plesea-Condratovici,
  • Alina-Viorica Iancu and
  • Manuela Arbune

Background: Clostridioides difficile infection (CDI) is associated with substantial morbidity and mortality, but data on 90-day mortality after hospitalization from Romania remain limited. This study characterized hospitalized patients with CDI at a...

(This article belongs to the Special Issue Infectious Disease Surveillance in Romania: Third Edition)
  • Article
  • Open Access

Loma salmonae is a gill-infecting microsporidian long recognized in Oncorhynchus species across North America, Europe, and Japan (masu/yamame salmon), but molecular confirmation in rainbow trout, or in any other salmonid host, in Korea has not previo...

(This article belongs to the Special Issue Infectious Diseases in Aquaculture, 2nd Edition)
  • Article
  • Open Access

Ocean acidification (OA), driven by global climate change together with pollution from organic contaminants, is increasing the ecological risk faced by coral reef ecosystems. The coral holobiont comprises diverse microbial communities that collective...

(This article belongs to the Special Issue Microbiomes and Host Health: The Importance of Host Self-Completion with Microbiota)
  • Article
  • Open Access

Exocarpium Citri grandis, derived from Citrus maxima var. Tomentosa, is a precious traditional Chinese medicinal herb. However, foot rot, a severe soil-borne disease, threatens the sustainable cultivation of this crop. This exploratory study investig...

(This article belongs to the Section Plant Microbe Interactions)
  • Article
  • Open Access

Antimicrobial Resistance, β-Lactamases, and Virulence-Associated Genes in Clinical Escherichia coli Isolates from a Pediatric Tertiary-Care Hospital in Honduras

  • Nancy Alvarez-Corrales,
  • Daniela Chavez-Bulnes,
  • Bryan Ortiz,
  • Jorge Carrasco,
  • Juan Rosales-Tamashiro,
  • Milena Videa Galo,
  • Marco Moncada,
  • María Félix Rivera,
  • Daniela Rivera-Pineda and
  • Manuel G. Ballesteros-Monrreal
  • + 1 author

The co-occurrence of antimicrobial resistance and virulence in Escherichia coli threatens the treatment of pediatric infections, particularly in regions with limited molecular data. We characterized 67 clinical isolates recovered at a tertiary-care p...

(This article belongs to the Special Issue Pediatric Infectious Diseases: Diagnostics, Antimicrobial Resistance, Pathogenesis, and Vaccine Development)
  • Article
  • Open Access

Aichivirus A Infection Associated with Severe Enteric and Respiratory Disease in a Captive White Lion (Panthera leo)

  • Yushan Ding,
  • Yajiang Wu,
  • Fen Shan,
  • Niu Zhou,
  • Mengna Lv,
  • Chen Wang,
  • Minting Liu,
  • Wanping Li,
  • Wu Chen and
  • Zujin Chen

Kobuviruses are emerging enteric pathogens with broad host ranges, yet their pathogenic potential in wild large felids remains largely unexplored. Here, we report the first case of severe enteric and respiratory disease associated with AiV-A infectio...

(This article belongs to the Special Issue Molecular Detection, Genotyping and Surveillance of Animal Pathogens)
  • Article
  • Open Access

Rhamnolipids and Essential Oils: A New Approach to Managing Bacteria Associated with Skin Diseases

  • Lucas Araujo Leite,
  • Maria Olimpia Pereira Sereia,
  • Gabriel Barbieri Mestieri,
  • Raphael Culim Neves,
  • Aline Martins dos Santos,
  • Suzana Gonçalves Carvalho,
  • Carolina Rosai Mendes,
  • Marlus Chorilli,
  • Guilherme Dilarri and
  • Jonas Contiero

The rise of antimicrobial-resistant pathogens has increased interest in biologically derived compounds for treating dermal infections. This study evaluates the effect of rhamnolipid, a biosurfactant produced by Pseudomonas aeruginosa, in combination...

(This article belongs to the Special Issue Modern Microbial Technology, Development and Applications)
  • Article
  • Open Access

High Conservation of the Human Metapneumovirus Fusion Protein in Contemporary Global Sequences Supports Its Continued Relevance for Therapeutic and Prophylactic Consideration

  • Vancheswaran Gopalakrishnan,
  • Emma Schaefer,
  • John Patterson,
  • Tyler Brady,
  • Joseph R. Francica,
  • Anna S. Kushnir,
  • Ondrej Podlaha,
  • Katie Streicher,
  • Taylor S. Cohen and
  • Kevin M. Tuffy
  • + 1 author

Human metapneumovirus (hMPV) is associated with severe disease in young children, older adults, and medically high-risk individuals. The hMPV F protein is highly immunogenic and a well-established target of neutralizing antibodies. In-depth hMPV surv...

(This article belongs to the Section Molecular Microbiology and Immunology)
  • Article
  • Open Access

When Testing Went Quiet, the Sewers Kept Talking: A Five-Year SARS-CoV-2 Wastewater Surveillance from Munich

  • Jasmin Javanmardi,
  • Jessica Neusser,
  • Raquel Rubio-Acero,
  • Sebastian Kachel,
  • Karina Wallrafen-Sam,
  • Jessica Hintze,
  • Ivana Paunovic,
  • Irene Charlotte Schoof,
  • Thomas Kletke and
  • Andreas Wieser
  • + 13 authors

Wastewater-based epidemiology (WBE) was introduced early in the COVID-19 pandemic to provide continuous, anonymous, population-level information on SARS-CoV-2 circulation at a time when individual testing was constrained by shortages of reagents, sta...

(This article belongs to the Special Issue Surveillance of Health-Relevant Pathogens Employing Wastewater)
  • Article
  • Open Access

SARS-CoV-2 Breakthrough Infection Reveals Platform-Associated Long-Term Immune Remodeling in a Central Asian Cohort

  • Lyudmila Akhmaltdinova,
  • Makhabbat Bekbossynova,
  • Kuanysh Dossybayeva,
  • Ainur Tauekelova,
  • Aliya Sailybayeva,
  • Irina Mekhantseva,
  • Iskander Isgandarov and
  • Dimitri Poddighe

This study aimed to evaluate platform-specific immune memory trajectories in patients with breakthrough COVID-19 over a 12-month period. This prospective longitudinal study enrolled adults hospitalized with PCR-confirmed COVID-19. Participants were s...

(This article belongs to the Special Issue Viral Immunology in an Unequal World: Bridging Disparities from Mechanisms to Populations)
  • Article
  • Open Access

Oral Microbiota Dominance in Allogeneic Hematopoietic Stem Cell Transplantation: Dynamics, Predictors, and Clinical Implications in a Multicenter Study

  • Danielle Amanda Niz Alvarez,
  • Marcus Vinicius Niz Alvarez,
  • Alexandre Soares Ferreira Junior,
  • Welinton Yoshio Hirai,
  • Nathalia Linares Silva,
  • Larissa da Silva Souza Cordeiro,
  • Luiza Dias Machado,
  • Rozana Mesquita Ciconelli,
  • Joao Victor Piccolo Feliciano and
  • Gislane Lelis Vilela de Oliveira
  • + 3 authors

Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is an important therapeutic strategy for hematological malignancies and other diseases but remains associated with substantial morbidity and mortality. Although microbial dominance has be...

(This article belongs to the Special Issue Oral Microbiomes and Host Health)
  • Review
  • Open Access

Artificial Intelligence for Microbial Colony Analysis: Plate-Reading Challenges, Method Selection, and Validation

  • Xue Li,
  • Jing Wang,
  • Meng Xiao,
  • Peiyao Jia,
  • Dingding Li,
  • Yu Hu,
  • Meng Shi,
  • Qiang Xu,
  • Yi Lu and
  • Yingchun Xu

Microbial colony analysis is routinely used in clinical microbiology, pharmaceutical quality control, food safety, and environmental monitoring. Colony enumeration remains challenging because real-world plates frequently show crowding, size variation...

(This article belongs to the Special Issue Advancing Microbial Biotechnology)
  • Article
  • Open Access

Soil acidification strongly influences the ecology of terrestrial ammonia-oxidizing archaea (AOA). Within this group, the Nitrososphaera-related alpha (NS-α) and delta (NS-δ) lineages exhibit pronounced pH-associated ecological differenti...

(This article belongs to the Section Environmental Microbiology)
  • Review
  • Open Access
130 Views
37 Pages

Panax ginseng Meyer has been commonly used as a traditional herbal medicine in East Asia for millennia. Ginsenosides Rg1 and Rb1 are the primary pharmacologically active ingredients and exhibit broad therapeutic efficacy against immunometabolic disor...

(This article belongs to the Section Gut Microbiota)
  • Article
  • Open Access
103 Views
26 Pages

Long-term continuous cropping often degrades soil and reduces productivity, yet how soil properties and microbial communities respond in continuous tree peony monoculture remains poorly understood. Herein, soil physicochemical properties were investi...

(This article belongs to the Special Issue Agricultural Microbial Ecology: Plant–Soil–Microbe Interactions)
  • Article
  • Open Access
9 Views
14 Pages

Antimicrobial Resistance and Genetic Characteristics of Ciprofloxacin-Resistant Escherichia coli from Suckling and Weaned Piglet Housing Areas in Korea

  • Oyoung Kwon,
  • Da-Hye Ryu,
  • Hyun-Jung Ahn,
  • Su-Jin Choe,
  • Min-Gyu Kim,
  • You-Kyung Go,
  • Su-Bin Kim,
  • Soochong Kim,
  • Seung-Hun Lee and
  • Kwang-Won Seo
  • + 1 author

In swine production systems, antimicrobial exposure and management conditions vary across production stages, particularly during the transition from suckling to weaning, which may influence the selection and persistence of antimicrobial-resistant bac...

(This article belongs to the Special Issue Bacterial Infections and Antimicrobial Resistance in Animal Populations)
  • Case Report
  • Open Access
116 Views
17 Pages

Sino-Cranial Infection Caused by Curvularia spicifera in a Young Adult Without Overt Immunosuppression: A Case Report and Review of the Literature

  • Arianna Emiliozzi,
  • Alessandro Capone,
  • Marina Selleri,
  • Carlo Giacomo Palazzo,
  • Antonella Vulcano,
  • Chiara Temperoni,
  • Alessandra Lodi,
  • Davide Luglietto,
  • Assunta Gallo and
  • Stefania Cicalini
  • + 2 authors

Curvularia species are melanized dematiaceous molds widely distributed in soil, plants, and decaying organic matter. Human infections are uncommon and typically involve the paranasal sinuses, skin, cornea, or respiratory tract, whereas central nervou...

(This article belongs to the Section Medical Microbiology)
  • Article
  • Open Access
75 Views
20 Pages

Escherichia marmotae Dominates the Global Distribution of cdtABC Carriers in the Human Gut

  • Zhuo Pan,
  • Ziang Wang,
  • Songlin Zhao,
  • Guangjun Chen,
  • Daoyuan Wu and
  • Qingxin Xia

The gut microbiota can influence colorectal cancer through microbial metabolism, immune regulation and direct damage to host DNA. Previous experimental studies have shown that cytolethal distending toxin (CDT) can damage host DNA and promote colorect...

(This article belongs to the Special Issue Microbial Communities and Their Functions in the Environment)
  • Article
  • Open Access
113 Views
19 Pages

Vaginal Cytokine Profiles Associated with High-Risk Human Papillomavirus, Sexually Transmitted Microbe Co-Detection, and Cervical Lesions

  • Habtamu Biazin Kebede,
  • Dareskedar Tsehay,
  • Selamawit Mekuria,
  • Ola Forslund,
  • Christer Borgfeldt,
  • Mats Jerkeman,
  • Tamrat Abebe and
  • Adane Mihret

Background: Persistent hrHPV infection is the necessary cause of cervical cancer, but local immune responses and sexually transmitted infections or genital mycoplasma may influence viral persistence and lesion progression. This study examined vaginal...

(This article belongs to the Section Molecular Microbiology and Immunology)
  • Article
  • Open Access
88 Views
27 Pages

Mycoplasmopsis bovis is a major causative agent of bovine mastitis and causes substantial economic losses in the dairy industry because of the chronic and refractory nature of the infection. This study aimed to determine how M. bovis PG45 infection d...

(This article belongs to the Section Veterinary Microbiology)
  • Article
  • Open Access
216 Views
16 Pages

Sex-Specific Cytokine Profiles Associated with Viral Load and Disease Severity in Patients with Severe Fever with Thrombocytopenia Syndrome

  • Lianfeng Li,
  • Ling Qiu,
  • Yifei Wang,
  • Qing Dong,
  • Mingzhu Zhang,
  • Peiyu Zhen,
  • Mengying Gao,
  • Shan Lu,
  • Di Zhao and
  • Jie Qian
  • + 4 authors

Background: Severe fever with thrombocytopenia syndrome (SFTS) is a severe tick-borne viral disease characterized by dysregulated host immune responses. Although previous studies have suggested sex-related differences in immune responses in SFTS, the...

(This article belongs to the Section Medical Microbiology)
  • Article
  • Open Access
126 Views
20 Pages

Virulence Signatures and Biofilm-Forming Capacity of ESBL-Producing Escherichia coli in Wastewater and Agricultural Environments

  • Monica S. Sellars,
  • Courtney W. Reggans,
  • Ajah A. Alford,
  • Alyssa J. Harris,
  • Jordan C. Deutschlander and
  • Mabel Kamweli Aworh

The persistence of extended-spectrum β-lactamase (ESBL)-producing E. coli in livestock and municipal wastewater systems represent a key environmental pathway for antimicrobial resistance (AMR) and virulence determinants with direct public-health...

(This article belongs to the Section Environmental Microbiology)
  • Review
  • Open Access
139 Views
35 Pages

H3 subtype avian influenza virus (AIV) is one of the most widely distributed and frequently detected low-pathogenicity avian influenza viruses (LPAIVs) in wild birds and poultry worldwide. Wild waterfowl are the natural reservoir of this virus. In re...

(This article belongs to the Special Issue Viral Diseases in Veterinary)
  • Article
  • Open Access
94 Views
15 Pages

CpxA Deletion Is Associated with Altered Polymyxin B Susceptibility and Flagellar-Associated Transcriptional Remodeling in Salmonella Typhimurium

  • Yupeng Fang,
  • Kuanjia Guo,
  • Xiaoqing Zhang,
  • Tiantian Chen,
  • Chengbin Xue,
  • Yangxinyue Zhan,
  • Ziwei Guo,
  • Cunlei Liu,
  • Hao Lin and
  • Yongsheng Liu
  • + 3 authors

Polymyxin B is considered a last-resort antibiotic for multidrug-resistant or extensively drug-resistant Gram-negative bacterial infections. Understanding the determinants of polymyxin B susceptibility in Salmonella is important for public health. Ph...

(This article belongs to the Section Antimicrobial Agents and Resistance)
  • Editorial
  • Open Access
72 Views
6 Pages

The gut microbiota has long been recognized as a critical “hidden organ” that interacts dynamically with host animals, playing irreplaceable roles in regulating nutrient metabolism, shaping immune function, and maintaining systemic health...

(This article belongs to the Special Issue Dietary and Animal Gut Microbiota)
  • Review
  • Open Access
82 Views
24 Pages

Proteobacteria: A Toolbox for Clinicians

  • William Fusco,
  • Ernesto Margarita,
  • Enrico Capuano,
  • Andrea Severino,
  • Serena Porcari,
  • Simone Varca,
  • Tiziano Galasso,
  • Elena Lener,
  • Antonio Gasbarrini and
  • Gianluca Ianiro

Proteobacteria are a phylum of Gram-negative bacteria that, although normally a minor component of the healthy gut microbiota, can be markedly increased in many conditions. Their overgrowth is in fact linked to inflammation, impaired epithelial barri...

(This article belongs to the Section Gut Microbiota)
  • Article
  • Open Access
90 Views
18 Pages

Complementary Use of Shotgun Metagenomics and Multiplex PCR for Pathogen Detection on High-Touch Surfaces

  • Mohamad Taisir Ahmad Ghiba,
  • Areej Alsheikh-Hussain,
  • Turki Essa Alzahrani,
  • Monther Alhamdoosh,
  • Abdulkarim Fahad Alhetheel,
  • Atif Hanif and
  • Saleh Ahmed Eifan

Shotgun metagenomics is being increasingly promoted as a pathogen-agnostic alternative to targeted PCR for environmental surveillance, yet its practical value on dry, low-biomass, host-dominated surfaces remains uncertain. In a companion study, we re...

(This article belongs to the Special Issue Microbial Taxonomy and Environmental Metagenomics: Diversity, Dynamics, and Functional Genes)
  • Review
  • Open Access
133 Views
15 Pages

The bacterial cytoplasm is increasingly recognized as a dynamic, out-of-equilibrium environment in which biochemical reactions occur. Here, we discuss recent advances in our understanding of the generation of microscopic forces in the cytoplasm, part...

(This article belongs to the Section Molecular Microbiology and Immunology)
  • Review
  • Open Access
76 Views
26 Pages

Proton Pump Inhibitors and the Gut Microbiota: From Mechanisms to Clinical Implications

  • Franziska Deutschbein,
  • Andrea Severino,
  • Margherita Ferrari,
  • Enrico Capuano,
  • William Fusco,
  • Simone Varca,
  • Debora Rondinella,
  • Tiziano Galasso,
  • Serena Porcari and
  • Gianluca Ianiro
  • + 1 author

Proton pump inhibitors (PPIs) are among the most widely used drugs in clinical practice. Although generally effective and well tolerated, their widespread and frequently prolonged use has raised concerns about both gastrointestinal and systemic adver...

(This article belongs to the Section Gut Microbiota)
  • Article
  • Open Access
130 Views
15 Pages

Systemic T-Cell Activation Landscapes Elicited Following Intramuscular and Intranasal Immunization with the Active NDV-Vectored Anti-COVID-19 Vaccine “Patria” in Humans

  • Claudia Carranza,
  • Alejandro Torres-Flores,
  • Dámaris P. Romero-Rodríguez,
  • Constantino López-Macías,
  • Martha Torres and
  • Esmeralda Juárez

COVID-19 vaccines remain essential for pandemic control, but antibody responses wane, and viral variants emerge. Affordable platforms enabling local manufacturing are important for equitable vaccine access in low- and middle-income countries (LMICs)....

(This article belongs to the Special Issue Viral Immunology in an Unequal World: Bridging Disparities from Mechanisms to Populations)
  • Review
  • Open Access
120 Views
27 Pages

Climate change is increasingly recognised as a driver of microbial risks and antimicrobial resistance (AMR) dynamics across environmental and human systems. This review synthesises current evidence on how climate-related factors may affect the persis...

(This article belongs to the Section Environmental Microbiology)
  • Article
  • Open Access
79 Views
14 Pages

The limited nitrogen and phosphorus concentration reduction performance of wetlands during cold weather is a global concern. To address the challenge of low nutrient removal efficiency in winter, this study introduces a hollow fiber membrane module i...

(This article belongs to the Special Issue Agricultural Microbial Ecology: Plant–Soil–Microbe Interactions)
  • Article
  • Open Access
44 Views
20 Pages

Biofilm-Forming and Multidrug-Resistant Salmonella Thompson Strains Isolated from Edible Cipangopaludina cathayensis: An Emerging Food Safety Concern in Southern China

  • Yuqiong Li,
  • Jianjie Peng,
  • Jie Zhang,
  • Haixia Lan,
  • Ying Wang,
  • Junhao Lin,
  • Shuhui Gan,
  • Xintong Li,
  • Kai Shao and
  • Ziheng Xu
  • + 2 authors

Salmonella enterica Thompson (S. Thompson) is a zoonotic foodborne pathogen causing infection in humans and animals, yet limited data exist on isolates from edible Cipangopaludina cathayensis (C. cathayensis), a key ingredient of Liuzhou Luosifen. In...

(This article belongs to the Special Issue Foodborne Pathogens: Detection, Resistance, Risk Assessment and Control)
  • Article
  • Open Access
57 Views
30 Pages

This study investigated the antibacterial properties and biofilm disruption mechanisms of five medicinal plants traditionally used in Limpopo communities for the treatment of oral infections, namely Sesamum senecioides Klotzsch, Euclea undulata Thunb...

(This article belongs to the Special Issue Advanced Research on Antimicrobial Activity of Natural Products: 2nd Edition)
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Microorganisms - ISSN 2076-2607