Next Article in Journal
Long-Term but Not Short-Term Maternal Fasting Reduces Nephron Number and Alters the Glomerular Filtration Barrier in Rat Offspring
Next Article in Special Issue
Andrographis paniculata (Burm. f.) Wall. ex Nees: An Updated Review of Phytochemistry, Antimicrobial Pharmacology, and Clinical Safety and Efficacy
Previous Article in Journal
Evaluation of In Vitro Neuronal Protection by Postconditioning with Poloxamer 188 Following Simulated Traumatic Brain Injury
Previous Article in Special Issue
Hexane Extract of Chloranthus japonicus Increases Adipocyte Differentiation by Acting on Wnt/β-Catenin Signaling Pathway
 
 
Review

Bromelain a Potential Bioactive Compound: A Comprehensive Overview from a Pharmacological Perspective

1
Department of Pharmacy, Faculty of Pharmacy, University of Dhaka, Dhaka 1000, Bangladesh
2
Department of Biology, Faculty of Mathematics and Natural Sciences, Universitas Sam Ratulangi, Manado 95115, Indonesia
3
Department of Pharmacy, International Islamic University Chittagong, Chittagong 4318, Bangladesh
4
Faculty of Pharmacy, Hasanuddin University, Makassar, Sulawesi Selatan 90245, Indonesia
5
Department of Pharmacy, University of Naples Federico II, 80131 Naples, Italy
6
Division of Pathology, ICAR-Indian Veterinary Research Institute, Izatnagar, Bareilly 243122, India
7
Department of Pharmacy, BGC Trust University Bangladesh, Chittagong 4381, Bangladesh
8
Nutrition and Bromatology Group, Department of Analytical and Food Chemistry, Faculty of Food Science and Technology, University of Vigo—Ourense Campus, E32004 Ourense, Spain
9
Department of Agricultural Sciences, University of Naples Federico II, 80055 Portici, Italy
*
Authors to whom correspondence should be addressed.
Academic Editor: Balazs Barna
Life 2021, 11(4), 317; https://doi.org/10.3390/life11040317
Received: 5 March 2021 / Revised: 26 March 2021 / Accepted: 31 March 2021 / Published: 6 April 2021
Bromelain is an effective chemoresponsive proteolytic enzyme derived from pineapple stems. It contains several thiol endopeptidases and is extracted and purified via several methods. It is most commonly used as an anti-inflammatory agent, though scientists have also discovered its potential as an anticancer and antimicrobial agent. It has been reported as having positive effects on the respiratory, digestive, and circulatory systems, and potentially on the immune system. It is a natural remedy for easing arthritis symptoms, including joint pain and stiffness. This review details bromelain’s varied uses in healthcare, its low toxicity, and its relationship to nanoparticles. The door of infinite possibilities will be opened up if further extensive research is carried out on this pineapple-derived enzyme. View Full-Text
Keywords: bromelain; Ananas comosus; pineapple; nanoparticles; proteolytic enzymes bromelain; Ananas comosus; pineapple; nanoparticles; proteolytic enzymes
Show Figures

Figure 1

MDPI and ACS Style

Chakraborty, A.J.; Mitra, S.; Tallei, T.E.; Tareq, A.M.; Nainu, F.; Cicia, D.; Dhama, K.; Emran, T.B.; Simal-Gandara, J.; Capasso, R. Bromelain a Potential Bioactive Compound: A Comprehensive Overview from a Pharmacological Perspective. Life 2021, 11, 317. https://doi.org/10.3390/life11040317

AMA Style

Chakraborty AJ, Mitra S, Tallei TE, Tareq AM, Nainu F, Cicia D, Dhama K, Emran TB, Simal-Gandara J, Capasso R. Bromelain a Potential Bioactive Compound: A Comprehensive Overview from a Pharmacological Perspective. Life. 2021; 11(4):317. https://doi.org/10.3390/life11040317

Chicago/Turabian Style

Chakraborty, Arka Jyoti, Saikat Mitra, Trina E. Tallei, Abu Montakim Tareq, Firzan Nainu, Donatella Cicia, Kuldeep Dhama, Talha Bin Emran, Jesus Simal-Gandara, and Raffaele Capasso. 2021. "Bromelain a Potential Bioactive Compound: A Comprehensive Overview from a Pharmacological Perspective" Life 11, no. 4: 317. https://doi.org/10.3390/life11040317

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop