Announcements

We are delighted to share a collection of highly viewed papers in the Section “Nanomedicine and Nanobiology” that were published in Biomedicines (ISSN 2227-9059), latest Impact Factor 4.5, CiteScore 7.8) in 2024–2025. In addition, some Special Issues on this topic are currently open for submission. The following is a list of articles and Special Issues that we believe may be of interest to you:

The list of relevant papers can be seen below:

1. “Advancing Cancer Treatment: Enhanced Combination Therapy through Functionalized Porous Nanoparticles”
by Kibeom Kim and Myoung-Hwan Park
Biomedicines 2024, 12(2), 326; https://doi.org/10.3390/biomedicines12020326
Available online: https://www.mdpi.com/2227-9059/12/2/326

2. “Nanomaterials Based on 2,7,12,17-Tetra-tert-butyl-5,10,15,20-tetraaza-21H,23H-porphine Exhibiting Bifunctional Sensitivity for Monitoring Chloramphenicol and Co2+”
by Ionela Fringu, Diana Anghel, Ion Fratilescu, Camelia Epuran, Mihaela Birdeanu and Eugenia Fagadar-Cosma
Biomedicines 2024, 12(4), 770; https://doi.org/10.3390/biomedicines12040770
Available online: https://www.mdpi.com/2227-9059/12/4/770

3. “Magnetoelectric Extracellular Vesicle Latency-Targeting (MELT) Nanotherapeutic for the Block-Lock-and-Kill HIV Eradication Strategy”
by Mickensone Andre, Nagesh Kolishetti, Adriana Yndart, Arti Vashist, Madhavan Nair and Andrea D. Raymond
Biomedicines 2025, 13(1), 147; https://doi.org/10.3390/biomedicines13010147
Available online: https://www.mdpi.com/2227-9059/13/1/147

4. “Synergistic Effects of Green Nanoparticles on Antitumor Drug Efficacy in Hepatocellular Cancer”
by Mirela Claudia Rîmbu, Liliana Popescu, Mirela Mihăilă, Roxana Colette Sandulovici, Daniel Cord, Carmen-Marinela Mihăilescu, Mona Luciana Gălățanu, Mariana Panțuroiu, Carmen-Elisabeta Manea, Adina Boldeiu et al.
Biomedicines 2025, 13(3), 641; https://doi.org/10.3390/biomedicines13030641
Available online: https://www.mdpi.com/2227-9059/13/3/641

5. “Small Biological Fighters Against Cancer: Viruses, Bacteria, Archaea, Fungi, Protozoa, and Microalgae”
by Pathea Shawnae Bruno, Peter Biggers, Niyogushima Nuru, Nicholas Versaci, Miruna Ioana Chirila, Costel C. Darie and Anca-Narcisa Neagu
Biomedicines 2025, 13(3), 665; https://doi.org/10.3390/biomedicines13030665
Available online: https://www.mdpi.com/2227-9059/13/3/665

6. “Nanosurgery and Bioengineered Regenerative Protocols for the Treatment of Hip Osteoarthritis: A Double-Blind Randomized Controlled Trial as an Alternative to Surgical Hip Replacement”
by Cezary Wasilczyk and Bartosz Wasilczyk
Biomedicines 2025, 13(4), 987; https://doi.org/10.3390/biomedicines13040987
Available online: https://www.mdpi.com/2227-9059/13/4/987

7. “From Jumping Gene to Cancer: Revisiting the Role of JTB Protein”
by Taniya M. Jayaweera, Madhuri Jayathirtha, Krishan Weraduwage, Petra Kraus, Costel C. Darie and Anca-Narcisa Neagu
Biomedicines 2025, 13(7), 1705; https://doi.org/10.3390/biomedicines13071705
Available online: https://www.mdpi.com/2227-9059/13/7/1705

Special Issues:

To acknowledge the above authors’ excellent contributions, we are happy to provide a full waiver to each team of the above publications. We also would like to take this opportunity to thank all the research groups that have submitted to Biomedicines. We would appreciate it if you would circulate this document among your colleagues and networks. Furthermore, the following opportunities for collaboration may be of interest to you:

Submitting a manuscript:
The “Nanomedicine and Nanobiology” Section is currently open for submissions. Papers may be submitted via the following link: https://www.mdpi.com/user/manuscripts/upload/?journal=biomedicines.

Joining the Volunteer Reviewer Board:
If you are an active researcher in the fields of biomedicinal research and are interested in joining the Volunteer Reviewer Board of Biomedicines, please do not hesitate to submit your application via the following link: https://susy.mdpi.com/volunteer/profile/edit.

Biomedicines Editorial Office

Our portfolio of journals available for publishing up-to-date research in immediate open access format has been further expanded. In June 2026, eleven new journals released their inaugural issues and two transferred journals released their first issue as part of MDPI, covering the subjects of environmental & earth sciences, chemistry & materials science, public health & healthcare, engineering, medicine & pharmacology, and biology & life sciences. 

We extend our gratitude to the Editors-in-Chief, Associate Editors, and Editorial Board Members who will shape the future course of these new journals. Each journal is dedicated to upholding strong editorial standards through a thorough peer review process, enabling impactful open access scholarship. 

Please feel free to browse and discover more about the new journals below. 

We would like to thank everyone who has supported the development of open access publishing. If you would like to create a new journal, you are welcome to send an application here or contact the New Journal Committee (newjournal-committee@mdpi.com).

The “Biomedical Engineering and Materials” Section publishes reviews and original peer-reviewed papers which aim to cover studies of the preparation, performance, and evaluation of biomaterials; the chemical, physical, toxicological, and mechanical behavior of materials in physiological environments; and the response of blood and tissues to biomaterials. It also covers biomedical engineering approaches as solutions to clinical practice. In this context, we are pleased to feature some recently published papers on biomedical engineering and materials in Biomedicines (ISSN 2227-9059), which will provide valuable insights into this exciting field.

1. “Resveratrol-Loaded Solid Lipid Nanoparticles Reinforced Hyaluronic Hydrogel: Multitarget Strategy for the Treatment of Diabetes-Related Periodontitis”
by Raffaele Conte, Anna Valentino, Fabrizia Sepe, Francesco Gianfreda, Roberta Condò, Loredana Cerroni, Anna Calarco and Gianfranco Peluso
Biomedicines 2025, 13(5), 1059; https://doi.org/10.3390/biomedicines13051059
Available online: https://www.mdpi.com/2227-9059/13/5/1059

2. “Transimpedance Matrix Measurement (TIM) Parameters Evaluation for the Assessment of Cochlear Implant Electrode Placement and Modiolar Proximity in Children”
by Katarzyna Radomska, Marcin Talar, Karolina Haber, Paulina Mierzwińska-Dolny, Andrew J. Fishman and Józef Mierzwiński
Biomedicines 2025, 13(2), 319; https://doi.org/10.3390/biomedicines13020319
Available online: https://www.mdpi.com/2227-9059/13/2/319

3. “Sonidegib Inhibits the Adhesion of Acute Myeloid Leukemia to the Bone Marrow in Hypoxia: An Optical Tweezer Study”
by Katarzyna Gdesz-Birula, Sławomir Drobczyński, Krystian Sarat and Kamila Duś-Szachniewicz
Biomedicines 2025, 13(3), 578; https://doi.org/10.3390/biomedicines13030578
Available online: https://www.mdpi.com/2227-9059/13/3/578

4. “Residual TPO Content of Photopolymerized Additively Manufactured Dental Occlusal Splint Materials”
by Philipp Messer-Hannemann, Max Wienhold, Hoda Esbak, Alexander Brunner, Andreas Schönebaum, Falk Schwendicke and Susanne Effenberger
Biomedicines 2025, 13(1), 44; https://doi.org/10.3390/biomedicines13010044
Available online: https://www.mdpi.com/2227-9059/13/1/44

5. “Safety and Effectiveness of Triclosan-Coated Polydioxanone (PDS Plus) versus Uncoated Polydioxanone (PDS II) Sutures for Prevention of Surgical Site Infection after Hypospadias Repair in Children: A 10-Year Single Center Experience with 550 Hypospadias”
by Zenon Pogorelić, Lana Stričević, Sara Elezović Baloević, Jakov Todorić and Dražen Budimir
Biomedicines 2024, 12(3), 583; https://doi.org/10.3390/biomedicines12030583
Available online: https://www.mdpi.com/2227-9059/12/3/583

6. “Systemic Ozone Therapy Improves Oral Hard and Soft Tissue Healing in Medication-Related Osteonecrosis of the Jaw (MRONJ): A Study in Senescent Female Rats”
by Leonardo Alan Delanora, Tiburtino José de Lima Neto, Tiago Esgalha da Rocha, Glauco Rodrigues Carmo Silveira, Liran Levin, Jamil Awad Shibli, Edilson Ervolino, Carlos Fernando Mourão and Leonardo P. Faverani
Biomedicines 2025, 13(5), 1248; https://doi.org/10.3390/biomedicines13051248
Available online: https://www.mdpi.com/2227-9059/13/5/1248

7. “PET-Assessed Metabolic Tumor Volume Across the Spectrum of Solid-Organ Malignancies: A Review of the Literature”
by Anusha Agarwal, Chase J. Wehrle, Sangeeta Satish, Paresh Mahajan, Suneel Kamath, Shlomo Koyfman, Wen Wee Ma, Maureen Linganna, Jamak Modaresi Esfeh, Charles Miller et al.
Biomedicines 2025, 13(1), 123; https://doi.org/10.3390/biomedicines13010123
Available online: https://www.mdpi.com/2227-9059/13/1/123

8. “Multiparametric Ultrasound in the Differential Diagnosis of Soft Tissue Tumors: A Comprehensive Review”
by Fabrizio Termite, Linda Galasso, Giacomo Capece, Federica Messina, Giorgio Esposto, Maria Elena Ainora, Irene Mignini, Raffaele Borriello, Raffaele Vitiello, Giulio Maccauro et al.
Biomedicines 2025, 13(7), 500; https://doi.org/10.3390/biomedicines13071786
Available online: https://www.mdpi.com/2227-9059/13/7/1786

9. “Comparative Analysis of Proximal Tubule Cell Sources for In Vitro Studies of Renal Proximal Tubule Toxicity”
by Courtney Sakolish, Han-Hsuan D. Tsai, Hsing-Chieh Lin, Piyush Bajaj, Remi Villenave, Stephen S. Ferguson, Jason P. Stanko, Richard A. Becker, Philip Hewitt, Weihsueh A. Chiu et al.
Biomedicines 2025, 13(3), 563; https://doi.org/10.3390/biomedicines13030563
Available online: https://www.mdpi.com/2227-9059/13/3/563

10. “Influence of Ultrasound Stimulation on the Viability, Proliferation and Protein Expression of Osteoblasts and Periodontal Ligament Fibroblasts”
by Selma Pascoal, Sofia Oliveira, Francisca Monteiro, Jorge Padrão, Rita Costa, Andrea Zille, Susana O. Catarino, Filipe S. Silva, Teresa Pinho and Óscar Carvalho
Biomedicines 2024, 12(2), 361; https://doi.org/10.3390/biomedicines12020361
Available online: https://www.mdpi.com/2227-9059/12/2/361

To acknowledge the above authors’ excellent contributions, we are happy to provide a full waiver to each team of the above publications. We also would like to take this opportunity to thank all the research groups that have submitted to Biomedicines. We would appreciate it if you would circulate this document among your colleagues and networks. Furthermore, the following opportunities for collaboration may be of interest to you:

Submitting a manuscript:
This Section is currently open for submissions. Papers may be submitted via the following link:
https://www.mdpi.com/user/manuscripts/upload/?journal=biomedicines.  

Joining the Volunteer Reviewer Board:
If you are an active researcher in the fields of biomedicinal research and are interested in joining the Volunteer Reviewer Board of Biomedicines, please do not hesitate to submit your application via the following link: https://susy.mdpi.com/volunteer/profile/edit.

Biomedicines Editorial Office

The “Cell Biology and Pathology” Section covers all aspects of this general field, from molecular machines that enable or adversely modify cell function to the pathology of complete organisms. Both review articles and original research contributions are welcome, so long as they conform to the highest scientific standards. Contributions that explore the origin of diseases at the molecular level, such as structural, biochemical, and genetic studies of receptors, oncogenes, tumor suppressors and regulatory proteins, signal pathways, and RNA/DNA, as well as articles that propose new routes for the cure and prevention of diseases, are of particular interest. Cutting-edge diagnostic tools ranging from PCR to magnetic resonance, as applied to the detection of cellular or organismic pathological dysfunctions on all levels, will be accepted. In this context, we are pleased to feature some recently published papers from the “Cell Biology and Pathology” Section in Biomedicines (ISSN 2227-9059), which provide valuable insights into this exciting field.

1. “Plantar Fasciitis Pathophysiology and the Potential Role of Mesenchymal Stem Cell-Derived Extracellular Vesicles as Therapy”
by Kevin Liebmann, D. Wood Kimbrough, Thomas M. Best, Dimitrios Kouroupis and Solangel Rodriguez Materon
Biomedicines 2025, 13(7), 1528; https://doi.org/10.3390/biomedicines13071528
Available online: https://www.mdpi.com/2227-9059/13/7/1528

2. “Evolution of Light-Sensitive Proteins in Optogenetic Approaches for Vision Restoration: A Comprehensive Review”
by Kamil Poboży, Tomasz Poboży, Paweł Domański, Michał Derczyński, Wojciech Konarski and Julia Domańska-Poboża
Biomedicines 2025, 13(2), 429; https://doi.org/10.3390/biomedicines13020429
Available online: https://www.mdpi.com/2227-9059/13/2/429

3. “Beyond Amyloid and Tau: The Critical Role of Microglia in Alzheimer’s Disease Therapeutics”
by Daniela Dias and Renato Socodato
Biomedicines 2025, 13(2), 279; https://doi.org/10.3390/biomedicines13020279
Available online: https://www.mdpi.com/2227-9059/13/2/279

4. “Chronic Inflammation and Immune Dysregulation in Metabolic-Dysfunction-Associated Steatotic Liver Disease Progression: From Steatosis to Hepatocellular Carcinoma”
by Young-Min Jee, Jeong-Yoon Lee and Tom Ryu
Biomedicines 2025, 13(5), 1260; https://doi.org/10.3390/biomedicines13051260
Available online: https://www.mdpi.com/2227-9059/13/5/1260

5. “Advanced Research in the Pathophysiology of Venous Thromboembolism–Acute Pulmonary Embolism”
by Anna M. Imiela, Joanna Kucharska, Franciszek Kukliński, Teresa Fernandez Moreno, Konrad Dzik and Piotr Pruszczyk
Biomedicines 2025, 13(4), 906; https://doi.org/10.3390/biomedicines13040906
Available online: https://www.mdpi.com/2227-9059/13/4/906

6. “Extracorporeal Cytokine Adsorption in Sepsis: Current Evidence and Future Perspectives”
by Matteo Guarino, Anna Costanzini, Francesco Luppi, Martina Maritati, Carlo Contini, Roberto De Giorgio and Michele Domenico Spampinato
Biomedicines 2025, 13(7), 1684; https://doi.org/10.3390/biomedicines13071684
Available online: https://www.mdpi.com/2227-9059/13/7/1684

7. “Mesenchymal Stem Cell Secretome: Potential Applications in Human Infertility Caused by Hormonal Imbalance, External Damage, or Immune Factors”
by Katerina Kavaldzhieva, Nikola Mladenov, Maya Markova and Kalina Belemezova
Biomedicines 2025, 13(3), 586; https://doi.org/10.3390/biomedicines13030586
Available online: https://www.mdpi.com/2227-9059/13/3/586

8. “Neuroinflammation at the Dorsolateral Inferior Medulla: A Possible Central Nervous System Localization for POTS and Long COVID”
by Svetlana Blitshteyn
Biomedicines 2025, 13(1), 166; https://doi.org/10.3390/biomedicines13010166
Available online: https://www.mdpi.com/2227-9059/13/1/166

9. “Interferons in Autoimmunity: From Loss of Tolerance to Chronic Inflammation”
by Grigore Mihaescu, Gratiela Gradisteanu Pircalabioru, Claudiu Natanael Roznovan, Lia-Mara Ditu, Mihaela Maria Comanici and Octavian Savu
Biomedicines 2025, 13(10), 2472; https://doi.org/10.3390/biomedicines13102472
Available online: https://www.mdpi.com/2227-9059/13/10/2472

10. “Non-Invasive Retinal Biomarkers for Early Diagnosis of Alzheimer’s Disease”
by Snježana Kaštelan, Antonela Gverović Antunica, Velibor Puzović, Ana Didović Pavičić, Samir Čanović, Petra Kovačević, Pia Antonia Franciska Vučemilović and Suzana Konjevoda
Biomedicines 2025, 13(2), 283; https://doi.org/10.3390/biomedicines13020283
Available online: https://www.mdpi.com/2227-9059/13/2/283

To acknowledge the above authors’ excellent contributions, we are happy to provide a full waiver to each team of the above publications. We also would like to take this opportunity to thank all the research groups that have submitted to Biomedicines. We would appreciate it if you would circulate this document among your colleagues and networks. Furthermore, the following opportunities for collaboration may be of interest to you:

Submitting a manuscript:
This Section is currently open for submissions. Papers may be submitted via the following link:
https://www.mdpi.com/user/manuscripts/upload/?journal=biomedicines.

Joining the Volunteer Reviewer Board:
If you are an active researcher in the field of biomedicinal research and are interested in joining the Volunteer Reviewer Board of Biomedicines, please do not hesitate to submit your application via the following link: https://susy.mdpi.com/volunteer/profile/edit.

Biomedicines Editorial Office

The “Cancer Biology and Oncology” Section publishes reviews and original peer-reviewed papers of a high scientific standard, covering all the aspects of innovative cancer therapies. Papers aim to uncover novel therapeutic approaches toward overcoming conventional anticancer drug resistance, a better understanding of the interrelations between cancer and metabolism as well as tumor and microenvironment, along with the discovery of novel diagnostic and prognostic makers. Topics include, but are not limited to, in vitro and in vivo cancer therapeutic responses, targeted therapies (including metabolism and immunotherapy, such involving CAR-T cells), identification of novel therapeutic targets, and evaluation of novel diagnosis and prognosis markers and the assessment of their impact on morphological, phenotypical, and molecular classifications.

1. “Advances in Therapy for Urothelial and Non-Urothelial Subtype Histologies of Advanced Bladder Cancer: From Etiology to Current Development”
by Whi-An Kwon, Ho Kyung Seo, Geehyun Song, Min-Kyung Lee and Weon Seo Park
Biomedicines 2025, 13(1), 86; https://doi.org/10.3390/biomedicines13010086
Available online: https://www.mdpi.com/2227-9059/13/1/86

2. “Measurable Residual Disease Detection in Acute Myeloid Leukemia: Current Challenges and Future Directions”
by Jennifer Moritz, Antonia Schwab, Andreas Reinisch, Armin Zebisch, Heinz Sill and Albert Wölfler
Biomedicines 2024, 12(3), 599; https://doi.org/10.3390/biomedicines12030599
Available online: https://www.mdpi.com/2227-9059/12/3/599

3. “Advancing Head and Neck Cancer Therapies: From Conventional Treatments to Emerging Strategies”
by Aleksandra Mordzińska-Rak, Ilona Telejko, Grzegorz Adamczuk, Tomasz Trombik, Andrzej Stepulak and Ewa Błaszczak
Biomedicines 2025, 13(5), 1046; https://doi.org/10.3390/biomedicines13051046
Available online: https://www.mdpi.com/2227-9059/13/5/1046

4. “The Role of αvβ3 Integrin in Cancer Therapy Resistance”
by Bianca Cruz Pachane and Heloisa S. Selistre-de-Araujo
Biomedicines 2024, 12(6), 1163; https://doi.org/10.3390/biomedicines12061163
Available online: https://www.mdpi.com/2227-9059/12/6/1163

5. “Circulating Tumor Cells: Origin, Role, Current Applications, and Future Perspectives for Personalized Medicine”
by Maria Cristina Rapanotti, Tonia Cenci, Maria Giovanna Scioli, Elisa Cugini, Silvia Anzillotti, Luca Savino, Deborah Coletta, Cosimo Di Raimondo, Elena Campione, Mario Roselli et al.
Biomedicines 2024, 12(9), 2137; https://doi.org/10.3390/biomedicines12092137
Available online: https://www.mdpi.com/2227-9059/12/9/2137

6. “Breast Cancer Molecular Subtype Prediction: A Mammography-Based AI Approach”
by Ana M. Mota, João Mendes and Nuno Matela
Biomedicines 2024, 12(6), 1371; https://doi.org/10.3390/biomedicines12061371
Available online: https://www.mdpi.com/2227-9059/12/6/1371

7. “Uveal Melanoma: Comprehensive Review of Its Pathophysiology, Diagnosis, Treatment, and Future Perspectives”
by Merve Kulbay, Emily Marcotte, Raheem Remtulla, Tsz Hin Alexander Lau, Manuel Paez-Escamilla, Kevin Y. Wu and Miguel N. Burnier, Jr
Biomedicines 2024, 12(8), 1758; https://doi.org/10.3390/biomedicines12081758
Available online: https://www.mdpi.com/2227-9059/12/8/1758

8. “The Role of NK Cells in Cancer Immunotherapy: Mechanisms, Evasion Strategies, and Therapeutic Advances”
by Paula Morcillo-Martín-Romo, Javier Valverde-Pozo, María Ortiz-Bueno, Maurizio Arnone, Laura Espinar-Barranco, Celia Espinar-Barranco and María Eugenia García-Rubiño
Biomedicines 2025, 13(4), 857; https://doi.org/10.3390/biomedicines13040857
Available online: https://www.mdpi.com/2227-9059/13/4/857

9. “Predictive Value and Therapeutic Significance of Somatic BRCA Mutation in Solid Tumors”
by Gyongyver Szentmartoni, Dorottya Mühl, Renata Csanda, Attila Marcell Szasz, Zoltan Herold and Magdolna Dank
Biomedicines 2024, 12(3), 593; https://doi.org/10.3390/biomedicines12030593
Available online: https://www.mdpi.com/2227-9059/12/3/593

10. “Meningioma: Novel Diagnostic and Therapeutic Approaches”
by Carlen A. Yuen, Michelle Zheng, Max A. Saint-Germain and David O. Kamson
Biomedicines 2025, 13(3), 659; https://doi.org/10.3390/biomedicines13030659
Available online: https://www.mdpi.com/2227-9059/13/3/659

To acknowledge the above authors’ excellent contributions, we are happy to provide a full waiver to each team of the above publications. We also would like to take this opportunity to thank all the research groups that have submitted to Biomedicines. We would appreciate it if you would circulate this document among your colleagues and networks. Furthermore, the following opportunities for collaboration may be of interest to you:

Submitting a manuscript:
This Section is currently open for submissions. Papers may be submitted via the following link:
https://www.mdpi.com/user/manuscripts/upload/?journal=biomedicines.

Joining the Volunteer Reviewer Board:
If you are an active researcher in the fields of biomedicinal research and are interested in joining the Volunteer Reviewer Board of Biomedicines, please do not hesitate to submit your application via the following link: https://susy.mdpi.com/volunteer/profile/edit.

Biomedicines Editorial Office

Peer review is the invisible foundation of academic progress. The 2025 MDPI Top Reviewers are some of the key experts who helped build it.

We are honored to recognize 1000 individuals from our global community of 210,000 reviewers across 67 countries and territories—chosen for their commitment to rigorous, constructive peer review and the consistency of their contributions throughout 2025.

The Top Reviewers provided constructive and impartial feedback that makes research stronger and more impactful, and we are grateful for it.

The names of these reviewers are listed below in alphabetical order by first name:

(Note: we respected all privacy preferences, with part of nominees opting for limited attribution.)

This Section publishes reviews and original peer-reviewed papers of a high scientific level covering all the aspects of immunology and oncoimmunology. Papers aim to uncover the modulations of the immune system, active and passive immunotherapies, diagnostic tests based on specific markers and the use of new technologies to identify novel predictive factors to respond to immunotherapy. Topics include, but are not limited to, in vivo/in vitro immune responses research; targeted therapies (including antibody research and vaccine research); virotherapy and oncolytic vaccines; use of nanoparticles and microvesicles for developing immunotherapeutics, etc.

1. “Gender Differences in the Interplay between Vitamin D and Microbiota in Allergic and Autoimmune Diseases”
by Giuseppe Murdaca, Luca Tagliafico, Elena Page, Francesca Paladin and Sebastiano Gangemi
Biomedicines 2024, 12(5), 1023; https://doi.org/10.3390/biomedicines12051023
Available online: https://www.mdpi.com/2227-9059/12/5/1023

2. “microRNA–mRNA Networks Linked to Inflammation and Immune System Regulation in Inflammatory Bowel Disease”
by Carina de F. de Síbia, Ana E. V. Quaglio, Ellen C. S. de Oliveira, Jéssica N. Pereira, Jovita R. Ariede, Rainer M. L. Lapa, Fábio E. Severino, Patricia P. Reis, Lígia Y. Sassaki and Rogerio Saad-Hossne
Biomedicines 2024, 12(2), 422; https://doi.org/10.3390/biomedicines12020422
Available online: https://www.mdpi.com/2227-9059/12/2/422

3. “Targeting Sepsis: Disease Tolerance, Immune Resilience, and Compartmentalized Immunity”
by Alexis Garduno and Ignacio Martín-Loeches
Biomedicines 2024, 12(11), 2420; https://doi.org/10.3390/biomedicines12112420
Available online: https://www.mdpi.com/2227-9059/12/11/2420

4. “Unraveling TAFRO Syndrome: An In-Depth Look at the Pathophysiology, Management, and Future Perspectives”
by Juan Carlos Caballero, Nazaret Conejero, Laura Solan, Francisco Javier Diaz de la Pinta, Raul Cordoba and Alberto Lopez-Garcia
Biomedicines 2024, 12(5), 1076; https://doi.org/10.3390/biomedicines12051076
Available online: https://www.mdpi.com/2227-9059/12/5/1076

5. “The Importance of Predictive Biomarkers and Their Correlation with the Response to Immunotherapy in Solid Tumors—Impact on Clinical Practice”
by Raluca IoanaMihaila, Adelina Silvana Gheorghe, Daniela Luminita Zob and Dana Lucia Stanculeanu
Biomedicines 2024, 12(9), 2146; https://doi.org/10.3390/biomedicines12092146
Available online: https://www.mdpi.com/2227-9059/12/9/2146

6. “Regulation of Airway Epithelial-Derived Alarmins in Asthma: Perspectives for Therapeutic Targets”
by Ravneet K. Hansi, Maral Ranjbar, Christiane E. Whetstone and Gail M. Gauvreau
Biomedicines 2024, 12(10), 2312; https://doi.org/10.3390/biomedicines12102312
Available online: https://www.mdpi.com/2227-9059/12/10/2312

7. “Prognostic Significance of Plasma Neutrophil Extracellular Trap Levels in Patients with Non-Small Cell Lung Cancer Treated with Immune Checkpoint Inhibitors”
by Shun Horaguchi, Yoshiro Nakahara, Yuka Igarashi, Taku Kouro, Feifei Wei, Kenta Murotani, Seiichi Udagawa, Naoko Higashijima, Norikazu Matsuo, Shuji Murakami et al.
Biomedicines 2024, 12(8), 1831; https://doi.org/10.3390/biomedicines12081831
Available online: https://www.mdpi.com/2227-9059/12/8/1831

8. “CD8+ T Cell Subsets as Biomarkers for Predicting Checkpoint Therapy Outcomes in Cancer Immunotherapy”
by Rosaely Casalegno Garduño, Alf Spitschak, Tim Pannek and Brigitte M. Pützer
Biomedicines 2025, 13(4), 930; https://doi.org/10.3390/biomedicines13040930
Available online: https://www.mdpi.com/2227-9059/13/4/930

9. “Exploring Neutrophil Heterogeneity and Plasticity in Health and Disease”
by Conny Gysemans, Mateson Beya, Erika Pedace and Chantal Mathieu
Biomedicines 2025, 13(3), 597; https://doi.org/10.3390/biomedicines13030597
Available online: https://www.mdpi.com/2227-9059/13/3/597

10. “The Role of the Immune System in Pathobiology and Therapy of Myocarditis: A Review”
by Cristina Vicenzetto, Andrea Silvio Giordani, Caterina Menghi, Anna Baritussio, Maria Grazia Peloso Cattini, Elena Pontara, Elisa Bison, Stefania Rizzo, Monica De Gaspari, Cristina Basso et al.
Biomedicines 2024, 12(6), 1156; https://doi.org/10.3390/biomedicines12061156
Available online: https://www.mdpi.com/2227-9059/12/6/1156

To acknowledge the above authors’ excellent contributions, we are happy to provide a full waiver to each team of the above publications. We also would like to take this opportunity to thank all the research groups that have submitted to Biomedicines (ISSN 2227-9059). We would appreciate it if you would circulate this document among your colleagues and networks. Furthermore, the following opportunities for collaboration may be of interest to you:

Submitting a manuscript:
This Section is currently open for submissions. Papers may be submitted via the following link: https://www.mdpi.com/user/manuscripts/upload/?journal=biomedicines.

Joining the Volunteer Reviewer Board:
If you are an active researcher in the fields of biomedicinal research and are interested in joining the Volunteer Reviewer Board of Biomedicines, please do not hesitate to submit your application via the following link: https://susy.mdpi.com/volunteer/profile/edit.

Biomedicines Editorial Office

The “Drug Discovery, Development and Delivery” Section publishes original and innovative scientific papers, as well as review papers. It is organized into topics, mainly covering drug discovery, drug design, basic and clinical pharmacology, formulation and delivery, toxicology, and natural products research. Studies on substances obtained from natural sources, as well as their synthetic derivatives, are fully within the Section’s scope, provided that the compounds are chemically well defined. For research involving complex natural product mixtures, a suitable level of analytical characterization—such as through HPLC, MS, LC–MS, HPLC–MS, or NMR—is expected. In addition to identification, chemistry, or analytical studies, manuscripts should also include in vitro and/or in vivo testing. Moreover, authors are encouraged to explore and discuss the cellular or molecular mechanisms of the natural compounds or characterized extracts.

1. “Cannabinoids in Chronic Pain Management: A Review of the History, Efficacy, Applications, and Risks”
by Brooks W. Johnson, Natalie H. Strand, John C. Raynak, Christian Jara, Kisanet Habtegiorgis, Brennan A. Hand, Sang Hong and Jillian A. Maloney
Biomedicines 2025, 13(3), 530; https://doi.org/10.3390/biomedicines13030530
Available online: https://www.mdpi.com/2227-9059/13/3/530

2. “Whey Proteins and Bioactive Peptides: Advances in Production, Selection and Bioactivity Profiling”
by Anna Luparelli, Daniela Trisciuzzi, William Matteo Schirinzi, Leonardo Caputo, Leonardo Smiriglia, Laura Quintieri, Orazio Nicolotti and Linda Monaci
Biomedicines 2025, 13(6), 1311; https://doi.org/10.3390/biomedicines13061311
Available online: https://www.mdpi.com/2227-9059/13/6/1311

3. “Transepidermal Delivery of Calcium Hydroxyapatite (CaHA) Microneedling: A Novel Approach for Inducing Collagen Types III and IV”
by Andréia Luiza Oliveira Costa, Fernando Veloso Caldeira Barcellos, Maria Tereza Scardua Mariano, Eloá Mangabeira Santos, Lorena dos Reis Pereira Queiroz, Erivelton Pereira Santos, Vitória Regina Oliveira de Melo, Sérgio Henrique Sousa Santos, Lucyana Conceição Farias, Alfredo Maurício Batista de Paula et al.
Biomedicines 2025, 13(10), 2463; https://doi.org/10.3390/biomedicines13102463
Available online: https://www.mdpi.com/2227-9059/13/10/2463

4. “Biotechnology Production of Cell Biomass from the Endangered Kickxia elatine (L.) Dumort: Its Untargeted Metabolomic Analysis and Cytotoxic Potential Against Melanoma Cells”
by Anastasia Aliesa Hermosaningtyas, Ewa Totoń, Anna Budzianowska, Natalia Lisiak, Aleksandra Romaniuk-Drapała, Dariusz Kruszka, Monika Rewers and Małgorzata Kikowska
Biomedicines 2025, 13(6), 1382; https://doi.org/10.3390/biomedicines13061382
Available online: https://www.mdpi.com/2227-9059/13/6/1382

5. “Enhanced Stability of Multi-Functionalized Gold Nanoparticles and Potential Anticancer Efficacy on Human Cervical Cancer Cells”
by Aurora Mocanu, Madalina Anca Ujica, Ossi Horovitz, Gheorghe Tomoaia, Olga Soritau, Cristina Teodora Dobrota, Cristina Roxana Popa, Attila Kun, Horea-Rares-Ciprian Benea, Ionel Marius Mang et al.
Biomedicines 2025, 13(8), 1861; https://doi.org/10.3390/biomedicines13081861
Available online: https://www.mdpi.com/2227-9059/13/8/1861

6. “Affordable mRNA Novel Proteins, Recombinant Protein Conversions, and Biosimilars—Advice to Developers and Regulatory Agencies”
by Sarfaraz K. Niazi
Biomedicines 2025, 13(1), 97; https://doi.org/10.3390/biomedicines13010097
Available online: https://www.mdpi.com/2227-9059/13/1/97

7. “Vitexin as a Potential Antidysmenorrheic Agent: Development of a ZIF-8-Based Immediate-Release System and Evaluation via In Vivo and In Silico Approaches”
by José Marcos Teixeira de Alencar Filho, Ana Rita de Sousa França, Luana Beatriz Rocha da Silva, Pedrita Alves Sampaio, Emanuella Chiara Valença Pereira, Ademar Rocha da Silva, Milenna Victória Valentim de Oliveira Alencar, Tarcísio Cícero de Lima Araújo, Pedro Modesto Nascimento Menezes, Salvana Priscylla Manso Costa et al.
Biomedicines 2025, 13(11), 2602; https://doi.org/10.3390/biomedicines13112602
Available online: https://www.mdpi.com/2227-9059/13/11/2602

8. “Amburana cearensis (Cumaru) and Its Active Principles as Source of Anti-Leishmania Drugs: Immunomodulatory Activity of Coumarin (1,2-Benzopyrone)”
by Naya Lúcia de Castro Rodrigues, Elizama Shirley Silveira, Francisco Rafael Marciano Fonseca, Ticiana Monteiro Abreu, Edilberto Rocha Silveira, Ana Bruna de Araújo, Maria Jania Teixeira and Luzia Kalyne Almeida Moreira Leal
Biomedicines 2025, 13(4), 979; https://doi.org/10.3390/biomedicines13040979
Available online: https://www.mdpi.com/2227-9059/13/4/979

9. “Betulinic Acid ω-Triphenylphosphonium Alkyl Esters: Antiproliferative Activities and In Silico Pharmacokinetic Profiles”
by Cristian Suárez-Rozas, Claudia Duarte-Salinas, Javier Gajardo-De la Fuente, Paola Salgado-Figueroa, Julio Salas-Norambuena, Bruce K. Cassels, Cristina Theoduloz, José A. Jara, Sebastián Fuentes-Retamal, Paola R. Campodónico et al.
Biomedicines 2025, 13(7), 1539; https://doi.org/10.3390/biomedicines13071539
Available online: https://www.mdpi.com/2227-9059/13/7/1539

10. “Effects of Methionine and Glutathione on Acute Ototoxicity Induced by Amikacin and Furosemide in an Animal Model of Hearing Threshold Decrease”
by Marek Zadrożniak, Marcin Szymański and Jarogniew J. Luszczki
Biomedicines 2025, 13(6), 1476; https://doi.org/10.3390/biomedicines13061476
Available online: https://www.mdpi.com/2227-9059/13/6/1476

To acknowledge the above authors’ excellent contributions, we are happy to provide a full waiver to each team of the above publications. We also would like to take this opportunity to thank all the research groups that have submitted to Biomedicines (ISSN 2227-9059). We would appreciate it if you would circulate this document among your colleagues and networks. Furthermore, the following opportunities for collaboration may be of interest to you:

Submitting a manuscript:
This Section is currently open for submissions. Papers may be submitted via the following link: https://www.mdpi.com/user/manuscripts/upload/?journal=biomedicines.

Joining the Volunteer Reviewer Board:
If you are an active researcher in the fields of biomedicinal research and are interested in joining the Volunteer Reviewer Board of Biomedicines, please do not hesitate to submit your application via the following link: https://susy.mdpi.com/volunteer/profile/edit.

Biomedicines Editorial Office

The “Endocrinology and Metabolism Research” Section publishes original and innovative scientific papers, as well as comprehensive review papers. In this context, we are pleased to feature some recently published papers on gene regulation, cell biology, signaling, mutations, growth factors, cytokines, hormone receptors, hormone action and regulation, developmental endocrinology, genetic endocrinology, endocrine diseases (diabetes, obesity, osteoporosis, hyperthyroidism, etc.), and metabolic diseases in Biomedicines (ISSN 2227-9059), which will provide valuable insights into this exciting field.

1. “Diabetic Foot Ulcers: Pathophysiology, Immune Dysregulation, and Emerging Therapeutic Strategies”
by John Dawi, Kevin Tumanyan, Kirakos Tomas, Yura Misakyan, Areg Gargaloyan, Edgar Gonzalez, Mary Hammi, Serly Tomas and Vishwanath Venketaraman
Biomedicines 2025, 13(5), 1076; https://doi.org/10.3390/biomedicines13051076
Available online: https://www.mdpi.com/2227-9059/13/5/1076

2. “The Association between the Firmicutes/Bacteroidetes Ratio and Body Mass among European Population with the Highest Proportion of Adults with Obesity: An Observational Follow-Up Study from Croatia”
by Andrija Karačić, Ira Renko, Željko Krznarić, Sanja Klobučar and Ana-Marija Liberati Pršo
Biomedicines 2024, 12(10), 2263; https://doi.org/10.3390/biomedicines12102263
Available online: https://www.mdpi.com/2227-9059/12/10/2263

3. “Omentin: A Key Player in Glucose Homeostasis, Atheroprotection, and Anti-Inflammatory Potential for Cardiovascular Health in Obesity and Diabetes”
by Cristina M. Sena
Biomedicines 2024, 12(2), 284; https://doi.org/10.3390/biomedicines12020284
Available online: https://www.mdpi.com/2227-9059/12/2/284

4. “mTOR Dysregulation, Insulin Resistance, and Hypertension”
by Silviu Marcel Stanciu, Mariana Jinga, Daniela Miricescu, Constantin Stefani, Remus Iulian Nica, Iulia-Ioana Stanescu-Spinu, Ileana Adela Vacaroiu, Maria Greabu and Silvia Nica
Biomedicines 2024, 12(8), 1802; https://doi.org/10.3390/biomedicines12081802
Available online: https://www.mdpi.com/2227-9059/12/8/1802

5. “The Iron Metabolism with a Specific Focus on the Functioning of the Nervous System”
by Monika Kulaszyńska, Sebastian Kwiatkowski and Karolina Skonieczna-Zydecka
Biomedicines 2024, 12(3), 595; https://doi.org/10.3390/biomedicines12030595
Available online: https://www.mdpi.com/2227-9059/12/3/595

6. “Integrated Management of Cardiovascular–Renal–Hepatic–Metabolic Syndrome: Expanding Roles of SGLT2is, GLP-1RAs, and GIP/GLP-1RAs”
by Nikolaos Theodorakis and Maria Nikolaou
Biomedicines 2025, 13(1), 135; https://doi.org/10.3390/biomedicines13010135
Available online: https://www.mdpi.com/2227-9059/13/1/135

7. “Factors Associated with the Development of Depression and the Influence of Obesity on Depressive Disorders: A Narrative Review”
by Adriano Alberti, David Richer Araujo Coelho, Willians Fernando Vieira, Betine Moehlecke Iser, Rose Meiry Fernandez Lampert, Eliane Traebert, Bruna Becker da Silva, Bruna Hoffmann de Oliveira, Graziela Marques Leão, Gabriela de Souza et al.
Biomedicines 2024, 12(9), 1994; https://doi.org/10.3390/biomedicines12091994
Available online: https://www.mdpi.com/2227-9059/12/9/1994

8. “Atherosclerosis and Insulin Resistance: Is There a Link Between Them?”
by Alina Didu Brie, Ruxandra Maria Christodorescu, Roxana Popescu, Ovidiu Adam, Alexandru Tîrziu and Daniel Miron Brie
Biomedicines 2025, 13(6), 1291; https://doi.org/10.3390/biomedicines13061291
Available online: https://www.mdpi.com/2227-9059/13/6/1291

9. “SGLT2 Inhibitors and GLP-1 Receptor Agonists in Cardiovascular–Kidney–Metabolic Syndrome”
by Aryan Gajjar, Arvind Kumar Raju, Amani Gajjar, Mythili Menon, Syed Asfand Yar Shah, Sourbha Dani and Andrew Weinberg
Biomedicines 2025, 13(8), 1924; https://doi.org/10.3390/biomedicines13081924
Available online: https://www.mdpi.com/2227-9059/13/8/1924

10. “MASLD: Prevalence, Mechanisms, and Sex-Based Therapies in Postmenopausal Women”
by Ilaria Milani, Marianna Chinucci, Frida Leonetti and Danila Capoccia
Biomedicines 2025, 13(4), 855; https://doi.org/10.3390/biomedicines13040855
Available online: https://www.mdpi.com/2227-9059/13/4/855

To acknowledge the above authors’ excellent contributions, we are happy to provide a full waiver to each team of the above publications. We also would like to take this opportunity to thank all the research groups that have submitted to Biomedicines (ISSN 2227-9059). We would appreciate it if you would circulate this document among your colleagues and networks. Furthermore, the following opportunities for collaboration may be of interest to you:

Submitting a manuscript:
This Section is currently open for submissions. Papers may be submitted via the following link: https://www.mdpi.com/user/manuscripts/upload/?journal=biomedicines.

Joining the Volunteer Reviewer Board:
If you are an active researcher in the fields of biomedicinal research and are interested in joining the Volunteer Reviewer Board of Biomedicines, please do not hesitate to submit your application via the following link: https://susy.mdpi.com/volunteer/profile/edit.

Biomedicines Editorial Office

A range of MDPI journals will be attending International Congress Center Messe München in Munich, Germany from 28 to 31 August 2026.

Furthermore, 2026 marks MDPI’s third year of partnering with ESC Congress. Centered on the theme “Spotlight on Artificial Intelligence”, the conference explores AI as an auxiliary clinical tool that improves accuracy, workflow speed and patient safety. More than 32,000 delegates joined last year’s event, and MDPI secured 122 valuable contacts on-site.

The following open access journals will be represented at the ESC Congress 2026:

• JCDD;
• JCM;
• Antioxidants;
• Cardiogenetics;
• Cardiovascular Medicine;
• Hearts;
• IJERPH;
• Medicina;
• AI;
• Biomedicines;
• Clinics and Practice;
• EJIHPE;
• JPM;
• JVD;
• Tomography.

If you are planning to attend the above conference, please do not hesitate to drop by our booth and start a conversation with us; we look forward to meeting you in person and answering any questions that you may have. For more information about the conference, please visit https://www.escardio.org/Congresses-Events/ESC-Congress# or contact the Journal of Cardiovascular Development and Disease Editorial Office at jcdd@mdpi.com.